Analysis Of Foot Research Articles

A Bibliometric Analysis of 4 Major Foot and Ankle Surgery Journals

Research publication is a central to the scientific process and comprehensive bibliometric analysis is a leading way to better understand trends within research. Currently, there are limited bibliometric analyses of literature pertaining to foot and ankle surgery. This study aims to quantify the volume of research and investigate what may affect publication and citation. Journals associated with the 3 major orthopedic foot and ankle societies (Foot & Ankle International[FAI], Foot and Ankle Surgery, and The Foot) and one podiatric college (Journal of Foot and Ankle Surgery®) were evaluated from January 2009 to December 2018 using Scopus (Elsevier, Amsterdam, the Netherlands). Descriptive statistics were used to summarize article characteristics and regression modeling was used to determine factors associated with a country's current and future productivity and an article's citation rate. A total of 4994 articles were published over the 10-year period, with the largest contributor of publications being the United States of America (USA), who produced 2096 (41.8%) publications. Regression analysis found no association between a country's productivity and gross domestic product or population. There was no significant relationship between a country's baseline publication rate and future publication rate. The variables significantly associated with an increased citation count were; the number of years since publication, the number of authors, publication in FAI and if the article was a review. To our knowledge this is the largest bibliometric analysis of foot and ankle publications. The majority of research is being produced by the USA, but there are numerous complex factors associated with citation and publication rates. Further research is required to fully assess these factors and characterize the state of foot and ankle surgery research.

Molecular characterization and phylogenetic analysis of foot and mouth disease virus isolates in Sulaimani province, Iraq.

Foot-and-mouth disease (FMD) is endemic in Iraq. The current study can be considered as the first molecular characterization of serotype O in Iraq. The present investigation reported the determination of FMDV serotype O from local farms in Sulaimani districts in 2016 outbreaks. Samples were collected from suspected cattle. The virus was primarily detected with RT-PCR directly from mouth epithelial samples. The direct sequencing and subsequent analysis of amplified PCR products for the VP1 gene indicated the circulation of serotype O of FMD in studied areas. Moreover, phylogenetic analysis revealed that the field isolated serotype O belonged to topotype ME-SA and lineage PanAsia II and clustered with Pakistan and Iran isolates (KU365843 and KY091283) with identity (96.00%, 95.00%) respectively. Furthermore, according to the phylogenic tree, the field isolates had different lineage with the three O/Manisa vaccine strains and Iraq/2000 strains. These findings highlighted the continuous circulation of serotype O of FMD in the region.

Morphometric Analysis of Foot Among Young Adult Population

Morphometric Analysis of Foot Among Young Adult Population

The Application of Forensic Podiatry to Clinical Practice.

The practice of the clinical podiatrist traditionally focuses on the diagnosis and treatment of conditions of the foot, ankle, and related structures of the leg. Clinical podiatrists are expected to be mindful of "the principles and applications of scientific enquiry." This includes the evaluation of treatment efficacy and the research process. In contrast, the forensic podiatrist specializes in the analysis of foot-, ankle-, and gait-related evidence in the context of the criminal justice system. Although forensic podiatry is a separate, specialized field, many aspects of this discipline can be useful in the clinical treatment and management of foot and ankle problems. The authors, who are forensic podiatrists, contend that the clinical podiatrist can gain significant insights from the field of forensic podiatry. This article aims to provide clinical podiatrists with an overview of the principles and methods that have been tested and applied by forensic podiatrists in their practice, and suggests that the clinical practice of the nonforensic foot practitioner may benefit from such knowledge.

Analysis of foot and footprint measurements to determine the sex of an individual

Analysis of foot and footprint measurements to determine the sex of an individual

Neural Computing Improvement Using Four Metaheuristic Optimizers in Bearing Capacity Analysis of Footings Settled on Two-Layer Soils

This study outlines the applicability of four metaheuristic algorithms, namely, whale optimization algorithm (WOA), league champion optimization (LCA), moth–flame optimization (MFO), and ant colony optimization (ACO), for performance improvement of an artificial neural network (ANN) in analyzing the bearing capacity of footings settled on two-layered soils. To this end, the models estimate the stability/failure of the system by taking into consideration soil key factors. The complexity of each network is optimized through a sensitivity analysis process. The performance of the ensembles is compared with a typical ANN to evaluate the efficiency of the applied optimizers. It was shown that the incorporation of the WOA, LCA, MFO, and ACO algorithms resulted in 14.49%, 13.41%, 18.30%, and 35.75% reductions in the prediction error of the ANN, respectively. Moreover, a ranking system is developed to compare the efficiency of the used models. The results revealed that the ACO–ANN performs most accurately, followed by the MFO–ANN, WOA–ANN, and LCA–ANN. Lastly, the outcomes demonstrated that the ACO–ANN can be a promising alternative to traditional methods used for analyzing the bearing capacity of two-layered soils.

