Alveolar Crest Research Articles

Results of bone grafting using a xenogenic cortical plate BiOTECK

BACKGROUND: The fundamental condition that determines the effectiveness of treatment, with immediate and long-term positive results, is the amount of bone tissue in the jaws at the proposed implantation site. Defects in the dentition to a large extent and severe atrophy of the bone tissue of the jaws due to the loss of teeth significantly limit the use of dental implantation. It is reasonable to expand the indications for the use of dental implants in cases of atrophy of the jaw bone tissue in the installation site. This allows the optimization of surgical techniques aimed at increasing the volume of the jaw bone tissue, such as the use of new osteoplastic materials for guided bone regeneration.
 AIM: This study aimed to analyze the results of a jawbone graft using a BiOTECK xenogeneic cortical plate.
 MATERIALS AND METHODS: The test group consisted of 22 patients (11 men and 11 women) with jawbone atrophy. All patients underwent bone graft surgery using a BiOTECK xenogeneic cortical plate (BiOTECK, Italy).
 In the course of the study, all patients with jawbone loss underwent a dynamic clinical and X-ray examination during the following stages: during the dental implant surgery planning stage aimed at determining the volume of the bone tissue available and identifying the associated conditions and diseases (prior to conducting an osteoplastic procedure), prior to dental implant installation (6 months after osteoplastic surgery), and prior to the start of the orthopedic stage of treatment (12 months after osteoplastic surgery).
 RESULTS: The cone beam computed tomography data were analyzed and statistically processed to obtain the results. It was revealed that the values of the “bone densitometry” indicator increased 6 months after the bone graft using the BiOTECK xenogeneic cortical plate, and the values of the “densitometric density of jaw bone tissue” indicator increased.
 Immediately after bone grafting using the BiOTECK xenogeneic cortical plate, the thickness of the bone tissue of the upper jaw increased by an average of 5.0±0.1 mm and that of the lower jaw increased by an average of 3.9±0.1 mm. In the first stage of the dental implant surgery (6 months after osteoplastic procedure), due to resorption, the thickness of the bone tissue of the alveolar process of the upper jaw decreased by 1.1±0.1 mm and amounted to 6.8±0.1 mm (bone resorption rate: 13.9%), and the thickness of the bone tissue of the alveolar process of the lower jaw decreased by 0.8±0.2 mm and amounted to 6.6±0.3 mm (bone resorption rate: 10.3%).
 CONCLUSION: The clinical and X-ray results obtained 1 year after installing dental implants and performing bone graft surgery using the BiOTECK xenogeneic cortical plate indicate a stable volume of marginal bone tissue in the area of alveolar crest reconstruction.

Evaluating risk factors and complications in mandibular ramus block grafting: a retrospective cohort study

ObjectivesThis retrospective cohort study aimed to identify the complications and risk factors associated with alveolar grafting using autologous mandibular ramus grafts, guided by the research question: What are the complications encountered in patients undergoing alveolar bone grafting using autologous mandibular ramus block and what are the risk factors associated with the development of these complications?Materials and methodsThe study included 70 patients who underwent alveolar crest augmentation with autologous mandibular ramus block grafting. Intraoperative, early postoperative, and late postoperative complications were analyzed, as were various risk factors.ResultsThe results showed that the majority of patients had successful outcomes with minimal complications. Sex was found to significantly influence the visibility of the inferior alveolar nerve (IAN). Early postoperative complications were associated with IAN visibility and the use of a single screw for graft fixation. Late postoperative complications were significantly associated with the presence of infection.ConclusionThe findings emphasize the importance of careful surgical techniques, infection prevention, and patient selection in minimizing complications.Clinical relevanceThis article may contribute to clinicians’ and so patients’ understanding of potential risk factors associated with over all ramus block grafting procedure. Based on this information, clinicians can also improve their ability to manage risk factors and associated complications and compare ramus block grafting with other alternatives to determine the best treatment approach for that particular patient.

