Issues of antibiotic-resistant microorganisms have become a genuine wonder and needs to discover arrangements viable with the peril it addresses. Therefore, scientists have arisen calling to go towards regular other options and sources given commonly by nature. The study focused on the synergistic effectiveness of the cold (E1) and hot (E2) aqueous extracts of the leaves of two plants, Camellia sinensis, and Moringa oleifera, compared with (E3) which is control treatment, subsequent to researching some dynamic and active mixtures in the two plants separates utilizing phytochemical investigation and infrared spectroscopy analysis (FTIR). In addition, their utilization as anti-infection agents to delay the growth of some positive and negative isolated pathogenic bacteria that cause food contamination, by measuring the inhibition zone for bacteria growth, and determine the MIC assay for concentrates. The outcomes showed that the main mixtures combinations that were subjectively analyzed by FTIR were phenols, polyphenols, alkaloids, flavonoids, and other significant mixtures. Results showed that there were significant differences among the bacterial species towards each concentrate, just as clear critical differences among the pre-arranged concentrates towards every one of the confined bacterial species.