Normal Anxiety Levels Research Articles

PECULIARITIES OF EXPRESSING ANXIETY AND FEAR IN THE TRAINING AND COMPETITIVE PROCESS OF YOUNG JUDOKAS

Examining the level of anxiety, we can conclude that the average level of anxiety was recorded in the training process, which in this situation can have a negative impact on the further results of the training process. As the level of emotional stress rises during the competition, the efficiency of the athlete’s activity first quickly increases, and then his growth slows down, starting from a certain individual level. Studying the manifestations of emotions in athletes, conducting a study of fear and anxiety, we came to the conclusion that high emotional stress in sports practice has a negative impact on athletes.

ПСИХОЛОГІЧНІ ОСОБЛИВОСТІ ВЗАЄМОЗВ'ЯЗКУ ЖИТТЄСТІЙКОСТІ ТА ТРИВОЖНОСТІ

The article describes the hardiness of the individual. It is represented by a set of attitudes, skills that provide courage, courage, bravery, and strategies that should turn stressors into opportunities for growth. Three main components are revealed: risk involvement, control and acceptance and their functions. It is determined that a person who has a high level of hardiness has a stable psychological and physical health, well adapted to the social space. It is noted that hardiness exists on three levels: psychophysiological (optimal responses to stress), socio-psychological (effective self-regulation) and personal-semantic (meaningfulness and positive worldview). Also, the essence of personality anxiety is characterized, it is presented as a certain emotional state of a person that arises under conditions of probable surprises in the case of postponement, delay of pleasant situations, and while waiting for trouble. It was found that anxiety can be both situational and personal. It is emphasized that situational anxiety arises from a stressful state or stimulus that affects a person at a particular time, and personal anxiety, in turn, is a personality trait that characterizes a person as prone to constant anxiety. Also identified and characterized are anxiety, neurotic, and moral anxiety. It is emphasized that anxiety can be a factor in mental problems, neuroses and fears. The article analyzes the results of an empirical study on the peculiarities of the manifestation of hardiness and anxiety of students. In particular, it was found that the average level of hardiness prevails among young people (45%) and the average level of anxiety, which tends to be high (33%). There is also a direct correlation between students' resilience and anxiety. It was proved that the subjects who had a low level of hardiness had a high level of anxiety, and the subjects who, in turn, had a high and medium level of hardiness, had a low or medium level of anxiety, which tended to low.

Апробация методики «Задача на беглость проспективного мышления» в русскоязычной выборке

The goal of this preliminary study was to carry out adaption of the Future Thinking Task (FTT) in 4 comparison groups: women without addictions and with normative anxiety and depression levels (n = 30); women with high levels of anxiety (n = 20); men without addictions and with normative anxiety and depression levels (n = 32); men with addiction (n = 23). We expected to find a number of specific differences between groups in terms of their FT parameters (thematic content and FT fluency) using the framework of FTT. Methods: FTT; Hospital Anxiety and Depression Scale; phonemic verbal fluency task (PVF); AUDIT, the alcohol use screening test; content analysis; mathematical methods. Results and conclusions: We found differences between the control male sample and the clinical group of addicts, as well as between the community female samples with high and normal anxiety levels. Women with high anxiety had a greater number of negative future events. Patients with addictions had a reduced number of positive future events and total events across different time periods, and especially in the short term. The decrease in the number of positive short-term events may be explained by a greater self-destructive potential of addicts. The results reflect recognized specific features of addicted and anxious people’s FT. The findings on the correlations between PVF and FT fluency which were found in the male groups exclusively need additional verification. The data obtained allow us to infer that the Russian version of FTT can be used for research purposes.