Radiographic evaluation of the distance between the restoration margin and the alveolar bone crest in dental implant patients: A retrospective study

ObjectivesThe recently introduced Implant Disease Risk Assessment (IDRA) identifies a restoration margin-alveolar bone crest (RM-AC) distance of less than 1.5 mm as a key risk factor for peri‑implant disease among eight major risk factors. This study evaluated the impact of the RM-AC distance on marginal bone loss (MBL) through radiographic analysis. MethodsThis retrospective cross-sectional study included 77 partially edentulous patients (39 females and 38 males, aged 22 to 76 years) with 202 platform-switched conical connection implants, cement-retained, implant-supported fixed restorations, and bone-level implants placed between 2016 and 2021. Dental implants were followed for least 6 to 36 months at follow up functional loading. Study participants were categorized into Group A (RM-AC distance ≤ 1.5 mm, n = 69) and Group B (RM-AC distance > 1.5 mm, n = 133). Twelve patients in Group B and five patients in Group A had no history of periodontal disease. The MBL was measured radiographically from the most coronal point of the implant shoulder to the alveolar bone, and the RM-AC distance was measured from the restoration margin to the alveolar crest. Multinomial logistic regression analysis was used for statistical evaluation. ResultsThe incidence of MBL in Group A was statistically significant and 3.42 times higher than that in Group B. The rate of MBL in periodontitis Stage 4 was found to be 26.31 times higher than that in periodontitis Stage 2. The incidence of MBL was 6.097 and 5.02 times higher with increasing implant diameter and length, respectively. ConclusionThis study conclusively demonstrates that RM-AC distance ≤ 1.5 significantly increases the risk of MBL, particularly in patients with a history of periodontal disease. Clinical significanceThis study highlights the critical role of maintaining an RM-AC distance greater than 1.5 mm in the prevention of MBL, particularly in patients with a history of periodontal disease. Since implant diameter and length have a significant impact on the risk of MBL, it emphasizes that implant demographics should also be carefully evaluated.

Efficiency of osseodensification versus screw expansion technique for augmentation of narrow alveolar ridges: A comparative clinical study

Background: Alveolar ridge expansion is proposed when the alveolar crest thickness is ≤5 mm. The screw expansion technique has been utilized for many years to expand narrow alveolar ridges. Recently, the osseodensification technique has been suggested as a reliable technique to expand narrow alveolar ridges with effective width gain and as little surgical operating time as possible. The current study aimed to compare osseodensification and screw expansion in terms of clinical width gain and operating time. Materials and methods: Forty implant osteotomies were performed in deficient horizontal alveolar ridges (3–5 mm). A total of 19 patients aged 21–59 years were randomized into two groups: the screw expansion group, which involved 20 osteotomies performed by screw expander drills, and osseodensification group, which comprised 20 osteotomies achieved by osseodensification drilling technique. One millimetre below the alveolar bone crest was measured with a bone caliper at two intervals (before implant osteotomy and after implant osteotomy), and operating time was assessed. Results: Before expansion, the mean alveolar ridge width was 4.20 ± 0.71 mm in the osseodensification group and 4.52 ± 0.53 mm in the screw-expansion group. No statistically significant difference in alveolar bone width before expansion was found between the groups (P > 0.05). After the expansion of the alveolar ridge with osseodensification or screw expansion techniques, the average ridge width was 5.48 ± 0.57 mm in the osseodensification group and 5.71 ± 0.53 mm in the screw-expansion group. Difference in width gain postoperatively between the groups was 0.09 mm, which was not statistically significant (P > 0.05). According to operating time, osseodensification consumed 6.21 ± 0.55 minutes, and screw expansion required 16.32 ± 0.60 minutes for a single implant with a significant difference between the groups (P < 0.0001). Conclusion: Alveolar bone expansion by osseodensification showed comparable width gain and less surgical operating time compared with expansion by screw expansion technique.

Alveolar Buccal Bone Overbuilding Before Tooth Extraction: A Preclinical Study.

