Average Quality Of Life Score Research Articles

STUDI KOMPARATIF KUALITAS HIDUP IBU HAMIL REMAJA BERDASARKAN STATUS

Background: Teenage pregnancy is a high-risk pregnancy and can cause various social, medical and physical health problems. During teenage pregnancy, there are physical, mental and social changes which are dimensions of quality of life. Many factors related to quality of life including demographic status. Objective: To determine the quality of life of adolescent pregnant women and compare the quality of life based on demographic status Methods: This research is a comparative study conducted at the Sukabumi PONED Public Health Center in October 2019 – November 2020. The population in the study was pregnant women aged less than 20 years, the sample in this study was 34 people with a sampling technique using accidental sampling. The quality of life instrument uses the Short Form-36 (SF 36). Quality of life outcomes were compared based on demographic characteristics, namely education, parity, gestational age, marital status, pregnancy status. Data that were normally distributed were analyzed using the t test, while data that were not normally distributed were analyzed using the Mann Whitney test. Test the normality of the data using the Kolmogorov Smirnov test for the quality of life variable. Results: The average quality of life scores for the domains of physical function, pain, general health, energy, social function, emotional roles, mental health, physical health components, mental health components have an average value above 50. There are differences in scores in several quality domains. life in the respondent group based on gestational age, pregnancy status and marital status with p <0.05. Conclusion: There are differences in several domains of quality of life based on gestational age, pregnancy status and marital status. Keywords: Quality of Life, Teenage Pregnancy

Health-related quality of life in elderly patients with diabetes at Ha Dong traditional medicine hospital.

Background: Health-related quality of life is one of the most widely-used measures to self-assess the effect of the management of chronic disease on health, and monitors the physical, psychological and social aspects of personal health. These data in elderly diabetic Vietnamese is currently limited. Objectives: To measure health-related quality of life in elderly diabetic patients at Ha Dong Traditional Medicine Hospital. Methods: A cross-sectional study was performed in 107 patients aged 60 years or older, who was examined and treated at the Ha Dong Traditional Medicine Hospital. The subjects were interviewed by a designed questionnaire. Health-related quality of life was measured using SF-36 questionnaire. Results: Among 107 participants, the mean age was 66.1 ± 6.4 years; women account for 66.4%. The average duration of diabetes was 9.6 ± 5.0 (years). The percentage of patients with blood glucose control and HbA1c reaching their targets is 44.9% and 62.6%, respectively. The mean number of complications was 1.3 ± 0.7. Average quality of life score of study subjects was: 43.49 ± 9.30. Average score of mental health (49.32 ± 8.58) which was higher than physical health (37.85 ± 10.93) indicates that the patient has a quality of life related to mental health better than physical health. Conclusion: The quality of life for diabetic elderly patients at Ha Dong Traditional Medicine Hospital was not good, especially the quality of life related to physical health. Good control of blood glucose, prevention and treatment of comorbidities and minimizing complications of diabetes help improve the quality of life for patients.

Association between MS-related knowledge, health literacy, self-efficacy, resilience, and quality of life in a large cohort of MS community members: A cross-sectional study

Background: Despite their potential importance, little is known about the associations between multiple sclerosis (MS) knowledge and other outcomes among MS community members. Objective: To examine the relationships between MS-related knowledge, health literacy, self-efficacy, resilience, quality of life (QoL), and MS symptom severity in a cohort of MS community members. Methods: In this cross-sectional study (N = 1993), we assessed a cohort of Understanding MS online course enrolees using means and standard deviations. We evaluated the impact of participant characteristics on outcomes using chi square, t-tests, and linear regression models, and assessed associations between outcomes using Pearson correlation. Results: We found that the total cohort had moderate to high scores on all outcomes. People living with MS had an above average mean MS knowledge score, but below average QoL, resilience, and health literacy scores. The association of MS status with outcome scores was supported by linear regression models. MS knowledge was not correlated with any other outcome for either people living with MS or without MS. Conclusions: MS knowledge was not associated with the other study outcomes, suggesting that educational interventions that solely aim to increase knowledge may be ineffective in improving health-related outcomes within the MS community.

