Average Eye Research Articles

Eye yoga exercises to reduce eye fatigue syndrome during online learning

Background: Eye fatigue syndrome increases as students use computers and smartphones during online learning. Interventions to reduce the eye fatigue syndrome and avoid the severity of its symptoms need to be performed with appropriate and easy-to-practice techniques.Objective: This study aims to determine effects of eye yoga exercises on eye fatigue syndrome in students during online learning. Methods: This study applied one group pretest-post-test design involving 30 students from Universitas ‘Aisyiyah Bandung, West Java Province, Indonesia. Its samples were collected by using a proportional stratified random sampling. The eye yoga exercises were practiced four times for one week and had to begin 30 minutes after the end of online learning. The eye fatigue syndrome was measured using the Computer Vision Syndrome Questionnaire (CVS-Q). The difference in the intervention effect was calculated by using the Wilcoxon Signed-Rank Test. Results: This study revealed that the yoga eye exercises significantly affected the eye fatigue syndrome (Z= -4.636; p-value < 0.05). The average eye fatigue score decreased; the eye fatigue score before the intervention was 14.40 ± 9.17, and it decreased to 9.17 ± 4.88 after the eye yoga exercise intervention was given.Conclusion: Eye yoga exercises can reduce the level of eye fatigue syndrome in students who are learning by using electronic devices. The exercises can be performed independently to reduce this syndrome when working with a computer or smartphone. This intervention can be a standard for preventing the syndrome in educational institutions by incorporating eye yoga exercises after learning activities, particularly in online learning.

Evaluating Silvering Stages in European Eels: A Study on Biological and Morphometric Variations in the Asi River, Türkiye

The European eel (Anguilla anguilla) undergoes significant morphological and physiological changes during its transition from the yellow to the silver stage, which are critical for its long-distance spawning migration. This study aimed to investigate these changes in European eels from the Asi River, located in Hatay, Türkiye, during their silvering process. A total of 96 eels were sampled in February 2019, and various morphometric measurements, including total length, body weight, eye dimensions and height, and pectoral fin lengths, were taken. Liver and gonad weights were also measured to assess the hepatosomatic index (HSI). The length–weight relationship for silver eels was described by the equation, W = 0.0072 × L2.732, with silver-stage eels showing a higher growth rate compared to yellow-stage eels, which had a relationship of W = 0.0184 × L2.397. The average total length of silver eels (431.2 ± 16.7 mm) was significantly greater than that of yellow eels (382.4 ± 11.9 mm). Additionally, pectoral fin length was significantly longer in silver eels (20.8 ± 1.1 mm) compared to yellow eels (14.8 ± 0.9 mm). The hepatosomatic index (HSI) for silver eels was also found to be higher than for yellow eels, indicating increased liver size as an adaptation for energy storage during migration. Eye height, a key indicator of silvering, showed a substantial increase during the transition, with silver-stage eels having an average eye height of 5.3 ± 0.2 mm compared to 4.2 ± 0.1 mm in yellow-stage eels.

EDOF – HOW DOES IT WORK?

EDOF is the name of a new category of intraocular lenses that are a kind of compromise between traditional monofocal and trifocal IOLs. Monofocal IOLs allow you to have good vision at one distance with high quality. Multifocal, on the contrary, give sufficient visual acuity at various distances, but are characterized by the presence of a large number of dysphotopsias. Intraocular lenses with extended focus provide greater independence from glasses than monofocals while maintaining high quality vision.Objective: to discuss the available information on the principles of EDOF imaging by lenses and the dependence of the state of the wavefront of the artiphakic eye on the combination of spherical corneal aberrations and IOLs.The wavefront of the eye is formed by several structural elements, the main of which are the cornea and the lens (artificial lens). The study of aberrations of the human eye is in the field of refractive surgery. Attempts to use aberrations in cataract surgery began with the creation of aspherical IOLs. The latter were intended to correct spherical corneal aberrations and were aimed at improving the characteristics of the wavefront. The development and use of aspherical IOLs were based on data on the state of the cornea of the average eye and gave a conditional effect. The new generation of IOLs based on the creation of a certain number and type of spherical aberrations is designed to modify (deform) the wavefront of the artifakic eye and expand its optical capabilities while maintaining a low number of dysphotopsias. This, in a way, revolutionary change in trends brings cataract surgery even closer to refractive surgery.According to the authors, for the fullest use of the capabilities of IOLs from the EDOF category, it is necessary to apply the principles and experience of refractive surgery in terms of studying the characteristics of the operated eye and correlating them with the parameters planned for IOL implantation.