To evaluate the dimensional changes in the alveolar crest after buccal overbuilding was performed prior to tooth extraction in a dog model. At the test sites, alveolar crest overbuilding was performed on the buccal aspect of the distal root of the third premolar using xenograft covered with a collagen membrane. No treatment was applied at the control sites. After 3 months, the distal roots of both third premolars were extracted and implants were immediately placed into the alveolus, allowing nonsubmerged healing. After 3 months, biopsy samples were collected. Upon histologic analysis, no statistically significant differences in hard tissue dimensions were found. The buccal bone plate at the test sites presented a tendency for higher resorption compared to the control sites. However, if the contribution of the residue of biomaterial is considered, a higher volumetric gain was registered at the test than at the control sites. The buccal overbuilding performed prior to tooth extraction did not contribute to the preservation of the alveolar crest dimensions after extraction. This could be due to failure to incorporate the graft into the newly formed bone.

Mandibular canal assessment in dentate and edentulous ridges of 400 Iraqi Arab and Kurdish populations using cone beam computed tomography

ObjectivesThis study aims to compare differences in mandibular canal (MC) location between dentate and edentulous ridges, in the second premolar region as well as the first, second, and third molar regions using cone beam computed tomography (CBCT) of Arabic and Kurdish Iraqi populations. Materials and MethodsCBCT images of 400 subjects (200 Arabs, 200 Kurds) were collected from radiological archives. RadiAnt DICOM software (Medixant, Poland) was used for image analyses. Measurements were performed from MC to buccal and lingual alveolar crests and to buccal, lingual, and inferior aspect of the mandible for both dentate and edentulous ridges. Additionally, distance to the most superior aspect of residual edentulous ridge were performed. Independent t-test and Mann-Whitney U Test were performed utilising SPSS v.26. ResultsDistances from MC to buccal and lingual alveolar crests were consistently lower in edentulous ridge compared to dentate ridge across all teeth regions. Distances to lingual and inferior border of the mandible were higher in edentulous ridge compared to dentate ridge of all teeth regions. Distances to buccal surface of the mandible varies with fluctuations of dentate and edentulous ridges displaying higher measurements. Distance to superior aspect of residual edentulous ridge revealed mean values in the range of 13.45 to 15.69 mm in Arabs and 13.96 to 16.37 mm in Kurds. ConclusionsDiscrepancy in vertical position of MC was observed between dentate and edentulous ridges within Arab and Kurd populations. Horizontal position of MC was unaffected by tooth loss and found to be closer to lingual surface of all molars. The residual alveolar ridge was sufficient to accommodate the common length and width of dental implants. Clinical significanceThe findings could play a crucial role in planning surgical interventions of the mandible, helping to prevent complications that might arise due to inadequate preoperative assessments.

Periodontitis and alveolar resorption in human skeletal remains: The relationship between quantitative alveolar bone loss, occlusal wear, antemortem tooth loss, dental calculus and age at death in a low socioeconomic status, modern forensic human collection from Yucatan

ObjectiveThis paper assesses the relationship between the distance between the cemento-enamel junction and alveolar crest and risk factors commonly associated with periodontitis. MaterialsEighty individuals between 28 and 92 years old with known biological sex and age were analyzed from a 20th century forensic human collection from Merida, Yucatan (Mexico). MethodsMacroscopic assessment, along with metric analysis, was employed using a probe. ResultsAnte-mortem tooth loss was positively correlated with the distance between the cemento-enamel junction and alveolar crest, as was the presence of root calculus in females. ConclusionsCemento-enamel junction to alveolar crest distance is not a reliable indicator of periodontitis since it is not directly related to periodontitis-causing infectious pathogens, and since ante-mortem tooth loss can affect root exposure. SignificanceThis study demonstrates that a purely quantitative approach to diagnosing periodontitis in archaeological and forensic human remains can be misleading. LimitationsThe skeletal collection is only representative of the low socioeconomic class of Merida, and its female cohort is underrepresented. In addition, because the Xoclan collection is modern, limitations (particularly with respect to tooth wear) of the applicability of these interpretations to older archaeological remains exist. Suggestion for further researchA combination of quantitative and qualitative characteristics of alveolar bone is needed to reliably diagnose periodontitis in skeletal populations.

