Average Quality Of Life Score Research Articles

골관절염 여성노인의 건강관련 삶의 질 영향요인

This research investigates factors impacting the health-related quality of life in elderly women with osteoarthritis. The study surveyed 1,855 participants using National Health and Nutrition Examination Survey data from 2016 to 2020. Statistical analyses, conducted with SPSS/WIN 25, employed T-tests, analysis of variance (ANOVA), cross-analysis, and general linear analysis for descriptive statistics, along with Bonferroni post-hoc tests. Correlations between variables and the quality of life in elderly women with osteoarthritis were determined through correlation coefficients. Additionally, factors influencing the quality of life were analyzed using multiple regression analysis with general linear models. The study revealed significant differences in the quality of life based on demographic such as age, residence, marital status, education level, economic activity, depression, subjective health status, activity limitation, stress perception, smoking, body mass index, exercise, and aerobic activity. Similarly, there were statistically significant differences in the quality of life based on health-related characteristics, including age, residence, marital status, education level, economic activity, depression, subjective health status, activity limitation, stress perception, smoking, body mass index, exercise, and aerobic activity. The average quality of life score for participants was 0.82±0.18, with notable correlations found with age, subjective health status, and stress perception. Factors influencing health-related quality of life included having a spouse, higher household income, engagement in economic activity, lower age, and lower stress levels, as well as higher subjective health status. The model's explanatory power was 36.5%. Based on these findings, the study underscores the necessity for comprehensive and individualized nursing intervention programs.

Quality of life among patients with gastroesophageal reflux disease at Tuyen Quang general Hospital in 2023

Objectives: To assess the quality of life among patients with gastroesophageal reflux disease at Tuyen Quang General Hospital in 2023. Research participants and methods: Cross-sectional descriptive study was conducted with 200 patients from March 2023 to June 2023. The Quality of Life in Reflux and Dyspepsia patients (QOLRAD) was used to interview patients for gastrointestinal examination and endoscopy at Tuyen Quang General Hospital. Results: The average quality of life score among patients was 4.33 - 4.46. In which all fields were at a good level, not too different from the bad level, the average score in the item eating/drinking (4.33), the items of sleep disorders (4.36), the item of emotion (4.39), the item of physical/social (4.39), vitality domain (4.46). Conclusion: The quality of life of patients with gastroesophageal reflux disease at Tuyen Quang General Hospital in 2023 is at a good level in all items.

Serum calcium and magnesium levels and quality of life in environmentally exposed populations in Kazakhstan.

The relationship between the levels of essential elements and various aspects of well-being in environmentally exposed populations still needs to be better understood. The present study aims to investigate the potential connections between serum concentrations of calcium (Ca), magnesium (Mg), and quality of life (QoL) in environmentally exposed populations in Kazakhstan. The present study involved 1881 nominally healthy individuals aged 18-52 years who were permanent residents of Abay, Borodulikha, Ust-Kamenogorsk, Kurchum, Uralsk, Aksay, and Berezovka settlements. These settlements were selected to represent different types of environmental exposure: radioactive fallout from the Semipalatinsk Nuclear Test Site (SNTS), non-ferrous metallurgy, and the condensate gas field, compared to environmentally unexposed territories. The Russian version of the SF-36 questionnaire was used to assess the participants' quality of life. Serum Ca levels were measured using colorimetry with O-cresolphthalein, and serum Mg concentrations were measured using colorimetry with xylidyl blue. Both elevated and decreased serum Ca levels were more frequently observed in the environmentally exposed populations. The prevalence of hypermagnesemia was highest among residents near the condensate gas field. Environmentally exposed populations residing near the SNTS and in Ust-Kamenogorsk exhibited lower scores in some QoL domains. In contrast, people near the condensate gas field showed comparable or even higher QoL scores than the control population. Only serum Mg demonstrated a significant association with the average QoL scores, while Ca did not show such an association. These findings have important implications for public health interventions.

