eLearning comprises the use of electronic technology to deliver an innovative teaching and learning method that is well-designed, learner-centric, interactive, and provides a supported learning environment to everyone, regardless of location or time. The adoption of eLearning had a varying trend from the point of view of individuals to societies, and even across nations. However, skills had been singled as one of the important components in the adoption, use or continuance of using eLearning systems. This study aimed at examining the influence of Skills on the intention to adopt eLearning in university institutions in Tanzania. The study involved the Open University of Tanzania (OUT) and the Hubert Kairuki Memorial University (HKMU). Furthermore, the study using an electronic web-based survey, quantitative data were collected from a total of 371 respondents, sampled using simple random, purposive, stratified, and proportional sampling techniques. Whereas, academic staff, students, and Information and Communication Technology (ICT) staff were all involved. The study used IBM SPSS Version 22 and SPSS Amos Version 23 with Structual Equation Modeling, to analyze the collected data using Descriptive Statistics, Explolatory Factor Analysis (EFA), and Confirmatory Factor Analysis (CFA). The findings indicated that Skills had positive and statistically significant influence on the intention to adopt eLearning in university institutions in Tanzania. Moreover, further results revealed that Skills accounted for 50 percent toward the intention to adopt eLearning systems. As a result of these findings, the study acclaims that, the Skills variable be added to the Theory of Planned Behaviour (TPB) as one of the independent variables, in explaining adoption, use or continue using eLearning systems, especially, in the context of the developing countries, particularly Tanzania. The study’s results, further recommend additional research in different contexts, examining the influence of skills to the intention to adopt, use or continuing using eLearning systems in which the new TPB model in which skills would be included as one of the independent variables.