Anatomical study on the posterior alveolar canal in maxillary tuberosity region using computed tomography

ObjectiveThis study aimed to identify the anatomical characteristics of the posterior alveolar canal (PAC) and related maxillary bone using computed tomography (CT). MethodsThe study included 40 Japanese cadavers (70 hemi-heads), comprising 23 males (41 hemi-heads) and 17 females (29 hemi-heads). Simple CT data of the maxillary bone region of the specimens were obtained and analyzed using a measurement software with reference to the Frankfurt horizontal (FH) plane to identify the PAC in the maxillary tuberosity region, alveolar crest (AC), and corner of the inferior crest of the zygomatic process (CICZP). The shortest distances between the PAC and the respective landmarks and the smallest width of the posterior wall of the maxillary sinus (WPWMS) at the PAC level were calculated and analyzed statistically. ResultsOf all specimens, the mean and SD of AC-PAC: 21.4 ± 3.32 mm, horizontal PAC-CICZP: 15.1 ± 2.89 mm, vertical PAC-CICZP: 5.70 ± 3.15 mm, WPWMS: 0.81 ± 0.31 mm, and the coefficients of variation ranged 15.5–55.3%. In the WPWMS, the mean value was statistically smaller in the female group (0.59 mm) than in the male group (0.96 mm) (p < 0.001). ConclusionsThe results showed certain tendencies in the distances between the PAC and the respective anatomical landmarks with large variations. The thickness of the posterior wall of the maxillary sinus was thinner in females than in males. However, it is < 1 mm in both sexes, and external forces caused by trauma or surgery may fracture the posterior wall of the maxillary sinus and damage the posterior superior alveolar artery regardless of sex.

Influence on marginal bone levels at implants equipped with blades aiming to control the lateral pressure on the cortical bone. An experimental study in dogs.

To avoid cortical compression, several implant systems have included in the protocol dedicated drills aimed at widening the cortical region of osteotomy. However, the manual execution of this operation does not guarantee the necessary precision. Hence, the present study aimed to determine the optimal size of the recipient site at the level of the alveolar crest in relation to the size of the coronal region of the implant to achieve the best healing result. Blades of different diameters were incorporated into the coronal part of the implant to prepare the cortical region of the mandibular alveolar bone crest in different dimensions in relation to the collar of the implant. The differences in diameter of the blades in relation to the collar of the implant were as follows: one control group, -175μm, and three test groups, 0μm, + 50μm, or + 200μm. The marginal bone loss (MBL) at the buccal aspect was 0.7mm, 0.5mm, 0.2mm, and 0.7mm in the - 175μm, 0.0μm, + 50μm, + 200μm groups, respectively. The differences were statistically significant between group + 50μm and control group - 175μm (p = 0.019), and between + 50μm and + 200μm (p < 0.01) groups. The level of osseointegration at the buccal aspect was more coronally located in the test groups than in the control group, whereas the bone-to-implant contact percentage was higher in the + 50μm and + 200μm groups. However, these differences were not statistically significant. The lowest bone crest resorption and highest levels of osseointegration were observed in the 0.0μm and + 50μm groups. The cortical region where the blades had performed their cutting action showed regular healing with perfect hard and soft tissues sealing in all the groups. Cortical blades gathered bone particles, particularly in the + 200μm group, which were incorporated into the newly formed bone. The results from the present experiment provide support to the use of blades that produce a marginal gap of 50μm after implant insertion.

The Influence on Osseointegration of Immediate Functional Loading on Single Crowns: A Randomized, Double-Blind, Split-Mouth Controlled Clinical Trial with Histomorphometric Evaluation.