Virtual reality interview with feedback framework for situational practice of gaze among autistic adults

BackgroundAutistic individuals commonly seek employment; however, only a small fraction are in the workforce. In part, this might be due to mismatches between their social patterns of attention and gaze, and society’s normative expectations during interviews. MethodTo help mitigate such disadvantages through a solo situational practice tool, we present a framework that consists of a virtual reality (VR) based job interview simulation and a coaching component. Employing data visualization, video modeling, and VR role-play of the targeted behavior, the coaching support could be done in a self-deliverable practice manner. A participatory design session with two autistic design partners was important in the co-creation of the feedback methods, making them easier to understand, and including positive reinforcement. ResultsFourteen autistic individuals used the VR job interview simulation tool. Eleven received the gaze analysis and support stage and participated in a second VR simulation session. Preliminary results were positive, in that participant scores on average eye contact duration, average time without eye contact, and percentage of eye contact while listening and while speaking generally approached the corresponding medians of the non-autistic reference dataset. Participants were surveyed about the utility of the tool after the second feedback session and two months later. All survey respondents perceived the tool to be useful and the provided feedback to be helpful in daily social interactions. ConclusionsThis study provides insights towards the development of a VR job interview simulation and feedback framework that can enable solo situational practice of gaze and common interview questions.

Influencing factors for pediatric eye disorders and health related quality of life: a cross-sectional study in Shanghai, China.

Myopia, strabismus, and ptosis are common pediatric eye diseases, which have a negative impact on children and adolescents in terms of visual function, mental health, and health-related quality of life (HRQoL). Therefore, this study focused on those pediatric eye diseases by analyzing their risk factors and HRQoL for the comprehensive management of myopia, strabismus, and ptosis. A total of 363 participants (2-18 years old) were included in this study for risk factors analysis of myopia, strabismus, and ptosis. We collected demographic characteristics, lifestyle habits and eye care habits of these children and analyzed them by using univariable and multivariable logistic regression. In addition, we applied the Chinese version of Pediatric Quality of Life Inventory-Version 4.0 (PedsQL 4.0) to assess HRQoL in 256 children with strabismus and ptosis. Univariable and multivariable linear regression models were applied to evaluate potential influencing factors of HRQoL. Of all the participants, 140 had myopia, 127 had strabismus, and 145 had ptosis. Based on the multivariable logistic regression analysis model, we found that the history of parental myopia and daily average near-distance eye usage time were risk factors for myopia, and increased body mass index (BMI) was identified as a risk factor for strabismus and ptosis. Individuals with ptosis possessed decreased HRQoL. The multivariable linear regression model suggested that daily average near-distance eye usage time, light intensity during visual tasks, and daily average sleep duration had potential influences on HRQoL. This is the first study to assess the risk factors and HRQoL of myopia, strabismus, and ptosis together. We identified risk factors for these common pediatric eye diseases to help doctors, parents, and teachers better manage them. Our study discovered that children with eye disorders exhibit a notably diminished HRQoL. Consequently, it emphasizes the necessity for increased social attention and mental health assistance for these children.

The Correlation Between Lighting Intensity, Eye Fatigue, Occupational Stress, and Sleep Quality in the Control Room Operators of Abadan Refinery