Genetic Analysis of Feet and Leg Conformation and Proportion of Crushed Piglets in Austrian Large White and Landrace Sows

Selection for feet and leg traits can increase longevity as well as several performance traits in sows. Moreover, good feet and leg quality contributes improving animal welfare not only for sows, but also for piglets. Sows with feet and leg problems have a higher risk of crushing their piglets when lying down. Therefore, a feet and leg scoring scheme was derived and applied by trained assessors. Furthermore, piglet mortality rate by crushing was recorded. Genetic parameters as well as breeding values were estimated and the effect of the traits on piglet mortality rate by crushing was investigated. Data of 993 Large White and 299 Landrace sows of 23 nucleus farms were analyzed. Heritabilities ranged from 0.03 to 0.16 for piglet mortality rate by crushing and pastern fore legs. Some genetic correlations between feet and leg traits were significantly highly correlated (0.69 to 0.79). Sows with favorable scores for almost all feet and leg scores had higher estimated breeding values for piglet mortality rate. Higher values indicate less crushed piglets and are thus favorable. An introduction of a feet and leg scoring scheme into routine genetic evaluation may thus contribute to animal welfare improvement for sows and piglets.

Analysis of foot and claw diseases/disorders in Czech Holstein cows

Received: 2018-05-07 | Accepted: 2018-05-14 | Available online: 2018-11-26 https://doi.org/10.15414/afz.2018.21.04.194-196 Foot and claw diseases/disorders from 24 545 lactations of 10 340 Holstein cows were recorded on 7 farms in the Czech Republic from 1999 to 2018. There were defined a three groups of foot and claw disorders/diseases: diseases of skin (SD), which cover digital, interdigital dermatitis and interdigital phlegmon; then disorders of the claw horn (CH) including ulcers, white line disease, horn fissures, together with double sole and overall claw diseases (OCD) ingluding all the recorded disorders. The OCD ratio observed during 1 th and 305 th days of lactation was 52.56% of all evaluated lactations. The observed ratio of SD and CH were 28.61% and 27.15%, respectively. A foot and claw disorders were defined as 0/1 occurrence per lactation, for the purposes of analyses,. Genetic parameters were estimated using by linear animal models for evaluated traits. Models included the random additive genetic effect of animal (A), the permanent environmental effect of cow (PE), fixed effects of parity, farm, year and season of calving, and age at calving as discreet variables in classes. The estimated heritability were 13.84%, 12.64% and 9.83%, 8.73% and 9.97%, for OCD, CH, SD, ulcers (U) and for dermatitis digitalis and interdigitalis (DD), respectively. Genetic correlation was 17.66% between SD and CH, whereas traits SD and DD equal high genetic similarity (98.4%). Also correlation between CH and U traits was high (92.62%). The presented results indicate to possibility of selection against foot and claw disorders/diseases for Czech Holstein population. The work was supported by the project QJ1510144 and the institutional support MZE-RO0718 of the Ministry of Agriculture of the Czech Republic. Keywords : cattle, foot and claw disorders, genetic parameters, health traits, udde References Buch, L. H., A. C. Sorensen, J. Lassen, P. Berg, J. A. Eriksson, J. H. Jakobsen, M. K. Sorensen (2011) Hygiene-related and feed-related hoof diseases show different patterns of genetic correlations to clinical mastitis and female fertility. J. Dairy Sci., 94, 1540-1551. Chapinal, N., A. Koeck, A. Sewalem, D. F. Kelton, S. Mason, G. Cramer,F. Miglior (2013) Genetic parameters for hoof lesions and their relationship with feet and leg traits in Canadian Holstein cows. J. Dairy Sci., 96, 2596-2604. Egger-Danner, C., O.K. Hansen, K. Stock, J.E. Pryce, J. Cole, N. Gengler, B. Heringstad (2013) Challenges and benefits of health data recording in the context of food chain quality, management and breeding. ICAR Technical Series. Groeneveld, E., M. Kovac, and N. Mielenz (2008) VCE User’s Guide and Reference Manual, Version 6.0. Krpalkova, L., M. Stipkova & M. Krejcova, 2016. Vliv zdravi paznehtů a urovně reprodukce na výkonnost a zisk stada dojnic. Nas chov, 76 (9), 58-63. Krupova, Z., Krupa, E., Michalickova, M., Wolfova, M., Kasarda, R. (2016) Economic values for health and feed efficiency traits of dual-purpose cattle in marginal areas. Journal of Dairy Science, ,. 99, s. 644-656. Madsen, P. , J. Jensen. 2010. DMU – a package for analysing multivariate mixed models. Version 6, release 5.0., Aarhus University, Foulum, Denmark. Perez-Cabal, M. A. ,N. Charfeddine, N. (2015) Models for genetic evaluations of claw health traits in Spanish dairy cattle. J. Dairy Sci., 98 (11), 8186-8194. Sogstad, A. M., T. Fjeldaas, O. Osteras, K. P. Forshell. (2005) Prevalence of claw lesions in Norwegian dairy cattle housed in tie stalls and free stalls. Prev. Vet. Med., 70, 191-209. van der Spek, D., J.A. van Arendonk, A.A. Vallee, H. Bovenhuis (2013) Genetic parameters for claw disorders and the effect of preselecting cows for trimming. J Dairy Sci., 96 (9), 6070-6078. van der Waaij, E. H., M. Holzhauer, E. Ellen, C. Kamphuis, G.de Jong. (2005) Genetic parameters for claw disorders in Dutch dairy cattle and correlations with conformation traits. J. Dairy Sci., 88, 3672-3678.