To evaluate the influence of immediate loading on the osseointegration and bone density of implants placed in a healed alveolar bone crest and supporting single crowns. Two solid titanium transmucosal miniimplants were placed in the distal regions of the mandible in 14 patients. One mini-implant was immediately functionally loaded, whereas the other was left unloaded. After 2 months of healing, biopsy samples were retrieved and the levels of new bone, old bone, and total bone (new &#43; old) were assessed. Histologic examination was performed on biopsies from 12 patients (n &#61; 12). The new bone-to-implant contact percentage (BIC%) was 40.3% ± 16.8% and 55.1% ± 19.1% (P &#61; .043) at the unloaded and loaded sites, respectively; in addition, the total BIC% was 44.9% ± 17.0% and 59.5% ± 18.8%, respectively (P &#61; .034). The new bone density was 45.9% ± 11.6% for the unloaded implants and 45.9% ± 16.7% for the loaded implants (P &#61; .622). Immediate loading had a positive effect on bone apposition at the implant surface, but no effect on bone density was observed after 2 months of healing.

The repeatability of periodontal imaging with intraoral ultrasound scanning.

Ultrasound is a non-invasive and low-cost diagnostic tool widely used in medicine. Recent studies have demonstrated that ultrasound imaging might have the potential to be used intraorally to assess the periodontium by comparing it to current imaging methods. This study aims to characterize the repeatability of intraoral periodontal ultrasound imaging. Two hundred and twenty-three teeth were scanned from fourteen volunteers participating in this study. One operator conducted all the scans in each tooth thrice with a 20MHz intraoral ultrasound. The repeatability of three measurements, alveolar bone crest to the cementoenamel junction (ABC-CEJ), gingival thickness (GT), and alveolar bone thickness (ABT), was calculated with intercorrelation coefficient (ICC). Measurements were also compared with mean absolute deviation (MAD), repeatability coefficient (RC), and descriptive statistics. ICC scores for intra-rater repeatability were 0.917(0.897,0.933), 0.849(0.816,0.878), and 0.790(0.746,0.898), MAD results were 0.610mm (± 0.508), 0.224 (± 0.200), and 0.067 (± 0.060), and RC results were 0.648, 0.327, and 0.121 for ABC-CEJ, GT, and ABT measurements, respectively. Results of the present study pointed towards good or excellent repeatability of ultrasound as a measurement tool for periodontal structures. Clinicians could benefit from the introduction of a novel chairside diagnostic tool. Ultrasound is a non-invasive imaging assessment tool for the periodontium with promising results in the literature. Further validation, establishment of scanning protocols, and commercialization are still needed before ultrasound imaging is available for clinicians.

Horizontal ridge augmentation in the maxillary aesthetic region using the autogenous circular cortical-lamina anchoring technique: A case series study.

This case series aimed to evaluate the effectiveness of the autologous circular cortical lamina-anchoring (CCA) technique for horizontal bone augmentation in the maxillary aesthetic region. A total of 25 patients with 28 implants underwent horizontal bone augmentation using CCA followed by implant placement and crown delivery. The primary outcome measures were alveolar ridge width (ARW) and buccal bone thickness (BBT), whereas the secondary outcome measures included marginal bone loss (MBL), mid-facial mucosal margin loss (MML), clinical assessment of peri-implant and aesthetic parameters, patient-reported outcome measures (PROMs), and implant survival rates. All 25 patients with 28 implants completed the treatment, no dropouts occurred. After CCA, the mean ARW at 1, 2, and 4 mm below the alveolar crest significantly increased from 2.38 ± 0.48, 2.85 ± 0.51, and 3.21 ± 0.53 mm to 6.80 ± 0.48, 6.99 ± 0.50, and 8.08 ± 0.52 mm, respectively. At the 3-year follow-up, the mean BBT0, BBT2, and BBT4 slightly decreased from 2.51 ± 0.26, 2.63 ± 0.31, and 2.75 ± 0.29 mm to 2.43 ± 0.27, 2.51 ± 0.30, and 2.64 ± 0.28 mm, respectively. Although the overall MBL was <0.15 mm, the results were statistically significant. The mean MML at the 3-year follow-up was 0.02 mm. All implant sites showed acceptable peri-implant and aesthetic outcomes. Incisions healed without complications, and no significant differences in PROMs observed at any time point. The 3-year follow-up showed a 100% implant survival rate. The autologous CCA technique is a useful method for increasing ARW and maintaining BBT in the maxillary aesthetic region.

