Asymmetric Transport Research Articles

Asymmetric carrier transport and weak localization in few layer graphene grown directly on a dielectric substrate.

Temperature-dependent electrical and magneto-transport measurements have been performed on devices composed of few layer (4L) graphene grown directly on SiO2/Si substrates using the CVD method. An intrinsic energy band-gap of 4.6 meV in 4L graphene is observed, which primarily dictates the current transport at T <50 K. Unusual temperature dependent electron-hole conduction asymmetry is observed at T >50 K, which can be explained in the framework of the defect scattering of relativistic charge carriers. Magneto-transport measurements reveal a weak localization effect sustainable till T >200 K. The coexistence of phonon mediated carrier mobility and defect induced weak localization effects in measuring devices suggests low disorder and impurity scattering.

Asymmetric carrier transport in flexible interface-type memristor enables artificial synapses with sub-femtojoule energy consumption.

Flexible and transparent artificial synapses with extremely low energy consumption have potential for use in brain-like neuromorphic electronics. However, most of the transparent materials for flexible memristive artificial synapses were reported to show picojoule-scale high energy consumption with kiloohm-scale low resistance, which limits the scalability for parallel operation. Here, we report on a flexible memristive artificial synapse based on Cs3Cu2I5 with energy consumption as low as 10.48 aJ (= 10.48 × 10-18 J) μm-2 and resistance as high as 243 MΩ for writing pulses. Interface-type resistive switching at the Schottky junction between p-type Cu3Cs2I5 and Au is verified, where migration of iodide vacancies and asymmetric carrier transport owing to the effective hole mass is three times heavier than effective electron mass are found to play critical roles in controlling the conductance, leading to high resistance. There was little difference in synaptic weight updates with high linearity and 250 states before and after bending the flexible device. Moreover, the MNIST-based recognition rate of over 90% is maintained upon bending, indicative of a promising candidate for highly efficient flexible artificial synapses.

Micrometer-scale transient ion transport for real-time pH assay in living rat brains.

Ion transport has been widely used for various applications such as sensing, desalination and energy conversion; however, nearly all applications are based on steady-state ion transport. Herein, we for the first time demonstrate the capability of transient ion transport for in vivo sensing with both high spatial (∼μm) and temporal (∼ms) resolution by using pH as the model target. Transient ion transport behavior (i.e., time-dependent ion current change) was observed by applying high-frequency pulse potential. Importantly, we proposed the ion distribution transient model for this time-dependent ion transport behavior. With this model, the temporal resolution of the as-developed pH microsensor based on ion current was improved to the ms level, thus satisfying the requirement of neurochemical recording. Moreover, our microsensor features good reproducibility, selectivity, and reversibility, and can thus real-time monitor the pH change in living rat brains. This study demonstrates the first example of in vivo sensing based on ion transport, opening a new way to neurochemical monitoring with ultrahigh spatiotemporal resolution. This study is also helpful to understand the transient process of asymmetric ion transport.

Dual-gated mono-bilayer graphene junctions.

A lateral junction with an atomically sharp interface is extensively studied in fundamental research and plays a key role in the development of electronics, photonics and optoelectronics. Here, we demonstrate an electrically tunable lateral junction at atomically sharp interfaces between dual-gated mono- and bilayer graphene. The transport properties of the mono–bilayer graphene interface are systematically investigated with Ids–Vds curves and transfer curves, which are measured with bias voltage Vds applied in opposite directions across the asymmetric mono–bilayer interface. Nearly 30% difference between the output Ids–Vds curves of graphene channels measured at opposite Vds directions is observed. Furthermore, the measured transfer curves confirm that the conductance difference of graphene channels greatly depends on the doping level, which is determined by dual-gating. The Vds direction dependent conductance difference indicates the existence of a gate tunable junction in the mono–bilayer graphene channel, due to different band structures of monolayer graphene with zero bandgap and bilayer graphene with a bandgap opened by dual-gating. Simulation of the Ids–Vds curves based on a new numerical model validates the gate tunable junction at the mono–bilayer graphene interface from another point of view. The dual-gated mono–bilayer graphene junction and new protocol for Ids–Vds curve simulation pave a possible way for functional applications of graphene in next-generation electronics.

