Background and Objectives: Healthcare systems are under increasing pressure to deliver a high quality care. To assist with this delivery, hospitals often participate in data registries. The American Heart Association’s Get With The Guidelines® modules are an in-hospital suite of programs designed to improve quality of care, adhere more closely to evidence-based guidelines, and improve patient outcomes. The objective of this study was to determine factors that influence the adoption of GWTG or other quality improvement registries in Midwest (IA, IL, IN, KS, MI, MN, MO, ND, NE, SD, WI) hospitals. Methods: Data was collected via an online survey tool. The tool consisted of 8 questions, consisting of 6 rank order or fill in the blank and 2 demographic questions. Communication about the survey and a link to it was distributed via email to 1100 participants at 726 facilities across the Midwest. The survey was available to hospitals for 1 month. Results: The survey was completed by 260 individuals, giving a response rate of 23.6%. Quantities of returned surveys were proportional to the population in each surveyed state. Job titles of respondents were predominantly Administrative Service Line Directors, Nurses, C-Suite Personnel, Quality Improvement Personnel and Physicians. Questions focused on the following: elements considered during the purchase of a registry, reasons for the retention and continued use of a data registry, Full Time Equivalent (FTE) and other operational costs tied to Return on Investment (ROI), and the identification of which department is responsible for the final approval and acquisition of a data registry. Calculations clearly demonstrated three primary factors influenced the selection and continued use of a data registry - (1) Cost of acquiring and operating the tool, (2) Ease of use and tool functionalities, and (3) Registry purchasing decisions are typically made at the C-Suite level. Conclusions: This survey was designed to examine hospital motivations, barriers and deterrents when considering data registry implementation. Ease of use, data mapping capabilities and reporting functions were consistently ranked highest in importance from most respondents. It is evident as well that the cost of acquiring and operating a registry are primary concerns of hospitals and the final decision to engage in a registry rests with C-Suite personnel. This correlates closely to the desire to lower operating costs and larger ROI through efficient and effective tool usage. Resultingly, building strategies to address financial returns on investment is imperative to engage hospitals. Specific strategies towards addressing the needs and concerns of C-Suite personnel are critical if quality improvement data registry implementation is to occur.