Quality of Life of Patients Receiving Warfarin Therapy at a Tertiary Care Centre in Indonesia Using DASS (Duke Anticoagulation Satisfaction Scale).

This study aimed to examine the quality of life of patients receiving warfarin therapy at Dr. Hasan Sadikin Central General Hospital, and its relationship with demographic factors. The procedures started with the submission of a study permit, followed by validation of the Duke Anticoagulation Satisfaction Scale (DASS) questionnaire. In addition, the validated questionnaire was completed by the participants, and significant variables were analyzed using the chi-square method for multivariate analysis. The results showed that the questionnaire was valid and could be used for further analyses. Among the 88 selected participants, 52 and 36 had scoring categories <56.266 and 56.266 ≤ x ≤ 143.734, respectively, with no patients having a scoring category > 143.734. In addition, participants with low education and aged ≥ 52 years were 4.916 and 3.161 times more at risk of having quality of life score of 56.266 ≤ x ≤ 143.734, respectively. Based on the results, the average quality of life score of patients was 59.66. Participants with low educational levels and those aged ≥ 52 years were at a higher risk of having quality of life score of 56.266 ≤ x ≤ 143.734. In summary, a lower quality of life score was linked to increased comfort and satisfaction among patients receiving warfarin treatment. Additionally, these patients experienced fewer feelings of limitations and inconveniences related to their treatment plans.

The Neuropsychological and Emotional Profile of Adults with Parasomnia: A Case Series

Although parasomnias are nocturnal phenomena occurring during sleep or during arousals from sleep, there is increasing evidence that they are associated with daytime dysfunction as well. However, systematic studies in this field are scarce. The aim of the current case series was to investigate the sleep–wake, neuropsychological and emotional profiles of patients with parasomnias. Thirty patients with parasomnia (13 NREM, 17 REM) and 30 healthy subjects matched for age, sex and educational status were included. All participants underwent comprehensive neuropsychological, cognitive and behavioral evaluation. We found that parasomnia patients scored higher in all neuropsychological, emotional, sleep–wake and quality of life scales compared to healthy subjects. The presence of a parasomnia was associated with major impact on daytime functioning across several domains with increased levels of fatigue (FSS &gt; 4) in 56%, sleepiness (ESS &gt; 10) in 47%, depressive symptoms (BDI &gt; 20) in 17%, anxiety (PSWQ &gt; 52) in 17%, anger expression out (STAXI A &gt; 16) in 27% and anger expression in (STAXI B &gt; 16) in 23%, as well as a reduced average quality of life score (RAND derived from SF-36). Sleep–wake disturbances were significantly correlated with QoL scores. In the intergroup analysis between REM/NREM, we found that the REM group had worse cognitive performance and lower levels of fatigue/energy compared to NREM patients. These findings suggest that parasomnia is associated with difficulties in several aspects of daytime functioning (cognitive, affective/emotional and physical) and, therefore, parasomnia diagnostic workup should not be limited only to nocturnal phenomena.

Satisfaction and quality of life of nurses satisfaction and quality of life of nurses in a public hospital during the COVID-19 pandemic

Objective: To evaluate the satisfaction and quality of life (QL) of nurses working in a public hospital. Method: This is a cross-sectional study developed during COVID-19 with nurses who had 6 months of work, between October 2020 and February 2021, at a State Oncological Reference Hospital in São Luís-MA. A questionnaire was applied on sociodemographic characteristics and the WHOQOL-bref and Employee Satisfaction Index (ESI) instruments. A normality test was performed followed by the Spearman correlation coefficient with a significance level of 5%. Results: 71 nurses participated in the survey and the average QL scores in all domains are regular (3.64) and employee satisfaction, in all domains, is low (2.50). A weak positive correlation was observed in all domains of the WHOQOL-bref and in the autonomy of the ESI (physical - r=0.482; psychological - r=0.285; social - r=0.318; and environment - r=0.251), while weak negative correlation was observed between the professional status and the psychological (r=-0.312) and the social (r=-0.374) domain and work and environment requirements (r=-0.295). Conclusion and implications for practice: The nurses showed regular and low QL, satisfied and knowing the reasons helps managers to propose interventions to reduce the QL benefit and to improve the care provided.

