Physical inactivity is linked to pregnancy-related complications. Exercise participation during pregnancy is restricted in low-middle income nations, including Ethiopia. Therefore, this study aimed to assess factors associated with physical activity practice among pregnant women attending antenatal care at public health institutions in Debre Berhan Town Northeastern Ethiopia. Institutional based cross-sectional study was conducted from March 22, 2021 to May 22, 2021 in Debre Berhan Town. The systematic random sampling technique was used to obtain the 418 participants. Data were collected by using standardized questionnaires. Data were entered, cleaned by Epi data version 3.1 and analyzed by SPSS version 25. The variables which had p-value < .05 and with 95% confidence interval were declared as determine factors of antenatal physical exercise. According to this study, 222 (53.1%, CI [48.3, 57.7]), 220 (52.6% [47.8, 57.2]), and 218 (52.2% [CI 47.6, 56.7]) of respondents had good knowledge, favorable attitude, and good practice of physical exercise respectively. Age group of 30 to 34 years (AOR: 2.15, 95% CI [1.08, 4.29]), housewife (AOR: 7.81, 95% CI [1.48, 41.21]), cultural recommendation (AOR: 2.16, 95% CI [1.37, 3.39]), exercise before pregnancy (AOR: 2.69, 95% CI [1.72, 4.19]), and gestational age >24 weeks (AOR: 2.538, 95% CI [1.02, 6.29]) were factors associated with practice of physical exercise during pregnancy. Physical activity during pregnancy was more common in the current study than in the national average. During an ANC visit, health care providers should improve and strengthen physical activity counseling sessions.
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