Does the sagittal root position of maxillary anterior teeth affect the decision making on immediate implants in the anterior maxilla? A CBCT-based study.

Immediate implant placement in the maxillary esthetic zone is a challenging and demanding task. To achieve favorable results, proper case selection and treatment planning are necessary. Variables like the sagittal root position (SRP) and the labial bone thickness (LBT) of maxillary anterior teeth are of paramount importance for predictable outcomes. The aim of the present study was to evaluate the SRP and LBT of maxillary anterior teeth in the context of immediate implant placement by using cone-beam computed tomography (CBCT) in a sample of the Pakistani population. A cross-sectional study was conducted using the CBCT scans of patients. The SRP of each tooth (maxillary canine to canine) was evaluated in the sagittal section of a CBCT scan according to the classification by Kan et al. The LBT of each tooth was measured perpendicularly to the long axis of tooth at 3 sites: at the alveolar crest (P1); 2 mm from the alveolar crest (P2); and 4 mm from the alveolar crest (P3). Descriptive statistics were reported for SRP and LBT. The χ2 test was employed to assess any association between the variables. Class I SRP was the most prevalent (n = 196, 81.7%), while Class III was the least frequent (n = 1, 0.4%). The association between the tooth type and SRP was statistically non-significant (p = 0.510). In the evaluated sample of the Pakistani population, the most frequent type of the SRP of maxillary anterior teeth was Class I, which is most favorable for immediate implant placement. Furthermore, the labial bone in the maxillary esthetic zone was found to be mostly thin - LBT was within the range of 0.5-0.9 mm - which makes immediate implant placement in the anterior maxilla a challenge. The results of the present study could serve as a guide for clinicians in terms of appropriate patient selection for immediate implant placement in the maxillary esthetic zone.

Evaluation of Optimal Insertion Sites and Angles for Orthodontic Mini-Implants at the Anterior Nasal Spine Region Based on Cone-Beam Computed Tomography

Background: To infer the optimal angulation and height level of mini-implant insertion in the anterior nasal spine (ANS) region from alveolar bone depth (BD) and labial cortical bone thickness (CBT) through cone-beam computed tomography (CBCT), the influences of sex, age, and growth pattern on BD, CBT, and the starting point of the ANS were examined. Material and methods: BD and CBT were measured on CBCT median sagittal images at specific angles (0, 15, 30, 45, and 60 degrees) to simulate the angulation of insertion. The height level of the first axial image with obvious bone ridge was recorded as the start of ANS. Results: The average height of ANS start was 9.42 mm from the alveolar bone crest between the central incisors. The variations in height level and insertion angle combined, or either of them individually, significantly influenced BD and CBT, demonstrating overall decreasing trends (p &lt; 0.001). BD was not influenced by sex, age, or growth pattern (p &gt; 0.05). However, CBT was found to be correlated with sex and growth pattern, while the height level of ANS start was associated only with growth pattern, particularly in hypodivergent patients (p &lt; 0.05). Conclusion: The recommended insertion height level is 14–16 mm from the alveolar bone crest and the recommended angulation is 30–45°. An innovative inequity in the relationship between a certain height level and the insertion angulation is proposed.

Evaluation of maxillary transverse dimensions in individuals with a unilaterally impacted canine.