Quality of life change seen after Diverted Mini Gastric Bypass Surgery in Obese Population: Retrospective research analysis

Background: With an increase in life expectancy all over the globe, morbid obesity and obesity-related diseases negatively impact the overall quality of life (QoL).&#x0D; Aim: The study aimed to assess the QoL post-Diverted Mini Gastric Bypass (dMGB), focusing on weight loss achieved, comorbidity resolution, and change in QoL after the surgery. Setting: Single private institute, India&#x0D; Methods : Data from patients who underwent a laparoscopic primary dMGB from August 2020 to August 2021 by one surgeon were retrospectively analyzed. The patients were followed up at 3,6,9, and 12 months from the surgery date. Data were assessed using the Bariatric Analysis and Reporting Outcome System- II (BAROS- II) form based on three major areas: percentage weight loss, comorbidity resolution, and QoL. The variation in QoL was assessed using the Moorehead Ardelt QoL questionnaire, which addresses self-esteem, physical activity, social gathering, and sexual life.&#x0D; Results: Forty-one patients were included in the final analysis. The average age and pre-operative body mass index (BMI) was 45.5 yrs. and 44.5 kg/m2, respectively. The cohort had 60.9% of males and 39.1% females. The pre-operative average total QoL score was 0.65 ± 0.2. At 12 months, the average BMI and average total QoL were 28.03 kg/m2 and 5.35 ± 0.3, respectively, p&lt;0.001.&#x0D; Conclusion: At one year, the dMGB surgery effectively improves the overall QoL.&#x0D; Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 759-767

The Impact of Sexual Violence on Quality of Life and Mental Wellbeing in Transgender and Gender-Diverse Adolescents and Young Adults: A Mixed-Methods Approach.

Transgender (trans) and gender-diverse (GD) adolescents and young adults have remained largely invisible in health research. Previous research shows worse outcomes in health indicators for trans and GD people, compared to cisgender controls. Research on the impact of sexual violence focuses on mainly cisgender female adult victims. This study assessed the impact of sexual violence on the quality of life (QoL) and mental wellbeing (GHQ-12) among trans and GD adolescents and young adults, while taking into account the possible role of gender nonconformity in sexual violence and mental wellbeing. An online, anonymous survey and interviews/focus groups were conducted between October 2021 and May 2022 in Belgium. Multiple analyses of covariance (ANCOVAs) were used to assess the associations between sexual violence, mental wellbeing, and gender nonconformity, while controlling for different background variables (gender identity, sexual orientation, age, economic vulnerability, etc.). The interviews and focus groups were used to validate associations between variables that were hypothesized as important. The quantitative sample consisted of 110 respondents between 15 and 25 years old, with 30 trans respondents (27.3%) and 80 GD respondents (72.7%). A total of 73.6% reported experiences with sexual violence over the past two years (n = 81). The mean QoL score was 5.3/10, and the mean GHQ-12 score was 6.6/12. Sexual violence was not significantly associated with QoL (p = 0.157) and only marginally significantly associated with GHQ-12 (p = 0.05). Changing one's physical appearance to conform to gender norms, out of fear of getting attacked, discriminated against, or harassed was significantly associated with QoL (p = 0.009) and GHQ-12 (p = 0.041). The association between sexual violence and changing one's physical appearance to conform to gender norms was analyzed, to assess a possible mediation effect of sexual violence on mental wellbeing. No significant association was found (p = 0.261). However, the interviews suggest that sexual violence is associated with changing one's physical appearance, but this association is not limited to only trans and GD victims of sexual violence. Non-victims also adjust their appearance, out of fear of future sexual victimization. Together with the high proportion of sexual violence, as well as the lower average QoL and higher average GHQ-12 scores among trans and GD adolescents and young adults, compared to general population statistics, this highlights the need for policy makers to create more inclusive environments.