Characteristics of student response to pandemic in cross-cultural context

Of the work is a cross-cultural analysis of the characteristics of student response in a pandemic situation. The sample consisted of students of NSMU and the Kazakh National University. Al-Farabi in the amount of 37 people aged 20 to 23; The battery of psychological methods was compiled by Spielberger and Khanina; Mississippi Post-Traumatic Stress Disorder Scale (civil version) and PSM-25 Psychological Stress Scale. 52.7% of respondents showed an average level of stress, 47.3% - a low level, which indicates insufficient psychological adaptation to psychological stress. High rates of personal and situational anxiety were diagnosed in 67.57% of cases; the average level of reactive anxiety - in 29.73% of cases and personal - in 27.03% of respondents. The majority of respondents showed average levels of post-traumatic stress reactions (50%, n=37), while a low level of post-traumatic stress reactions occurs in 11 (14.87%) people, a low level - in 17 (22.97%) people and increased - in 9 (12.16%) people. Stress level indicators tend to have significant differences: the frequency of occurrence of average stress indicators in the sample of students from Kazakhstan is higher (75.6%) compared to Russian students (24.32%) (p<0.05). Cross-cultural differences in the level of emotional response of students in a pandemic situation were revealed.

PSYCHOLOGICAL WELL-BEING OF PREGNANT WOMEN DURING THE WAR

Armed conflicts are an extremely stressful event and have not only socioeconomic problems, but also negative consequences for the social and mental of people’s health. Nowadays, due to the war, almost all the population of Ukraine was in stress conditions. But, in our opinion, the conditions of war will have a particularly negative impact on the level of anxiety and psychological pregnant women well-being. Since the state of pregnancy itself, even under favorable external conditions, causes serious changes not only to the body of women, but also in its way of life and perception of the world and makes the woman more vulnerable and more susceptible to the influence of the environment. And the results of this stress can have consequences for two generations – both for mother and child. Therefore, our research is devoted to influence of anxiety on psychological state and subjective well-being of pregnant women. In order to study the variables selected by theoretical analysis, the following methods to measure the level of anxiety, the level of psychological well-being and determine the type of psychological component of gestational dominance (PCGD) were used. The Spielberger-Hanin test was used to measure anxiety. Psychological wellbeing was studied using the C. Ryff questionnaire adapted by S.V. Karskanova. To determine the type of pregnancy experience, the V.I. Dobryakov pregnant woman attitude test was used, revealing the types of PCGD: optimal, hypogestognostic, euphoric, anxious, depressive. As to the level of anxiety, the non-pregnant group showed a moderate reactive anxiety level, whereas in the pregnant group it was high. Both groups showed moderate (average) levels of personal anxiety. Measurement on the reactive anxiety self-assessment scale revealed statistically significant differences between groups (p &lt; 0,01). The level of psychological well-being of pregnant women was 8,02% lower than the level of psychological well-being of non-pregnant women. The difference between the groups was statistically significant (p &lt; 0,05), which confirms our hypothesis that pregnancy in the conditions of war negatively affects the level of psychological well-being.

Profile of sport competition anxiety trait and psychological coping skills among secondary school athletes in Enugu State, South East Nigeria

Background: The study investigated the profile of sport competition anxiety trait and psychological coping skills (PCS) among secondary school athletes in Enugu State, South East Nigeria. Material/Methods: A total number of 420 secondary school athletes participated in a cross-sectional study. The profile of sport competition anxiety trait and psychological coping skills of the participants were measured using a 46-item questionnaire consisting of three socio-demographic factors as part I, a 15-item Sport Competition Anxiety Test (SCAT) as part II and a 28-item Athletic Coping Skills Inventory (ACSI) as part III. Mean, standard deviation and linear regressions were used for analyses. Results: The findings revealed that secondary school athletes had an average level of anxiety (mean±SD=20.79±3.776), and greater strength on psychological coping skills (mean±SD=49.92±19.20) while participating in sport competitions. Coachability, Goal setting and mental preparation, and Freedom from worry had significant association (p&lt;.05) with athletes’ Sport Competition Anxiety. Conclusions: This research proves that increase in psychological coping skills leads to increase in athletes’ competition anxiety while participating in sport. However, sport psychologists, Physical Education teachers, games masters/mistresses and coaches in secondary schools need to acquire psychological skills through specialized seminar or expertise training so as to enable athletes to cope with sport anxiety.

