Transient stability preventive control (TSPC), a method to efficiently withstand the severe contingencies in a power system, is mathematically a transient stability constrained optimal power flow (TSC-OPF) issue, attempting to maintain the economical and secure dispatch of a power system via generation rescheduling. The traditional TSC-OPF issue incorporated with differential-algebraic equations (DAE) is time consumption and difficult to solve. Therefore, this paper proposes a new TSPC method driven by a naturally inspired optimization algorithm integrated with transient stability assessment. To avoid solving complex DAE, the stacking ensemble multilayer perceptron (SEMLP) is used in this research as a transient stability assessment (TSA) model and integrated into the optimization algorithm to replace transient stability constraints. Therefore, less time is spent on challenging calculations. Simultaneously, sensitivity analysis (SA) based on this TSA model determines the adjustment direction of the controllable generators set. The results of this SA can be utilized as prior knowledge for subsequent optimization algorithms, thus further reducing the time consumption process. In addition, a naturally inspired algorithm, Aptenodytes Forsteri Optimization (AFO), is introduced to find the best operating point with a near-optimal operational cost while ensuring power system stability. The accuracy and effectiveness of the method are verified on the IEEE 39-bus system and the IEEE 300-bus system. After the implementation of the proposed TSPC method, both systems can ensure transient stability under a given contingency. The test experiment using AFO driven by SEMLP and SA on the IEEE 39-bus system is completed in about 35 s, which is one-tenth of the time required by the time domain simulation method.
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