The aim of this study was to investigate the maxillary width within individuals with a unilaterally impacted maxillary canine and to determine any association between the impacted canine location and some canine-related variables. A cross-sectional analytical study using a split-mouth design included 22 CBCTs of individuals with unilaterally impacted maxillary canines (a total of 44 sides). The maxillary width was measured and compared in both impacted and non-impacted sides at various levels: basal, alveolar, and dental. The following canine-related variables were analyzed and compared with impaction location: impacted canine angulation, cusp tip distance from the occlusal plane, type of impaction (vertical or horizontal), presence of root resorption, deciduous teeth, or adjacent teeth transposition. Significance was considered at P < 0.05. There was a significant reduction in maxillary width on the impacted side at the following levels: maxillary first premolar alveolar crest in both coronal and axial sections, dental width measured from the central fossa of maxillary first molar to the midline, and width measured from the canine cusp tip to the midline. Moreover, the distance from the palatally impacted canine cusp tip to the occlusal plane was statistically significantly lower (7.6 ± 1.5 mm) compared to buccal (10.8 ± 3.3 mm) and mid-alveolus (12.0 ± 3.9 mm) impaction, (P values = 0.02). There was a significant association between canine impaction and reduction in the maxillary width at least on the dental level. The palatally impacted canine cusp tip was significantly closer to the occlusal plane compared to the buccal and mid-alveolar impaction.

Efficacy of autologous platelet concentrate products for alveolar preservation: A meta-analysis.

The purpose of the study was to systematically evaluate the efficacy of autologous platelet concentrate products in the preservation of the alveolar ridge after tooth extraction through meta-analysis and provide a theoretical basis for the clinical application of autologous platelet concentrates to reduce alveolar bone resorption. This study conducted a meta-analysis of clinical trials between 2013 and 2023, focusing on autologous platelet concentrate products (e.g., PRP, PRF, CGF, and PRCF) used for alveolar ridge preservation after tooth extraction. The analysis included 122 articles and 371 extraction sockets. All statistical analyses were performed using Review Manager version 5.4. Results indicate that these platelet concentrates effectively reduced changes in horizontal width 1 mm below the alveolar crest and vertical socket height. They also promoted a higher percentage of new bone formation in extraction sockets compared with control groups. However, they did not significantly prevent horizontal bone resorption at 3 and 5 mm below the alveolar crest. In conclusion, autologous platelet concentrates are useful for alveolar ridge preservation, but larger clinical studies are needed to confirm these findings due to the relatively small sample size in this study.

Clinical and Radiographic Evaluation of Calcium Phosphate-Poly(lactide-co-glycolide) Graft in Regeneration of Intrabony Defects: Randomized Control Trial.

This study aims to evaluate the efficacy of calcium phosphate-poly(lactide-co-glycolide) composite graft in the regeneration of intrabony defects in chronic periodontitis patients over a period of 12 months. A total of 11 systemically healthy chronic periodontitis patients with 22 graftable sites were treated with calcium phosphate cement (CPC) bone graft (control group) and CPC-poly(lactic-co-glycolic acid)(PLGA) composite (test group) after flap reflection and debridement. Clinical parameters such as probing pocket depth (PPD) and clinical attachment level (CAL) were recorded at baseline and 3, 6, 9, and 12 months. Bone probing depth (BPD) and radiographic parameters such as defect depth (DD), changes in alveolar crest level (ALR), defect depth reduction (DDR), and percentage in defect depth reduction (PDDR) were calculated at baseline, and 6 and 12 months. The data were recorded and statistically analyzed. On intragroup comparison, there was a significant improvement in all the parameters over a period of 1 year (clinically and radiographically). However, there was no statistically significant difference between the two groups in any of the parameters though there was a slightly higher bone fill noted in the test group. Even though the CPC-PLGA composite bone graft showed a slight improvement in clinical and radiographic parameters as compared to the CPC graft, it was not statistically significant. A major drawback of Calcium Phosphate cements as bone grafts is their poor degradability. The PLGA microspheres degrade to expose macropores and interconnected pores in the graft substrate which in turn would promote the ingrowth of osteoblasts. Also, this composite graft is mouldable, and resorbable and has been shown to snugly fit into the defects making them a suitable scaffold material. How to cite this article: Ojha M, Pawar Chandrashekara Rao D, Gowda V. Clinical and Radiographic Evaluation of Calcium Phosphate-Poly(lactide-co-glycolide) Graft in Regeneration of Intrabony Defects: Randomized Control Trial. J Contemp Dent Pract 2023;24(12):921-927.