Psychological Health and its Correlates during the COVID-19 Pandemic in Pakistan: A Survey of Undergraduate Students

With the outbreak of a global pandemic, people were faced with many difficulties such as financial and health issues, including psychological problems. There was a sharp rise in mental health issues as people were advised to observe social distancing resulting in social isolation. The present study examined three measures of psychological distress among the undergraduate student population: depression, anxiety, and stress. It also sought to study differences in academic years and gender on measures of psychological distress. A convenient and snowball sample of 1032 undergraduate students, aged between 17 and 25 years (M=21.81, SD = 1.99), filled out a survey. DASS – 21 was used to collect data on depression, anxiety, and stress among students. Descriptive statistics showed mild to normal levels of stress (M = 9.64), anxiety (M = 8.17) and depression (M = 9.05). Independent t-tests revealed significantly higher levels of psychological distress among women compared to men. Further, a one-way ANOVA and post hoc analyses showed that only juniors had significantly higher levels of stress compared to freshmen. Factors such as social support and religion have been discussed as possible explanations for lower levels of psychological distress in the overall student population. This research highlights resilience among students and future research should focus on investigating the factors which can help in dealing with difficult situations.

Relationships among pulmonary function, anxiety and depression in mild asthma: An exploratory study

In a secondary analysis of data from a prior study, we calculated the relationships among depression (PHQ-8), anxiety (GAD-7), and measures of asthma in 69 steroid-naïve patients with mild and moderate symptomatic asthma. Average levels of pulmonary function, depression and anxiety tended to be in the normal range, and asthma tended to be well controlled (Asthma Control Test). Nevertheless, PHQ-8 scores were significantly correlated with forced oscillation (FO) measures of airway reactance (AX) and resistance at a low frequency of stimulation (Rrs5 Hz). GAD-7 scores also were significantly related to Rrs5 Hz. Exploratory analyses in Supplementary data provide no evidence for vagal mediation of the association. Further research is necessary to discover mechanisms for the associations found here. Future studies might examine the utility of assessing and treating mild anxiety and depression in mild to moderate asthma.

Maternal Mental Health following Ultrasonographic Detection of Fetal Structural Anomaly in the Midst of the COVID-19 Pandemic.

Prenatal ultrasonographic detection of fetal structural anomaly may adversely affect maternal mental health throughout pregnancy, particularly in the current COVID-19 pandemic. This study aims to prospectively assess maternal stress, anxiety, and depression following ultrasonographic detection of fetal structural anomaly from diagnosis until delivery during the COVID-19 pandemic. A total of 141 pregnant women at a tertiary hospital who underwent detailed scans between 16 and 24 gestational weeks were included and categorized into the study (anomaly finding, n = 65) and comparison (normal finding, n = 76) groups. Self-administered questionnaires of 10-item Perceived Stress Scale (PSS-10) and Hospital Anxiety and Depression Scale (HADS) were used to assess maternal stress, anxiety, and depression at prior detection (T1), two-to-four weeks post-detection (T2), one-to-two weeks prior to delivery (T3), and one-to-two weeks post-delivery (T4). Repeated measures of analysis of variance (ANOVA) were conducted to assess time-, between-group, and time–group interaction effect. In general, maternal stress improved, but anxiety worsened, while depression persisted, over the time from T1 to T4. The average maternal stress and anxiety levels were significantly higher among groups with fetal anomaly. The maternal stress and anxiety level were significantly affected within one-to-two weeks post-detection of fetal structural anomaly. In conclusion, maternal mental health parameters were affected differently during the COVID-19 pandemic, with higher vulnerability of stress and anxiety among pregnant women with fetal structural anomaly particularly within one-to-two weeks post-detection.

Prevalence and influencing factors of anxiety and depression symptoms among surgical nurses during COVID-19 pandemic: A large-scale cross-sectional study.

AimTo evaluate the prevalence and influencing factors of anxiety and depression symptoms in surgical nurses during the COVID‐19 epidemic in Anhui, China.MethodsA cross‐sectional, multic'entre quantitative study was conducted among surgical nurses in Anhui province. SAS, SDS and SSRS scales were used for the investigation. Data were collected between 3 March 2020 to 19 March 2020.ResultsA total of 3,492 surgical nurses completed the survey. The average level of anxiety and depression of surgical nurses were higher than that of the Chinese norm. Levels of social support for surgical nurses were significantly negatively associated with the degree of anxiety and depression. Fertility status, participation in care for COVID‐19 patients, likelihood of being infected with COVID‐19 and social support were significantly influencing surgical nurses’ anxiety degree. Similarly, these characteristics were significantly associated with the odds of depression symptoms in surgical nurses.ConclusionThese findings suggest that targeted psychological interventions to promote mental health of surgical nurses need to be immediately implemented.