Aspects of the quality of life of children born with the use of assisted reproductive technologies to women of late reproductive age

BACKGROUND: In recent decades, an increasing number of women worldwide have been postponing childbearing, and the birth of children is possible with increasing frequency in late reproductive age only with the use of assisted reproductive technologies. The persistence of this tendency determines the relevance of studying the characteristics of the quality of life of children born as a result of assisted reproductive technologies by women of late reproductive age, as well as subsequent work with factors that affect the quality of life of this group of children.&#x0D; AIM: This study aimed to analyze and determine the characteristics of the quality of life of children born with the use of assisted reproductive technologies by women of late reproductive age.&#x0D; MATERIALS AND METHODS: The main group of subjects consisted of preschool children (46 years old) born to women over 35 years old (249 children), whereas 248 children of the same age were enrolled as a control group. Conception with the use of assisted reproductive technologies was the main distinguishing feature of the main and control groups. Informed consent was obtained from the parents for the participation of children in the study. The protocol was approved by the local ethics committee of the Samara State Medical University of the Ministry of Health of the Russian Federation. A survey was performed using the Pediatric Quality of Life Inventory (validated Russian version 4.0) parental form for age categories of 24 and 57 years, as well as a pediatric version for 57 years of age.&#x0D; RESULTS: The quality of life of the main group had significantly lower indicators compared to the control group, with an average score in the general quality of life of 64.52.5 and 79.53.1 in the main and control group, respective, p=0.047. This is mainly due to the lower values of the communicative aspect and the quality of life in kindergarten. The average quality of life score in the field of communication was 70.44.3 and 83.93.4 in the main group and control group, respectively. Additionally, the average quality of life score in the kindergarten was 40.32.6 and 84.23.3 in the main and control group.&#x0D; CONCLUSIONS: The quality of life of preschool children born with the use of assisted reproductive technologies to women of late reproductive age significantly differs from those in the control group. Children born with the use of assisted reproductive technologies have a comparable quality of life in physical activity and emotional state; however, this group experiences the greatest difficulties in the field of communication, especially in kindergarten with peers. These aspects of functioning require special attention from the parents and pediatricians, as well as adjustments within the health-improving measures that are performed in this group of children.

MO888QUALITY OF LIFE AND QUALITY OF SLEEP IN MAINTENANCE HEMODIALYSIS PATIENTS: REPORTS FROM TWO HEMODIALYSIS CENTERS IN IRAN

Abstract Background and Aims Patients with End Stage Kidney Disease (ESKD) usually tend to have lower Quality of Life (QoL) compared to the general population. The purpose of this study was to determine the QoL and quality of sleep in patients on maintenance hemodialysis (MHD) and its relation with medical factors. Method This descriptive-analytical study was performed on 145 patients on MHD in two hospitals affiliated to Abadan University of Medical Sciences. Patients' QoL was assessed via KDQOL-SF questionnaire. For sleep quality, Pittsburgh Sleep Quality Questionnaire (PSQI) was used. Demographic information of patients, type of vascular access, history of dialysis, and frequency and duration of each dialysis session were collected. The average results of related laboratory tests in the last six months, were also recorded for each patient. Results Of 145 MHD patients, 81 (55%) were men and 64 were women. Most patients (53%) were between 30 and 60 years old. Illiteracy was present in 48 (33%) patients. Unemployed patients accounted for 70% of patients (99) and most of the participants (83.44%) lived in the city. Of 145 patients, 102 (70.34%) were married, 20 (13.79%) were single, and the rest were widows. The mean dialysis adequacy of patients was 1.14, and 53% had dialysis adequacy less than 1.2. The average quality of life score was 66.00 ±13, suggesting a high QoL in this group of patients. literacy was significantly associated with QoL score (P&amp;lt;0.001). Likewise, there was significant association between QoL score and income level (p &amp;lt;.001), the effect of Kidney disease on life (p &amp;lt;.001), working status (p &amp;lt;.009), social functioning (p &amp;lt;.046), and marital status (p &amp;lt;.001). The quality of social interactions was significantly associated with residence location (p &amp;lt;.001). On the other hand, the presence of Kidney disease burden, sexual dysfunction, unemployment, role emotional and role physical, was associated with low QoL scores. We found a significant relationship between hemoglobin level and cognitive function (p &amp;lt;.001, r= .075). In addition, significant relationships between phosphorus levels and physical function (p=.021) and role emotional (P:0.04) were observed. Seemingly, phosphorus levels were inversely related with sexual function in our patients (p &amp;lt;0.001, r= - .013). Our data also suggested that serum calcium levels may have an impact on the patients’ social function (p=.038). The mean score of sleep quality was 7.00±4.00. Most of the patients (61%) had a PSQI&amp;gt;5, indicating a poor sleep quality. High sleep quality (PSQI&amp;lt;5) is significantly associated with low age and high-income level. There was also a significant relationship between the average sleep quality and general health (p &amp;lt;0.001, r= -0.206), social function (p= 0.018, r=-0.208), and energy fatigue (p &amp;lt;0.001, r= -0.309). Conclusion Our study showed that a wide range of determinants, including demographic, socioeconomic and disease-related factors can significantly influence the QoL and sleep quality in ESKD patients undergoing hemodialysis. Among them, modifiable factors including laboratory test results, socioeconomic determinants and psychosocial status should be addressed and accordingly treated and solved. Hence, an improvement in both the QoL and sleep quality of maintenance hemodialysis patients will be expected. Keywords Hemodialysis, Quality of life, Sleep quality, Sociodemographic characteristics.