Background: The control room is a critical work environment where optimal performance is essential to minimize errors. Lighting is one of the key environmental factors influencing the performance of control room operators. Inadequate sleep quality and job stress also significantly impact job performance. Poor sleep quality, eye fatigue, inappropriate lighting, and occupational stress can lead to errors and decreased accuracy in work. Objectives: The present study aims to determine the correlation between lighting intensity, eye fatigue, occupational stress, and sleep quality among control room operators at the Abadan Refinery. The study was conducted in 2022. Methods: This cross-sectional descriptive-analytical study was conducted on 190 control room operators at the Abadan Refinery in 2022. A lux meter device was used to evaluate the intensity of lighting. Standard Pittsburgh sleep quality, eye fatigue, and Occupational Stress questionnaires were also administered. The results were analyzed using SPSS software. Results: The average light intensity of the work surface was 347.95 ± 147.34 lux. The mean and standard deviation of job stress score and sleep quality were 155.42 ± 9.18 and 9.38 ± 1.62, respectively. The average eye fatigue score was 5.09 ± 0.821 in people without glasses and 4.47 ± 0.828 in people with glasses. A significant correlation was found between brightness intensity and visual fatigue (ρ = 0.201, P = 0.029). The correlation between eye fatigue and sleep quality score was also significant (ρ = 0.225, P = 0.002). However, no significant correlation was observed between lighting intensity and sleep quality (ρ = - 0.005, P = 0.946). The correlation between the overall score of occupational stress and sleep quality was statistically significant (r = - 0.148, P = 0.042). Conclusions: The results showed a significant correlation between lighting intensity and the factors of sleep quality and eye fatigue. Additionally, there was a significant correlation between eye fatigue and sleep quality, as well as between occupational stress and sleep quality. Therefore, it is suggested that planning to minimize job stress, and improve lighting and sleep quality for gas refinery control room personnel should be designed and implemented by the authorities.

Weighted single-step genome-wide association study to reveal new candidate genes for productive traits of Landrace pig in Korea.

The objective of this study was to identify genomic regions and candidate genes associated with productive traits using a total of 37,099 productive records and 6,683 single nucleotide polymorphism (SNP) data obtained from five Great-Grand-Parents (GGP) farms in Landrace. The estimated of heritabilities for days to 105 kg (AGE), average daily gain (ADG), backfat thickness (BF), and eye muscle area (EMA) were 0.49, 0.49, 0.56, and 0.23, respectively. We identified a genetic window that explained 2.05%-2.34% for each trait of the total genetic variance. We observed a clear partitioning of the four traits into two groups, and the most significant genomic region for AGE and ADG were located on the Sus scrofa chromosome (SSC) 1, while BF and EMA were located on SSC 2. We conducted Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), which revealed results in three biological processes, four cellular component, three molecular function, and six KEGG pathway. Significant SNPs can be used as markers for quantitative trait loci (QTL) investigation and genomic selection (GS) for productive traits in Landrace pig.

Occupational eye lens dose among nuclear medicine workers in a tertiary hospital in Saudi Arabia

Background: Exposure to ionizing radiation remains a major concern in nuclear medicine, especially given the possible health risks posed to medical personnel. Additionally, since the occupational eye dose limit was lowered in 2011 to an equivalent dose of 20 mSv/yr, new implications have extended to roles within nuclear medicine units. The goal of this investigation was to determine the current occupational radiation eye doses for nuclear medicine employees. Methods: A 5 yr retrospective assessment was performed on staff members involved in all nuclear medicine imaging from different categories. Optically Stimulated Luminescence (OSL) badges were used to measure occupational dose. The H-lens values were calculated for each staff member during this period. Results: Significant differences were observed between individual staff members in terms of H-lens values. They were significantly higher among hot lab technicians than among NIC (p < 0.001) and NM (p < 0.0001) technicians. Conclusions: Although none of the participants exceeded the eye dose limit for ionizing radiation exposure, there was significant variation in exposure across various roles and expertise. The annual average eye dose ranged from 0.2 mSv to 2.9 mSv, which is within the advised dose limit.

Evaluation of Selected Biometric Parameters in Cataract Patients-A Comparison between Argos® and IOLMaster 700®: Two Swept-Source Optical Coherence Tomography-Based Biometers.

