ABSTRACT. Sulfoxaflor is recommended for use as an insecticide on wheat, barley, rapeseed, sugar beet, apple and cabbage. In the State Enterprise “L.I. Medved’s Research Center for Preventive Toxicology, Food and Chemical Safety, The Ministry of Health of Ukraine” a study was conducted on the toxicological and hygienic assessment of sulfoxaflor and the insecticide Transform, WG based on it; PDD of sulfoxaflor for humans, hygienic standards of the substance and regulations for safe use of the drug are substantiated. Aim. Toxicological and hygienic assessment of sulfoxaflor and its insecticide, assessment of the risk of exposure to agricultural workers and the population. Methods. Expert-analytical, toxicological, physico-chemical, hygienic. Results. According to the parameters of toxicity, sulfoxaflor and the drug Transform, WG belong to pesticides of the 2nd class of danger according to the limiting criterion of harmfulness – the reproductive toxicity of sulfoxaflor. It has a polytropic effect on the body with predominant damage to the liver and reproductive organs. Mutagenic, carcinogenic and teratogenic activity and embryotoxicity of sulfoxaflor are not limiting when assessing its danger. As a result of field studies, it was established that residual amounts of sulfoxaflor were not detected in the grain of the wheat and barley crops, the seeds of the rape crop and its oil, the roots of the sugar beet crop, the apple crop and their juice, cabbage at the limit level of detection methods. The degree of possible professional risk of exposure to flupyradifurone in case of entering the body of agricultural workers by inhalation and dermal routes does not exceed the permissible level. Conclusions. The use of the insecticide Transform, WG based on sulfoxaflor in the agriculture of Ukraine on wheat, barley, rapeseeds, sugar beetroots, apples and cabbage in compliance with hygienic standards and regulations is not dangerous talking about the sulfoxaflor contamination possibility of agricultural crops and environmental objects. Keywords: insecticide, sulfoxaflor, toxicological properties, hygienic standards and regulations, hazard assessment.
Read full abstract