Molecular epidemiology and phylogenetic analysis of foot and mouth disease virus type ‘O’ and evaluation of its carrier state in cattle of Assam by Real time PCR

The molecular epidemiological study of foot-and-mouth disease virus (FMDV) has been carried out from different outbreaks in Assam the present study is based on the nucleotide sequencingof circulating FMDV serotype. The samples were subjected to sandwich ELISA, multiplex-PCR and molecular phylogeny to identify the type species. The phylogenetic analysis of virus sequence revealed similarity with theBangladesh isolates in the major branching pattern. The serotype ‘O’has found to be dominant and responsible for most of the recentoutbreaks.Thepersistence of serotype ‘O’ and cytokines expression of IL-1á, IL-1â, IFN-á, TNF-á in blood of recovered animals were done by Real time PCR. The findings indicated that IL-1á, IFN-á and TNF-á genes were up-regulated upto 3 months post infection but IL-1â found to be down regulated with progression of recovery. The present study thus supports that real-time PCR is a powerful technique for reliable detection of persistent FMDV in recovered animals.

Static Force Analysis of Foot of Electrically Driven Heavy-Duty Six-Legged Robot under Tripod Gait

The electrically driven six-legged robot with high carrying capacity is an indispensable equipment for planetary exploration, but it hinders its practicability because of its low efficiency of carrying energy. Meanwhile, its load capacity also affects its application range. To reduce the power consumption, increase the load to mass ratio, and improve the stability of robot, the relationship between the walking modes and the forces of feet under the tripod gait are researched for an electrically driven heavy-duty six-legged robot. Based on the configuration characteristics of electrically driven heavy-duty six-legged, the typical walking modes of robot are analyzed. The mathematical models of the normal forces of feet are respectively established under the tripod gait of typical walking modes. According to the MATLAB software, the variable tendency charts are respectively gained for the normal forces of feet. The walking experiments under the typical tripod gaits are implemented for the prototype of electrically driven heavy-duty six-legged robot. The variable tendencies of maximum normal forces of feet are acquired. The comparison results show that the theoretical and experimental data are in the same trend. The walking modes which are most available to realize the average force of distribution of each foot are confirmed. The proposed method of analyzing the relationship between the walking modes and the forces of feet can quickly determine the optimal walking mode and gait parameters under the average distribution of foot force, which is propitious to develop the excellent heavy-duty multi-legged robots with the lower power consumption, larger load to mass ratio, and higher stability.

An Analysis of Foot and Ankle Device Recalls by the Food and Drug Administration.