Kesehatan Mental dan Strategi Koping Mahasiswa Keperawatan pada Masa Pandemi COVID-19

This study aims to assess stress levels, mental health, depression and anxiety in nursing students during the COVID-19 pandemic. The method used in this study is a literature study on the PubMed, ScienceDirect, Scilit, Proquest and Google Scholar databases. The results show that the COVID-19 disease outbreak has become a threat to global health. Its spread which continues to this day, greatly affects the education sector. Students carry out coping strategies to avoid factors that can reduce their mental health conditions. In conclusion, students have a higher stress level than female students. However, in general, the respondents had normal levels of depression, normal levels of anxiety, normal stress levels and did not have clinically significant insomnia.&#x0D; Keywords: COVID-19, Mental Health, Nursing Students, Coping Strategies, Literature Study

Mental Health and Prenatal Bonding in Pregnant Women During the COVID-19 Pandemic: Evidence for Heightened Risk Compared With a Prepandemic Sample

We compared 572 pregnant women (319 first-time mothers) surveyed in spring 2020, during the first wave of COVID-19 lockdowns in the United States, with 99 pregnant women (all first-time mothers) surveyed before the pandemic (2014–2020). Compared with the prepandemic sample, women assessed during the pandemic showed elevated depression, anxiety, and stress and weaker prenatal bonding to their infants. These findings remained significant when restricting the pandemic sample to first-time mothers only and held after controlling for race/ethnicity, education, and pregnancy stage. Average levels of depression and anxiety within the pandemic group exceeded clinically significant thresholds, and women who estimated that the pandemic had more negatively affected their social relationships reported higher distress. However, pandemic-related changes to social contact outside the household were inconsistently associated with mental health and with some positive outcomes (fewer depressive symptoms, stronger prenatal bonding). Given that prenatal stress may compromise maternal and child well-being, the pandemic may have long-term implications for population health.

Psychological responses and associated factors during the initial stage of the coronavirus disease (COVID-19) epidemic among the adult population in Poland - a cross-sectional study

IntroductionThe study aimed to assess the emotional state, the occurrence of symptoms of depression, anxiety, and stress, as well as the quality of life of adults living in Poland during the first weeks of the COVID-19 pandemic.MethodThe study was conducted on a group of 700 people aged 18 and over living in Poland. An anonymous online questionnaire was used in this cross-sectional study. The psychological impact of COVID-19 was measured using the Revised Event Impact Scale (IES-R) and the Depression, Anxiety, and Stress Scale (DASS - 21). The quality of life was assessed using the WHOQOL-BREF.ResultsIn Poland, a high average level of post-traumatic stress was found as a result of the COVID-19 pandemic, with at least the minimum level occurring in all surveyed people. There was also a high incidence of depression (48.00%), anxiety (39.29%), and stress (54.86) in the first phase of the pandemic. The average level of quality of life in Poland was the lowest for the physical domain and amounted to 49.56 (SD = 11.71). The standard of living in the psychological domain was 60.26 (SD = 13.14).ConclusionsThe pandemic is having a significant impact on human mental health. The very high average levels of post-traumatic stress, stress, anxiety, and depression as well as low quality of life make it necessary to consider interventions that will favor the use of more adaptive defense mechanisms and build mental resilience during an infectious disease pandemic and its long-term consequences.

