The article analyzes the features of regional economy in the South of Russia, which is characterized by the diversity of agricultural enterprises. The paper shows that enterprises of the agro-industrial complex tend to integration in order to ensure the continuity of agricultural processes. The article studies the factors of regional development as an objective precondition for the formation of highly efficient clusters in the agro-industrial complex. The author proves that implementing the continuous scenario of the economy development and import substitution process is caused by a number of reasons including a low reaction rate to changes in market conditions; difficulties in obtaining loans; high tariffs for the transportation of agricultural products; changes in taxation. The paper determines that uniting agricultural enterprises in the agro-industrial cluster provides system benefits and guarantees a synergistic effect in the following forms: transforming the sectoral structure in the agro-industrial complex; creating the conditions for simultaneous improvement of performance indicators in cluster enterprises and administrative-territorial entities, within which enterprises are located; the organization of the agro-industrial cluster as a closed contour and, through this, reducing total costs and optimizing taxation of cluster enterprises; creating the mechanism of effective interaction with territorial authorities in implementing the regional import substitution policy; expanding access to new technologies and staff training in order to respond faster to changing market conditions in accordance with the requirements of the modern economy.
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