Quality of life in elderly patients with venous thromboembolism assessed using patient-reported outcome measures

BackgroundWe aimed to evaluate the quality of life (QoL), using patient-reported outcome measures (PROMs), in elderly patients with venous thromboembolism (VTE) and to explore whether VTE complications (recurrence, bleeding, or postthrombotic syndrome) had an impact on later QoL. MethodsWe used data from the SWIss venous Thromboembolism COhort of older patients(SWITCO65+), a prospective multicenter cohort of patients aged ≥65 years with acute, symptomatic VTE. Primary outcome was changes in QoL up to 24 months, assessed using generic (36-Item Short-Form Health Survey), with physical (PCS) and mental component score (MCS), and disease-specific (Venous Insufficiency Epidemiological and Economic Study [VEINES]-QoL, [VEINES-Sym], and Pulmonary Embolism QoL) PROMs. PROM scores ranged from 0 to 100 points, higher scores indicating a better QoL. Longitudinal latent class analysis was used to group patients with similar PCS trajectories. Repeated-measures linear regression analyses were used to assess effects of VTE complications on changes in QoL scores. ResultsIn 923 patients (median age, 75; male, 54%), 140 (15%) patients died, 97 (11%) experienced recurrent VTE, and 106 (12%) major bleeding during follow-up. Compared with patients with higher PCS trajectories, patients with lower PCS trajectories were more likely to be older, female, sicker, and less physically active. On average, generic and disease-specific QoL scores improved over time (+11% in PCS, +3% in MCS, +6% in VEINES QoL, and +16% in Pulmonary Embolism QoL at 3 months). VTE complications were always associated with significantly lower QoL scores (for VTE recurrence: PCS adjusted difference -2.57, 95% CI, −4.47 to −0.67). ConclusionAlthough QoL following VTE tended to improve over time, patients with VTE-related complications had lower QoL than patients without complications.

Knowledge of and behaviors toward a gluten-free diet among women at a health sciences university

PurposeGluten-free diets have gained popularity worldwide. However, little information is available regarding the knowledge of, and behaviors toward, this diet among adults in KSA. This study was aimed at addressing this knowledge gap. MethodsA cross-sectional survey was conducted in 352 women at a health sciences university in KSA. ResultsEleven percent of participants had followed a gluten-free diet at least once, 70% of whom had voluntarily tried this diet without a confirmed medical diagnosis. The main source of information regarding this diet was the internet and social media. Additionally, followers of this diet had moderate knowledge of gluten and its products yet higher knowledge than that of non-followers (65% vs 56%, P = .0055). Following a GFD was associated with an age of 25 years or older, higher education, and being employed. Although 56% of participants reported following this diet 75% or more of the time, the average calculated adherence score was low. Although 95% of the followers indicated changes in their lifestyle and social life, 71% felt better after following this diet, and only 2.6% felt worse. This self-reported results were confirmed by a calculated average quality of life score of 1.3, indicating a good quality of life after following this diet. ConclusionThis study indicated moderate knowledge and low adherence to a gluten-free diet among followers. This finding may be attributable to the high percentage of followers without a confirmed medical condition, or to the social and lifestyle changes faced by followers of GFDs. Educational programs should be introduced to the public to increase awareness of gluten-free foods and diets.