Mental health in the general population over 1 year of the Covid-19 pandemic: findings from Ireland

Abstract Background The effects of the Covid-19 pandemic and associated public health measures on mental health is a cause of increasing concern. We have measured indices of mental health among adults in the general population in the Republic of Ireland (ROI) during the period of May 2020-April 2021. Methods Nationally representative cross-sectional telephone survey with data collected in ROI during four study waves involving 3,920 participants: Wave 1: May 26-June 17, 2020 (N = 969), Wave 2: July 1-23, 2020 (N = 1014), Wave 3: September 5-28, 2020 (N = 1008), Wave 4: April 16-28, 2021 (N = 929). Participants were recruited from adults resident in RoI, aged 18 years+ using random-digit-dialling of land lines and mobile phones and interviewed by a professional market research organisation (Ipsos MRBI). Data from Waves 1-4 will be presented including trends over the 12-month period. Finding from Waves 1 and 2 are presented here. Mental health was assessed using the Patient Health Questionnaire Anxiety Depression Scale (PHQ-ADS), including standard questions on self-harm and/or suicidal thoughts. Results Of the 1,983 participants from Waves 1-2, 27.7% (n = 549; 95%CI:0.26%-30%) reported symptoms of depression and anxiety, 74 (3.8%;95%CI:3%-5%) disclosed self-harm and/or suicidal thoughts. Female participants (RR:1.60, 95%CI:1.37-1.87), employed individuals experiencing work change (RR:1.50,95%CI:1.24-1.82), participants cocooning due to a health condition (RR:1.34,95%CI:1.08-1.66), those self-isolating (RR:1.25,95%CI:1.03-1.51) and those reporting moderate-heavy drinking (RR:1.27,95%CI:1.09-1.47) were at increased risk of depression and anxiety symptoms. Participants aged 18-29 and those in the two lowest income categories were most likely to report self-harm and/or suicidal thoughts. Conclusions The prevalence of țanxiety and depression in the general population has increased relative to pre-pandemic estimates in response to the Covid-19 pandemic and associated public health measures. Key messages In nationally representative telephone surveys of Irish adults conducted following the onset of the Covid-19 pandemic, the prevalence of anxiety and depression is estimated at approximately 30%. Higher than average levels of anxiety or depression were reported in females, those who had experienced a change in their work, individuals cocooning and those with moderate to heavy drinking.

NURSE’S SOCIAL SUPPORT TOWARD FAMILY’S STRESS AND ANXIETY LEVEL IN INTENSIVE CARE UNIT

Background: The ICU is a room for critical patients who require continuous airway breathing circulation support. This also affects the family psychology in the form of stress and anxiety. One of the urgent but often overlooked factor in this case is that the families of patients in the ICU need social support and this is expected to be provided by the nurses. Purpose: To examine the relationship between social support nurses and the level of stress and anxiety of the patient's family in ICU. Methods: This study was an observational analytic study with a cross sectional approach. The population in this study were the families of patients who were treated in the critical care room from May to June 2019. The sampling technique was simple random and 95 respondents met the inclusion and exclusion criteria. The instrument used to measure social support is the CCFNI (Critical Care Family Need Information) while to measure the level of stress and anxiety using DASS 42. Both of these instruments have been tested for validity and reliability. Results: The results showed that the majority of respondents had a Social Support Fulfilled (66%), majority of respondents had a normal stress level (55%) and the majority of respondents had normal anxiety levels (34%). The results of the Wilcoxon test statistical test showed that social support with a stress level of p value &lt;0.001, and social support with anxious level showed p&lt;0.01. Conclusion: Nurse's social support is needed by the families of patients who are admitted to the intensive care unit.

Evaluation of the leading typological characteristics of temperament, severity and features of accentuated personality traits and psychodynamic features of personality in practically healthy women without and taking into account the somatotype

