Autobiographical Recall Research Articles

Spatial and temporal heterogeneity of neural responses in human posteromedial cortex

Neuroimaging evidence supports a role of the default mode network (DMN) in spontaneous thought and goal-driven internally oriented processes, such as recalling an autobiographical event, and has demonstrated its deactivation during focused, externally oriented attention. Recent work suggests that the DMN is not a homogeneous network but rather is composed of at least several subnetworks, which are engaged in distinct functions; however, it is still unclear if these different functions rely on the same neuronal populations. In this study, we used intracranial EEG to record from the posteromedial cortex (PMC), a core hub of the DMN, in 13 human subjects, during autobiographical memory retrieval (internally oriented), arithmetic processing (externally oriented), and cued rest (spontaneous thought), allowing us to measure activity from anatomically precise PMC sites with high temporal resolution. We observed a heterogeneous, yet spatially organized, pattern of activity across tasks. Many sites, primarily in the more ventral portion of PMC, were engaged during autobiographical recall and suppressed during arithmetic processing. Other more dorsal PMC sites were engaged during the cued-rest condition. Of these rest-active sites, some exhibited variable temporal dynamics across trials, possibly reflecting various forms of spontaneous thought, while others showed only transient activity at the beginning of cued-rest trials (i.e., after a switch from a task to cued rest), possibly involved in shifting the brain from a more focused to a more exploratory attentional state. These results suggest heterogeneity of function even within an individual node of the DMN.

Seeing life through rose-colored spectacles: Autobiographical memory as experienced in Korsakoff's syndrome.

We investigated whether patients with Korsakjoff's Sybdrome (KS) would demonstrate a discrepancy between (low) autobiographical specificity and (high) sense of reliving. We invited 20 KS patients and 24 controls to retrieve personal memories. After memory retrieval, they were invited to rate subjective characteristics of their recall (e.g., reliving, travel in time, remembering, realness). Besides this rating, we analyzed memories objectively with regard to specificity. Analysis demonstrated poorer sense of reliving and memory specificity in KS patients than in controls. Critically, a discrepancy (i.e., higher level of sense of reliving than of specificity) was observed in KS participants but not in controls. We propose a hypothesis of "genuine consciousness experience" in which the discrepancy between sense of reliving and specificity mirrors how KS patients can benefit from an authentic experience of the past despite compromise in their autobiographical recall.

Experimental Methods for Inducing Basic Emotions: A Qualitative Review

Experimental emotion inductions provide the strongest causal evidence of the effects of emotions on psychological and physiological outcomes. In the present qualitative review, we evaluated five common experimental emotion induction techniques: visual stimuli, music, autobiographical recall, situational procedures, and imagery. For each technique, we discuss the extent to which they induce six basic emotions: anger, disgust, surprise, happiness, fear, and sadness. For each emotion, we discuss the relative influences of the induction methods on subjective emotional experience and physiological responses (e.g., heart rate, blood pressure). Based on the literature reviewed, we make emotion-specific recommendations for induction methods to use in experiments.

Emotion-Focused Therapy for Autism Spectrum Disorder: A Case Conceptualization Model for Trauma-Related Experiences

People with autism spectrum disorder (ASD) report painful experiences through emotional misunderstandings with typically developing peers. There are limited intervention methodologies for ASD on the impact of emotional injuries and how to work with resulting trauma. This paper presents a rational-empirical model of trauma-related experiences with the first presentation of a new case conceptualization model for emotion-focused therapy for ASD. It describes the transformation of problematic emotion schemes through a sequence of emotional processing steps illustrated with a case example. These steps include: overcoming differentiation of core painful feelings (such as loneliness, shame, and fear); autobiographical memory recall of distanced trauma, using a novel method of video Interpersonal Process Recall; and articulation of the unmet needs contained in core painful feelings. This is followed by the expression of an emotional response to those feelings/needs; typically, self-soothing, protective anger and compassion responses offered interpersonally by group members. These emerging adaptive emotions facilitate mentalization of self and other that strengthens intrapersonal and interpersonal agency. This rational-empirical case conceptualization acts as a hypothesis for testing in subsequent trials.