Self-rated health and quality of life in female sex workers with substance use disorders in Tehran, Iran

BackgroundWhile self-rated health (SRH) and quality of life (QoL) has been associated with substance use disorders (SUDs) in sex-working populations, little is known about this association in Iran. This study aimed to assess QoL and SRH in Iranian female sex workers (FSWs) in Tehran.MethodFSWs were recruited using convenience sampling methods from substance abuse treatment centers in Tehran that exclusively provided services for women. Participants completed an interviewer-administered demographic questionnaire in Persian and the Iranian version of the Short Form Health Survey (SF-36). Descriptive analyses, means and standard deviations; frequency and percentages, t-test and one-way ANOVA, and Chi-square tests were utilized to analyze the data.ResultsThe mean age among 161 participants clinically diagnosed with SUD was 34.09 years (SD 7.97; range: 18–57). The total mean QoL score was 41.03 (SD: 12.92). The highest and lowest mean scores were observed in the physical functioning (52.23) and role emotional (26.64) dimensions, respectively. Significant differences (p < 0.05) in QoL were observed according to education and marital status, and the average QoL score was lower in women who reported permanent marriages and women who were illiterate. The average score of QoL was significantly higher in employed women. Overall, 51.6% of the women rated their health as sub-optimal, with divorced participants and women who were illiterate more likely to rate their health as sub-optimal (p < 0.05).ConclusionResults emphasize the need for mental, physical, and sexual health screening and gender-specific interventions to improve QoL in this population. Further investigation may elucidate the consequences of poor SRH and QoL on SUD treatment adherence, sexual risk behavior, and morbidity and mortality in FSWs.

Russian localization and validation of the BRACE QUESTIONNAIRE

BACKGROUND:According to the literature, the Greek questionnaire on the study of the quality of life of children and adolescents undergoing brace treatment (BRACE questionnaire, abbreviated as BrQ) is informative and reliable, which is confirmed by its validation in different countries. This necessitates the creation ofanadopted Russian version and its validation.&#x0D; AIM:To perform Russian localization and validation of the Greek questionnaire on the study of the quality of life of children and adolescents undergoing brace treatment.&#x0D; MATERIALS AND METHODS:Russian localization and validation of the Russian version of the questionnaire on braces (Ru-BrQ) was carried out in several stages: direct and reverse translations, examination of the questionnaire, formation ofapreliminary version, pilot testing of 104 patients with idiopathic scoliosis on brace treatment, development of the final version, reliability study using the evaluation of Cronbachs alpha criterion and intraclass correlation coefficient (ICC), and provision of the final version.&#x0D; RESULTS:According to the indicators of the overall Ru-BrQ score, 0% of patients scored at the floor and ceiling levels. The average quality of life scores according to Ru-BrQ and in the retest were 72 9.2 and 72.4 9.0 points, respectively. According to the ICC indicator, domains such as general health, self-esteem and aesthetics, vitality, and social functioning showed excellent reliability (0.9). Physical functioning and school activity demonstrated good reliability(0.750.9).Emotional functioning and body pain demonstrated moderate reliability (0.50.75). The Cronbachs alpha coefficient showed that except for the domains emotional functioning and body pain, where good internal consistency was determined (0.8), all other domains confirmed excellent internal consistency (0.9). The Pearson correlation coefficient (index 0.67) revealedanoticeable correlation between Ru-BrQ and the Russian version of SRS-22.&#x0D; CONCLUSIONS:The Russian version isareliable questionnaire for the study of the quality of life of children and adolescents undergoing brace treatment, comparable with the original Greek version of BrQ, and can be recommended for use in practical and scientific activities to assess the effect ofatorso brace on the quality of life in children and adolescents.

Thực trạng và một số yếu tố liên quan đến chất lượng cuộc sống của người mắc lao phổi điều trị ngoại trú tại Trung tâm Y tế quận Gò Vấp, Thành phố Hồ Chí Minh, năm 2022

Objectives: Describe the current situation and some factors related to the quality of life of people with pulmonary tuberculosis undergoing outpatient treatment at Go Vap District Health Center in 2022. Subjects and methods: A cross-sectional study was carried out from December 2021 to June 2022, using the SF-36 questionnaire version 2.0 to assess the quality of life of 140 people. TB patients aged 18 years or older were treated as outpatients at the Go Vap District Health Center. The multivariable linear regression model was applied with descriptive and univariate analysis. Results: The average score of 8 aspects of quality of life was from 47.1 to 77.3 points, with the lowest being general health and the highest being physical functioning. The average score for physical health was 65.4 points; mental health was 64.3 points. The average quality of life score was 65.0 points. Unmarried people with pulmonary tuberculosis had an average quality of life score 9.55 points higher (CI95%: 2.36 - 16.73) than the married group. Conclusion: The quality of life of people with pulmonary tuberculosis was average and was related to marital status. Keywords: Quality of life, SF-36, pulmonary tuberculosis.