Exploring the influencing factors of quality of life among the empty nesters in Shanxi, China: a structural equation model

BackgroundAs China’s aging trend intensifies and the proportion of empty nests increases, the health-related quality of life of the elderly is the focus of social attention. Previous studies focused on the quality of life of the elderly, rather than empty nesters, and lacked the discussion of the mechanism of influencing factors. Thus, this study aimed to explore the influencing factors of the quality of life (QOL) and interaction mechanisms among empty nesters in Shanxi Province, China, so as to provide practical reference for improving the QOL of empty nesters.MethodsA total of 4901 empty nesters in Shanxi Province, China, were selected using multi-stage random cluster sampling method in this cross-sectional study. The quality of life was assessed with the Short Form 36 Health Survey (SF-36). Multiple linear regression analysis (stepwise) was performed to examine the factor associated with QOL. Structural equation model (SEM) approach was conducted to test the direct and indirect association between QOL influencing factors with QOL.ResultsThe average QOL score of empty nesters was 63.34 (SD = 17.23). The multiple linear regression revealed that gender, age, education, monthly income, drinking status, exercise frequency, physical examination frequency, attention to daily nutritional health, relationship with a spouse and relationship with children were significant predictors of the empty nester’s QOL (P < 0.05) (R2 = 0.128). SEM showed that behavioral lifestyle had a direct effect on QOL (β = 0.446, P < 0.001). Socio-economic status had an indirect effect (β = 0.288, P < 0.001) on QOL through behavioral lifestyle. The family relationship had an indirect effect (β = 0.115, P < 0.001) on QOL.ConclusionBehavioral lifestyle was the strongest influencing factor in the quality of life among empty nesters, followed by socio-economic status and family relationships. Thus, maintaining a healthy behavioral lifestyle was important to improve the QOL of the empty nesters. Our findings provide a concrete and strong reference for the formulation of targeted intervention strategies.

Spiritual quality of life in family carers of patients with advanced cancer\u2014a cross-sectional study

PurposeCaring affects carers’ psychological and physical health, mortality, and quality of life (QoL) negatively. Lower spiritual QoL is associated with anxiety and depression, but the spiritual dimension is rarely investigated in carers. The present study aimed to explore which patient- and carer-related characteristics were associated with spiritual QoL in carers of patients with advanced cancer.MethodsSecondary analyses were conducted using data from a prospective study investigating integration between oncology and palliative care. Adult patients with advanced cancer and their carers were included, and baseline data considering demographics, clinical characteristics, symptoms, social support, and religious meaning-making were registered. Spiritual QoL was measured using the Functional Assessment of Chronic Illness Therapy - Spiritual well-being (FACIT-Sp-12) questionnaire. Associations to spiritual QoL were explored by bivariate and multivariate regression models.ResultsIn total, 84 carers were included, median age was 62.5 years, 52 (62%) were female, and the average spiritual QoL score was 23.3. In bivariate analyses, higher education, social support, and lower patients’ symptom burden were significantly associated with higher spiritual QoL. The multivariate regression model (n=77) had an explained variance (R2) = 0.34 and showed a significant association for social support, higher education, having children < 18 years living at home, and patient’s age.ConclusionThe study indicates that spiritual QoL in carers were low and were negatively affected by several factors related to both carers and patients. However, there could be other important factors not yet described. Health care professionals should be aware of the known associated factors, as carers who hold these may need extra support.