Negative Autobiographical Memory in Depression Reflects Elevated Amygdala-Hippocampal Reactivity and Hippocampally Associated Emotion Regulation

BackgroundDysregulated autobiographical recall is observed in major depressive disorder (MDD). However, it is unknown whether people with MDD show abnormalities in memory-, emotion-, and control-related brain systems during reactivity to and regulation of negative autobiographical memories. MethodsWe used functional magnetic resonance imaging to identify neural mechanisms underlying MDD-related emotional responses to negative autobiographical memories and the ability to downregulate these responses using a cognitive regulatory strategy known as reappraisal. We compared currently depressed, medication-free patients with MDD (n = 29) with control participants with no history of depression (n = 23). ResultsRelative to healthy control participants, medication-free MDD patients reported greater negative emotion during recall but relatively intact downregulation success. They also showed elevated amygdala activity and greater amygdala-hippocampal connectivity. This connectivity mediated the effect of MDD on negative emotional experience. When reappraising memories (vs. recalling from an immersed perspective), the MDD and control groups showed comparable recruitment of the prefrontal, parietal, and temporal cortices, and comparable downregulation of the amygdala and anterior hippocampus. However, MDD patients showed greater downregulation of the posterior hippocampus, and the extent of this downregulation predicted successful reduction of negative affect in MDD patients only. ConclusionsThese data suggest amygdala-hippocampal connectivity and posterior hippocampal downregulation as brain mechanisms related to elevated emotional reactivity and atypical emotion regulation in MDD.

Retrieving autobiographical experience of painful events in a phantom limb: brain concomitants in a case report

ABSTRACTWe report the case of a patient who had an important experience with painful events, allowing the investigation of brain concomitants to painful (P) memories in fMRI. The patient had to recall P events that were contrasted with non-painful (NP) memories. Painful memories of the right lower limb activated the left paracentral lobule,fronto-insular operculum and superior parietal cortex. Additionally, whilst the recall of non-painful events activated the hippocampus, the recall of painful events did not enhance the hippocampal signal to significant levels. These suggest that brain activations differ for the autobiographical recall of painful and non-painful memories.

Experimental Manipulations of Personal Control do Not Increase Illusory Pattern Perception

We report seven experiments to investigate the effects of control threat manipulations on different measures of illusory pattern perception: magical thinking (Study 1–3), conspiracy beliefs (Study 4), paranormal beliefs (Study 5) and agent detection (Study 6 and 7). Overall we did not find evidence for an effect of control threat on any of our relevant dependent measures. By using Bayesian analyses we obtained positive evidence for the null-hypothesis that an experimentally induced loss of control does not affect illusory pattern perception. Finally, by re-conducting a recent meta-analysis we found strong evidence for publication bias and a relatively small effect size for control-threat manipulations. Together, these results cast doubt on the potential efficacy of experimental autobiographical recall manipulations to manipulate feelings of control.

Greater specificity of activity memories in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Implications for exercise-based treatment

PurposeAutobiographical memory is crucial to goal attainment, thus it may influence coping with chronic illness. Autobiographical memory was investigated in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and healthy people. Two contrasting hypotheses were tested. On the basis of Williams and colleagues’ model of overgeneral memories in depression, and the high co-morbidity between CFS/ME and depression, we predicted overgeneral autobiographical memories in the CFS/ME group. In contrast, on the basis of a postulated oversensitization of the central nervous system in the CFS/ME population and their amplified attention towards anything that might threaten their energy balance, such as activity, we predicted that autobiographical activity memories in CFS/ME would be more specific than in healthy controls. MethodsWe employed modified cued autobiographic recall in CFS/ME (N = 89) and healthy (N = 61) participants, who were asked to recall particular past events when they experienced happiness, pain, fatigue, or were physically active. Levels of psychological distress, rumination, and behavioural disengagement were assessed. ResultsCFS/ME participants recalled significantly more specific autobiographical memories of past physical activity, compared to healthy controls. Within the CFS/ME group, lower levels of ruminating about past activity were significantly related to greater specificity in recall of activity. Further, those CFS/ME participants who recalled more specific autobiographical activity memories reported significantly lower levels of behavioural disengagement. ConclusionCFS/ME individuals’ autobiographical memory for activity differs both from healthy individuals and the typical pattern found in depression. The effect of specific activity memories could be utilized in exercise-based treatment of CFS/ME.

