Aspects Of Process Research Articles

Practitioner Review: Continuity of mental health care from childhood to adulthood for youths with ADHD-who, how and when?

Many youths with attention-deficit/hyperactivity disorder (ADHD) experience significant long-term impairment and may develop concurrent mental and somatic health difficulties as adults. This is associated with burden and costs for the individual and society which could be prevented through continued support in youth. Yet, only few young people transition to adult mental health services for ongoing care in different countries worldwide. We provide an overview on current transition practices, highlighting the gaps in knowledge and the barriers to effective service transitioning, while considering the large geographical variation in available guidelines and service provision. For ease of use, this review is organized in a question-and-answer format covering different aspects of the transition process and considering both service users' and clinicians' perspectives. Consensus is needed to identify those that require continued care, the optimal timing to arrange transition, and the most suitable services. Finally, we discuss cost-effectiveness of transition practices, consider examples of best practice, and propose recommendations on how to improve transitional care, including the importance of service users' input into transition planning.

Perception and adaptation of receptive prosody in autistic adolescents

A fundamental aspect of language processing is inferring others’ minds from subtle variations in speech. The same word or sentence can often convey different meanings depending on its tempo, timing, and intonation–features often referred to as prosody. Although autistic children and adults are known to experience difficulty in making such inferences, the science remains unclear as to why. We hypothesize that detail-oriented perception in autism may interfere with the inference process if it lacks the adaptivity required to cope with the variability ubiquitous in human speech. Using a novel prosodic continuum that shifts the sentence meaning gradiently from a statement (e.g., “It’s raining”) to a question (e.g., “It’s raining?”), we have investigated the perception and adaptation of receptive prosody in autistic adolescents and two groups of non-autistic controls. Autistic adolescents showed attenuated adaptivity in categorizing prosody, whereas they were equivalent to controls in terms of discrimination accuracy. Combined with recent findings in segmental (e.g., phoneme) recognition, the current results provide the basis for an emerging research framework for attenuated flexibility and reduced influence of contextual feedback as a possible source of deficits that hinder linguistic and social communication in autism.

Value of improved nursing measures and enhanced nursing management to reduce the occurrence of adverse events in pediatric infusion.

Intravenous infusion is a common method of drug administration in clinical practice. Errors in any aspect of the infusion process, from the verification of medical orders, preparation of the drug solution, to infusion by nursing staff, may cause adverse infusion events. To analyzed the value of improving nursing measures and enhancing nursing management to reduce the occurrence of adverse events in pediatric infusion. The clinical data of 130 children who received an infusion in the pediatric department of our hospital from May 2020 to May 2021 were analyzed and divided into two groups according to the differences in nursing measures and nursing management: 65 patients in the control group received conventional nursing and nursing management interventions, while 65 patients in the observation group received improved nursing measure interventions and enhanced nursing management. The occurrence of adverse events, compliance of children, satisfaction of children's families, and complaints regarding the transfusion treatment were recorded in both groups. The incidence of fluid extravasation and infusion set dislodgement in the observation group were 3.08% and 1.54%, respectively, which were significantly lower than 12.31% and 13.85% in the control group (P < 0.05), while repeated punctures and medication addition errors in the observation group were 3.08% and 0.00%, respectively, which were lower than 9.23% and 3.08% in the control group, but there was no significant difference (P > 0.05). The compliance rate of children in the observation group was 98.46% (64/65), which was significantly higher than 87.69% (57/65) in the control group, and the satisfaction rate of children's families was 96.92% (63/65), which was significantly higher than 86.15% (56/65) in the control group (P < 0.05). The observation group did not receive any complaints from the child's family, whereas the control group received four complaints, two of which were due to the crying of the child caused by repeated punctures, one due to the poor attitude of the nurse, and one due to medication addition errors, with a cumulative complaint rate of 6.15%. The cumulative complaint rate of the observation group was significantly lower than that of the control group (P < 0.05). Improving nursing measures and enhancing nursing management can reduce the incidence of fluid extravasation and infusion set dislodgement in pediatric patients, improve children's compliance and satisfaction of their families, and reduce family complaints.