Evaluation of Gluten-Free Diet Efficacy for Improving Quality of Life of Patients with Celiac Disease

Background: As the only effective treatment of celiac disease (CD) is a lifelong commitment to a gluten-free diet (GFD), this study was designed to evaluate the efficacy of GFD in the quality of life (QOL) of patients with CD to persuade them for strict commitment. Methods: In a cross-sectional study, the QOL of CD patients registered in the celiac society of Khuzestan province was evaluated and compared before and at least one year after commencing GFD using the QOL SF-36 questionnaire. Results: Overall, 200 CD patients (66 males and 134 females) were evaluated. The average age of male and female participants was 26.3 and 30.34 years, respectively (61% between 20 and 60-years-old). After GFD, complaints such as bloating (P = 0.001), abdominal pain (P = 0.001), diarrhea (P = 0.001), nausea (P = 0.001), vomiting (P = 0.03), reflux and regurgitation (P = 0.025), anorexia (P = 0.001), fatigue (P = 0.001), headache (P = 0.008), oral aphthous lesions (P = 0.014), weight loss (P = 0.001), and bone pain (P = 0.005) significantly improved while other symptoms such as muscular pain (P = 0.157), dermatitis (P = 0.083), and numbness (P = 0.317) did not show any major improvement. The average scores of QOL before and after GFD were 0.74 and 3.41, respectively, which demonstrated significant improvement (P = 0.001). This improvement was even seen among cases with sub-optimal compliance (average QOL score 3.28, P = 0.001). Conclusion: A gluten-free diet could significantly improve the quality of life of patients with celiac disease, and they should be encouraged as much as possible to be committed to this regimen.

Quality of life of master’s and doctoral students in health

to assess the quality of life of master's and doctoral students in health. this is a cross-sectional study carried out with 503 master's and doctoral students from the Brazilian Center-West, using the WHOQOL-BREF to analyze their quality of life. Analysis included Cronbach's alpha coefficient, confirmatory factor analysis and bivariate and multivariate analyzes. older age and having a child were associated with higher average quality of life scores, while diagnosis of anxiety/depression, difficulty in managing academic and personal activities and thinking about dropping out of course were associated with lower average scores in quality of life domains (p <0.05). master's and doctoral students have reduced quality of life during the entire training period, mainly in psychological and physical health. The management of academic activities and dropping out of course are the main variables associated with decreased students' quality of life.

Quality of Life Assessment with EQ-5D-3L in a Moroccan Diabetic Population

Diabetes is a chronic metabolic disease that impairs the lifestyle of patients in different physical, mental and social dimensions. This study aims to investigate the determinants of health-related quality of life (HRQoL) in diabetics. A cross-sectional study was conducted on 526 diabetic patients followed in 2019 at the Hygiene Department of the Sidi Othmane district (Casablanca). The data were collected using a questionnaire gathering the demographic, clinical and paraclinical information of patients, as well as a description of health status in the 5 dimensions by the EQ-5D questionnaire. The data was analyzed using SPSS version 23 software. The determinants of quality of life were assessed using the ANOVA test and the Pearson correlation test. The result is considered statistically significant at 0.05. The average quality of life score based on the EQ-5D-3L scale and the VAS analog visual scale was 0.52 ± 0.34 and 55.47 ± 15.50, respectively. Severe problems were observed in anxiety/depression dimensions in 19.20% of patients, while the highest percentages for moderate problems were for the pain/physical discomfort and mobility dimensions (53.80% and 36.90% respectively). The average scores of the EQ-5D-3L and visual analogue scale (VAS) were significantly (P < 0.05) associated with age, gender, education, marital status, professional activity and complications. It follows from this study that the HRQoL of the population of diabetics studied is influenced by many factors, which must be considered in order to achieve better management of diabetes and improve their quality of life.