Improved hydrogen separation performance of asymmetric oxygen transport membranes by grooving in the porous support layer

Hydrogen separation through oxygen transport membranes (OTMs) has attracted much attention. Asymmetric membranes with thin dense layers provide low bulk diffusion resistances and high overall hydrogen separation performances. However, the resistance in the porous support layer (PSL) limits the overall separation performance significantly. Engineering the structure of the PSL is an appropriate way to enable fast gas transport and increase the separation performance. There is no relevant research on studying the influence of the PSL on hydrogen separation performance so far. Herein, we prepared Ce0.85Sm0.15O1.925 – Sm0.6Sr0.4Cr0.3Fe0.7O3-δ (SDC-SSCF) asymmetric membranes with straight grooves in PSL by tape-casting and laser grooving. A ~30% improvement in the hydrogen separation rate was achieved by grooving in the PSLs. It indicates that the grooves may reduce the concentration polarization resistance in PSL for the hydrogen separation process. This work provides a straight evidence on optimizing the structures of PSL for improving the hydrogen separation performance of the membrane reactors.

Rectified Ion Transport in Ultra‐thin Membrane Governed by Outer Membrane Electric Double Layer

Summary of main observation and conclusionThe outstanding combination of selectivity and permeability observed in ultra‐thin nanoporous membranes attracts broad interest from both fundamental research and practical application aspects. It is reported that the asymmetrical ion transport can be realized through the modification of polyelectrolytes on the outer membranes surface. However, the related mechanisms are still unclear which hinders their applications. Herein, we systematically investigate the origin of the ion current rectification in heterogeneously charged ultra‐thin nanopores. The calculated results based on the continuity model suggest that, the ion transport across the ultra‐thin membrane is dominated by the charge on the outer membrane surface rather than the pore wall. The overlap of electric double layer outside the pore entrance is essential for the ion asymmetric transport. And it accordingly results in the fact that the ion concentration enrichment and depletion effect occurring outside the nanopore orifices governs the high and low ionic conductance states under the applied bias. These features can be regulated by the membrane surface state, which is truly attractive because the surfaces of the outer membrane can be easily modified by experimental approaches. These findings provide the renew inspiration for the design of high‐performance 2D nanofluidic devices.

Voltage-Dependent Transport of Neutral Solutes through Nanopores: A Molecular View.

The permeation of (neutral) molecules through nanopores in the presence of external voltages depends on several factors including pore electrostatics, electrophoretic force, and electro-osmotic drag. In earlier single-channel electrophysiology experiments, voltage-dependent asymmetric transport of neutral α-cyclodextrin (α-CD) molecules through the biological nanopore ΔCymA was observed. The voltage-dependent ion-associated flow of water, the so-called electro-osmotic flow, has been suggested to be the key factor behind the observed asymmetric behavior. The influence of pore electrostatics and electrophoretic force and their interplay with the electro-osmotic drag with varying buffers and voltages has not yet been analyzed at the molecular level. Hence, the detailed physical mechanism behind this intriguing permeation process is in part still unclear. In the present study, we have performed 36 μs all-atom free energy calculations by combining applied-field molecular dynamics simulations with metadynamics techniques. The influence of several ionic conditions as well as external voltages on the permeation of α-CD molecules across the ΔCymA pore has been investigated. To decipher the thermodynamic and kinetic details, the lowest energy paths and the permeation times for α-CD translocation have been estimated. In the presence of KCl or MgCl2 salts, the charge of the cations is found to control the direction and magnitude of the electro-osmotic flow, which in turn strongly affects α-CD permeation. Overall, the present findings significantly improve the fundamental understanding of the voltage-dependent transport of neutral solutes across nanopores.

Quasi-Stable Salt Gradient and Resistive Switching in Solid-State Nanopores.

Understanding and control of ion transport in a fluidic channel is of crucial importance for iontronics. The present study reports on quasi-stable ionic current characteristics in a SiNx nanopore under a salinity gradient. An intriguing interplay between electro-osmotic flow and local ion density distributions in a solid-state pore is found to induce highly asymmetric ion transport to negative differential resistance behavior under a 100-fold difference in the cross-membrane salt concentrations. Meanwhile, a subtle change in the salinity gradient profile led to observations of resistive switching. This peculiar characteristic was suggested to stem from quasi-stable local ion density around the channel that can be switched between two distinct states via the electro-osmotic flow under voltage control. The present findings may be useful for neuromorphic devices based on micro- and nanofluidic channels.

