Amount Of Use Research Articles

Aroma profiles of shalgam: Effect of purple carrot (Daucuscarota) amount.

Shalgam is a fermented product characterized by its color and aroma compounds. However, there is no standard regarding the amount of use of purple carrot, which is the major raw material in production and affects the fermentation and aroma compounds of the product. This present research was designed to examine the effect of purple carrot concentrations on aroma compounds, which are one of the most important characteristics that reflect the quality characteristics of shalgam and affect consumer preferences. Aroma compounds in shalgam juices produced using five different amounts of carrots were analyzed by gas chromatography-flame ionization detector-mass spectrometry (GC-FID-MS). As expected, since the difference between the produced shalgam beverages was only the amount of purple carrots, a qualitative similarity and a quantitative difference were determined in the aroma profiles in general. In the aroma categories defined, terpenes (26 compounds) were the most abundant compounds, followed by esters (17 compounds) and higher alcohols (11 compounds). 88 aroma compounds have been identified in shalgam, and a total of 28 ACs, including 7 terpenes, 7 esters, 3 alcohols, 4 volatile acids, 3 volatile phenols, 1 lactone, 1 norisoprenoid, and 2 naphthalenes, were detected for the first time. The concentration of aromas in the samples varied from 5471.5 to 6490.1 μg/L (p < .05). According to principal component analysis, it was determined that the correlation between the position of the shalgam samples in the coordinate system and the aroma groups was significant. This study shows that purple carrots also affect the aroma compounds of shalgam beverages.

Synergistic interaction of co-exposure to humidifier disinfectant chemicals CMIT/MIT and PHMG in lung injury.

A number of biocidal disinfectant chemicals are used as household products to prevent spread of pathogens. People are commonly exposed to multiple chemicals through those disinfectants. However, effects of interactions (e.g., synergism) between disinfectants on human health outcomes have been rarely studied. In this study, we aimed to investigate associations of a mixture of chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) and polyhexamethylene guanidine (PHMG), which had been used as humidifier disinfectants (HDs) in South Korea, with HD-associated lung injury (HDLI) in a Korean population (n = 4058) with HD exposure through use of HD products. Exposure to HD was retrospectively assessed by an interview-based standardized survey, and HDLI was determined by clinical assessment. After adjusting for covariates, PHMG-specific exposure indices (e.g., amount of use, indoor air concentration, and weekly exposure level) were dose-dependently associated with HDLI (their odds ratios for the comparison of third tertile versus first tertile were 1.95, 1.77, and 2.16, respectively). CMIT/MIT exposure was not observed to have a significant association with HDLI in a single chemical exposure model; however, associations between PHMG exposure and HDLI were strengthened by co-exposure to CMIT/MIT in combined chemical exposure models, where synergistic interactions between CMIT/MIT use and PHMG indices (amount of use and weekly exposure level) were observed (p-interaction in additive scale: 0.02 and 0.03, respectively). Our findings imply that adverse effects of PHMG exposure on lung injury among HD users might be worsened by co-exposure to CMIT/MIT. Given that plenty of household products contain disinfectants on global markets, epidemiological and toxicological investigations are warranted on interaction effects of co-exposure to disinfectants.

Labor productivity in retail trade

In the conditions of the war and the post-war Urainian economic recovery, human capital is one of the determining factors of the state’s existence and ensuring its competitiveness. The loss of human capital has caused a shortage of labor resources in various sectors of the economy, which affects the possibilities of gene­rating income and, as a result, financial results of economic entities. One of the largest components of the Ukrainian economy, which fills the budgets of all levels and creates jobs, is retail trade, which accounts for a significant share of employees among all types of economic activity. The dependence of the revenue amount from the sale of products (goods, services) on the amount of use of economic resources, including labor resources, is widely known. In view of the need for post-war reconstruction against the background of a shortage of labor resources, the aim was set to verify the truth of the principles of the relationship between the scope of activities and the amount of resources used, formulated back in the days of neoclassical economics. Verification of the truth of the formulated hypotheses was carried out on the basis of the use of correlation methods and regression analysis. According to the calculation results, it was not possible to fully illustrate the direct proportional dependence of revenue on the average number of employees for the formed sample of retail trade enterprises. There is also a lack of direct relationship between revenue and labor productivity for both larger and smaller retail enterprises. Further research will be aimed at substantiating other samples of Ukrainian retail trade enterprises and finding interdependencies between their scope of acti­vity and the amount of economic resources involved in the conditions of war and post-war recovery.