Scalable interconnection using a superconducting flux qubit

Superconducting quantum computers are rapidly reaching scales where bottlenecks to scaling arise from the practical aspects of the fabrication process. To improve quantum computer performance, implementation technology that guarantees the scalability of the number of qubits is essential. Increasing the degrees of freedom in routing by 2.5-dimensional implementation is important for realizing circuit scalability. We report an implementation technology to overcome the scaling bottlenecks using a reliable connection qubit with a demonstration of quantum annealing. The method comprises interconnection based on quantum annealing using a superconducting flux qubit, precise coupling status control, and flip-chip bonding. We perform experiments and simulations with a proof-of-concept demonstration of qubit coupling via interconnection using a flux qubit. The coupling status is strictly controllable by quantum annealing. A low-temperature flip-chip bonding technology is introduced for the 2.5-dimensional interconnection. The superconducting flux qubit, formed across two different chips via bumps, is demonstrated for the first time to show a state transition like that in a conventional qubit. The quantum annealing flux qubit and flip-chip bonding enable new interconnections between qubits. A perspective on the possibility of applying this technology to the connection between gate-type qubits is described.

Identity Formation and Acculturation in Smith’s White Teeth and Adichie’s Americanah: Critiquing the Immigrants’ Generational Experiences

This paper examines the relationship between identity formation and acculturation in Zadie Smith’s White Teeth and Chimamanda Ngozi Adichie’s Americanah by unpacking the behaviours and experiences of the first-generation immigrant characters Samad (White Teeth) and Ifemelu (Americanah), and the second-generation immigrant characters Millat (White Teeth) and Dike (Americanah). These two generations of immigrants represent two-fold aspects of acculturation process. For the first-generation immigrants, integration serves as a vital acculturation strategy. However, the second-generation immigrants experience an in-between condition because of their weaker ties to their home country and culture, coupled with the experiences of discrimination in their new cultural environment. To analyze these themes of acculturation within the novels, this study integrates John W. Berry's and David L. Sam's concepts of acculturation, acculturation strategies, and acculturation stress. Additionally, Stuart Hall's concept of cultural identity is borrowed to elucidate the notions of culture and identity within the narratives. Furthermore, Homi K. Bhabha’s notion of hybridity is employed to examine the in-between state of second-generation immigrants in the novels. By highlighting the connection between identity formation and acculturation in the novels, this study underscores the importance of understanding the complexities of identity formation and acculturation among immigrants across generations in diverse cultural contexts.

DISCUSSIONS ABOUT THE ESSENCE AND CONTENT OF THE CONCEPT OF “PEDAGOGICAL COMPETENCE”

Summarizing what has been said, it is noted that concepts such as “pedagogical delicacy”, “pedagogical skill”, “pedagogical culture”, “pedagogical professionalism”, “pedagogical qualities”, etc., no matter how similar and very close in essence, depending on different complex aspects of the pedagogical process, as well as from the concepts of “pedagogical competency” and “pedagogical competence” have different contents. Their views on pedagogical competence can be summarized as follows: The competence of a teacher is manifested in his high moral qualities, national and universal values, deep knowledge, and perfect knowledge of his specialty and in teaching.

Design and Control of the Natural Frequency of Brake Discs in the Aspect of the Gray Cast Iron Production Process

The results of research on the influence of the chemical composition of cast iron and its potential changes in the production cycle on the elastic properties and the correctness of numerical simulations of the natural frequency of ventilated brake discs are presented. The tests were carried out for three grades of gray cast iron with flake graphite with a eutectic saturation coefficient ranging from 0.88 to 1.01. A quantitative metallographic assessment of the pearlitic cast iron matrix and graphite precipitates was carried out, and the hardness and compressive/tensile strength of individual cast iron grades were determined, taking into account the limit contents of the alloying elements. Next, ultrasonic tests were performed, and the elastic properties of cast iron were determined. Based on the obtained data, a numerical modal analysis of brake discs was performed, the results of which were compared with the actual values of an FRF frequency analysis. The error of the computer simulations was estimated at approx. 1%, and it was found that the accuracy of the calculations of the first natural frequency did not depend on the dimensions (size) of the discs and the chemical composition of the cast iron from which they were cast. The functional relationships between the chemical composition of cast iron, its strength and elasticity and the first natural frequency of the disc vibrations were determined, and a database of the material parameters of the produced cast iron grades was developed. An implementation example showed the validation of the brake disc design with natural frequency prediction and demonstrated a high convergence of the experimental results with the simulated values. Using I-MR control cards, both the effectiveness of designing and predicting the natural vibrations of brake discs based on the implemented material database as well as the stability of the gray cast iron production and disc casting processes were confirmed.