Asymmetric transport costs and welfare implications through a firm-delocation effect

PurposeWith the use of a two-region monopolistically competitive model, the paper primarly studies how unilateral changes in a country's intra-regional and/or inter-national transport costs affect its own and its trading partner's welfare. Moreover, by considering a three-region monopolistically competitive model that consists of an external region and two integrated regions, with the one having a location advantage with respect to the external market, the paper studies how within-country asymmetries in transport costs affect trading partner's welfare.Design/methodology/approachThis paper examines how investments in the infrastructure affect welfare in the home country and in its trading partner by primarily using a model with direction-specific intra-regional and inter-national trade costs. Moreover, it focuses on the within-country asymmetries in transportation costs and their impacts on trading partners' welfare.FindingsThe first model shows that a unilateral reduction in a country's transport costs is beneficial for its domestic firms, while it hurts firms located in its trading partner country. Other findings show that an equal bilateral reduction in inter-national transport costs is a Pareto improvement, since it is beneficial for both countries. The second model shows that a reduction in intra-regional transport costs benefits the two integrated regions, while it has no impact on the welfare of the external region.Originality/valueTwo monopolistically competitive models are considered, in order to study how investments in the infrastructure affect welfare in the home country and in its trading partner. Interestingly, the models sheds light on an important mechanism, that of firm-delocation effect.

Selective Proton Transport for Hydrogen Production Using Graphene Oxide Membranes.

Graphene oxide has shown exceptional properties in terms of water permeability and filtration characteristics. Here the suitability of graphene oxide membranes for the spatial separation of hydronium and hydroxide ions after photocatalytic water splitting is demonstrated. Instead of relying on classical size exclusion by adjusting the membrane laminates' interlayer spacings, nonmodified graphene oxide is used to exploit the presence of its natural functional groups and surface charges for filtration. Despite a significantly larger interlayer spacing inside the membrane compared with the size of the hydrated radii of the ions, highly asymmetric transport behavior and a 6 times higher mobility for hydronium than for hydroxide are observed. DFT simulations reveal that hydroxide ions are more prone to interact and stick to the functional groups of graphene oxide, while diffusion of hydronium ions through the membrane is less impeded and aligns well with the concept of the Grotthuss mechanism.

Asymmetric transport in boron intratube p-i-n junction via gas storage for diode applications

Boron nanotubes (BNTs) possess higher conductivities than carbon nanotubes (CNTs), making them potential candidates for nanoscale p-i-n diode applications. Herein, we designed a novel boron intratube p-i-n junction via gas storage, by using ab initio quantum transport simulations. NO and NH3 are the optimal oxide and hydride to inject holes and electrons into (5,5) buckled triangular BNT (BT-BNT), respectively. The device performance in (5,5) BT-BNT FET indicates that the gas storage can rationally change the majority carrier type and concentration, by which (5,5) BT-BNT-based p-i-n junction with large negative rectification can be constructed. We further investigated the dependence of asymmetric transport on the intrinsic region length in the formed p-i-n junction. It is found that the insertion of intrinsic region can act as a buffer layer to reduce the carrier concentration difference on p-type and n-type regions, thus weakening the transport asymmetry. A short intrinsic region with length of 6.22 Å, i.e., n = 2, contributes to improve the rectifying ratio. Our results demonstrate the significance of gas storage combined with the intrinsic region in the formation of p-i-n junction for diode applications based on one-dimensional nanotubes.

Phonon manipulation with valley-Hall junctions

In this work, we investigate experimentally the existence of in-plane valley Hall edge states in hexagonal lattices with relaxed space inversion symmetry and we exploit them to realize non-trivial backscattering-free interfaces. We propose special tessellations of lattice domains in which multiple non-trivial domain walls coalesce to form junctions, and we study how guided waves behave when they impinge on such junctions. We show that, through a proper selection of the interface types and orientations, it is possible to achieve junctions with different and exotic wave manipulation capabilities. Specifically, we discuss two applications. The first is a direction-selective splitter, which endows its host lattice with asymmetric wave transport characteristics. The second is a signal delayer that is realized by embedding in the lattice a non-trivial waveguide loop, along which the energy can be temporarily trapped and periodically released. These junctions can serve as building blocks for a new structural logic paradigm enabled by topological mechanics.

Two- and Three-Dimensional Tracking of MFA2 mRNA Molecules in Mating Yeast.

Intracellular mRNA transport contributes to the spatio-temporal regulation of mRNA function and localized translation. In the budding yeast, Saccharomyces cerevisiae, asymmetric mRNA transport localizes ~30 specific mRNAs including those encoding polarity and secretion factors, to the bud tip. The underlying process involves RNA-binding proteins (RBPs), molecular motors, processing bodies (PBs), and the actin cytoskeleton. Recently, pheromone a-factor expression in mating yeast was discovered to depend on proper localization of its mRNA, MFA2 mRNAs in conjunction with PBs cluster at the shmoo tip to form “mating bodies”, from which a-factor is locally expressed. The mechanism ensuring the correct targeting of mRNA to the shmoo tip is poorly understood. Here we analyzed the kinetics and trajectories of MFA2 mRNA transport in living, alpha-factor treated yeast. Two- (2D) and three-dimensional (3D) analyses allowed us to reconstruct the granule tracks and estimate granule velocities. Tracking analysis of single MFA2 mRNA granules, labeled using a fluorescent aptamer system, demonstrated three types movement: vibrational, oscillatory and translocational. The mRNA granule transport was complex; a granule could change its movement behavior and composition during its journey to the shmoo. Processing body assembly and the actin-based motor, Myo4p, were involved in movement of MFA2 mRNA to the shmoo, but neither was required, indicating that multiple mechanisms for translocation were at play. Our visualization studies present a dynamic view of the localization mechanism in shmoo-bearing cells.