An examination of cannabis use motives among couples with intimate partner violence and alcohol use disorder.

Cannabis use is highly prevalent among individuals with a history of intimate partner violence (IPV) and among people who drink alcohol. Motives for cannabis use are important correlates of consumption and problem severity. However, no research has examined cannabis use motives among couples with IPV. The goals of the study were to examine (1) the associations between a person and their partner's cannabis use motives; and (2) examine the extent to which each partners'cannabis use motives are related to their own and their partner's cannabis consumption. Participants were 100 couples (n = 92 different-sex couples, n = 8 same-sex couples) who reported physical IPV in their current relationship. Certain cannabis motives (coping and conformity) and behaviors (cannabis use frequency, quantity and drug-related problems) were positively associated between intimate partners. One's own higher coping motives were associated with greater frequency of cannabis consumption; higher conformity motives were associated with less quantity of consumption; higher social motives were associated with greater quantity of cannabis consumption; and one's partner's social motives were associated with less quantity of cannabis consumption. DISCUSSIONAND CONCLUSIONS: Findings suggest that couples report similar motives for cannabis use, and that one's own and their partner's motives may differentially influence frequency and quantity of use. This study provides novel information on congruency between cannabis use motives and behaviors between intimate partners, as well as how both an individual and their partner's motives for use can influence an individual's cannabis use behaviors.

Observed Instagram use and satisfaction with life: Associations with received communications and exploration of others' content after posting a selfie.

Over 70% of Americans use social media platforms, like Instagram. With this high prevalence, researchers have investigated the relationship between social media use and psychological well-being. Extant research has yielded mixed results, however, as most measures of social media use are self-reported and focus on amount of use. Even when studies account for type of social media use, such as active or passive use, there remains much to be captured. To address this, we asked participants to report their satisfaction with life and then recorded their actual Instagram activity for 10 minutes after posting a "selfie" portrait to their account. We coded the observed Instagram activity into the following four clusters of experiences: communications received, communications sent, monitoring self-related content, and exploring other-related content. We found that greater life satisfaction was associated with higher frequency of receiving communications and viewing other-related content. Life satisfaction was not associated with frequency of sending communications and self-monitoring. Surprisingly, none of the clusters of Instagram experiences were negatively associated with life satisfaction. Our findings highlight the importance of objective data and moving beyond the active/passive dichotomy of social media use to consider additional experiences.

Visual memory and alcohol use in a middle-aged birth cohort

Light and moderate alcohol use has been reported to be associated with both impaired and enhanced cognition. The purpose of this study was to explore whether there was a linear relationship between visual memory and alcohol consumption in males and females in a large middle-aged birth cohort population in cross-sectional and longitudinal settings. Data were collected from 5585 participants completing 31-year (1997–1998) and 46-year (2012–2014) follow-ups including Paired Associate Learning (PAL) test at 46-years follow-up. The participants were originally from 12,231 study population of the Northern Finland Birth Cohort 1966 (NFBC1966). The PAL test was conducted to assess visual memory. Reported alcohol use was measured as total daily use of alcohol, beer, wine, and spirits converted into grams and as frequency and amount of use of beer, wine, and spirits. The total daily alcohol use was not associated with reduced visual memory. The frequency of use of beer and wine in males was associated with better visual memory in cross-sectional and longitudinal settings. Using six or more servings of spirits was associated with worse visual memory in males in cross-sectional and longitudinal settings. The study suggested a lack of a linear association between drinking and visual memory in the middle-aged population.

Post-traumatic stress and future substance use outcomes: leveraging antecedent factors to stratify risk.