Mandibular changes in a patient suspected with Thalassemia trait: A case report by radiograph finding

Thalassemia is an inherited hemolytic anemia characterized by abnormal synthesis the hemoglobin globin component. A forty-year-old woman presented to a private dentist complaining of a left-sided facial pain and headache that occurred out of the blue. Panoramic radiograph showed severe caries on several teeth, generalized reduction in the alveolar crest, thin lamina dura and changes in trabecular pattern of mandible and the inferior alveolar canal on each side was partially absent. Unmanaged anemia caused ineffective erythropoiesis resulting extensive bone marrow with sparse coarse trabecular. As the mean hemoglobin falls, enhanced osteoclastic bone resorption thus thinning lamina dura, reducing alveolar crest and lacking radiopaque line of inferior alveolar canal. Panoramic is widely used in dentistry, this case report presents a case of patient discovered thalassemia through radiological findings.

Antibacterial properties of marine algae incorporated polylactide acid membranes as an alternative to clinically applied different collagen membranes

The reconstruction of bony defects in the alveolar crest poses challenges in dental practice. Guided tissue regeneration (GTR) and guided bone regeneration (GBR) procedures utilize barriers to promote bone regeneration and prevent epithelial growth. This study focuses on evaluating the antibacterial properties of marine algae-polylactic acid (PLA) composite membranes compared to commercially available collagen membranes. Marine algae (Corallina elongata, Galaxaura oblongata, Cystoseira compressa, Saragassum vulgare, and Stypopodium schimperi) were processed into powders and blended with PLA to fabricate composite membranes. Cytocompatibility assays using human periodontal ligament fibroblasts (n = 3) were performed to evaluate biocompatibility. Antibacterial effects were assessed through colony-forming units (CFU) and scanning electron microscopy (SEM) analysis of bacterial colonization on the membranes. The cytocompatibility assays demonstrated suitable biocompatibility of all marine algae-PLA composite membranes with human periodontal ligament fibroblasts. Antibacterial assessment revealed that Sargassum vulgare-PLA membranes exhibited the highest resistance to bacterial colonization, followed by Galaxaura oblongata-PLA and Cystoseira compressa-PLA membranes. SEM analysis confirmed these findings and revealed smooth surface textures for the marine algae-PLA membranes compared to the fibrous and porous structures of collagen membranes. Marine algae-PLA composite membranes show promising antibacterial properties and cytocompatibility for guided bone and tissue regeneration applications. Sargassum vulgare-PLA membranes demonstrated the highest resistance against bacterial colonization. These findings suggest that marine algae-PLA composite membranes could serve as effective biomaterials for infection control and tissue regeneration. Further in vivo validation and investigation of biodegradation properties are necessary to explore their clinical potential.Graphical

Location and Anatomic Characteristics of Mental Foramen in Dry Adult Human Mandibles

Aim: This study aims to investigate the mental foramen (MF) location, the presence of accessory MF, and the effect of dentition on morphometric parameters using dry adult human mandibles. &#x0D; Materials and Methods: A total of 249 dry adult human mandibles (116 dentate,133 edentate) were used. The location and number of the MF were recorded. The distances of the MF to the symphysis, posterior border of ramus, alveolar crest, and mandibular basis were measured. The symmetry of MF was examined. Student’s t-tests and Kolmogorov-Smirnov were used for statistical analysis. &#x0D; Results: The presence of dentition affected the relative superoinferior location of MF on the corpus. No statistical difference was detected in the anteroposterior position of the MF between dentate and edentate mandibles (p&gt;0.05). The most frequent position of the MF was the alignment of the second premolar. The prevalence of accessory MF was 4.41%, while the bilateral positioning of it was 0.40%. The symmetrical location of the MF was 83.62%. &#x0D; Conclusion: The prevalence of bilateral positioning of the accessory MF in the Turkish dry mandibles was 0.40%. The presence of dentition affected the relative location of MF on the corpus in the superoinferior aspect. The clinician should be considered different locations, and the presence of accessory foramen in the surgical and endodontic treatments.