IntroductionOrthopaedic devices represent 12% of all medical device recalls. Products are approved through pre-market approval (PMA) or the 510(k) premarket notification process. No previous evaluation was found in the literature evaluating foot and ankle device recalls. The field of foot and ankle subspecialty has seen a rapid growth in innovation related to implants in recent years.MethodsThe Food and Drug Administration (FDA) Device Recall database was evaluated for all foot and ankle devices from 2007 through 2017 for the manufacturer, process of approval, type of implant, recall class, dates of initiation and termination of the recall, manufacturer determined reason, quantity affected, and distribution within the United States or internationally.ResultsA total of 161 products from 33 companies were identified with 158 (98.1%) approved through the 510(k) process. The most common reason for device recall was due to the device breaking intraoperatively or postoperatively. The average length of the recall was 487.5 days. ConclusionsDevice recall is not an uncommon event with the majority of products approved through the less demanding 510(k) process.

Genome-wide association study and functional analysis of feet and leg conformation traits in Nellore cattle.

Feet and leg conformation is evaluated as a subset of conformational structure traits in dairy and beef cattle and is related to the feet and leg quality that can compromise the animals' productive performance and longevity. The aim of this study was to perform a genome-wide association study (GWAS) of two traits related to feet and leg conformation in Nellore cattle to identify chromosomal regions related to the expression of these traits. Phenotypic and pedigree data from 104,725 animals and genotypes from 1,435 animals and 407,730 SNPs were used. Feet and leg structure was evaluated as a binary trait (FL1) to identify yearling animals with feet and leg problems or as categorical score (FL2) to assess the overall quality of their feet and leg. The top ten 1-Mb windows that explained the largest proportion of the total genetic variance were identified and functional enrichment analyses were performed. The 10 windows with large effects obtained for FL1 are located on chromosomes 1, 2, 6, 7, 8, 10, and 14, and together explained 8.96% of the additive genetic variance. For FL2, these windows are located on chromosomes 1, 7, 10, 11, 18, 20, 22, 28, and 29, explaining 8.98% of the additive genetic variance. Several candidate genes were identified, including DLX2 which is associated with osteogenic differentiation, IL-1β and IL-1A associated with some properties of articular cartilage, PiT1 which plays an important role in bone physiology, and CTSL associated with rheumatoid arthritis. The results presented here should contribute to a better understanding of the genetic and physiologic mechanisms regulating both traits, and identifies candidate genes for future investigation of causal mutations.

Joint assessment of handedness and footedness through latent class factor analysis

ABSTRACTRecently, some studies have demonstrated the effectiveness of two latent variable approaches in which hand preferences are analysed using either latent class methods or latent class factor (LCF) methods. The main aims of this study are: (i) to establish whether these approaches are adequate for assessing footedness, (ii) to evaluate their appropriateness when hand and foot preferences are jointly analysed, and (iii) to measure the association between handedness and footedness based on the examined latent variable models. To this end, a dataset providing information about the limb used to perform ten hand actions and three foot movements by 2236 young Italian sportspeople is analysed. The first aim is pursued through an exploratory analysis of the observed foot preferences; according to this analysis, footedness patterns are adequately described by two latent levels of footedness. As far as the second aim is concerned, a confirmatory analysis of foot and hand preferences is carried out; the best fit to the dataset is obtained using a two-dimensional LCF model with four latent levels of handedness and two latent levels of footedness. Finally, the association between handedness and footedness resulting from the employed methods is remarkably lower than that registered in other studies.

Analysis of foot and mouth disease in dairy animals: an assessment of cost and loss from sample farmers

Response from 60-farm owners was analyzed to assess the economic impacts of foot and mouth disease. Data were recorded through personal interview methods during 2006-07 from small farmers across the villages of Pune region. The loss in terms of reduced revenues and cost as extra resources used for treatment were quantified and aggregated. The estimated production loss to the tune of Rs. 3184.00 in crossbreeds cows and Rs. 3062.50 in buffaloes, whose share was 74.31 and 81.69 per cent, respectively. The major loss component was reduction in milk yield, accounted Rs. 894.60 and Rs.510.00, represents 20.88 and 13.60 per cent of the total loss in crossbred cows and buffaloes, respectively. The cost of treatment was worked out to be Rs. 1313.80 in crossbred cows and Rs. 645.63 in buffaloes. The cost of medicine alone had constituted around 50 percent of total cost component, reflecting a tune of Rs. 675.60 in crossbred and Rs. 281.25 in buffaloes. The expenses were worked out to be Rs. 5598.80 in crossbred and Rs. 4394.38 in buffaloes per animal, which shows the expenses due to the disease, was comparatively higher in the crossbred cows. Movement of animals was ascertained to be the reason for spread of this disease in 80 per cent farm perception.

