Aromatic Iodination Research Articles

The Effect of Water on the Reaction of Metal Halides with Organic Acids at Higher Temperatures

AbstractEvolution of hydrogen chloirde occurs when an organic acid which tends to undergo intramolecular dehydration at elevated temperatures is heated with dried sodium chloride at 150°. Aliphatic and aromatic monocarboxylic acids are not acted upon under the same conditions. However, when mono‐ or polycarboxylic acids having a pKa<5.3, are heated with solid calcium chloride dihydrate, the above reaction takes place much more rapidly with the evolution of hydrogen chloride. Calcium chloride is also found to induce elctrophilic aromatic iodination without the presence of any oxidizing agent.

Synthesis of organomercury compounds by reaction of organic halogen compounds with mercury

1. The reactions of several aliphatic and aromatic halogen derivatives with mercury, have been intvestigated 2. It has been shown that reaction of halogen derivatives with mercury is activated by ultraviolet radiation and by benzoyl peroxide, a fact that is an argument in favor of a homolytic mechanism for these reactions. 3. It has been found that aromatic iodine derivatives, and also aliphatic and aliphatic-aromatic bromine derivatives, can react with mercury with formation of organomercury compound.