The Role of Mitochondria in Drug-Induced Kidney Injury.

The kidneys utilize roughly 10% of the body’s oxygen supply to produce the energy required for accomplishing their primary function: the regulation of body fluid composition through secreting, filtering, and reabsorbing metabolites and nutrients. To ensure an adequate ATP supply, the kidneys are particularly enriched in mitochondria, having the second highest mitochondrial content and thus oxygen consumption of our body. The bulk of the ATP generated in the kidneys is consumed to move solutes toward (reabsorption) or from (secretion) the peritubular capillaries through the concerted action of an array of ATP-binding cassette (ABC) pumps and transporters. ABC pumps function upon direct ATP hydrolysis. Transporters are driven by the ion electrochemical gradients and the membrane potential generated by the asymmetric transport of ions across the plasma membrane mediated by the ATPase pumps. Some of these transporters, namely the polyspecific organic anion transporters (OATs), the organic anion transporting polypeptides (OATPs), and the organic cation transporters (OCTs) are highly expressed on the proximal tubular cell membranes and happen to also transport drugs whose levels in the proximal tubular cells can rapidly rise, thereby damaging the mitochondria and resulting in cell death and kidney injury. Drug-induced kidney injury (DIKI) is a growing public health concern and a major cause of drug attrition in drug development and post-marketing approval. As part of the article collection “Mitochondria in Renal Health and Disease,” here, we provide a critical overview of the main molecular mechanisms underlying the mitochondrial damage caused by drugs inducing nephrotoxicity.

Function-related asymmetry of the specific cardiolipin binding sites on the mitochondrial ADP/ATP carrier

The ADP/ATP carrier (AAC) transports matrix ATP and cytosolic ADP across the inner mitochondrial membrane (IMM). It is well known that cardiolipin (CL) plays an important role in regulating the function of AAC, yet the underlying mechanism still remains elusive. AAC is composed of three homologous domains, and three specific CL binding sites are located at the domain-domain interfaces near the matrix side. Here we report an in-depth investigation on the dynamic properties of the bound CL within the three specific sites through all-atom molecular dynamics simulations of up to 13 μs in total. Our results highlight the importance of the basic and polar residues in CL binding. The basic residues from the linker helix and/or the [Y/W/F][K/R]G motif enable the bound CL to form an intra-domain binding mode, and the canonical inter-domain binding mode only forms when these basic residues are occupied by an additional phospholipid. Of special significance, differences in the basic and polar residues lead to remarkable asymmetry among the three specific CL binding sites. We found that the bound CL at the interface of domains 2 and 3 predominantly adopts inter-domain binding mode, while CLs at the other two sites have much more intra-domain populations. This is consistent with the asymmetric crystal structure of the matrix state (m-state) AAC which implies an asymmetric transport mechanism. The dynamic equilibrium between the inter-domain and intra-domain binding modes observed in our simulations could be highly important for the bound CLs to adapt to the movements during state transitions.

Topological and flat-band states induced by hybridized linear interactions in one-dimensional photonic lattices

We report on a study of a one-dimensional linear photonic lattice hosting, simultaneously, fundamental and dipolar modes at every site. We show how, thanks to the interaction between the different orbital modes, this minimal model exhibits rich transport and topological properties. By varying the detuning coefficient we find a regime where bands become flatter (with reduced transport) and, a second regime, where both bands connect on at a gap-closing transition (with enhanced transport). We detect an asymmetric transport due to the asymmetric inter-mode coupling and a linear energy exchange mechanism between modes. Further analysis show that the bands have a topological transition with a non-trivial Zak phase which leads to the appeareance of edge states in a finite system. Finally, for zero detuning, we found a symmetric condition for coupling constants, where the linear spectrum becomes completely flat, with states fully localized in space occupying only two lattice sites.