Post-traumatic stress disorder (PTSD) and substance use (tobacco, alcohol, and cannabis) are highly comorbid. Many factors affect this relationship, including sociodemographic and psychosocial characteristics, other prior traumas, and physical health. However, few prior studies have investigated this prospectively, examining new substance use and the extent to which a wide range of factors may modify the relationship to PTSD. The Advancing Understanding of RecOvery afteR traumA (AURORA) study is a prospective cohort of adults presenting at emergency departments (N = 2,943). Participants self-reported PTSD symptoms and the frequency and quantity of tobacco, alcohol, and cannabis use at six total timepoints. We assessed the associations of PTSD and future substance use, lagged by one timepoint, using the Poisson generalized estimating equations. We also stratified by incident and prevalent substance use and generated causal forests to identify the most important effect modifiers of this relationship out of 128 potential variables. At baseline, 37.3% (N = 1,099) of participants reported likely PTSD. PTSD was associated with tobacco frequency (incidence rate ratio (IRR): 1.003, 95% CI: 1.00, 1.01, p = 0.02) and quantity (IRR: 1.01, 95% CI: 1.001, 1.01, p = 0.01), and alcohol frequency (IRR: 1.002, 95% CI: 1.00, 1.004, p = 0.03) and quantity (IRR: 1.003, 95% CI: 1.001, 1.01, p = 0.001), but not with cannabis use. There were slight differences in incident compared to prevalent tobacco frequency and quantity of use; prevalent tobacco frequency and quantity were associated with PTSD symptoms, while incident tobacco frequency and quantity were not. Using causal forests, lifetime worst use of cigarettes, overall self-rated physical health, and prior childhood trauma were major moderators of the relationship between PTSD symptoms and the three substances investigated. PTSD symptoms were highly associated with tobacco and alcohol use, while the association with prospective cannabis use is not clear. Findings suggest that understanding the different risk stratification that occurs can aid in tailoring interventions to populations at greatest risk to best mitigate the comorbidity between PTSD symptoms and future substance use outcomes. We demonstrate that this is particularly salient for tobacco use and, to some extent, alcohol use, while cannabis is less likely to be impacted by PTSD symptoms across the strata.

A phase III multisite randomised controlled trial to compare the efficacy of cannabidiol to placebo in the treatment of cannabis use disorder: the CBD-CUD study protocol

BackgroundCannabis use disorder (CUD) is increasingly common and contributes to a range of health and social problems. Cannabidiol (CBD) is a non-intoxicating cannabinoid recognised for its anticonvulsant, anxiolytic and antipsychotic effects with no habit-forming qualities. Results from a Phase IIa randomised clinical trial suggest that treatment with CBD for four weeks reduced non-prescribed cannabis use in people with CUD. This study examines the efficacy, safety and quality of life of longer-term CBD treatment for patients with moderate-to-severe CUD.Methods/DesignA phase III multi-site, randomised, double-blinded, placebo controlled parallel design of a 12-week course of CBD to placebo, with follow-up at 24 weeks after enrolment.Two hundred and fifty adults with moderate-to-severe CUD (target 20% Aboriginal), with no significant medical, psychiatric or other substance use disorders from seven drug and alcohol clinics across NSW and VIC, Australia will be enrolled.Participants will be administered a daily dose of either 4 mL (100 mg/mL) of CBD or a placebo dispensed every 3-weeks. All participants will receive four-sessions of Cognitive Behavioural Therapy (CBT) based counselling. Primary endpoints are self-reported cannabis use days and analysis of cannabis metabolites in urine. Secondary endpoints include severity of CUD, withdrawal severity, cravings, quantity of use, motivation to stop and abstinence, medication safety, quality of life, physical/mental health, cognitive functioning, and patient treatment satisfaction. Qualitative research interviews will be conducted with Aboriginal participants to explore their perspectives on treatment.DiscussionCurrent psychosocial and behavioural treatments for CUD indicate that over 80% of patients relapse within 1–6 months of treatment. Pharmacological treatments are highly effective with other substance use disorders but there are no approved pharmacological treatments for CUD. CBD is a promising candidate for CUD treatment due to its potential efficacy for this indication and excellent safety profile. The anxiolytic, antipsychotic and neuroprotective effects of CBD may have added benefits by reducing many of the mental health and cognitive impairments reported in people with regular cannabis use.Trial registrationAustralian and New Zealand Clinical Trial Registry: ACTRN12623000526673 (Registered 19 May 2023).