Sadness and ruminative thinking independently depress people's moods.

Depression and rumination often co-occur in clinical populations, but it is not clear which causes which, or if both are manifestations of an underlying pathology. Does rumination simply exacerbate whatever affect a person is experiencing, or is it a negative experience in and of itself? In two experiments we answer this question by independently manipulating emotion and rumination. Participants were allocated to sad or neutral (in Experiment 1), or sad, neutral or happy (Experiment 2) mood conditions, via a combination of emotionally evocative music and autobiographical recall. Afterwards, in both studies, participants either ruminated by thinking about self-relevant statements or, in a control group, thought about self-irrelevant statements. Taken together, our data show that, independent of participants' mood, ruminators reported more negative affect relative to controls. The findings are consistent with theories suggesting that self-focus is itself unpleasant, and illustrate that depressive rumination comprises both affective and ruminative components, which could be targeted independently in clinical samples.

When expressing forgiveness backfires in the workplace: victim power moderates the effect of expressing forgiveness on transgressor compliance

ABSTRACTExpressing (vs. withholding) forgiveness is often promoted as a beneficial response for victims. In the present research, we argue that withholding (vs. expressing) forgiveness can also be beneficial to victims by stimulating subsequent transgressor compliance – a response that is valuable in restoring the victim’s needs for control. Based on deterrence theory, we argue that a victim’s withheld (vs. expressed) forgiveness promotes transgressor compliance when the victim has low power, relative to the transgressor. This is because withheld (vs. expressed) forgiveness from a low-power victim elicits transgressor fear. On the other hand, because people are fearful of high-power actors, high-power victims can expect high levels of compliance from a transgressor, regardless of whether they express forgiveness or not. A critical incidents survey (Study 1) and an autobiographic recall study (Study 2) among employees, as well as a laboratory experiment among business students (Study 3), support these predictions. These studies are among the first to reveal that withholding forgiveness can be beneficial for low-power victims in a hierarchical context – ironically, a context in which offering forgiveness is often expected.

Phenomenological characteristics of autobiographical memory in Korsakoff's syndrome.

A body of research suggests compromise of autobiographical memory in Korsakoff's syndrome (KS). The present paper extends this literature by investigating the subjective experience of autobiographical recall in the syndrome. Patients with KS and controls were asked to retrieve autobiographical memories. After memory retrieval, participants were asked to rate phenomenological characteristics of their memories (i.e., reliving, back in time, remembering, realness, visual imagery, auditory imagery, language, emotion, rehearsal, importance, spatial recall and temporal recall). Analysis showed lower "Mean Phenomenological Experience" in the Korsakoff patients than in controls. However, the Korsakoff patients attributed relatively high emotional value and importance to their memories. Although our findings suggest compromised phenomenological reliving of autobiographical memory in patients with KS, affective characteristics such as emotion and importance are likely to play a main role in the subjective experience of the past in these patients.

Attentional biases for threat after fear-related autobiographical recall

ABSTRACTBackground: Previous studies suggested that affective state could enhance stimulus salience and modulate attention allocation for mood-congruent information, but contrasting data have been reported on the effects of mood induction on attentional biases for threat (ABTs) in non-clinical individuals.Objective: We aimed to assess whether laboratory-induced negative mood can increase individuals’ tendency to allocate attention on threatening stimuli, thus determining a difficulty in attentional disengagement from threat. We also aimed at assessing whether level of trait anxiety could modulate the effect of mood induction on attentional biases.Methods: We used an autobiographical episode recall procedure for mood induction (fear, happiness and neutral episode recall), and an exogenous cueing task with threatening and non-threatening images to assess attentional biases in 120 undergraduate students.Results: Participants showed a significant difficulty in disengaging attention from threat after recalling fear-related episodes, independently from their trait anxiety level.Conclusions: These findings clarify that the ABTs are not exclusive to anxiety disorders or high trait anxiety individuals, and could also arise in non-clinical individuals in a fearful context.