Pharmacy students' process of learning of real patients in a simple first-person perspective patient simulation exercise — A qualitative analysis

IntroductionPharmacists need more insight into patients' perspectives on medicine to target their counseling and improve patient outcomes. Patient simulation exercises, where pharmacy students are asked to consume medicine-like products, have been shown to foster such understandings, although the specifics of how this occurs, in particularly, how students turn their first-person perspectives toward generalizations about real patients' lives with medicines, are not well documented.The aim was to identify central aspects of the learning process by introducing reflection questions about real patients and follow students' development during a study period. MethodsThe study was conducted with students in their 4th semester in the second year of Pharmacy Education at the University of Copenhagen who were asked to respond to free text questions in a survey instrument about their daily experiences of taking a licorice product for one week as well as answering patient reflection questions. Qualitative deductive analysis was performed by coding students' experiences according to concepts of ‘experiential learning’. Pattern identification within each concept was then inferred, as were their interrelationships. ResultsPatient reflection questions enabled students to turn their first-person perspectives toward relevant generalizations about real patients' lives with medicines, including involved psychological mechanisms and how real patient groups differ in their ability to take medicine regularly. Students who during the week faced challenges with following the required dosing scheme came to more nuanced realizations that medicine adherence requires special efforts and restricts one's daily life; hence, negative emotions were involved in the learning process. ConclusionsThe design of the simple patient simulation exercise gave rise to new types of insights into real patients' lives with medicines. Negative emotions due to interference between the requirements of the exercise and students' normal social lives, as well as commitment to the exercise, were important aspects of this process.

Sustainable rural economy and food security: An integrated approach to the circular agricultural model

The lack of resources and increasing damage are major obstacles to sustainable economic progress. Conventional farming methods, known for their energy consumption and resulting pollution, need changes. This study focuses on agriculture, an approach inspired by natural ecological cycles that aim to promote sustainable development in rural areas through efficient resource reuse. The connection between agriculture and rural economies, along with strategies for their combined advancement, is an area that requires more exploration and thorough empirical analysis. The research involves an energy analysis methodology tailored for use in regions to assess the benefits and environmental impacts of implementing circular agriculture for sustainable rural economic growth. A multi-objective decision-making approach using TOPSIS is employed to enhance agricultural policy formulation and decision-making processes. The study concludes by developing a model that considers production, processing, recycling, and socioeconomic aspects to delve into the development of circular agriculture within rural communities and propose relevant strategies. The uniqueness of this research lies in its combination of agriculture and the coordinated advancement of rural economies, which offers a fresh viewpoint and approach to sustainable farming methods and robust rural economic development. The results contribute to the circular agriculture literature body and provide practical guidance for policymakers and farmers.

Additive manufacturing and mechanical analysis of multi-material polymer parts combining thermosets and thermoplastics

Multi-material additive manufacturing (AM) represents one of the most promising solutions to target the contemporary demand for complex products with high individuality and inherent functionalities. Besides continuous advances in machinery and the available material spectrum, a substantial aspect of multi-material AM is still underrepresented: the simultaneous combination of thermosets and thermoplastic within a single AM process. A promising technology in this regard is the newly developed Fusion Jetting (FJ) process. This investigation focuses on the combination of acrylate-based photopolymers (thermoset) and thermoplastic polyurethane (TPU) with FJ. Tensile specimens are built with strategic variations of the process parameters and experimentally analyzed to derive beneficial processing conditions. A proof of concept is delivered by demonstrating a significant increase in Young’s modulus of TPU specimens from approximately 65 to 160 MPa through integration of photopolymer reinforcements. Further experiments regarding variable layer heights and laser powers identify an optimum layer height of 100 µm along with a tolerable laser power of 15 W for maximum mechanical properties. An overall challenging aspect of the FJ process is the presence of unwanted delamination between reinforced and non-reinforced layers. The failure mode is observed during tensile testing on multiple multi-material specimens of this investigation. The origin of delamination can be correlated to the deviation of integrated reinforcements from their originally intended dimensions as well as the unwanted crystallization within reinforced layers. First, countermeasures to minimize delamination are identified, such as decreasing the rotational increment of the laser hatch orientation from 90 to 10° per layer.

