Introduction: A change in airway management protocol provided the opportunity to evaluate scene airway management by air medical crew before and after the introduction of a rapid sequence induction protocol. Methods: A retrospective chart review and a descriptive study of scene trauma patients whose airway was established primarily by an air medical crew during two study periods: April 1994 through March 1995 (group 1, before rapid sequence induction) and April 1995 through March 1996 (group 2, after rapid sequence induction). Data collected included demographics, type of airway, Glasgow Coma Scale score, scene time, and outcome. The setting included a four helicopter air medical transport program using nurse/paramedic crews with a service area of 25,000 square miles in central, southeastern, and northeastern Ohio. Results: Group 1 patients ( n = 148) averaged 31.6 years of age and were primarily male (79.7%) with blunt injuries (92.6%) with an average Glascow Coma Scale score of 7.7. Group 2 ( n = 95) was similar, averaging 31.1 years of age, primarily male (77.9%) with blunt injuries (94.7%) and a Glascow Coma Scale score of 8.6. Groups 1 and 2 differed in oral endotracheal intubation rate ( 19 118 versus 36 95 [p = 0.03] ) and in scene time (15.7 minutes versus 20.1 minutes [ p = 0.0012]). The groups did not differ in rate of successful intubation or the rate of subsequent cricothyrotomy. Conclusion: Rapid sequence induction added significantly to ground time without significantly increasing intubation success rate or decreasing cricothyrotomy rate. Its use at the scene of injury may not be appropriate.