Perceived Shared Condemnation Intensifies Punitive Moral Emotions

Punishment facilitates large-scale cooperation among humans, but how punishers, who incur an extra cost of punishment, can successfully compete with non-punishers, who free-ride on the punisher’s policing, poses an evolutionary puzzle. One answer is by coordinating punishment to minimise its cost. Notice, however, that in order to effectively coordinate their punishment, potential punishers must know in advance whether others would also be willing to punish a particular norm violator. Such knowledge might hinder coordination by tempting potential punishers to free-ride on other punishers. Previous research suggests that moral emotions, such as moral outrage and moral disgust, serve as a commitment device and drive people to carry out the costly act of punishment. Accordingly, we tested whether the perception of socially shared condemnation (i.e., knowledge that others also condemn a particular violator) would amplify moral outrage and moral disgust, and diminish empathy for the violator. Study 1 (scenario-based study) revealed that perceived shared condemnation was correlated positively with moral outrage and moral disgust, and negatively with empathy. Study 2 experimentally demonstrated that information indicating that others also condemn a particular norm violation amplified moral outrage. Lastly, Study 3 (autobiographical recall study) confirmed the external validity of the finding.

Can an experimental self-efficacy induction through autobiographical recall modulate analogue posttraumatic intrusions?

Background and objectivesResearch has shown a link between self-efficacy appraisals and PTSD symptoms. Less is known about the relation between perceived self-efficacy and specific PTSD symptoms such as intrusions. These two experiments tested the causal relationship between perceived self-efficacy and intrusions from a trauma film. MethodsIn Experiment I, healthy student participants received a self-efficacy manipulation consisting of the recall of autobiographical memories of success (high self-efficacy condition), failure (low self-efficacy condition) or ‘important’ memories (control condition). Afterwards, they viewed a trauma film and recorded their intrusions of the film in the following week. In Experiment II the self-efficacy manipulation was given after the film. ResultsIn contrast to expectations, the high self-efficacy condition reported a higher number of intrusions relative to the low self-efficacy condition in both experiments. LimitationsThe trauma film provides experimental control but precludes generalization to real-life trauma. The effect of the experimental manipulation was small. The control condition also affected mood and confidence. ConclusionsThe results suggest that the relation between self-efficacy and intrusions development is causal, but not straightforward. Recalling personal memories of success before or after a traumatic event may increase the risk of developing intrusions, at least under some circumstances. Conversely, recalling past failure experiences may be protective, perhaps by preparing the individual for adversity, or prompting them to search for coping strategies that have been successful in the past. Overall, autobiographical recall involves complex processes related to the self that could be useful but need to be more fully understood.

Describe yourself to improve your autobiographical memory: A study in Alzheimer's disease

This study investigated whether retrieval of information related to conceptual self (i.e., self-images that encompass general factual and evaluative knowledge of one's identity) would improve autobiographical memory in Alzheimer's disease (AD). Participants with AD and controls were asked to retrieve autobiographical memories after providing statements to the question “Who am I? and after a control condition consisting of reading a general text. Autobiographical recall was analyzed with respect to specificity (general vs specific event), context recall (information describing the “when, where, and who” as well as affective states), and reliving (the subjective experience of recall). AD participants showed higher specificity, context recall and reliving after the “Who am I?” statements than after the text reading, and controls showed higher context recall after the former than after the latter condition. These findings highlight the relationship between self and autobiographical memory in AD and demonstrate how retrieval of information related to conceptual self may influence autobiographical memory in the disease.

Assessing the effectiveness of drawing an autobiographical memory as a mood induction procedure in children

The objective of our study was to examine the effectiveness of a new version of the autobiographical recall procedure (i.e., drawing a happy personal event) in eliciting a positive mood in 6-, 8-, and 10-year-old children and to compare the drawing condition to the more classical telling condition. The mood of children was assessed before and after induction using the Self-Assessment Manikin (SAM) and across the two emotional dimensions of valence and arousal. The results showed that the drawing condition was as effective as the telling condition for inducing a positive mood. Furthermore, in the drawing condition, children reported feeling calmer than in the telling condition, suggesting that drawing was more likely to help children regulate their emotional state. The drawing procedure could be used in future research aiming to induce positive moods in school-aged children, to help further investigate the relationship between cognition and emotion.

