The agricultural expansion in the desert areas is one of the main objects of the national plan to meet the food requirement for the tremendous increase in population. This research work presents an approach to analyze the enormous complexity of land resources and its use and management from an agro-ecological perspective. It discusses the efficiency of land evaluation for assessing land use changes in rural areas. Wadi El Farigh in the Western Desert of Egypt, was selected as a case study. Fourteen representative soil profiles had been selected to assess the soil variation and validation for agricultural prospective of the study area. The soils of the study area were related to Entisols and were classified under subgroups Lithic Torripsamments and Typic Torripsamments. By using the GIS technique, the unsupervised and supervised method was carried out to separate the cultivated and the barren soils. Based on these classes, the obtained data were summarized. Agricultural soil capability indices have been calculated for the study area according to Storie index. Accordingly, three classes were identified, namely fair, poor and non-agricultural soils where the soil texture is the main limiting factor. On the other hand, Agricultural soil suitability indices had been calculated according to Land Use Suitability Evaluation Tool (LUSET). The obtained results revealed that the soil suitability showed that major suitability classes have been noted are , moderately suitable (S2) for all the selected crops with some exceptional cases that are highly suitable (S1) or (S3) that are marginally suitable for all selected crops, Table (6 and 7) . The areas that were represented by the soil profiles Nos.1 and 2 were moderately suitable for the Cucumber, Watermelon, Onion, Green Pepper, Sunflower, Potato, Barley, Wheat, Sorghum, Maize, Olive, Sesame and Mango. On the other hand, they are marginally suitable for Pear. The areas that are represented by the soil profiles Nos. 3 to 10 are moderately suitable for the Cucumber, Watermelon, Onion, Green Pepper, Sunflower, Potato, Groundnut, Pear, Wheat, Maize, Olive, Sesame and Mango. On contrary, they were highly suitable for Barley and Sorghum. Soil texture was the most limiting factor for all soils, units in addition to soil depth especially for the soils of profiles Nos. 1 and 2.