Mutational analysis of foot and mouth disease virus nonstructural polyprotein 3AB-coding region to design a negative marker virus

Inactivated purified whole virus vaccines are used for control of foot and mouth disease (FMD). ELISAs detecting antibodies to the nonstructural proteins (NSP), a marker of infection, are primarily used to differentiate FMD virus (FMDV) infected from vaccinated animals (DIVA). However, such DIVA assays have a limitation to their specificity since residual NSPs present in the relatively impure vaccines are suspected to induce an NSP-antibody response in the repeatedly vaccinated animals. Epitope-deleted negative marker vaccine strategy seems to have an advantage over the conventional vaccines in identifying the infected animals with accuracy. NSP 3AB contains an abundance of immunodominant B-cell epitopes of diagnostic importance. This study addresses the feasibility of producing 3AB-truncated FMDV mutant as a potential negative marker vaccine candidate. An infectious cDNA clone of FMDV serotype Asia 1 strain was used to engineer an array of deletion mutations in the established antigenic domain of 3AB. The maximum length of deletion tolerated by the virus was found to be restricted to amino acid residues 87–144 in the C-terminal half of 3A protein along with deletion of the first two copies of 3B peptide. The 3AB-truncated marker virus (Asia 1 IND 491/1997Δ3A87-1443B1,2+FLAG) demonstrated infectivity titres comparable to that of the parental virus in BHK-21 (log10 7.42 TCID50/ml) and LFBK-αVβ6 (log10 8.30 TCID50/ml) cell monolayer culture. The protein fragment corresponding to the viable deletion in the 3AB region was expressed in a prokaryotic system to standardize a companion assay (3A87-1533B1,2 I-ELISA) for the negative marker virus which showed reasonably high diagnostic sensitivity (96.9%) and specificity (100% for naïve and 97.1% for uninfected vaccinated samples). The marker virus and its companion ELISA designed in this study provide a basis to devise a marker vaccine strategy for FMD control.

Hoof Quality of Anglo-Arabian and Haflinger Horses.

IntroductionFoot quality is essential to the horse’s movement. The barefoot approach favours the animal’s welfare. Environment and selection determine hoof characteristics.Material and MethodsHoof characteristics of eight Anglo-Arabian (AA) and nine Haflinger (HA) horses were studied. After a preliminary visual analysis of feet, nail samples were collected after trimming for physico-chemical analysis. The parameters were submitted to analysis of variance. A principal component analysis and a Pearson correlation were used to compare mineral contents.ResultsThe hooves of both breeds were healthy and solid. The hooves of HA horses were longer than those of AA horses (14.90 ±0.30 cm vs 13.10 ±0.60 cm), while the AA hoof was harder than the HA hoof both in the wall (74.55 ±2.95 H vs 60.18 ±2.67 H) and sole (67.00 ±5.87 H vs 43.0 ±4.76 H). In comparison with the sole, the AA hoof wall also had a lower moisture percentage (12.56 ±0.67% vs 20.64 ±0.76%), while crude protein and ash contents were similar in both regions. The AA hoof showed a higher Se content, while the HA hoof had a higher level of macroelements. The negative correlations of K with Cu, Fe, Ni, Pb, and Zn in the AA hoof may indicate osmoregulation activity.ConclusionThe hoof morphology of AA and HA horses met the literature parameters for mesomorphic horses. Both breeds had healthy and well-conformed hooves, useful for sport and recreation activities.

Comparison of Multisegmental Foot and Ankle Motion Between Total Ankle Replacement and Ankle Arthrodesis in Adults.

Total ankle replacement (TAR) and ankle arthrodesis (AA) are usually performed for severe ankle arthritis. We compared postoperative foot segmental motion during gait in patients treated with TAR and AA. Gait analysis was performed in 17 and 7 patients undergoing TAR and AA, respectively. Subjects were evaluated using a 3-dimensional multisegmental foot model with 15 markers. Temporal gait parameters were calculated. The maximum and minimum values and the differences in hallux, forefoot, hindfoot, and arch in 3 planes (sagittal, coronal, transverse) were compared between the 2 groups. One hundred healthy adults were evaluated as a control. Gait speed was faster in the TAR ( P = .028). On analysis of foot and ankle segmental motion, the range of hindfoot sagittal motion was significantly greater in the TAR (15.1 vs 10.2 degrees in AA; P = .004). The main component of motion increase was hindfoot dorsiflexion (12.3 and 8.6 degrees). The range of forefoot sagittal motion was greater in the TAR (9.3 vs 5.8 degrees in AA; P = .004). Maximum ankle power in the TAR (1.16) was significantly higher than 0.32 in AA; P = .008). However, the range of hindfoot and forefoot sagittal motion was decreased in both TAR and AA compared with the control group ( P = .000). Although biomechanical results of TAR and AA were not similar to those in the normal controls, joint motions in the TAR more closely matched normal values. Treatment decision making should involve considerations of the effect of surgery on the adjacent joints. Level III, case-control study.

