SESSION TITLE: Wednesday Abstract Posters SESSION TYPE: Original Investigation Posters PRESENTED ON: 10/23/2019 09:45 AM - 10:45 AM PURPOSE: Sleep disturbances and night-time symptoms are associated with the level of control of asthma symptoms and quality of life. Main aim: Validate the SJQ questionnaire into Spanish (Table 1). Secondary aim: assess quality of sleep in asthmatic patients using the SJQ and the Medical Outcomes Study (MOS) sleep scale. METHODS: A multicentric prospective study with an intervention group of asthmatic patients and a control group. A total of 90 cases and 90 controls were included. 1)Collection of demographic and asthma data, and sleep questionnaires (SJQ and MOS) during three successive visits (visit 1 [V1], visit 2 [V2] and visit 3 [V3]). Each patient consecutively recruited was matched with a control with similar demographic characteristics. 2) Inclusion criteria: asthmatic individuals of both sexes with stable asthma without exacerbation in the previous month, age 17-80 years 3) Exclusion criteria: severe comorbidity, shift work, patients with young children, prostatic disorder, treatment with benzodiazepines or recent obstructive sleep apnoea (OSA) with continuous positive airway pressure (CPAP) 4) Administration of the SJQ during the three successive visits to analyse the metric properties of the questionnaire (internal consistency, validity criteria, construct validity and sensitivity to change). RESULTS: A total of 90 cases and 90 controls were included. The test-retest of SJQ between V1 and V2 in the 90 cases showed temporary stability with an intraclass correlation coefficient of 0.847. Patients who had exacerbation of asthma between V2 and V3 had higher scores in SJQ (worse quality of sleep) at V3 than V2 (mean score: 9 at V2 and 11.8 at V3), with a correlation of 0.390, which shows the sensitivity to change of the test. A good correlation between the two measurement scales (SJQ and MOS) was observed at V1, with a regression index of 0.696 (Figure 1). Likewise, the SJQ score between cases and controls during V1 showed significant differences in quality of sleep in both groups (mean score 3.72 for controls and 7.22 for cases). No statistically significant differences were found in quality of sleep depending of the severity of asthma but statistically significant differences werw observed according to the Asthma Control Test (ACT 24 points: mean SJQ score 3.40; p=0.002). The overall quality of sleep of our patients was good, with a SJQ score of 5.65 at V1 and 7.45 at V2. CONCLUSIONS: The Sleep Jenkins questionnaire showed temporary stability in the test-retest, sensitivity to change and validity criteria (compared to the MOS scale). SJQ found statistically significant differences in quality of sleep depending on the level of control of asthma symptoms CLINICAL IMPLICATIONS: The Sleep Jenkins Questionnaire is useful to evaluate quality of sleep among patients with asthma. DISCLOSURES: No relevant relationships by Francisco Javier Callejas Gonzalez, source=Web Response no disclosure on file for Federico Fiorentino; No relevant relationships by Marta GENOVÉS CRESPO, source=Web Response No relevant relationships by Abel Pallarés-Sanmartín, source=Web Response