Background and Objectives: To compare the biometry of eyes obtained with two swept-source optical coherence tomography-based biometers-Argos (A), using an individual refractive index, and IOLMaster 700 (IM), using an equivalent refractive index-for all structures. Materials and Methods: The biometry of 105 eyes of 105 patients before cataracts were analyzed in this study. Parameters such as axial length (AL), anterior chamber depth (ACD), and lens thickness (LT) were compared from both devices. According to the axial length measurements, patients were divided into three groups, as follows: group 1-short eyes (AL < 22.5 mm), group 2-average eyes (22.5 ≤ AL ≤ 26.0 mm), and group 3-long eyes (AL > 26.0 mm). Results: The correlation coefficiency among all compared parameters varies from R = 0.92 to R = 1.00, indicating excellent reliability of IM and A. A statistical significance in axial length was indicated in the group of short eyes (n = 26)-mean AL (A) 21.90 mm (±0.59 mm) vs. AL (IM) 21.8 mm ± (0.61 mm) (p < 0.001)-and in the group of long eyes (n = 5)-mean AL (A) 27.95 mm (±2.62 mm) vs. mean AL (IM) 28.10 mm (±2.64) (p < 0.05). In the group of average eyes (n = 74), outcomes were similar-mean AL (A) 23.56 mm (±0.70 mm) vs. mean AL (IM) 23,56 mm (±0.71 mm) (p > 0.05). The anterior chamber depth measurements were higher when obtained with Argos than with IOLMaster 700-mean ACD (A) 3.06 mm (±0.48 mm) vs. mean ACD (IM) 2.92 mm (±0.46) p < 0.001. There was no statistical significance in mean LT-mean LT (A) 4.75 mm (±0.46 mm) vs. mean LT (IM) 4.72 mm (±0.44 mm) (p = 0.054). The biometry of one eye with dense cataracts could be measured only with Argos, using the Enhanced Retinal Visualization mode. Conclusions: Axial length measurements from both devices were different in the groups of short and long eyes, but were comparable in the group of average eyes. The anterior chamber depth values obtained with Argos were higher than the measurements acquired with IOLMaster 700. These differences may be particularly important when selecting IOLs for patients with extreme AL values.

Infrared Thermography in Assessment of Facial Temperature of Racing Sighthound-Type Dogs in Different Environmental Conditions.

The aim of the study was to assess the usefulness of IRT measurements of selected regions of interest (ROI), i.e., the eyeball and the nose of whippet dogs, before and after coursing competitions taking place in various environmental conditions, thereby enabling the assessment of well-being and the level of heat stress. The research was carried out over two different periods with different thermal humidity indexes (THIs). In the first period, the THI was 59.27 (Run 1), while in the second period, the THI was 63.77 (Run 2). The experimental subjects comprised 111 sighthound-type dogs-whippets-that were photographed with a thermal imaging camera to determine their eye temperature (ET) and nose temperature (NT). The average minimum and maximum eye temperatures were statistically lower after running in both measurements. Increased minimum and maximum nose temperatures were also demonstrated after both runs. The nasal temperature values were statistically higher for Run 2, for which the THI was higher, compared to Run 1. Eyeball temperature may be a marker of thermoregulation ability, regardless of the ambient temperature. The value of ETmax decreased on average by 2.23 °C and 0.4 °C, while NTmax increased uniformly by 2 °C after both runs. A correlation was found between the IRT measurements and physiological indicators.

Optical and clinical simulated performance of a new refractive extended depth of focus intraocular lens

sObjectivesThe purpose of this study is to evaluate the optical and expected clinical performance of a new refractive Extended Depth of Focus (EDF) intraocular lens (IOL), TECNIS PureSee™ IOL, designed to maintain a monofocal-like dysphotopsia profile.MethodsSimulated visual acuity (sVA) with varying defocus was calculated using the area under the Modulation Transfer Function measured in an average eye model and from computer simulations in eye models with corneal higher-order aberrations. Tolerance to defocus was evaluated using computer simulations of the uncorrected distance sVA under defocus. To evaluate the dysphotopsia profile, halo pictures obtained using an IOL-telescope, as well as simulated images in a realistic eye model under defocus were assessed. The results of the refractive EDF, TECNIS PureSee™ IOL, were compared to those of a diffractive EDF, TECNIS Symfony™ IOL, of the same platform.ResultsThe refractive EDF IOL provides similar range of vision to the diffractive EDF IOL with the same distance, and similar intermediate and near sVA. The refractive EDF IOL provides the same tolerance to hyperopia as the diffractive EDF but more tolerance to myopia. Halo pictures and simulations showed that the refractive EDF provides comparable dysphotopsia profile to the monofocal IOL and better than the diffractive EDF.ConclusionsThe results of this preclinical study in clinically relevant conditions show that the new refractive EDF IOL is expected to provide similar range of vision to the diffractive IOL of the same platform and higher tolerance to refractive errors. The refractive EDF provides a dysphotopsia profile that is better than the diffractive EDF and comparable to that of the monofocal IOL, also in the presence of residual refractive errors.

Functional Anatomy of Split Compound Eyes of the Whirligig Beetles Dineutus mellyi (Coleoptera: Gyrinidae).