Overview of the Medical Waste Management System by Health Human Resources (SDK) at the Putri Ayu Public Health Center, Jambi City in 2024

According to the Jambi City Health Service Profile in 2021-2022, Putri Ayu Health Center is one of the inpatient health centers in Jambi City which is also acontributes the largest amount of medical waste with the amount of waste is 615 kg out of a total of 7804.1 kg of medical waste from health centers in Jambi City, so it has the potential to spread disease if medical waste is not managed properly. This research uses qualitative research methods with a descriptive approach. Data was obtained from 8 informants by conducting in-depth interviews and observations in May 2023 - April 2024 using qualitative research data analysis software. In the input aspect (1) Human Resources in the quantity aspect are sufficient, while the qualifications are not appropriate because they come from general administration. (2) Facilities and infrastructure are not sufficient and if there is damage, goods will be procured and reported to envinronmental health authority. Meanwhile, in the process aspect (3) Sorting is carried out by each waste producing poly unit by labeling the type of waste, date and poly, (4) The container used at the Putri Ayu Public Health Center meets the standards of Minister of Health Regulation Number 18 of 2020 (5) Transportation is carried out more than once every 2 days by PT Anggrek (6). Storage is carried out at TPS with a time span of 2-3 days at the latest. There are still input aspects that do not comply with standards (in the case of this research, namely the quality of human resources) causing disruption to process aspects, such as less than optimal management performance in managing medical waste in the container, transport and storage processes.

Role of miRNA in Highly Pathogenic H5 Avian Influenza Virus Infection: An Emphasis on Cellular and Chicken Models

The avian influenza virus, particularly the H5N1 strain, poses a significant and ongoing threat to both human and animal health. Recent outbreaks have affected domestic and wild birds on a massive scale, raising concerns about the virus’ spread to mammals. This review focuses on the critical role of microRNAs (miRNAs) in modulating pro-inflammatory signaling pathways during the pathogenesis of influenza A virus (IAV), with an emphasis on highly pathogenic avian influenza (HPAI) H5 viral infections. Current research indicates that miRNAs play a significant role in HPAI H5 infections, influencing various aspects of the disease process. This review aims to synthesize recent findings on the impact of different miRNAs on immune function, viral cytopathogenicity, and respiratory viral replication. Understanding these mechanisms is essential for developing new therapeutic strategies to combat avian influenza and mitigate its effects on both human and animal populations.

Can geroscience be translated into healthcare?

As an introduction to this special issue on geroscience, the present work focuses on the complexity of disentangling biomolecular mechanisms of aging from biopsychosocial causes of accelerated aging. Due to this complexity, the biomolecular aging hallmarks of frailty and multimorbidity as predominant aging phenotypes in geriatrics reflect single aspects of the aging process. Apossible approach to facilitate the integration of geroscience into healthcare might be to consider aging as the dynamic ratio between damage accumulation at the molecular and cellular level and resilience as strategies that prevent or repair such damage. There is alarge body of evidence to show that geroscience has the potential to change healthcare; however, reaching aconsensus and translating the best tool to measure aging needs more research on 1)the sensitivity of biomarkers to interventions and 2)the relationship between changes in biomarkers and changes in health trajectories.

Can geroscience be translated into healthcare?

As an introduction to this special issue on geroscience, the present work focuses on the complexity of disentangling biomolecular mechanisms of aging from biopsychosocial causes of accelerated aging. Due to this complexity, the biomolecular aging hallmarks of frailty and multimorbidity as predominant aging phenotypes in geriatrics reflect single aspects of the aging process. Apossible approach to facilitate the integration of geroscience into healthcare might be to consider aging as the dynamic ratio between damage accumulation at the molecular and cellular level and resilience as strategies that prevent or repair such damage. There is alarge body of evidence to show that geroscience has the potential to change healthcare; however, reaching aconsensus and translating the best tool to measure aging needs more research on 1)the sensitivity of biomarkers to interventions and 2)the relationship between changes in biomarkers and changes in health trajectories.

Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.