Calidad de vida y frecuencia de actividad física en adultos mayores de agrupaciones comunitarias, comuna Chillán, Chile

Introducción: El aumento de la población mayor de 60 años a nivel mundial es algo que se evidencia en Chile. Según cifras del último censo de población chilena (2017), existen más de dos millones de personas mayores de 65 años, lo cual representa un 11,4% de los habitantes del país. Por tanto, el envejecimiento activo es algo fundamental para promover la calidad de vida a medida que se envejece, aminorando los efectos negativos del envejecimiento.&#x0D; Objetivo: Conocer la calidad de vida autopercibida y la frecuencia de actividad física grupal de adultos mayores que pertenecen a agrupaciones guiadas por monitoras comunitarias de la comuna de Chillán.&#x0D; Materiales y Método: Se utilizó un cuestionario con tres apartados (Sociodemográficos, de salud y WHOQOL-BREF) aplicado a tres agrupaciones de Adulto Mayor de Chillán y el análisis se hizo por medio de porcentajes, promedio y desviación estándar.&#x0D; Resultados y conclusiones: A mayor edad, mayor puntaje promedio en calidad de vida en 4 de las 5 áreas estudiadas, siendo las personas mayores de 80 años quienes obtuvieron los mayores puntajes promedio. Sin embargo, el área calidad de vida general y física no destaca por los puntajes promedio obtenidos, salvo en las personas que realizan actividad física tres veces por semana.

Quality of life assessment after acute myocardial infarction

Objective: to evaluate the quality of life after acute myocardial infarction, highlighting the differences by sex. Methods: analytical, observational study with 273 patients. For collection, a multidimensional assessment instrument was used for heart attacks. Data collected in a cardiology referral hospital, in which the t Student test was applied for analysis. Results: the majority were male (67.0%),with a mean age of 63.6 years, with a family history of heart attack (64.5%). The average quality of life score was 0.45,with 1.00 being the worst score. Dependence (0.82) and physical activity (0.50) were the worst assessed domains; and side effects (0.27) and diet (0.36), the best. The female gender had the worst averages (0.52, p&lt;0.05), with emphasis on physical activity (0.58), emotion (0.49) and insecurity (0.44). Conclusion: impairments in quality of life were found after myocardial infarction, in which the dependency domain was the most compromised. The female sex had worse scores.

Nivel de Actividad Física en supervivientes de cáncer de mama españolas. Aplicación del HUNT 1-Physical Activity Questionnaire

Objetivo: El objetivo de este estudio fue analizar los niveles de actividad física en supervivientes de cáncer de mama españolas a través de un cuestionario autoadministrado. Asimismo, se estudió la relación entre variables personales y clínicas, variables del entrenamiento y calidad de vida.&#x0D; Método: La presente investigación es de tipo no experimental, descriptiva y transversal. De una muestra significativa (n=386) de mujeres supervivientes de cáncer de mama, se registraron, mediante encuesta autoadministrada: datos antropométricos, sociodemográficos y clínicos; niveles de actividad física mediante cuestionario HUNT1-Physical Activity Questionnaire; y calidad de vida, mediante cuestionario específico para cáncer de mama Functional Assessment Cancer Theraphy-Breast (FACT-B).&#x0D; Resultados: El patrón de entrenamiento más habitual fue de 2-3 veces por semana (40.9%), a intensidad ligera (41.7%) en sesiones de 30-60 minutos (51%). La puntuación media en calidad de vida fue de 93±20 puntos (escala 0-148). El índice de masa corporal resultó influir tanto en nivel de actividad física, como en calidad de vida (p&lt;0.001). Respecto a variables clínicas, se encontró relación entre administración de quimioterapia y frecuencia de entrenamiento (p&lt;0.05); estadio de diagnóstico con puntuación total FACT-B (p&lt;0.05); y existencia de comorbilidades sobre subescala física del test de calidad de vida (p&lt;0.05).&#x0D; Conclusiones: Los resultados indicaron que la mayoría de supervivientes de cáncer de mama españolas no cumplen actualmente los niveles de actividad física recomendados. Del mismo modo sugieren que, aunque el estadio de diagnóstico no parece ser determinante en dicho hábito, sí afecta a su calidad de vida.