Genetic analysis of feet and leg conformation traits in Nelore cattle1

Feet and leg conformation scores are important traits in beef cattle because they encompass a wide range of locomotion disorders that can lead to productive and reproductive losses. Thus, the study of feet and legs in beef cattle is essential for evaluating possible responses to selection focusing on minimizing economic losses caused by the occurrence of feet and leg problems. The aim of this study was to estimate variance components for feet and leg conformation traits in Nelore cattle. The data set contained records of approximately 300,000 animals that were born between 2000 and 2013. These animals belonged to the commercial beef cattle breeding program of the CRV Lagoa (). Feet and legs were evaluated by assigning visual scores at 2 different time points: feet and leg evaluated as a binary trait (FL1), measured at yearling (about 550 d of age) to identify whether (or not) an animal has feet and leg defects, and feet and leg score (FL2), ranging from 1 (less desirable) to 5 (more desirable) was assigned to the top 20% of animals according to the selection index adopted by the beef cattle breeding program, which was measured 2 to 5 mo after the yearling evaluation. The FL1 and FL2 traits were analyzed together with yearling weight (YW). The (co)variance components and breeding values were estimated by Bayesian inference using 2-trait animal models. The posterior means (standard errors) of the heritabilities for FL1, FL2, and YW were 0.18 (0.04), 0.39 (0.07), and 0.47 (0.01), respectively. The results indicate that the incidence of feet and leg problems in this population might be reduced by selection. The genetic correlation between FL1 and FL2 (-0.47) was moderate and negative as expected because the classification score that holds up each trait has opposite numerical values. The genetic trends estimated for FL1 and FL2 (-0.042 and 0.021 genetic standard deviations per year, respectively) were favorable and they indicate that the independent culling strategy for feet and leg problems promotes favorable changes and contributes to the genetic progress of these traits in the population under study.

Reliability bearing capacity analysis of footings on cohesive soil slopes using RFEM

Reliability analysis of bearing capacity of a strip footing at the crest of a simple slope with cohesive soil was carried out using the random finite element method (RFEM). Analyses showed that the coefficient of variation and the spatial correlation length of soil cohesion can have a large influence on footing bearing capacity, particularly for slopes with large height to footing width ratios. The paper demonstrates cases where a footing satisfies a deterministic design factor of safety of 3 but the probability of design failure is unacceptably high. Isotropic and anisotropic spatial variability of the soil strength was also considered.

Ultrasound-guided therapeutic injections for neural pathology about the foot and ankle: a 4year retrospective review.

To describe a 4-year clinical experience with ultrasound-guided therapeutic perineural injections of peripheral nerves about the foot and ankle. Retrospective analysis of foot and ankle perineural injections performed between January 2012 and August 2016. Demographics, clinical indications, presence of structural pathology, immediate and interval pain relief, as well as complications were recorded. Fifty-nine therapeutic injections were performed among 46 patients, accounting for multiple injections in a single visit or multiple visits [mean age = 43years (range 18-75), 31 female (67%) and 15 male (33%)]. Most commonly, perineural injections involved the hallux branch of the medial plantar nerve (n = 17, 22%). Least commonly, perineural injections involved the saphenous nerve (n = 3, 4%). Other injections in our series include sural (10), superficial (11) and deep (7) peroneal, medial (5) and lateral (3) plantar nerves, and the posterior tibial nerve (3). Ultrasound evaluation revealed structural abnormality associated with the nerve in 30 cases (51%)-most commonly thickening with perineural scarring (n = 14). Of 45 injections with complete documentation, immediate relief of symptoms was reported in 43 (96%) cases. Interval symptom relief was achieved in 23 injections [short term (n = 12), intermediate (n = 6), and long term (n = 5)] out of 38 for which follow-up was available (61%). Complications are rare, occurring in only one case. Ultrasound-guided perineural injections about the foot and ankle are safe and provide lasting symptomatic relief for many indications. Concomitant sonographic evaluation identifies structural abnormalities that may contribute to neuropathic symptoms, allowing targeting of injection or clinical therapy.