De novo variants in the Cytoplasmic FMR1-interacting protein 2 (CYFIP2) have been repeatedly associated with neurodevelopmental disorders and epilepsy, underscoring its critical role in brain development and function. While CYFIP2's role in regulating actin polymerization as part of the WAVE regulatory complex (WRC) is well-established, its additional molecular functions remain relatively unexplored. In this study, we performed unbiased quantitative proteomic analysis, revealing 278 differentially expressed proteins (DEPs) in the forebrain of Cyfip2 knock-out embryonic mice compared to wild-type mice. Unexpectedly, these DEPs, in conjunction with previously identified CYFIP2 brain interactors, included not only other WRC components but also numerous proteins associated with membraneless organelles (MLOs) involved in mRNA processing and translation within cells, including the nucleolus, stress granules, and processing bodies. Additionally, single-cell transcriptomic analysis of the Cyfip2 knock-out forebrain revealed gene expression changes linked to cellular stress responses and MLOs. We also observed morphological changes in MLOs in Cyfip2 knock-out brains and CYFIP2 knock-down cells under basal and stress conditions. Lastly, we demonstrated that CYFIP2 knock-down in cells, potentially through WRC-dependent actin regulation, suppressed the phosphorylation levels of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2α), thereby enhancing protein synthesis. These results suggest a physical and functional connection between CYFIP2 and various MLO proteins and also extend CYFIP2's role within the WRC from actin regulation to influencing eIF2α phosphorylation and protein synthesis. With these dual functions, CYFIP2 may fine-tune the balance between MLO formation/dynamics and protein synthesis, a crucial aspect of proper mRNA processing and translation.

A Simulation Study on Sieving as a Powder Deposition Method in Powder Bed Fusion Processes

Powder deposition of even and homogeneous layers is a major aspect of every powder bed fusion process. Powder sieving is commonly performed to powder batches outside of the PBF machine, prior to the part manufacturing stage. In this work, sieving is examined as a method of powder deposition rather than a method to solely filter out agglomerates and oversized particles. Initially, a DEM powder model that has been validated experimentally is implemented, and the sieving process is modelled. The sieving process is optimized in order to maximize mass flow, duration of its linear stage and total mass sieved during linearity. For this, a Taguchi design of experiments with subsequent analysis of variance is deployed, proving that the larger the initial powder loaded in the sieve, the larger the sieve stimulation necessary, both in terms of oscillating frequency and amplitude. The sieve’s aperture shape is also evaluated, proving that the more sides the canonical polygon has, the less the mass flow per aperture for the same maximum passing particle size. Then, the quality of the layer produced via controlled sieving is examined via certain layer quality criteria, such as the surface roughness, layer thickness deviation, surface coverage ratio and packing density. The findings prove that controlled sieving can outperform powder deposition via a non-vibrated doctor blade recoater, both in terms of layer surface quality and duration of layer deposition, as proven by surface skewness and kurtosis evaluation.

Role of miRNA in Highly Pathogenic H5 Avian Influenza Virus Infection: An Emphasis on Cellular and Chicken Models

The avian influenza virus, particularly the H5N1 strain, poses a significant and ongoing threat to both human and animal health. Recent outbreaks have affected domestic and wild birds on a massive scale, raising concerns about the virus’ spread to mammals. This review focuses on the critical role of microRNAs (miRNAs) in modulating pro-inflammatory signaling pathways during the pathogenesis of influenza A virus (IAV), with an emphasis on highly pathogenic avian influenza (HPAI) H5 viral infections. Current research indicates that miRNAs play a significant role in HPAI H5 infections, influencing various aspects of the disease process. This review aims to synthesize recent findings on the impact of different miRNAs on immune function, viral cytopathogenicity, and respiratory viral replication. Understanding these mechanisms is essential for developing new therapeutic strategies to combat avian influenza and mitigate its effects on both human and animal populations.

