You have accessJournal of UrologyKidney Cancer: Surgical Therapy VI1 Apr 2015PD49-07 IMPACT OF AORTIC CALCIFICATION BURDEN ON RENAL FUNCTION RECOVERY IN RCC PATIENTS AFTER RADICAL NEPHRECTOMY Ken Fukushi, Shingo Hatakeyama, Hayato Yamamoto, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, and Chikara Ohyama Ken FukushiKen Fukushi More articles by this author , Shingo HatakeyamaShingo Hatakeyama More articles by this author , Hayato YamamotoHayato Yamamoto More articles by this author , Atsushi ImaiAtsushi Imai More articles by this author , Takahiro YoneyamaTakahiro Yoneyama More articles by this author , Yasuhiro HashimotoYasuhiro Hashimoto More articles by this author , Takuya KoieTakuya Koie More articles by this author , and Chikara OhyamaChikara Ohyama More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.2725AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The aortic calcification index (ACI) is reported to be closely associated with renal dysfunction and cardiovascular events; however, its implication in patients with radical nephrectomy has not been well examined. In this study, we investigated the relationship between ACI and postoperative renal function in patients with radical nephrectomy. METHODS From Jan 1995 to Dec. 2012, we performed 511 consecutive radical nephrectomies in our hospital. Of those, 83 patients who received regular renal function followup for 5 years were enrolled in this retrospective study. ACI was quantitatively measured on abdominal computed tomography (CT). The relationship between ACI, age, estimated glomerular filtration rates (eGFR) were longitudinally evaluated. Independent factors which influenced on eGFR at 5 years after surgery were determined by liner regression analysis. RESULTS The median age, preoperative eGFR, ACI were 62 years, 69 ml/min/1.73m2, and 4.2%, respectively. ACI were significantly correlated with Preoperative eGFR. Higher ACI (>4.2%) was significantly correlated with older age, inferior eGFR recovery rate. Liner regression analyses showed that preoperative eGFR and ACI were the independent factors which influenced on eGFR at 5 years after surgery. CONCLUSIONS Higher ACI at the time of radical nephrectomy was closely correlates with inferior eGFR recovery and postoperative renal function. All n* 83 Age*(Q1-Q3) 62(50-70) Gender(M/F) 53/30 Pre-surgical eGFR*(Q1-Q3)) 69(54-83) ACI(%)*(Q1-Q3) 4.2(1-18) BMI*(Q1-Q3) 24(22-27) Blood pressure*(Q1-Q3) 95(87-102) *median Liner regression model B beta P value 95%CI pre-eGFR 0.37 0.47 0.000 0.22-0.52 B.ACI -0.27 -0.26 0.008 -0.46-0.07 © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e973 Peer Review Report Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ken Fukushi More articles by this author Shingo Hatakeyama More articles by this author Hayato Yamamoto More articles by this author Atsushi Imai More articles by this author Takahiro Yoneyama More articles by this author Yasuhiro Hashimoto More articles by this author Takuya Koie More articles by this author Chikara Ohyama More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...