In Global Positioning System (GPS) data analyses, large networks are usually divided into sub-networks to solve the conflict between increasing amounts of data and limited computer resources, although an integrated analysis would provide better results. This conflict becomes even more critical with the increasing number of stations, and low-Earth-orbiting satellites and the Galileo system coming into operation. The major reason is that a huge number of ambiguity parameters are kept in the normal equation for sequential integer ambiguity fixing. In this paper, the problem is solved by a special procedure of parameter elimination for both real-valued and ambiguity-fixed solutions, based on an adapted ambiguity-fixing approach where the covariance-matrix of ambiguity parameters is not required anymore. It is demonstrated that, with the new strategy, the required memory can be reduced to one-tenth and the computation time to at least one-third compared to the existing methods, and huge GPS networks with several hundred stations can be processed efficiently on a personal computer.