This paper aims to identify typologies of Latin American cities based on socioeconomic urban environment patterns. We used census data from 371 urban agglomerations in 11 countries included in the SALURBAL project to identify socioeconomic typologies of cities in Latin America. Exploratory factor analysis was used to select a set of variables, and finite mixture modelling (FMM) was applied to identify clusters to define the typology of cities. Despite the heterogeneities among the Latin American cities, we also found similarities. By exploring intersections and contrasts among these clusters, it was possible to define five socioeconomic regional typology patterns. The main features of each one are low-education cities in Northeast Brazil; low-unemployment cities in Peru and Panama; high-education cities in Argentina, Chile, Colombia, Costa Rica, Nicaragua and Mexico; high female labor participation, with high primary education in Argentina and low primary education in Brazil; and low female labor participation and low education in Brazil, Colombia, El Salvador, Guatemala, and Mexico. Identifying clusters of cities with similar features underscores understanding of the urban social and economic development dynamics and assists in studying how urban features affect health, the environment, and sustainability.