One of the risk factors that cause cardiovascular disease is hyperlipidemia. Hyperlipidemia is a condition of increased plasma fat levels consisting of increased cholesterol, triglycerides and LDL levels and decreased HDL levels. The existence of side effects on the body from antihyperlipidemic drug treatment makes herbal medicine one of the alternatives chosen as a treatment for hyperlipidemic patients. Antihyperlipidemic activity testing was carried out on various herbal plants that contain antioxidants. There are 6 types of plant extracts with activity test results that have potential as antihyperlipidemic. The literature study used a search method on the internet related to the keyword "Plants that contain flavonoid compounds and have the potential as antihyperlipidemic" on the Google Scholar page. Primary data is obtained with sources of research results that have been published in national and international journals. The result of our literature review shows that plants that have flavonoids have the potential for antihyperlipidemic. More investigation is required to determine what kind of plants, dose and side effects can improve the herb plants as a substitute for anti-hyperlipidemia treatment