Adhesive Glue Research Articles

Os Styloideum Resection Complicated by Severe Contact Dermatitis to 2-Octyl Cyanoacrylate: A Case Study

We report the case of a 29-year-old man who developed severe dermatitis following surgical removal of a right dorsal hand mass at the base of the third metacarpal, which had been slowly enlarging and causing pain for 18 months. After unsuccessful conservative management, the mass was resected and the incision was closed with buried monofilament suture and 2-octyl cyanoacrylate skin glue. Upon splint removal due to pain, 6 days postoperatively, severe contact dermatitis resulting in scattered partial- and full-thickness skin necrosis was observed. Local wound care, systemic corticosteroids, and a secondary surgical closure were required for resolution of the skin breakdown. This case demonstrates 2 uncommon occurrences: a rare hand mass and severe contact dermatitis to 2-octyl cyanoacrylate with resultant tissue necrosis. Mass resection is commonly reserved for symptomatic os styloideum. Caution should be used when applying 2-octyl cyanoacrylate under a splint. Removal of glue and steroids provides effective treatment for severe contact dermatitis, but full-thickness injuries may require debridement and secondary closure.

Perineal skin tear repair following vaginal birth; skin adhesive versus conventional suture – a randomised controlled trial

This was a prospective randomised controlled trial comparing the effects of first-degree perineal tear repair using adhesive glue versus conventional suturing in terms of pain score, wound complication and patient’s satisfaction. One hundred and twenty one women were randomised. The skin adhesive group had a significantly lower pain score at rest as well as during sitting, walking and micturition during the first week of delivery compared to the suture group. The time taken to become pain free was significantly shorter in the tissue adhesive group (3.18 vs. 8.65 days, p < .001). Only two patients who had skin glue experienced wound gaping. No significant difference was observed in the level of satisfaction between the adhesive and suture groups. Tissue adhesive is better than subcuticular suture for repairing first-degree perineal tear as it causes less pain and has shorter recovery time. Impact statement What is already known on this subject. First- and second-degree tears following vaginal delivery are common and involved a third of women. Suturing of these tears is advocated to avoid wound gaping and poor healing. What the results of this study add. For first-degree tear repair, tissue adhesive is better than conventional suture in terms of pain reduction and recovery time. What the implications are of these findings for clinical practice and/or further research. Skin adhesive is an ideal method for first-degree perineal tear repair especially in out of hospital settings such as home birth or midwifery-led centre. A larger scale study is needed to establish its feasibility for second- and third-degree tears repair.

Development and research of a label caseine adhesive for packaging the industrial and household products

A new composition of the environmentally friendly water-based casein adhesive glue with the increased adhesion to the substrate (glass, polyethylene terephthalate, etc.) and the improved water resistance has been developed and explored. The glue is easily washed away when labeling products that are packaged in reusable containers, but, at the same time, possesses high adhesion to different surfaces. The optimal formulation for the developed glue adhesive composition based on casein has been determined with the help of the investigated properties. The effect of the amount of a modifying additive on the dynamic viscosity at different deformation rates, the stickiness of the adhesive composition, and the hydrogen ions index (pH) has been studied. Such technological properties of the glue adhesive composition were investigated as viscosity – 170 Pa∙s; pH – 7.21; the mass share of dry residue – 38.2 %; stickiness – 58.17 a.u.; working temperature – +20…+25 °С. The optimal technological parameters for using the glue have been defined: optimal viscosity, from 130 Pa∙s to 170 Pa∙s; temperature, 25 °C, and 35 °C, respectively. The adhesive strength between a paper label and glass is 4 points, polyethylene terephthalate – 3 points. The operation properties were assessed based on the resistance of the glue adhesive composition against changes in temperature and environmental conditions, humidity, and mechanical impact. The requirements for the glue adhesive have been stated that are to be taken into consideration in its operation: resistance against the condensed and icy water and the ability of the label to be removed from the surface of the container in a washing machine at a temperature of 70–80 °C. The glue adhesive composition was examined by a SAB Miller method to assess its quality during an ice water resistance test. A copy paper method was used to assess the label gluing quality. The requirements for the glue adhesive have been defined, which should be taken into consideration in its operation (the resistance against the condensed and icy water and the removal of a label in a washing machine at a temperature of 70–80 °C with the addition of NaOH or surface-active substances)

Nurses' and surgeons' views and experiences of surgical wounds healing by secondary intention: A qualitative study.

To explore surgeons' and nurses' perspectives of managing surgical wounds healing by secondary intention. Every year, more than 10 million surgical operations are performed in the NHS in the UK. Most surgical wounds heal by primary intention, where the edges of the wound are brought together with staples, sutures, adhesive glue or clips. Sometimes wounds are deliberately left open to heal, from the base up, known as "healing by secondary intention." These wounds are often slow to heal, prone to infection and complex to manage. A qualitative, descriptive approach, using semi-structured interviews. Interviews with five (general, vascular and plastic) surgeons and 7 nurses (3 tissue viability nurses, 2 district and 1 community nurse, and 1 hospital nurse) working in hospital and community care settings in two locations in the north of England. Data analysis followed the recommended sequential steps of "Framework" approach. Consolidated criteria for reporting qualitative research guided the study report. Participants reported that the main types of wounds healing by secondary intention that they manage are extensive abdominal cavity wounds; open wounds relating to treatment for pilonidal sinus; large open wounds on the feet of patients with diabetes; and axilla and groin wounds, associated with removal of lymph nodes for cancer. Infection and prolonged time to healing were the main challenges. Negative pressure wound therapy was the most favoured treatment option. Negative pressure wound therapy was advocated by professionals despite a lack of research evidence indicating clinical or cost-effectiveness. Our findings underscore the need for rigorous evaluation of negative pressure wound therapy, and other wound care treatments, through studies that include economic evaluation. Clinical decision-making in wound care could be optimised through further robust studies to inform practitioners about the cost-effectiveness of available treatments.