Factors Associated with Quality of Life and Glycemic Control in Diabetes Mellitus Type 2 Patients in Sangkha Hospital, Surin Province, Thailand

<!DOCTYPE html> <html> <head> </head> <body> <p style="text-align: justify;"><strong>Objectives: </strong>This study aimed to measure (1) quality of life (QOL) and utility in diabetes mellitus (DM) type 2 patients (2) factors associated the quality of life and (3) factors associated the glycemic control. <strong>Methods:</strong> This study was a cross-sectional study. Samples were DM type 2 patients who attended diabetic outpatient clinic at Sangkha Hospital, Surin province between November 2017 and January 2018. QOL was prospectively assessed using the EQ-5D-5L questionnaire. Data was analyzed by descriptive and binary logistic regression. <strong>Results: </strong>The DM type 2 patients (n=158) were included in this study. The participants had an average QOL score in a high level. There were no factors associated with QOL. The factors associated with glycemic control were education level (OR=2.85; 95%CI: 1.17 &ndash; 6.98) and insulin therapy (OR=3.04; 95%CI: 1.10 &ndash; 8.35). <strong>Conclusion:</strong> There were no factors associated with QOL. Only education level and insulin therapy factors were associated with glycemic control. <p style="text-align: justify;"><strong>Key words: </strong>Diabetes Mellitus, Quality of life, Glycemic control, Factors, EQ-5D-5L. </body> </html>

Gambaran Kualitas Hidup pada Pasien Diabetik Retinopati Berdasarkan Tingkat Keparahan Visus

Diabetic retinopathy (DR) is one of the microvascular complications of diabetes mellitus (DM) which incidence increases with the high prevalence of DM. The presence of these complications will affect quality of life, especially vision-related. The purpose of this study was to determine the quality of life in RD patients assessed using the VFQ-25 and EQ-5D questionnaires, and to determine the of quality of life based on the visual acuity (VA) severity. This study was an observational study in outpatient with diabetic retinopathy during October 2018 – Januari 2019 period, in RSUP dr. Sardjito and RS Mata Dr. YAP, Yogyakarta. The design of this study was cross sectional which observed quality of life and vision. Quality of life was measured by specific for vision instrument (NEI-VFQ-25) and generic instrument (EQ-5D-5L). The number of patients in this study were 100 patients with an average age of 55 years, the most frequent type of RD was 84% proliferative RD. The average quality of life scores in RD patients measured using the VFQ-25 and EQ-5D utility questionnaires were 64.1 ± 16.2 and 0.61 ± 0.24, respectively. Based on VFQ-25, the most affected subscales were driving, dependence, and role difficulties subscale. Meanwhile, domains that have the most problems with the EQ-5D were pain / discomfort and anxiety / depression (78%). The total VFQ-25 score decreased with increasing visual severity, i.e. normal / mild (n = 19) 73.50 ± 15.08; moderate (n = 15) 68.14 ± 15.33; and severe (n = 66) 60.48 ± 15.64. The EQ-5D utility score showed a similar pattern, with scores of 0.66 ± 0.27 (normal / mild); 0.65 ± 0.22 (medium); and 0.59 ± 0.24 (severe); respectively. The higher severity of visual acuity so the quality of life become lower.

MON-506 Assessment of Quality of Life in Persons with Thyroid Cancer and Thyroid Nodules: A Single Center Experience

