The seasonal and inter-annual variations of Arctic cyclone are investigated. An automatic cyclone tracking algorithm developed by University of Reading was applied on the basis of European Center for Medium-range Weather Forecasts (ECMWF) ERA-interim mean sea level pressure field with 6 h interval for 34 a period. The maximum number of the Arctic cyclones is counted in winter, and the minimum is in spring not in summer. About 50% of Arctic cyclones in summer generated from south of 70°N, moving into the Arctic. The number of Arctic cyclones has large inter-annual and seasonal variabilities, but no significant linear trend is detected for the period 1979–2012. The spatial distribution and linear trends of the Arctic cyclones track density show that the cyclone activity extent is the widest in summer with significant increasing trend in CRU (central Russia) subregion, and the largest track density is in winter with decreasing trend in the same subregion. The linear regressions between the cyclone track density and large-scale indices for the same period and pre-period sea ice area indices show that Arctic cyclone activities are closely linked to large-scale atmospheric circulations, such as Arctic Oscillation (AO), North Atlantic Oscillation (NAO) and Pacific-North American Pattern (PNA). Moreover, the pre-period sea ice area is significantly associated with the cyclone activities in some regions.