EVALUATION OF ANTIBIOTIC USE USING THE ATC/DD AND DU 90% METHODS IN OUTPATIENT PATIENTS IN PUSKESMAS RI TENAYAN RAYA

Infectious diseases are one of the health problem that threaten developing countries, including Indonesia. Riau as one of the provinces with its coastal coverage is not spared from this problem. Inaccurate use of antibiotics is found in the wider community, which can be a cause of negative risks such as antibiotic resistance. Antibiotics are drugs that are used to treat diseases caused by microbes. The improper use of antibiotics can lead to a risk of resistance. Resistance can be avoided using antibiotics. This study aimed to classify antibiotic use using ATC codes and determine the quantity of antibiotic use in outpatients by calculating the DDD. This research method was observational, with a descriptive design and retrospective data collection using secondary data by searching medical records. The sample in this study consisted of outpatients at the Tenayan Raya Inpatient Health Center Outpatient Installation between January and December 2022 who received antibiotic therapy with an ATC code and DDD value in accordance with the provisions of the WHO Collaborating Center, using a total sampling technique.The results of the study showed that based on the ATC/DDD and DU 90% methods, there were 3 antibiotics with the highest quantity of use, namely amoxicillin at 165,92 DDD/1000 KPRJ with a percentage of 67,02%, ciprofloxacin at 41,07 DDD/1000 KPRJ with a percentage of 16,59 %, and cefixime as much as 14,69 DDD/1000 KPRJ with a percentage of 5,93%. Keywords: antibiotics, ATC/DD, DU 90%, resistance

Evolving a Methodology for Assessing Pesticide Pressure on Water Bodies under Data Scarce Conditions: A Case Study on the Marmara Basin in Türkiye

Evolving a Methodology for Assessing Pesticide Pressure on Water Bodies under Data Scarce Conditions: A Case Study on the Marmara Basin in Türkiye

Associations between hair-derived cannabinoid levels, self-reported use, and cannabis-related problems

RationaleAs cannabis potency and cannabis use are increasing in newly legalized markets, it is increasingly important to measure and examine the effects of cannabinoid exposure.ObjectivesThe current study aims to assess how hair-derived cannabinoid concentrations – offering insight into three-month cumulative exposure – are associated with common self-report measures of cannabis use and cannabis use-related problems.Methods74 near-daily dependent cannabis users self-reported their quantity of cannabis use, cannabis use-related problems, and estimated cannabis potency. Hair samples were provided to quantify Δ9-THC, CBD, and CBN using LC–MS/MS and THC-consumption was verified by analyzing THC-COOH in hair using GC–MS/MS.ResultsCannabinoids were detectable in 95.95% of the hair samples from individuals who tested positive on a urine screen for cannabis. Δ9-THC concentrations were positively associated with measures of self-reported potency (relative potency, potency category, and perceived ‘high’), but Δ9-THC, CBD, CBN concentrations and THC/CBD ratio were not associated with self-reported quantity of use. Self-reported potency, but not hair-derived concentrations, were associated with withdrawal and craving. Self-reported quantity of cannabis use, but not cannabinoid concentrations, were associated with cannabis use-related problems.ConclusionsThe use of hair-derived cannabinoid quantification is supported for detecting cannabis use in near-daily users, but the lack of associations between hair-derived cannabinoid concentrations and self-report measures of use does not support the use of hair analyses alone for quantification of cannabinoid exposure. Further research comparing hair-derived cannabinoid concentrations with other biological matrices (e.g. plasma) and self-report is necessary to further evaluate the validity of hair analyses for this purpose.

Combined repetitive facilitative exercise under continuous neuromuscular electrical stimulation and task-oriented training for hemiplegic upper extremity during convalescent phase after stroke: before-and-after feasibility trial.

Whereas repetitive facilitative exercise (RFE) affects primarily recovery of motor impairment after stroke, task-oriented training (TOT) focuses on facilitating daily use of the affected upper extremity. However, feasibility of combined RFE and TOT has not been reported. We originated "task-oriented RFE," as a new combination therapy for patients with hemiplegic upper extremity after subacute stroke, to examine its feasibility in convalescent rehabilitation wards. This is a before-and-after pilot study. Eight patients with hemiplegic upper extremity after subacute stroke received the task-oriented RFE program for 6 weeks at 80 min per day (20-60 min of TOT applied after 60-20 min of RFE under continuous neuromuscular electrical stimulation) in a convalescent rehabilitation ward. In the current program, we introduced the Aid for Decision-making in Occupation Choice (ADOC) iPad application as a goal-setting method for determining tasks. Feasibility was assessed with adherence to the protocol, adverse events in response to the intervention, and preliminary efficacy. Motor functions, amount of use and quality of movement in the hemiparetic upper extremity, and satisfaction of the patients were evaluated with Fugl-Meyer Assessment (FMA), the Action Research Arm Test (ARAT), the motor activity log (MAL) for the amount of use (AOU) and quality of movement (QOM) of the paralyzed hand, and ADOC. All participants accomplished the program, which was implemented as originally planned; neither nonattendance nor an adverse event occurred during the study. Favorable outcomes were obtained with all measures; mean changes in FMA, ARAT in the dominant hand, MAL-AOU, and MAL-QOM were greater than minimal clinically important differences. Mean changes in ADOC were greater than the minimal detectable change. The task-oriented RFE program was safe, well-tolerated, beneficial, and feasible within 80 min a day of occupational therapy, which means also within the procedural constraints of the Japanese health insurance system during the convalescent phase. Future studies are warranted to examine whether combined RFE and TOT enhances the efficacies of each program alone.

