In recent times, the use of sustainable building materials is gaining momentum as the general public has started understanding the energy exploitation and also ill effects of using pollutant emitting materials. Also, usage of high energy-intensive materials is on the decline as all international agencies have started making a strong call on climate change (carbon release). Therefore, usage of materials with less embodied energy is the need of the hour. Hence this study aims at exploring the possibilities to optimize the embodied energy and operational energy by selecting sustainable building materials, ventilation and lighting aspects in the design of school buildings. Two designs of school buildings have been done, namely conventional and Regenerative. The conventional design has typically used construction materials like RCC, fired clay brick etc., whereas in regenerative design materials of less embodied energy like CSEB blocks, no VOC paints, etc., have been used. Also in regenerative design, effective ventilation strategies and more openness to sky areas have been done in order to make buildings more passive. Embodied energy for all building components like floor, roof, foundations, wall has been calculated separately and cumulated for the entire floor area. Operational energy was also calculated for both conventional and regenerative design using modeling software plugin. As findings, both embodied energy and operational energy was found to be low for regenerative design when compared with conventional design. As a result, a design with low embodied energy and operational energy has been proposed with all supporting data. Future studies can be done on different material configurations for wall, roofs, floors, foundations and Embodied energy as output for each variable of input. For different ventilation and lighting configurations, operational energy can be found.