INTRODUCTION: Despite an excellent prognosis and survival rate, quality of life (QOL) in thyroid cancer is lower than expected. QOL in thyroid cancer survivors is similar to persons with colon and gynecologic cancers, but worse than breast cancer.1 The SF-36 QOL questionnaire has shown to be a valid tool for assessing QOL in thyroid cancer subjects.2 We evaluated QOL in both thyroid nodule and thyroid cancer patients in an institutional cancer registry. METHODS: The Short Form-36 data version 2 (SF-36) QOL data was obtained from single institution prospective bioinformatics thyroid cancer and benign nodule registry. Physical and mental health scores from the SF-36 questionnaire were obtained from both thyroid cancer and nodule patients. Physical and mental QOL responses were scored on a scale from 20-80 and categorized as either “the same or better than the average population,”; “below average,”; or “well below average.” A two sample Wilcoxon rank sum test and a chi-squared test were used to compare QOL between thyroid cancer and nodule subjects, using QOL as a continuous or categorical variable. Univariate descriptive statistics and bivariate analyses were performed using a Wilcoxon Rank Sum and Chi-squared test for categorical QOL data and Kruskal-Wallis for continuous QOL data. RESULTS: We analyzed 321 thyroid cancer and 32 nodule subjects who completed the SF-36 at a single point in time after diagnosis. There was no difference between the groups with regard to sex, age or QOL scores overall. Average age was 43 and 48 years in cancer and nodule groups respectively. Average Physical QOL score was 50.8 (standard deviation SD + 8.8) and 29.6 (SD+ 12.1), respectively (p=0.42). Average Mental QOL score was 48.9 (SD + 9.9) and 48.3 (SD + 8.1) respectively, p=0.16. Physical QOL score was significantly decreased as cancer stage increased when evaluating results as a continuous variable: Stage 1: 51.8 + 8.7; Stage 2: 50.6 +9.5; Stage 3: 48.7 + 7.2; Stage 4: 47.4 + 9.2. Results for mental QOL as a continuous variable by cancer stage showed improvement in reported QOL with increasing cancer stage: Stage 1: 48 (SD+ 9.9); Stage 2: 50.6 (SD + 11.1); Stage 3: 51.1 (SD + 9.13); Stage 4: 53 (SD+ 6.4), p=0.03. CONCLUSIONS: We found no overall difference in physical nor mental QOL between patients with thyroid cancer or benign thyroid nodules. Overall, QOL was in the “same or better than average” for all respondents, but low cancer stage was associated with higher physical and lower mental QOL scores.REFERENCES:1. Barbus, Elena & Peştean, Claudiu & Iulia Larg, Maria & Piciu, Doina. (2016). Quality of life in thyroid cancer patients: A literature review. Clujul Medical. 90. 10.15386/cjmed-7032. Lubitz CC, De Gregorio L, Fingeret AL, et al. Measurement and Variation in Estimation of Quality of Life Effects of Patients Undergoing Treatment for Papillary Thyroid Carcinoma. Thyroid. 2017;27(2):197-206. doi:10.1089/thy.2016.0260

The Influence of Supportive Oncodermatology Interventions on Patient Quality of Life: A Cross-Sectional Survey

Dermatologic adverse events (dAEs) secondary to anticancer treatments reduce patients&rsquo; quality of life (QOL) and result in interruptions in anticancer therapy. Determine if a comprehensive supportive oncodermatology program improves patients&rsquo; QOL scoring. This was a cross-sectional survey of adult cancer patients enrolled in the George Washington University Supportive Oncodermatology Clinic. All patients were above age 18 years and received dermatologic care between May 1, 2017 and November 1, 2019. Fifty-five patents meeting inclusion criteria were invited to complete an online survey with questions adapted from the Dermatology Life Quality Index (DLQI) and Patient Satisfaction Questionnaire (PSQ-18). Survey initiation rate was 61.8% (34/55) and completion rate 88.2% (30/34). Average QOL score prior to treatment was 6.5 (moderate effect on QOL) and 3.8 (small effect) afterwards (P=0.0005; 95% CI -3.9 to -1.). Average satisfaction score was 4.15 &plusmn; 0.7 (satisfied). Impact on treatment adherence earned the lowest score (3.67, neutral to satisfied). Recall bias Conclusion: Enrollment was significantly associated with improved QOL. Dermatologic care also resulted in overall satisfied patient outcomes, although many patients were unsure if these dermatologic interventions aided in anticancer treatment adherence, highlighting the need for evidence-based management strategies for dAEs. J Drugs Dermatol. 2020;19(5): &nbsp;doi:10.36849/JDD.2020.5040.