Carcinogenicity of asbestos-free talc and talcum powder: A systematic review of the epidemiological evidence after the 2006 monograph of the International Agency for Research on Cancer.

in 2006, the International Agency for Research on Cancer (IARC) concluded that the evidence of carcinogenicity for asbestos-free talc was inadequate (group 3), whereas perineal use of talcum powder was classified as possibly carcinogenic (group 2B). to assess whether later studies provide more solid information on the carcinogenic risk from asbestos-free talc and talcum powder and a better characterization of exposure. systematic review. cohort studies of talc miners and millers exposed to asbestos-free talc, as well as cohort and case-control studies reporting cancer risk in talc powder consumers published from 2006 onwards were identified through PubMed and reference lists. Pooled analyses were included, but not reviews and meta-analyses. In the case of repeatedly reported studies, the article with the longest follow-up or the largest number of observed cases was selected for data abstraction. Notice was taken of studies which were both reported individually and included in pooled analyses. publications meeting inclusion criteria were: 2 cohort studies on talc miners and millers, 10 cohort studies on talcum powder users (4 of which estimated ovarian cancer risk), and 14 case-control studies (13 on ovarian and 1 on endometrial cancer) on the risk from talcum powder use. No excess cancer mortality has been reported among asbestos-free talc miners and millers. Case-control studies consistently led to estimates of ovarian cancer excesses associated with the use of perineal talcum powder (odds ratios up to 1.5). Most studies quantifying exposure also provided evidence of a dose-response relationship. Individual cohort studies estimated hazard ratios (HR) just above 1. In an analysis of pooled cohorts for a total of 3,112 cases, the HR for women with patent reproductive tract was 1.13 (95%CI 1.01-1.26) with a correlation between HR and frequency of use (p for trend 0.03). In all cohort studies, the perineal use of talcum powder was measured only once in the early phases of follow-up, thus producing an inaccurate measure of cumulative exposure. Results of epidemiological studies regarding cancer risk in other organs are limited and inconsistent. epidemiological studies updated or published after IARC 2006 evaluation indicate that: no increase in cancer risk is apparent among miners and millers of asbestos-free talc; risk for ovarian cancer increases following the perineal use of commercial talcum powder. A correlation between indicators of quantity of use and cancer risk is suggested by a number of studies. The composition of talcum powders considered in such studies is not known.

Enhancement of Spices’ Inherent Characteristics Using Mid-Infrared Ray – A Pioneering Research

Spices are vital ingredients in cuisine, traditional medicine, pharmaceutical, and nutraceutical industries. Increasing the potency of the organoleptic properties of spices may reduce the quantity of use, hence conserving natural resources and reducing cost. However, the technology to accomplish this has not yet been developed. We have invented a 2-6 μm Mid-Infrared Generating Atomizer (MIRGA), which was applied externally over packaged spices. We discovered the changes in spices’ chemistry which was responsible for their enhanced inherent characteristics (aroma and taste). In addition, the required quantity of the treated spices for recipe preparation was 20-40% less versus control. The irradiation using MIRGA is economical, easy to use at any level from consumer to industry, safe and eco-friendly. The research is illustrated with organoleptic tests, instrumental measurements and mineral estimation of black cumin.

Error Enhancement for Upper Limb Rehabilitation in the Chronic Phase after Stroke: A 5-Day Pre-Post Intervention Study.