Transcutaneous tibial neurostimulation and Solifenacin in urgent incontinence of postmenopausal women.

Symptoms of overactive bladder syndrome (OAB), including urinary incontinence, affect a person's quality of life and cause many personal, social and economic problems. Patients were randomly divided into three groups and received transcutaneous tibial nerve stimulation (cTTNS) with fixed parameters or with variable parameters (vTTNS) and Solifenacin drug. The main outcomes including quality of life questionnaire and OAB score and other secondary outcomes were evaluated before and after treatment for 6 weeks. ANOVA test did not show any significant difference between the three groups in quality of life score (p=0.672), OAB symptom score (p=0.159) and incontinence severity (p=0.422). The t-test demonstrated that the post treatment average quality of life score, OAB score, and incontinence severity were significantly different when compared with before treatment in all three groups (p < 0.05). All three methods were effective in treating symptoms of OAB. However, based on the clinical symptoms, cTTNS is recommended as a preferred and acceptable and safe strategy for the treatment of OAB in women over 50 years old.

Transitional Care Model in Germany: Findings from an economic analysis of a randomized controlled trial

IntroductionThe statutory discharge management system in German hospitals does not provide adequate transitional care for geriatric patients. The American Transitional Care Model (TCM), where a qualified professional supports the patient for a period before, during, and after discharge, could help to address this problem. In this study, we compared both approaches from an economic perspective. Our research questions were: (1) How do treatment costs per person differ when geriatric patients are supported according to the TCM compared with routine discharge management? (2) What are the intervention costs? MethodsThe present economic analysis was part of a randomized controlled trial conducted at a hospital in Germany. In this study, geriatric patients in the intervention group received care according to TCM and those in the control group received routine care. We obtained data from the hospital and a health insurance company. In a cost-cost analysis, we compared the treatment costs per patient incurred in both study groups. In cases where higher costs occurred in the intervention group, we also conducted a cost-utility analysis, using the 12-Item Short Form Survey questionnaire to collect quality of life data for the Quality Adjusted Life Years calculation. Intervention costs were calculated on the basis of staff salaries, working hours, and the cost of acquiring the necessary equipment. ResultsThe intervention group consisted of 109 geriatric patients, the control group of 119. The average quality of life score was slightly higher in the intervention group, but the difference was not significant. On average, the intervention group was less expensive. However, for individual cost types (e.g., rehabilitation), the intervention group incurred higher costs than the control group. The differences between the study groups were not significant for all cost types (p > 0.05). Intervention costs were estimated to be approximately 800 euros per patient. DiscussionThe TCM approach leads to savings. However, the amount of savings will depend on intervention costs, which vary in practice. After outlier exclusion, an unfavorable incremental cost-effectiveness ratio is observed for the TCM approach. ConclusionFrom an economic perspective, TCM in its present form provides no additional value to patient care compared with routine discharge management. However, we see an urgent need to optimize the existing discharge management system to ensure better transitional care for those affected. Therefore, we recommend that different TCM components should be tested in further studies to address the questions that could not be clarified in the present study.