Annotation. Research on the relationship of the human body with its psychological characteristics and behavioral elements is currently of great value for integrative medicine, psychology and pedagogy. A deep understanding of this issue allows you to prevent and correct unwanted psychological manifestations in groups of people who have this predisposition, as well as help to find the right approach in educational and therapeutic work with such people. The purpose of the study is to evaluate the leading typological characteristics of temperament, severity and features of accentuated personality traits and psychodynamic personality traits of almost healthy women without and taking into account the somatotype. Primary anthropo-somatotypological and personality indicators of practically healthy Ukrainian women aged 21 to 35 years of different somatotypes were selected from the database of materials of the research center of National Pirogov Memorial Medical University, Vinnytsya. All women were evaluated by Eysenck leading typological characteristics of temperament with the help of personal questionnaires; psychodynamic features of Spielberger's personality in Khanin's modification; expressions and features of accentuated personality traits according to Shmishek. Statistical processing of the results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. It was found that almost healthy women without somatotype are characterized by extroversion (32.67 %) and ambiversion (29.70 %), average level of neuroticism (35.64 %), insincerity (66.34 %), average level of anxiety (62.38 %), predominance of hyperthymic (33.66 %), exalted (25.74 %), cyclothymic (22.77 %) type of character accentuation. Women of mesomorphic somatotype are characterized by potential extroversion (33.33 %) and potential introversion (27.27 %), potentially high levels of neuroticism (39.39 %), insincerity (72.73 %), average level of anxiety (60.61 %), high level of personal1 anxiety (60.61 %), predominance of exalted (42.42 %), hyperthymic (30.30 %), cyclothymic (27.27 %) and emotional (24.24 %) types of character accentuation. Among women of ectomorphic somatotype, the most common are individuals with ambiversion (31.82 %) and potential extroversion (31.82 %), with a medium level of neuroticism (36.36 %), insincerity (72.73 %), high and medium levels of situational anxiety (50.00 % each), high personal anxiety (54.55 %), the predominance of hyperthymic (22.73 %), cyclothymic (18.18 %) and pedantic (18.18 %) types of character accentuation. Among women of endo-mesomorphic somatotype, the most common are those with potential introversion (31.82 %), ambiversion (36.36 %) and potential extroversion (27.27 %), with an average level of neuroticism (63.64 %), sincerity (50.00 %), an average level of situational (77.27 %), the average level of personal anxiety (68.18 %), a significant predominance of the hyperthymic type of character accentuation (40.91 %). Among women with average intermediate somatotype, the most common are individuals with ambiversion (41.18 %) and potential extroversion (35.29 %), with medium and potentially high levels of neuroticism (29.41 % in both cases), insincerity (76.47 %), average situational (58.82 %) and personal anxiety (70.59 %), the predominance of (significant) hyperthymic (52.94 %) and cyclothymic (35.29 %) types of character accentuation. Thus, to study the psychological characteristics of people of different constitutional types, it is important to follow an interdisciplinary approach, in which the optimal use of traditional anthropometric techniques in combination with psychological tests.

Leading typological characteristics of temperament and psychodynamic personality traits in men with psoriasis without and taking into account the somatotype