A large proportion of chronic stroke survivors still struggle with upper limb (UL) problems in daily activities, typically reaching tasks. During three-dimensional reaching movements, the deXtreme robot offers error enhancement forces. Error enhancement aims to improve the quality of movement. We investigated clinical and patient-reported outcomes and assessed the quality of movement before and after a 5 h error enhancement training with the deXtreme robot. This pilot study had a pre-post intervention design, recruiting 22 patients (mean age: 57 years, mean days post-stroke: 1571, male/female: 12/10) in the chronic phase post-stroke with UL motor impairments. Patients received 1 h robot treatment for five days and were assessed at baseline and after training, collecting (1) clinical, (2) patient-reported, and (3) kinematic (KINARM, BKIN Technologies Ltd., Kingston, ON, Canada) outcome measures. Our analysis revealed significant improvements (median improvement (Q1-Q3)) in (1) UL Fugl-Meyer assessment (1.0 (0.8-3.0), p < 0.001) and action research arm test (2.0 (0.8-2.0), p < 0.001); (2) motor activity log, amount of use (0.1 (0.0-0.3), p < 0.001) and quality of use (0.1 (0.1-0.5), p < 0.001) subscale; (3) KINARM-evaluated position sense (-0.45 (-0.81-0.09), p = 0.030) after training. These findings provide insight into clinical self-reported and kinematic improvements in UL functioning after five hours of error enhancement UL training.

Measuring Smartphone Use: Survey Versus Digital Behavioral Data

While digital technology use and skills have typically been measured with surveys, digital behavioral data that are passively collected from individuals’ digital devices have recently emerged as an alternative method of measuring technology usage patterns in a more unobtrusive and detailed way. In this paper, we evaluate how passively collected smartphone usage data compare to self-reported measures of smartphone use, considering the three usage dimensions amount of use, variety of use, and activities of use. Based on a sample of smartphone users in Germany who completed a survey and had a tracking app installed on their smartphone, we find that the alignment between the survey and digital behavioral data varies by dimension of smartphone use. Whereas amount of use is considerably overreported in the survey data, variety of use aligns more closely across the two data sources. For activities of use, the alignment differs by type of activity. The results also show that the alignment between survey and digital behavioral data is systematically related to individuals’ sociodemographic characteristics, including age, gender, and educational attainment. Finally, latent class analyses conducted separately for the survey and digital behavioral data suggest similar typologies of smartphone use, although the overlap between the typologies on the individual level is rather small.

Variability and patterns in children's media use and links with language development.

Media use is widespread and rising, but how often and for what purpose young children use media varies, which has differential impacts on development. Yet little work has measured how and why children under 36 months use digital media or media's consequences for language. The current study measures how and why 17- to 30-month-old children use digital media and associations with their language abilities. The amount of use, type of activity and caregiver reasons for children's media use were then compared to the child's vocabulary and mean length of utterance. About 17- to 30-month-old children are primarily exposed to TV/videos over other media forms, which are often used to occupy children. Video time (but not other activities) negatively predicts children's language. The negative impact of videos on vocabulary persists regardless of the reason for use, however, the effect of videos on expressive language may be tempered when videos are used for education or connecting. Children under 36 months are using digital media at high rates. What they are doing and why they use media is critical to predict the effect it might have on language development. Further research and anticipatory guidance on the consequences of videos are needed.

Problematic coffee use and associated factors among medical and health science students in Dilla University, Ethiopia.

