Inhaled corticosteroids (ICS) form a major part of the available therapeutic armamentarium for treatment of crippling chronic respiratory illnesses such as bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD) over the past few decades. The World Health Organization (WHO) estimates that globally 235 million people suffer from BA and 64 million from COPD [1]. These chronic respiratory illnesses force physicians worldwide to prescribe ICS to their patients in their day to day clinical practice. ICS are claimed to predominantly possess local anti-inflammatory effects in the airways without significant systemic adverse effects, compared to oral or parenteral steroids, making them a favourable choice in managing BA and COPD. Intranasal inhalation of steroid aerosols/ powder is also useful in the management of allergic rhinitis. Although the systemic adverse effects of using ICS are claimed to be minimal in managing these chronic respiratory conditions, they do occur in a significant proportion of users, especially at high doses [2]. Suppression of the hypothalamo-pituitary-adrenal axis, adrenal insufficiency, growth retardation in children, Cushing syndrome, cataracts, thinning and bruising of the skin, infections from immune-suppression, and osteoporosis are some of the reported systemic adverse effects from the long-term use of ICS [2, 3]. The incidence of systemic effects depends on the type and dose of ICS used, the mode of ICS administration and interactions with concurrent use of other medications. The ICS molecules commonly available in the market are beclomethasone dipropionate (BDP), budesonide (BUD), fluticasone propionate (FP), Flunisolide (FLU), mometasone furoate (MF), and ciclesonide (CIC). Glucocorticoids are powerful steroid hormones secreted by the zona fasciculata of adrenal glands. Soon after the