The functional anatomy of the split compound eyes of whirligig beetles Dineutus mellyi (Coleoptera: Gyrinidae) was examined by advanced microscopy and microcomputed tomography. We report the first 3D visualization and analysis of the split compound eyes. On average, the dorsal and ventral eyes contain 1913 ± 44.5 facets and 3099 ± 86.2 facets, respectively. The larger area of ventral eyes ensures a higher field of vision underwater. The ommatidium of the split compound eyes is made up of laminated cornea lenses that offer protection against mechanical injuries, bullet-shaped crystalline cones that guide light to the photoreceptive regions, and screening pigments that ensure directional light passage. The photoreceptive elements, made up of eight retinular cells, exhibit a tri-tiered rhabdom structure, including the upper distal rhabdom, a clear zone that ensures maximum light passage, and an enlarged lower distal rhabdom that ensures optimal photon capture.

Correction Method for Optical Scaling of Fundoscopy Images: Development, Validation, and First Implementation.

Although fundus photography is extensively used in ophthalmology, refraction prevents accurate distance measurement on fundus images, as the resulting scaling differs between subjects due to varying ocular anatomy. We propose a PARaxial Optical fundus Scaling (PAROS) method to correct for this variation using commonly available clinical data. The complete optics of the eye and fundus camera were modeled using ray transfer matrix formalism to obtain fundus image magnification. The subject's ocular geometry was personalized using biometry, spherical equivalent of refraction (RSE), keratometry, and/or corneal topography data. The PAROS method was validated using 41 different eye phantoms and subsequently evaluated in 44 healthy phakic subjects (of whom 11 had phakic intraocular lenses [pIOLs]), 29 pseudophakic subjects, and 21 patients with uveal melanoma. Validation of the PAROS method showed small differences between model and actual image magnification (maximum 3.3%). Relative to the average eye, large differences in fundus magnification were observed, ranging from 0.79 to 1.48. Magnification was strongly inversely related to RSE (R2=0.67). In phakic subjects, magnification was directly proportional to axial length (R2=0.34). The inverse relation was seen in pIOL (R2=0.79) and pseudophakic (R2=0.12) subjects. RSE was a strong contributor to magnification differences (1%-83%). As this effect is not considered in the commonly used Bennett-Littmann method, statistically significant differences up to 40% (mean absolute 9%) were observed compared to the PAROS method (P<0.001). The significant differences in fundus image scaling observed among subjects can be accurately accounted for with the PAROS method, enabling more accurate quantitative assessment of fundus photography.

Limitation the use of Laptops when Online Learning Reduce the Eye Fatique of Private Junior High School Students in Denpasar

The emergence of eye fatique in junior high school students during the online learning process is caused by the length of time the eyes stare at the laptop for a long time. In addition, the presence of more sophisticated learning media, the position of the laptop is very important and has a main function in supporting the online learning process. From a preliminary study conducted on 10 students from a private junior high school in Denpasar, it was found that 50% of students experienced complaints of dizziness, 50% glare and 20% sore eyes. With the above background, a study with the same subject design was conducted involving 25 students with an age range of 13-14 years. The study was conducted for 3 consecutive days, namely on Tuesday, Wednesday and Thursday by measuring eye fatigue using an eye fatigue questionnaire. The data were analyzed using the t-paired test at a significance level of p = 0.005. After using the laptop was limited according to the radiation exposure time from the appropriate laptop, the eye sight distance to the monitor screen was set 50-100 cm and interspersed with pauses or rest periods then the average eye fatigue in students before the improvement of 22.54 can be reduced to 5.25 or about 71%. Conclusion: From the research, it was concluded that limiting the duration of using laptops during online learning can reduce students' eye fatigue

Driver Drowsiness Detection using Machine Learning Approach

Driver fatigue is a major cause of traffic accidents. The number of deaths and injuries increases every year around the world. Traffic accidents can be reduced by detecting driver fatigue. This article describes machine learning for sleep detection. Face detection is used to detect the driver's eye area and use this as a reference for eye tracking in subsequent frames. Finally, visual images are used to detect sleep and a warning system is created. This method is divided into three stages: face detection, eye detection, and fatigue detection. Image processing is used to recognize the driver's face and then extract the image of the driver's eyes to detect fatigue. HAAR face detection algorithm outputs the image and then adjusts face detection based on the output. CHT is then used to track the eyes of the visible face. Check the eyes using EAR (Early Evaluation). The proposed system was tested using the proposed system on a Raspberry pi 3 Model B with 1 GB RAM using Logitech HD Webcam C270. According to some video tests, average eye contact and tracking accuracy can reach 95.0%. Therefore, it is a cheaper and better solution for a tired driver to ask to find the road immediately.