Coffee holds a cherished place in Ethiopian culture, its consumption among students raises concerns despite its perceived benefits for alertness and productivity. Moderate caffeine intake remains unproblematic, but exceeding 400 mg daily can trigger detrimental health effects such as fatigue, memory impairment, and even attention-deficit disorder. Research on problematic coffee use among young adults, specifically Ethiopian students, remains limited, hindering our understanding of its potential scope and impact. To address this knowledge gap, researchers at Dilla University, Ethiopia, undertook a comprehensive study in 2022, focusing on the university's student population. This investigation holds significant potential to unveil the previously obscured landscape of excessive coffee consumption in this demographic and inform future research and potential interventions. An institutional-based cross-sectional study design was conducted in August-July, 2022. To measure problematic coffee use, this study used the Diagnostic Statistical Manual five criteria for substance use disorder. Those who scored >2 out of 11 criteria were considered to have problematic coffee use. To measure a significant association between the outcome and independent variable, a multivariable logistic regression analysis at p < 0.05 and 95% confidence interval was employed. This study included 414 respondents. More than half of the respondents, 347 (59.7%) were male. Out of all respondents, 182 (44.0%) had a boy/girlfriend. Nearly half of the respondents, 218 (52.7%) were orthodox, Christian religion followers. According to this study's findings, 137 (33.1%) respondents were considered to have problematic coffee use. Multivariable logistic regression analysis showed that 5-10 years duration of coffee use (AOR = 4.62, 95% CI: 2.96-7.85; p = 0.001), start to use coffee before joining university (AOR = 2.977, 95% CI: 1.332-6.653; p = 0.008) and 6-9 cups of daily coffee use (AOR = 3.26, 95% CI: 2.14-5.89; p = 0.00) were associated with problematic coffee use. This study showed that one-third of the respondents had problematic coffee use. The starting point, duration, and amount of use had a strong association with problematic coffee use. Hence, focusing on addressing the mental health challenges associated with problematic/excessive coffee consumption among higher education students is advisable. Additionally, promoting awareness of problematic/excessive coffee use and its potential remedies is recommended.

Efisiensi Faktor Produksi Pada Usahatani Padi Sawah Peserta dan Non-Peserta SL-PTT di Kecamatan Poelang Utara Kabupaten Bombana

Research to determine the influence of production factors and their efficiency on rice farming of SL-PTT participants and non-SL-PTT participants and non-SL-PTT participants in North Poleang Bombana District. Carried out in May – July 2011. Samples were determined using simple cluster sampling based on villages, as many as 2 villages (50% of the village population). Respondents from each village consisted of 15 participants and 15 non-participants of SL-PTT in a simple random manner (60 samples). Analysis using multiple non-linear regression using the Cobb-Douglas function and price efficiency analysis. Research results: (a) Production Factors; Land area, amount of use of seeds, fertilizer, labor and pesticides are closely related and simultaneously influence the production of lowland rice farming (R; l 0.889 and R2 = 0.790). (b) partially, except for the number of seeds, all production factors have a positive effect, but only fertilizer has a real effect, even at a confidence level of 85%. (c) Efficiency analysis shows that the use of fertilizer, labor and pesticides is not efficient so they can still be added to improve, while seeds are not efficient.

Обґрунтування та перспективи використання комах як джерела білка у кормах для риб (огляд)

Purpose. Analysis of the prospects and experience of using insects as an alternative source of animal protein in aquaculture. Scientific and practical substantiation of the introduction of black soldier fly (Hermetia illucens) into fish feeds. Evaluation of the effeciency of the use of insect protein in solving the issues of sustainable development of aquaculture. Findings. World resources and trends in the use of animal protein in feed production have been characterized. The biological and functional characteristics, as well as the quality and safety of animal protein have been analyzed. Insect protein is considered a non-traditional feed component for Ukrainian aquaculture. It should be noted that the use of insect protein in feeding different fish species requires special approaches, in accordance with the biological needs of their body and the stage of ontogenesis. Also, the efficiency of the use of insect protein in fish feeds depends on the methodological approaches of its introduction, the amount of use, as well as the feed component replaced in the basic diet. On the example of the results of scientific studies on the introduction of black soldier fly (Hermetia illucens) in fish feeds, promising directions and methods of using this insect species have been identified. The positive effect of experimental feeding on productive parameters, feed conversion, quality and safety of farmed fish products have been noted. The limiting factors for increasing insect protein production in accordance with technological parameters and biological characteristics have been analyzed in detail. It is noted that the industrial production of insects can be a solution to the problem of processing industrial and organic waste as a result of their use for nutrition. The feasibility and prospects of using insect protein in aquaculture in Ukraine have been outlined. The authors have analyzed modern sources of professional scientific literature in accordance with the study of the state and prospects of using traditional and non-traditional sources of animal protein in fish feeds. Using the example of the black soldier fly, the authors characterize the efficiency of the use of insect protein in aquaculture, its biological characteristics and technological parameters of production. Practical value. The literature review covers modern approaches and prospects for optimizing aquaculture. It can be used by fish farming specialists for scientific studies and practical experimental developments. Keywords: animal protein, insect protein, black soldier fly, Hermetia illucens, fish feeds, non-traditional feed components, tenological parameters, biological characteristics, aquaculture.