S.16.05 - Attenuated resting-state default mode network connectivity in remitted depression after sad autobiographical recall

The expanding legalization of cannabis across the United States is associated with increases in cannabis use, and accordingly, an increase in the number and severity of individuals with cannabis use disorder (CUD). The lack of FDA-approved pharmacotherapies and modest efficacy of psychotherapeutic interventions means that many of those who seek treatment for CUD relapse within the first few months. Consequently, there is a pressing need for innovative, evidence-based treatment development for CUD. Preliminary evidence suggests that repetitive transcranial magnetic stimulation (rTMS) may be a novel, non-invasive therapeutic neuromodulation tool for the treatment of a variety of substance use disorders (SUDs), including recently receiving FDA clearance (August 2020) for use as a smoking cessation aid in tobacco cigarette smokers. However, the potential of rTMS for CUD has not yet been reviewed. This paper provides a primer on therapeutic neuromodulation techniques for SUDs, with a particular focus on reviewing the current status of rTMS research in people who use cannabis. Lastly, future directions are proposed for rTMS treatment development in CUD, with suggestions for study design parameters and clinical endpoints based on current gold-standard practices for therapeutic neuromodulation research.

Role of anxiety and brooding in specificity of autobiographical recall.

Overgeneral schemas and lack of autobiographical memory (AM) specificity about our past experiences can predict mood disturbance. Rumination, functional avoidance and executive processes are the main explanatory variables of such overgenerality. However, in non-clinical samples, rumination predicts overgenerality most consistently after the induction of dysphoric mood. Anxiety also activates rumination. Furthermore, anxiety predicts memory performance and has effects on mood which are independent of the effects of rumination. So, what might be the role of anxiety in autobiographical memory performance? A sample of 210 voluntary participants reported measures of autobiographical memory, anxiety, rumination (brooding and reflection), functional avoidance and executive functions (semantic and phonetic verbal fluency task). Autobiographical performance (specificity) was negatively associated with brooding and age and positively with phonetic verbal fluency but not with functional avoidance and anxiety. However, anxiety and brooding were positively correlated even after controlling for depression scores. Moreover, using structural equationmodeling, anxiety showed a significant indirect effect on autobiographical specificity through brooding rumination. These results suggest a possible association of anxiety with autobiographical recall through brooding rumination.

Phenomenological Characteristics of Autobiographical Memories: Responsiveness to an Induced Negative Mood State in Those With and Without a Previous History of Depression.

In this study we investigated the relative accessibility of phenomenological characteristics in autobiographical memories of 104 students with and without a previous history of a depression. Participants recalled personal events that were elicited with cue words and then asked to rate these personal events for a number of phenomenological characteristics. The characteristics were typicality, rumination, valence, importance of others, expectancy, desirability, and personal importance. The effects of previous history of depression (without history or with previous history of depression) and self-reported mood (pre- and post-negative mood induction) on autobiographical recall was examined by employing a mixed factor design. Self-reported mood was measured as a manipulation check, before and after Mood Induction Procedure. Typicality, rumination and personal importance showed significant interaction effects in those with a history of depression. Ordinal regression supported the finding that those with a history of depression had a higher chance of typicality and personal importance than those without a history of depression. The results indicate that recall of autobiographical characteristics is in part dependent on induced negative mood state and on previous history of depression. The findings may prompt future research into targeted interventions that reduce individual tendencies for heightened cognitive reactivity in negative mood states for those with a history of depression.

Phenomenological Reliving and Visual Imagery During Autobiographical Recall in Alzheimer's Disease.

Multiple studies have shown compromise of autobiographical memory and phenomenological reliving in Alzheimer's disease (AD). We investigated various phenomenological features of autobiographical memory to determine their relative vulnerability in AD. To this aim, participants with early AD and cognitively normal older adult controls were asked to retrieve an autobiographical event and rate on a five-point scale metacognitive judgments (i.e., reliving, back in time, remembering, and realness), component processes (i.e., visual imagery, auditory imagery, language, and emotion), narrative properties (i.e., rehearsal and importance), and spatiotemporal specificity (i.e., spatial details and temporal details). AD participants showed lower general autobiographical recall than controls, and poorer reliving, travel in time, remembering, realness, visual imagery, auditory imagery, language, rehearsal, and spatial detail-a decrease that was especially pronounced for visual imagery. Yet, AD participants showed high rating for emotion and importance. Early AD seems to compromise many phenomenological features, especially visual imagery, but also seems to preserve some other features.