Mapping of fundus photography to 3D imaging for ocular radiotherapy

Aims/Purpose: Ocular Proton Therapy (OPT) is one of the main treatments for uveal melanoma. Full inclusion of fundus images in the treatment planning is currently hindered by the refraction of the eye's optical elements. In this study we developed and evaluated a method to correct for these effects, with the final aim of enabling an OPT‐planning which spares more of the healthy retina.Methods: A paraxial method to correct for the scaling fundus photographs of the central retina was developed using ray transform matrices. This method was subsequently extended to the full retina using ray tracing simulations in Zemax OpticStudio through the ZOSPy library [1]. These methods were evaluated in 33 eyes in which the corneal topography, lens location, thickness and curvature, and retinal shape were personalized. The resulting scaling of the fundus images was finally compared with the method currently used in OPT planning (EYEPLAN).Results: For the central retina the magnification relative to the average eye ranged from 0.79 to 1.50 and was approximately inversely proportional to the eye's spherical equivalent. For the peripheral retina, a nodal point‐based mapping provided no systematic errors and the least variation between subjects (up to 2.5 degrees at 70degrees eccentricity). This method proved a significant improvement compared to the currently used method which had a systematic error of approximately 21 degrees as it incorrectly modelled the refractive effect of the eye's optics.Conclusions: Using the nodal point as a reference point, fundus images can be accurately mapped to 3D imaging, enabling the inclusion of optical information in OPT planning.

Analisis Distribusi Dosis Berkas Foton pada Kanker Nasofaring dengan Teknik Intensity Modulated Radiation Therapy (IMRT) menggunakan Pesawat Linear Accelerator di Sub Instalasi Radioterapi RSUP Prof. Dr. I.G.N.G. Ngoerah

Analysis for the distribution of photon beam doses in nasopharyngeal cancer has been carried out with the Intensity Modulated Radiation Therapy (IMRT) technique at the Sub-Installation of RSUP Prof. Dr. I.G.N.G. Ngoerah. Calculations were carried out by analyzing the values of the Homogeneity Index (HI) and Conformity Index (CI) as well as radiation dose in Organs a t Risk (OAR). Data from 20 nasopharyngeal cancer patients were used, and a 6 MV energy photon beam with a total dose of 7000 cGy was used, using seven beams of irradiation direction. The data used are radiation doses of 2%, 50%, and 98%, target volume and 95%, and doses at OAR. These data are obtained from the Dose Volume Histogram (DVH) curve in the Treatment Planning System (TPS) process. The results obtained were the average dose distribution on cancer targets in the form of HI and CI values for 20 patients, namely the average HI value of 0.1231±0.0244, while the average CI value was 0.9856±0.022 which, when compared to ICRU report 83 of 2010 HI and CI values were still within the allowable standard limits. The average dose distribution in OAR for 20 patients was the mean spinal cord (4683.9±216.47) cGy, the average right eye (3909.7±605.45) cGy, the average left eye (3683.885±659.89) cGy, the average right optic nerve (4149.01±1099.68) cGy, the average left optic nerve (4174.355±1219.96) cGy, the average right lens (746.29±149.85) cGy, and the average left lens (753.03±144.32) cGy, all average values obtained by OAR are still within the allowable limits. Keywords: nasopharyngeal cancer, 6 MV, IMRT, homogeneity index, conformity index, organ at risk

Examining how information presentation methods and a chatbot impact the use and effectiveness of electronic health record patient portals: An exploratory study