Translation, adaptation and validation of the Chrononutrition Profile – Questionnaire (CP-Q) in Brazilian Portuguese

ABSTRACT Chrononutrition is a science that studies the relationship between mealtimes and sleep/wake habits. However, these behaviors are not evaluated by a single questionnaire. Therefore, this study aimed to translate and culturally adapt the Chrononutrition Profile – Questionnaire (CP-Q) into Portuguese and validate the Brazilian version. The translation and cultural adaptation process consisted of: translation; synthesis of translations; backtranslation; expert committee and pre-test. The validation was performed with 635 participants (32.4 ± 11.2 years) who answered the CPQ-Brazil and Pittsburgh Sleep Quality Index (PSQI); Munich Chronotype Questionnaire (MCTQ); Night Eating questionnaire; Quality of life and health index (SF-36) and 24 h-recall. The participants were mostly female, single, from the northeastern region, a eutrophic profile, and average quality of life score of 55.8 ± 17.9. Moderate to strong correlations were observed in the sleep/wake schedules between CPQ-Brazil, PSQI and MCTQ, both for work/study days and free days. The correlations between largest meal, skipping breakfast, eating window, nocturnal latency, and last eating event with the same variables in the 24 h-recall showed moderate to strong positive correlations. The translation, adaptation, validation and reproducibility of the CP-Q generates a valid and reliable questionnaire to assess the sleep/wake and eating habits in the Brazilian population.

The Relationship Between Sleep Quality and Quality of Life Among Postmenopausal Women

Background: With increased life expectancy and changes in lifespan, now women spend more years after menopause. Women with menopausal symptoms may experience a lower quality of life (QoL) and complain about poor sleep quality. This study aimed to examine the relationship between QoL and sleep quality in postmenopausal women. Methods: This research was a predictive correlational study. The study sample was 200 postmenopausal women referred to the healthcare centers affiliated with Mashhad University of Medical Sciences in Mashhad City, Iran, in 2021. The subjects were selected through multistage cluster sampling. To assess the quality of sleep and life quality, the Pittsburgh Sleep Quality Index (PSQI) and Menopause-Specific QoL questionnaire (MENQOL) were used. The obtained data were analyzed by the Pearson correlation coefficient and multiple linear regression in SPSS software, version 21. The significance level was set at P&lt;0.05. Results: The mean±SD age of the subjects was 53.92±6.13 years. Their mean±SD scores of sleep quality and QoL were 48.62±21.98 and 4.93±2.74, respectively, and 37% of women had sleep disorders. The multiple determination coefficient for the linear regression model was equal to 0.35, and there was a significant direct relationship between sleep quality and QoL (b=3.72, 95% CI =2.70-4.74, P&lt;0.001). So for each unit change in sleep quality, the average QoL score increased by 3.72 units. Conclusion: Considering the relationship between sleep quality and QoL in postmenopausal women, it is recommended that these women use appropriate methods to improve sleep quality. Also, health professionals should keep this issue in mind when examining the health status of this group of women.

Clinical analysis of percutaneous kyphoplasty for spinal metastases in older adults with comorbidities

IntroductionWe aimed to investigate the clinical outcomes of percutaneous kyphoplasty (PKP) for spinal metastases in older adult patients with comorbidities. Materials and MethodsNinety-two older adults (age ≥ 60 years) with spinal metastases who underwent 148 PKP procedures were retrospectively analyzed. Tokuhashi scores, Tomita scores, age-adjusted Charlson Comorbidity Index (aCCI) scores, and American Society of Anesthesiologists (ASA) scores were evaluated before the procedure. The visual analog scale (VAS), Oswestry Disability Index (ODI), vertebral body height (VBH), and quality of life (QoL) were used to assess the efficacy of the procedure. Clinical safety was evaluated based on periprocedural complications. ResultsTokuhashi scores and Tomita scores were 7.3 ± 4.0 and 5.8 ± 2.1, respectively. Excluding cancer-related factors, twelve patients (13.0%) had aCCI scores ≥4. Forty-three patients (46.7%) had ASA status ≥ III. Compared to preoperative status, average VAS scores, ODI scores, VBH variation, and QoL scores significantly improved at each follow-up examination point after PKP (p < 0.001). No major complications occurred, nor was there decompensation of comorbidities in the perioperative period. Seventeen segments (11.5%) of twelve patients (13.0%) suffered bone cement leakage. Among them, one patient suffered intercostal neuralgia cured by steroid injection, and the other patient suffered hyperesthesia, which disappeared after taking gabapentin (0.3 g, bid) for five weeks. Another minor complication of local hematoma occurred in one patient, which spontaneously resolved without surgical intervention. DiscussionPKP serves as a safe approach to provide significant pain relief, vertebral body height restoration, and QoL improvements for spinal metastases in older adults, independent of underlying disease.