Microstructure evolvement and wear properties of Ni60-based coating by ultrasonic power-assisted laser cladding

Ultrasonic vibration is known to cause significant refinement of microstructure, the effect of ultrasonic power on grain size, grain orientation and Schmid factor by laser cladding in the Ni60/WC composite coating was studied systematically. Meanwhile, the effect of microstructure on wear properties and hardness was elucidated. The results show that the performance of the cladding layer is the best when the ultrasonic power is 600 W, which is due to the combined effect of ultrasonic cavitation and acoustic flow. The average grain diameter is refined from 28.36 μm to 23.02 μm, and the refinement range is 18.9%. The formation of low Angle grain boundaries (LAGBs) is promoted by ultrasound, and the dislocation density is increased. The texture strength of the coating is distributed over {100}, {110} and {111} surfaces, and the strength decreases from 12.307 to 5.447 The microhardness is increased by 16% (from 768.85HV1 to 896.95HV1), the wear mechanism gradually from adhesive to abrasive wear and the average friction coefficient decreases from 0.47 to 0.216 with the increase of ultrasonic power, which improve the wear resistance of the coatings. Based on the understanding of microstructure evolvement, the grain refinement mechanism effected by ultrasonic power was explained from the aspect of cavitation processes.

“¡Eso no nos representa!” Historia, contexto(s) y representación en el Monumento Nacional a la Memoria de las Víctimas del Holocausto Judío de Buenos Aires, Argentina

Objective/Context: In the field of Holocaust studies, the Latin American experience has occupied a liminal space. Even when the global character assumed by its forms of remembrance is widely accepted, little attention has been paid to the national cases of this region. This paper deals with a specific national case through the construction record of the National Monument to the Victims of the Jewish Holocaust, located in the city of Buenos Aires, Argentina. The present research reveals the legal and administrative process that accompanied its gestation, the recognition of the actors that intervened throughout the period, and, finally, the character and debates that the architecture of the pantheon provoked. This cycle, which lasted a little more than two decades, allows us to qualify the meaning of the global character of Holocaust memory by considering how this experience was redefined in a national context. Methodology: For this research, qualitative techniques are used in the analysis of the legislative and patrimonial records, journalistic sources, interviews with involved actors, and a documentary film called “Monument,” which aims to give an account of the history of its construction and the representational matrix of that memorial. Originality: Although there have been, in recent years, some works that addressed the memory of the Holocaust in Argentina, they focused on various cultural media: literature, film, and testimonial narratives. This paper addresses an object whose materiality is different—monumental—and which was conceived as a public policy of commemorative character. The analysis of the construction of this memorial pantheon allows recognition of how the transnational dimensions of Holocaust remembrance intersected with aspects of the Argentine political process of the last twenty years. Conclusions: The analysis of the construction process and the materiality assumed by its architecture demonstrate, first, how the global dimensions of Holocaust remembrance interact with local contexts and, second, the tensions raised between the actors and organizations that promote its memory and the victims of Nazi persecution in Argentina.

“¡Eso no nos representa!” Historia, contexto(s) y representación en el Monumento Nacional a la Memoria de las Víctimas del Holocausto Judío de Buenos Aires, Argentina

Objective/Context: In the field of Holocaust studies, the Latin American experience has occupied a liminal space. Even when the global character assumed by its forms of remembrance is widely accepted, little attention has been paid to the national cases of this region. This paper deals with a specific national case through the construction record of the National Monument to the Victims of the Jewish Holocaust, located in the city of Buenos Aires, Argentina. The present research reveals the legal and administrative process that accompanied its gestation, the recognition of the actors that intervened throughout the period, and, finally, the character and debates that the architecture of the pantheon provoked. This cycle, which lasted a little more than two decades, allows us to qualify the meaning of the global character of Holocaust memory by considering how this experience was redefined in a national context. Methodology: For this research, qualitative techniques are used in the analysis of the legislative and patrimonial records, journalistic sources, interviews with involved actors, and a documentary film called “Monument,” which aims to give an account of the history of its construction and the representational matrix of that memorial. Originality: Although there have been, in recent years, some works that addressed the memory of the Holocaust in Argentina, they focused on various cultural media: literature, film, and testimonial narratives. This paper addresses an object whose materiality is different—monumental—and which was conceived as a public policy of commemorative character. The analysis of the construction of this memorial pantheon allows recognition of how the transnational dimensions of Holocaust remembrance intersected with aspects of the Argentine political process of the last twenty years. Conclusions: The analysis of the construction process and the materiality assumed by its architecture demonstrate, first, how the global dimensions of Holocaust remembrance interact with local contexts and, second, the tensions raised between the actors and organizations that promote its memory and the victims of Nazi persecution in Argentina.