BACKGROUND: The management of wounds is fundamental in the practice of surgery. The prevalence of leg ulceration is approximately 1% to 2%, and is slightly higher in the older adult population. Lower limb ulcers have a multifactorial etiology, more commonly seen in diabetics. Superoxidised solution is a new concept in wound management, it is an electrochemically processed aqueous solution with neutral pH, non toxic, non-irrigating, no rinse dermal wound irrigant. AIMS: Superoxidised solution was used on Lower Limb Ulcers to observe; Wound disinfection, Decrease in wound size, Appearance of Granulation tissue and Duration of Hospital stay. SETTINGS & DESIGN: This prospective study was conducted at Kempegowda Institute of Medical Sciences & Research Center on a study population of 100 patients from September 2011 to September 2012. Sampling Design is purposive sampling. MATERIAL AND METHODS: Study group included 100 patients above 18yrs of age, traumatic ulcers and diabetic ulcers. Informed consent was taken, routine and specific investigations, swab culture and sensitivity taken. Assessments were done on Day 1, 5, 9, 12, 18, 21. CONCLUSION: Superoxidised solution is safe and effective in lower limb ulcers, and we found it to be efficient with significant improvement in appearance of granulation tissue and epithelization and reduction in duration of hospital stay.