PurposeThis study aims to identify the key enablers for the adoption of Industry 4.0 (I4.0) in the automobile industry of India, which has been severely impacted by COVID-19. Adopting I4.0 will provide organizations greater flexibility and resilience during the COVID-19 pandemic.Design/methodology/approachBased on the literature review and experts’ opinions, 21 enablers were identified. Further, contextual relationships among the identified factors and a hierarchical digraph was developed by using the total interpretive structural modelling (TISM) technique. Finally, fuzzy cross-impact matrix multiplication applied to classification (MICMAC) analysis was conducted to classify the enablers into different categories based on their dependence and driving power.FindingsThe results indicate that top management support, clarity on government policy, strategic vision on I4.0 and development of new industrial policy are the most influential factors, with the highest driving power placed at the bottom of the TISM hierarchical model. Furthermore, agile workforce, smart HR practices and IT standardization and security are identified as linkage enablers with the most driving and dependency power.Practical implicationsThe hierarchical TISM model and fuzzy MICMAC approach provide a comprehensive understanding of the I4.0 implementation process through a visual, logical structure to the managers. It will help the researchers and practitioners understand the contextual relationship among various enablers in fostering the I4.0 adoption process and digital reorganization in the automobile industry during the COVID-19 pandemic.Originality/valueThis study provides a holistic TISM hierarchical framework on I4.0 adoption that will elevate the next maturity level of innovation adoption and may act as a blueprint for automobile industries during the COVID-19 pandemic.