A nonsurgical approach with repeated orthoptic evaluation is justified for most blow-out fractures

ObjectiveThis study presents the results of an updated clinical protocol for orbital blow-out fractures, with a special emphasis on nonsurgical treatment and orthoptic evaluation of functional improvement. MethodsA two-centre multidisciplinary prospective cohort study was designed to monitor the results of a clinical protocol by assessing ductions, diplopia, globe position, and fracture size. Patients underwent clinical assessment and orthoptic evaluation at first presentation and then at 2 weeks and 3/6/12 months after nonsurgical or surgical treatment. Outcome parameters were field of binocular single vision (BSV), ductions, degree of enophthalmos, a diplopia quality-of-life (QoL) questionnaire, and other sequelae or surgical complications. Results46 of the 58 patients who completed the 3, 6 and/or 12-month follow-up received nonsurgical treatment. There was full recovery without diplopia or enophthalmos (>2 mm) in 45 of the 58 patients. The other 13 patients had limited diplopia, mainly in extreme upward gaze (average BSV 90). Five of those 13 patients did not experience impairment of diplopia in daily life. The average QoL score at the end of follow-up was 97. No patients developed late enophthalmos. ConclusionThis study showed that a high percentage of patients with orbital floor and/or medial wall fracture recovered spontaneously without lasting diplopia or cosmetically disfiguring enophthalmos. The conservative treatment protocol assessed here underlines the importance of orthoptic evaluation of functional parameters.

Results of health-improving treatment of patients with a new COVID-19 coronavirus infection in a phthisiopulmonological sanatorium

The results of sanatorium treatment of 102 patients (aged 18 to 79 years, 30 men and 72 women) who have had a new coronavirus infection (COVID-19) are presented in the article. Materials and methods. A 21-day health im-proving program was developed to restore the functions of external respiration, increase mobility, achieve psych-oemotional stability, and restore patients’ daily activities. Exercise tolerance (6-minute walking test, Borg scale, mMRC scale), hypoxia tolerance (Genchi and Stange func-tional tests), peripheral muscles’ strength (MRC scale), ox-ygen saturation, anxiety and depression intensity (HADS Hospital Anxiety and Depression Scale), quality of life (EQ-5D), and nutritional status were evaluated, as well as in-dicators of external respiratory function of patients upon admission and discharge from the sanatorium. Results.In the result of such therapy clinical and laboratory indi-cators improved (patients rarer complained of weakness (down from 73% to 3.9%), shortness of breath during exercise (from 58 to 14.7%), manifestations of angiodis-tonic syndrome (from 39 to 3%), and ESR level (from 40 to 13.7%). During the 6-minute walk test, there was a sig-nificant increase in the distance traveled compared to the test at admission in all observation groups. 83 out of 90 test subjects (92.2%) co vered a longer distance covered. On average, the distance increased 14% in patients with mild COVID, the average increase was 81 meters, 12% (47 meters) in patients with moderate severity, and 21% (112 meters) in those who had severe infection. Psych-oemotional state evaluated by the Hospital Anxiety and Depression Scale showed a decrease in the average level of anxiety from 4.9 to 3.6, and depression — from 4.3 to 3 points. The average quality of life score (EQ-5D ques-tionnaire) at discharge was 7.3 points compared to 8.9 at admission. Conclusion. The authors demonstrated the effectiveness of the sanatorium-resort care in achieving psychoemotional stability and restoring daily activities in COVID-19 recovalescents

Living with type 1 diabetes mellitus: How does the condition affect children's and adolescents’ quality of life?

ObjectiveOur study aimed to measure the health-related quality of life (QoL) of Tunisian children and adolescents with type 1 diabetes mellitus (T1MD). MethodsThis cross-sectional study included 48 patients aged 3–18 years with T1MD, diagnosed for at least 6 months, and their parents, who underwent outpatient examinations from September to December 2018. The children's QoL was assessed using the PedQL 3.0 Diabetes Module exploring five dimensions: diabetes symptoms, treatment barriers, treatment adherence, worry, and communication problems. Parents shared their perception of their children's QoL through the PedQL 4.0 parents’ report (general health and emotional, social, and scholar functioning). Glycemic control was assessed using the last glycated haemoglobin (HbA1c) values. ResultsThe patients’ average QoL score was 80.52 (±13.61) without significant differences between gender and age. The longer the duration of the disease, the worse the glycemic control. Girls and adolescents seemed to have poorer glycemic control. Boys and adolescents had more difficulties in all aspects of QoL. Parents perceived a worse QoL than that reported by their sons/daughters (72.34±16.42; P=0.006). ConclusionThese findings emphasize the importance of an interdisciplinary, biopsychosocial, and family-centered care approach to patients with T1MD.