Annotation. One of the most important problems of modern dermatology is the individualization of programs for diagnosis, treatment and prevention of skin diseases. The success of its solution largely depends on how fully, systematically will be described and somatic and mental components of the patient’s personality, taking into account the full range of biological and mental factors that affect his health. The aim of the study was to establish the features of the leading typological characteristics of temperament and psychodynamic personality traits between healthy and psoriatic men without taking into account somatotype and representatives of mesomorphic and endo-mesomorphic somatotypes. Men aged 22 to 35 years, patients with psoriasis (n=100, including 32 with mild and 68 with severe) conducted an anthropometric examination according to V. V. Bunak Somatotype was calculated according to the mathematical scheme of J. Carter and B. Heath. The PASI (Psoriasis Area and Severity Index) was used to clinically assess the severity and area of psoriatic lesions. The control group consisted of anthropometric data of 82 practically healthy men of the same age group from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya. Evaluation of the leading typological characteristics of temperament was determined by G. Eysenck, psychodynamic personality traits – by C. D. Spielberger in the modification of Y. L. Khanin Statistical processing was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. When comparing the studied indicators between groups with different disease course, significantly higher and tendencies to higher values of the percentage were found: persons with potential introversion among patients in general (19.12 %) and endo-mesomorphs (22.22 %) with severe course compared to healthy subjects without taking into account the somatotype (8.54 %) and the control group of a similar somatotype (0 %); persons with a low level of neuroticism among patients in general (50.00 %), mesomorphs (46.43 %) and endo-mesomorphs (75.00 %) with mild psoriasis compared with patients without somatotype, mesomorphs and endo-mesomorphs with severe dermatosis (19.12 %., 18.18 % and 11.11 %); persons with an average level of neuroticism among patients in general (22.06 %) and mesomorphs (20.00 %) with severe psoriasis compared with patients without somatotype and mesomorphs with mild dermatosis (3.13 %, 3.57 %); persons who answered insincerely, among patients with mild psoriasis (87.50 %) compared with patients with severe psoriasis (66.18 %); persons with a low level of situational anxiety among patients in general (12.50 %) and mesomorphs (14.29 %) with a mild course of psoriasis compared with patients without somatotype and mesomorphs with a severe course of dermatosis (2.94 % and 3.04 %); persons with a low level of situational anxiety among patients in general (21.88 %) and mesomorphs (17.86 %) with a mild course of psoriasis compared with patients without somatotype and mesomorphs with a severe course of dermatosis (8.82 % and 5.45 %). When comparing the studied indicators between groups with different body type, significantly higher and tendencies to higher values of the percentage of people with an average level of situational anxiety among endo-mesomorphs with mild and severe psoriasis (100 % in both cases) compared with mesomorphs. the corresponding severity of the disease (63.64 % and 46.43 %); persons with a high level of situational anxiety among mesomorphs with severe psoriasis (30.91 %), compared with endo-mesomorphs with a corresponding severity of the disease (0 %); persons with a low level of personal anxiety among endo-mesomorphs suffering from severe psoriasis (22.22 %), compared with mesomorphs suffering from dermatosis of similar severity (5.45 %); persons with a low level of personal anxiety among healthy endo-mesomorphs (46.15 %) compared with healthy mesomorphs (12.82 %); persons with an average level of personal anxiety among healthy mesomorphs (71.79 %) compared with healthy endo-mesomorphs (30.47 %). Thus, our study, conducted using a constitutional approach, allowed us to describe systemic portraits of patients with psoriasis, including the strengths and weaknesses of their morphological and mental organization, necessary to justify differentiated approaches to planning health and prevention measures.

Молекулярно-генетична концепція формування психотипів особистості в дітей при ожирінні, асоційованому з лактозною інтолерантністю

Мета дослідження — визначення асоціації однонуклеотидних поліморфізмів (SNP) у гені лактази (LCT) із формуванням ожиріння в дітей на основі вивчення особистісної та реактивної тривожності (тест Спілбергера — Ханіна) та оцінки якості життя (методика MOS-SF-36). Матеріали та методи. Проведено генотипування за поліморфним локусом енхансера гена MCM6 (minichromosome maintenance complex component 6), що кодує експресію гена LCT у 62 дітей віком 12–18 років із різними формами ожиріння. До першої групи (n = 31) увійшли діти, які мали рецесивну алель С/С 13910 поліморфізму rs4988234. Другу групу (n = 31) становили діти з домінантною гомозиготною алеллю Т/Т 13910 або гетерозиготною алеллю С/Т 13910. Результати. Установлено 6-кратне збільшення частоти зустрічальності генотипу С/С 13910 у дітей із тяжкими формами ожиріння (індекс маси тіла &gt; 97-го перцентиля). Доведено наявність високого рівня особистісної (46,5 ± 0,4) та середнього рівня реактивної тривожності (33,2 ± 0,9) у дітей із генотипом С/С 13910 порівняно з помірно високим рівнем особистісної (37,5 ± 0,8) та низьким рівнем реактивної тривожності (24,3 ± 0,8) у пацієнтів із генотипами С/Т та Т/Т 13910 (р &lt; 0,05). Наведено результати оцінки якості життя підлітків з ожирінням, що характеризуються погіршенням рівня фізичного компонента (РН) здоров’я при генотипі С/С 13910, а саме в юнаків за рахунок зниження показника рольового функціонування, обумовленого фізичним станом (RP), у дівчат за рахунок зниження рівня загального здоров’я (GH), р &lt; 0,05. Висновки. Таким чином, дослідження однонуклеотидних поліморфізмів у гені LCT (rs4988234) виявило асоціацію генотипу С/С 13910 із тяжкими формами абдомінального ожиріння в дітей (індекс маси тіла &gt; 97-го перцентиля), підвищеним рівнем тривожності та зниженням оцінки якості життя за рахунок фізичного компонента здоров’я, що може бути використане при моделюванні поведінкової інтервенції та потребувати можливої замісної терапії препаратами екзогенної лактази.

