In this article, the purpose of the research was to study the impact of combining professional and educational activities on the indicators of stress resistance of adult students in connection with the growing importance of higher education and a large number of competencies in the labor market in order to be a competitive person. Moreover, modern society is undergoing a number of changes that are reflected in various areas of life, which additionally affects the physical and psychological health of a person. Thus, 334 people took part in the study among the respondents: 187 students in the magistracy and 147 not studying at the moment. Techniques for determining stress resistance were used - a test for stress resistance according to the method of K. Schreiner and a test for stress resistance by Holmes and Rage, as well as a method for determining neuropsychic instability "Forecast". The results showed that students in the magistracy have lower stress resistance than adults who do not study, which indicates high workloads associated with the implementation of various types of employment at the same time. For example, many adult learners have families, minor children, dependent parents, other social activities, etc. Thus, the factor of combining professional and educational activities, indeed, affects the instability to stressful experiences, indicating the urgent need to develop adaptive skills of adult respondents.