Association of pain and quality of life among middle-aged and older adults of India

BackgroundIndia is passing through a phase of demographic and epidemiological transition where ageing and chronic morbidities are being more common. Though studies have examined the prevalence and risk factors of pain and other chronic morbidities, nationally representative research examining the association of pain and quality of life (QoL) is limited in India. This study examines the association between pain and QoL among middle-aged and older adults in India.MethodsThis study uses the data from wave 1 of the Longitudinal Ageing Study in India (LASI) conducted in 2017-18. This study is restricted to 58,328 individuals from all states (except Sikkim), aged 45 years and above. The quality of life is measured in 6 domains (physical, psychological, social, environment, general health and life satisfaction) with 21 variables that range from 0 to 100. The principal component analysis was used to generate a composite score of QoL and the multiple linear regression was used to show the association between pain and quality of life.ResultsIt is estimated that approximately 37% of Indian middle-aged and older populations were often troubled with pain. Pain prevalence increase with age and is more common among older adults aged 75 + years (43.37%; 95% CI, 40.95–45.80), and female (41.38%; 95% CI, 39.36–43.39). The average QoL score among those with pain was 81.6 compared to 85.2 among those without pain. QoL was lower among elderly age 75 and above, females, rural residents and illiterates. Controlling for socio-demographic factors, pain reduces the QoL by 2.57 points (β= −2.57; 95% CI, −3.02 - −2.11).ConclusionPain reduces the quality of life among middle-aged adults and older adults in India. This evidence could potentially help the policymakers to consider pain as a significant determinant of quality of life in India.

Exploring the Association Between Resilience and Quality of Life Among Glaucoma Patients: Sleep Disturbance as a Mediating Factor.

Patients with glaucoma may experience many symptoms such as blindness, which seriously affect their quality of life (QoL). Resilience is playing a vital role in enhancing the QoL and well-being of patients with chronic diseases. In addition, sleep disturbance is common in patients with glaucoma, leading to a decline in their QoL. However, there is a dearth of research on whether sleep disturbance plays a mediating role between resilience and QoL among glaucoma patients. The aim of this study is to explore the role of sleep disturbance in the relationship between resilience and QoL among glaucoma patients. From July to December 2019, a cross-sectional survey was conducted on 215 glaucoma patients in an ophthalmic hospital in Liaoning Province. Hierarchical multiple regression (HMR) analyses and structural equation modeling (SEM) were conducted to examine the factors related to QoL and to test the hypothesis that sleep disturbance mediates the relationship between resilience and QoL among glaucoma patients. The average QoL score among glaucoma patients was 43.85 ± 14.97 as reported by the Glaucoma Quality of Life-15 (GQL-15) scale, where a higher scores indicating a poorer QoL. Resilience was found to be linked with a lower QoL score (P < 0.01), while sleep disturbance was associated with a higher QoL score (P < 0.01). When sleep disturbance was included in the model as partial mediator, the path coefficients for the association between resilience and QoL score was significantly decreased (a*b = -0.1, BCa95% CI: -0.154∼-0.045). Findings of this study reflected that QoL among glaucoma patients in China was poor. Resilience was found to be an important positive factor, which could result in the improvement of QoL. Furthermore, sleep disturbance mediated the relationship between resilience and QoL among patients with glaucoma, thereby reducing the positive impact of resilience on QoL in glaucoma patients. Efforts to improve QoL among glaucoma patients may benefit from interventions that enhance the levels of resilience and promote healthy sleep.