Psychopersonal characteristics of women with varying degrees of menopausal disorders

The perimenopausal period is the age of the highest spiritual and intellectual development of a woman; therefore, neurovegetative and psycho-emotional disorders of this period acquire a pecial medical and social value and require an interdisciplinary approach.&#x0D; Purpose of the study. To identify the psychological characteristics of women with mild and moderate menopausal disorders in the perimenopausal period.&#x0D; Materials and methods. A total of 51 women were examined in the perimenopausal period: I main group – 20 patients with a low degree of CS, II main group – 16 women with menopausal disorders of moderate severity; the control group consisted of 15 healthy women. The severity of menopausal syndrome was determined using a modified menopausal Cooperman's index. All patients underwent psychodiagnostic examination using reactive and personal anxiety scales according to Ch.D. Spielberg and J.L. Hanina, G. Eisenko's test questionnaire, the Women's Sexual Function Index (FSFI) questionnaire, used the SF-36 (Medical Outcomes Study Short Form) general questionnaire to assess quality of life.&#x0D; Results. In women of the main groups, neurovegetative (14,5 ± 2,6 and 26,6 ± 4,2 points in the first and second groups of observation) and psycho-emotional disorders (4,9 ± 1,3 and 11,2 ± 1,6 points) prevailed. respectively). Hormone levels (FSH, E2, PRL) corresponded to perimenopausal values, but were significantly different from those of the control group. Identified individual-personal properties of women with the CS, in particular introversion and emotional instability. A comparative analysis on the SpielbergKhanin scales showed that more than half (55,0%) in the first main group and the majority (81,25%) of women in the second main group versus 33,35% in the control group (p ˂ 0,05), a high level of personal anxiety was diagnosed; the average level of situational anxiety was highest among women in group II – 54,83 ± 6,0 points versus 43,2 ± 5,3 points in the first group and 36,3 ± 4,8 points in patients without menopausal disorders (p ˂ 0,05). In 24 (77,42%) women of the main group, sexual dysfunction was detected, while its degree was greatest with moderately severe climacteric disorders. Menopausal disorders of varying severity, increased anxiety and neuroticism, sexual dysfunction affected the quality of life of patients.&#x0D; Conclusion. Formed psychopersonal characteristics of women with varying degrees of menopausal disorders in the perimenopausal period.

Basal and LPS-stimulated inflammatory markers and the course of anxiety symptoms

A cross-sectional relationship between low-grade inflammation –characterized by increased blood levels of C-reactive protein (CRP) and pro-inflammatory cytokines– and anxiety has been reported, but the potential longitudinal relationship has been less well studied. We aimed to examine whether basal and lipopolysaccharide (LPS-)induced levels of inflammatory markers are associated with anxiety symptom severity over the course of nine years.We tested the association between basal and LPS-induced inflammatory markers with anxiety symptoms (measured with the Beck’s Anxiety Inventory; BAI, Fear Questionnaire; FQ and Penn’s State Worry Questionnaire; PSWQ) at 5 assessment waves over a period up nine years. We used multivariate-adjusted mixed models in up to 2867 participants of the Netherlands Study of Depression and Anxiety (NESDA).At baseline, 43.6% of the participants had a current anxiety disorder, of which social phobia (18.5%) was most prevalent. Our results demonstrated that baseline inflammatory markers were significantly associated with several outcomes of anxiety at baseline over nine subsequent years. BAI subscale of somatic (arousal) symptoms of anxiety, and FQ subscale of agoraphobia demonstrated the strongest effects with standardized beta-coefficients of up to 0.14. The associations were attenuated by 25%-30% after adjusting for the presence of (comorbid) major depressive disorder (MDD), but remained statistically significant.In conclusion, we found that participants with high levels of inflammatory markers have on average high levels of anxiety consisting of physical arousal and agoraphobia, which tended to persist over a period of nine years, albeit with small effect sizes. These associations were partly driven by co-morbid depression.