ObjectivesExamining information presentation strategies that may facilitate patient education through patient portals is important for effective health education. MethodsA randomized exploratory study evaluated information presentation (text or videos) and a chatbot in patient education and examined several performance and outcome variables (e.g., search duration, Decisional Conflict Scale, and eye-tracking measures), along with a simple descriptive qualitative content analysis of the transcript of chatbot. ResultsOf the 92 participants, those within the text conditions (n = 46, p < 0.001), had chatbot experiences (B =−74.85, p = 0.046), knew someone with IBD (B =−98.66, p = 0.039), and preferred to engage in medical decision-making (B =102.32, p = 0.006) were more efficient in information-searching. Participants with videos spent longer in information-searching (mean=666.5 (SD=171.6) VS 480.3 (SD=159.5) seconds, p < 0.001) but felt more informed (mean score=18.8 (SD=17.6) VS 27.4 (SD=18.9), p = 0.027). The participants’ average eye fixation duration with videos was significantly higher (mean= 473.8 ms, SD=52.9, p < 0.001). ConclusionsParticipants in video conditions were less efficient but more effective in information seeking. Exploring the trade-offs between efficiency and effectiveness for user interface designs is important to appropriately deliver education within patient portals. Practice implicationsThis study suggests that user interface designs and chatbots impact health information’s efficiency and effectiveness.

Metabolomics Analysis Provides Novel Insights into the Difference in Meat Quality between Different Pig Breeds.

The Chuanzang black (CB) pig is a new crossbred between Chinese local breeds and modern breeds. Here, we investigated the growth performance, plasma indexes, carcass traits, and meat quality characteristics of conventional DLY (Duroc × Landrace × Yorkshire) crossbreed and CB pigs. The LC-MS/MS-based metabolomics of pork from DLY and CB pigs, as well as the relationship between the changes in the metabolic spectrum and meat quality, were analyzed. In this study, CB pigs presented lower final body weight, average daily gain, carcass weight, and eye muscle area than DLY pigs (p ˂ 0.05). Conversely, the ratio of feed to gain, marbling score, and meat color score of longissimus dorsi (LD) were higher in CB than DLY pigs (p ˂ 0.05). Moreover, psoas major (PM) showed a higher meat color score and a lower cooking loss in CB than DLY pigs (p ˂ 0.05). Interestingly, CB pigs showed lower myofiber diameter and area but higher myofiber density than DLY pigs (p ˂ 0.05). Furthermore, the mRNA expression levels of MyHC I, PPARδ, MEF2C, NFATC1, and AMPKα1 were higher in CB than DLY pigs (p ˂ 0.05). Importantly, a total of 753 metabolites were detected in the two tissues (e.g., psoas major and longissimus dorsi) of CB and DLY pigs, of which the difference in metabolite profiles in psoas major between crossbreeds was greater than that in longissimus dorsi. Specifically, palmitic acid, stearic acid, L-aspartic acid, corticosterone, and tetrahydrocorticosterone were the most relevant metabolites of psoas major meat quality, and tetrahydrocorticosterone, L-Palmitoylcarnitine, arachidic acid, erucic acid, and 13Z,16Z-docosadienoic acid in longissimus dorsi meat were positively correlated with meat quality. The most significantly enriched KEGG pathways in psoas major and longissimus dorsi pork were galactose metabolism and purine metabolism, respectively. These results not only indicated improved meat quality in CB pigs as compared to DLY pigs but may also assist in rational target selection for nutritional intervention or genetic breeding in the swine industry.

Primary Transscleral Diode Laser Cyclophotocoagulation for Management of Glaucoma in Nanophthalmic Eyes.

The aim of this study was to assess the efficacy and safety of double-row transscleral cyclophotocoagulation in controlling intraocular pressure in patients with secondary angle closure glaucoma due to nanophthalmos, not being controlled by medical therapy. A prospective case series study that included 13 eyes of 8 patients diagnosed with secondary angle closure glaucoma due to nanophthalmos at the Giza Eye Subspeciality Center, treated by 24 cyclodiode applications in a double-row technique. Success was defined as complete success by control of intraocular pressure <21mmHg without medication and qualified success in which control of pressure <21mmHg achieved with 1 or 2 medications. The average reduction in intraocular pressure at 3 months was 57.3±20.14% and at 6 months 44.5±32%, with an average eye drop intake of 1.3±0.8 drops. There was a significant reduction of intraocular pressure at 6 months compared with the preprocedure pressure ( P =0.01). Complete success achieved in 3 eyes, pressure controlled without any medication, and qualified success in 9 eyes. Transscleral cyclophotocoagulation is a safe and effective primary therapy for managing glaucoma in nanophthalmic eyes.