Impact of carrier transport on the performance of QD lasers on silicon: a drift-diffusion approach

The operation of quantum dot lasers epitaxially grown on silicon is investigated through a quantum-corrected Poisson-drift-diffusion model. This in-house developed simulation framework completes the traditional rate equation approach, which models the intersubband transitions involved into simultaneous ground-state and excited-state lasing, with a physics-based description of carrier transport and electrostatic effects. The code is applied to look into some of the most relevant mechanisms affecting the lasing operation. We analyze the impact of threading dislocations on non-radiative recombination and laser threshold current. We demonstrate that asymmetric carrier transport in the barrier explains the ground-state power quenching above the excited-state lasing threshold. Finally, we study p-type modulation doping and its benefits/contraindications. The observation of an optimum doping level, minimizing the ground-state lasing threshold current, stems from the reduction of the electron density, which counteracts the benefits from the expected increase of the hole density. This reduction is due to electrostatic effects hindering electron injection.

Electroosmosis-Driven Nanofluidic Diodes.

Fundamental understanding of ion transport in a fluidic channel is of critical importance for realizing iontronics. Here we report on asymmetric ion transport in a low thickness-to-diameter aspect ratio nanopore. Under uniform salt concentration conditions, the cross-pore ionic current showed ohmic characteristics with no bias polarity dependence. In stark contrast, despite the weak ion selectivity expected for the relatively large nanopores employed, we observed diode-like behavior when a salt gradient was imposed across the thin membrane. This unexpected result was attributed to the electroosmotic flow that served to modulate the access resistance through dragging the condensed ions into or out of the nanopore orifices. The simple mechanism was also revealed to be effective in fluidic channels of various size from micro- to nanoscale enabling rectification of the property engineering by the pore geometries. The present findings allow for novel designs of artificial ion channel building blocks.

Efficient photovoltaic effect in graphene/h-BN/silicon heterostructure self-powered photodetector

Graphene (Gr)/Si-based optoelectronic devices have attracted a lot of academic attention due to the simpler fabrication processes, low costs, and higher performance of their two-dimensional (2D)/three-dimensional (3D) hybrid interfaces in Schottky junction that promotes electron-hole separation. However, due to the built-in potential of Gr/Si as a photodetector, the Iph /Idark ratio is often hindered near zero-bias at relatively low illumination intensity. This is a major drawback in self-powered photodetectors. In this study, we have demonstrated a self-powered van der Waals heterostructure photodetector in the visible range using a Gr/hexagonal boron nitride (h-BN)/Si structure and clarified that the thin h-BN insertion can engineer asymmetric carrier transport and avoid interlayer coupling at the interface. The dark current was able to be suppressed by inserting an h-BN insulator layer, while maintaining the photocurrent with minimal decrease at near zero-bias. As a result, the normalized photocurrent-to-dark ratio (NPDR) is improved more than 104 times. Also, both Iph/Idark ratio and detectivity, increase by more than 104 times at −0.03 V drain voltage. The proposed Gr/h-BN/Si heterostructure is able to contribute to the introduction of next-generation photodetectors and photovoltaic devices based on graphene or silicon.

Potential Vorticity Mixing and Rapid Intensification in the Numerically Simulated Supertyphoon Haiyan (2013)

AbstractThe inner-core dynamics of Supertyphoon Haiyan (2013) undergoing rapid intensification (RI) are studied with a 2-km-resolution cloud-resolving model simulation. The potential vorticity (PV) field in the simulated storm reveals an elliptical and polygonal-shaped eyewall at the low and middle levels during RI onset. The PV budget analysis confirms the importance of PV mixing at this stage, that is, the asymmetric transport of diabatically generated PV to the storm center from the eyewall and the ejection of PV filaments outside the eyewall. We employ a piecewise PV inversion (PPVI) and an omega equation to interpret the model results in balanced dynamics. The omega equation diagnosis suggests eye dynamical warming is associated with the PV mixing. The PPVI indicates that PV mixing accounts for about 50% of the central pressure fall during RI onset. The decrease of central pressure enhances the boundary layer (BL) inflow. The BL inflow leads to contraction of the radius of the maximum tangential wind (RMW) and the formation of a symmetric convective PV tower inside the RMW. The eye in the later stage of the RI is warmed by the subsidence associated with the convective PV towers. The results suggest that the pressure change associated with PV mixing, the increase of the symmetric BL radial inflow, and the development of a symmetric convective PV tower are the essential collaborating dynamics for RI. An experiment with 500-m resolution shows that the convergence of BL inflow can lead to an updraft magnitude of 20 m s−1and to a convective PV tower with a peak value of 200 PVU (1 PVU = 10−6K kg−1m2s−1).