Drosophila larval glue sticks to anything

Sticking to a surface is all part of the rite of passage from larva to adult for fruit flies (Drosophila melanogaster). After spitting out their sticky secretions, the larvae wriggle around to ensure that their salivary adhesive is smeared evenly between their body and the surface before it cures to form a secure bond. ‘The glue is composed of a small number of proteins called salivary gland secreted proteins’, says Virgine Courtier-Orgogozo, from the Institut Jacques Monod, France, who wants to identify the genes involved in glue adhesion to understand how the adhesive has evolved. However, before she could begin unravelling the details, Courtier-Orgogozo and her PhD student Flora Borne teamed up with insect attachment experts Alexander Kovalev and Stanislav Gorb from the University of Kiel, Germany, to find out how well the adhesive attaches to different surfaces.Using glass slides, which water spreads across with ease, slides treated to make them water-repellent and electrically chargeable epoxy resin surfaces, the team allowed 328 fruit fly larvae to settle on the different surfaces and secure themselves in preparation for pupation. Then, the scientists attached a force transducer to each pupa, before tugging on them to find out how tightly they had adhered, with only 56 detaching cleanly as the glue gave way. Calculating the force required to tear the pupae free, Courtier-Orgogozo was amazed that the adhesive could hold on with a force of ∼217 mN, 15,500 times the weight of a pupa. But she was most intrigued that the adhesive took hold successfully on all of the different surfaces, regardless of how water-repellent or chargeable they were.‘Amazing! How lucky to have such a universal glue at hand!’ exclaimed Courtier-Orgogozo, who is now eager to find out how well the adhesive adheres to more natural surfaces. And she is also keen to find out if she can learn how the adhesive gained its strength. ‘Our study paves the way for a genetic dissection of the components of D. melanogaster glue that confer its particular adhesive properties’, she says.

On the Origin of Changes in the Adhesive Interaction between Veneer and Glue under Glue Polarization in Plywood Manufacture

The possibilities of using an electrostatic field in the technology for manufacturing plywood by the example of birch veneer with the use of carbamide–formaldehyde epoxy or polyvinyl acetate glues have been considered. It has been shown that preliminary treatment of the glue in an electric field results in a decrease of the glue viscosity and leads to an increase in the plywood strength under chipping, whereas the polarization of plywood samples in the course of the gluing procedure causes the ultimate strength under chipping to increase. The results can be explained as being due to the orientation of the glue macromolecules owing to an electric field, which leads to hardening of the material. This effect may be caused by a double electric layer occurring at the veneer–glue interface, increasing the adhesion of the glue to the veneer, by lowering glue viscosity and improving veneer surface wettability, as well as by an increase in the free surface energy of glues in the course of polarization thereof.

Dopamine-Modified Hyaluronic Acid Hydrogel Adhesives with Fast-Forming and High Tissue Adhesion.

Commercial or clinical tissue adhesives are currently limited due to their weak bonding strength on wet biological tissue surface, low biological compatibility, and slow adhesion formation. Although catechol-modified hyaluronic acid (HA) adhesives are developed, they suffer from limitations: insufficient adhesiveness and overfast degradation, attributed to low substitution of catechol groups. In this study, we demonstrate a simple and efficient strategy to prepare mussel-inspired HA hydrogel adhesives with improved degree of substitution of catechol groups. Because of the significantly increased grafting ratio of catechol groups, dopamine-conjugated dialdehyde-HA (DAHA) hydrogels exhibit excellent tissue adhesion performance (i.e., adhesive strength of 90.0 ± 6.7 kPa), which are significantly higher than those found in dopamine-conjugated HA hydrogels (∼10 kPa), photo-cross-linkable HA hydrogels (∼13 kPa), or commercially available fibrin glues (2-40 kPa). At the same time, their maximum adhesion energy is 384.6 ± 26.0 J m-2, which also is 40-400-fold, 2-40-fold, and ∼8-fold higher than those of the mussel-based adhesive, cyanoacrylate, and fibrin glues, respectively. Moreover, the hydrogels can gel rapidly within 60 s and have a tunable degradation suitable for tissue regeneration. Together with their cytocompatibility and good cell adhesion, they are promising materials as new biological adhesives.

A Locomotion Mechanism for a Mobile Wall-Climbing Robot with a Hybrid Magnetic-Tape Adhesion Method

In the present study, a new hybrid passive adhesion method for a mobile wall-climbing robot (WCR) is proposed. This method is based on a combination of magnetic and glue adhesion. For its implementation, a flexible magnetic tape with glue on one side is used to fasten the tape to the working surface. Holding and climbing of the WCR on the magnetic tape, fixed by the robot in the process of movement, occurs with the help of the tracked locomotion mechanism. Permanent magnets are placed in the tracks of the WCR interacting with the tape as the robot climbs along a vertical surface. The concept of the adhesion and locomotion mechanisms, as well as the design of the WCR prototype is developed. Experimental studies of the magnetic properties of the proposed locomotion mechanism have been carried out. They showed its feasibility and efficiency. Also from experimental studies were obtained quantitative characteristics of the interaction of the WCR with tape, used in the construction of its mathematical model. A feature of this WCR concept, working on the magnetic-tape adhesion, is the possibility of moving it without using magnetic tape on ho rizontal surfaces, as well as on vertical ferromagnetic surfaces — only with tracks with permanent magnets. The WCR with a hybrid magnetic-tape adhesion mechanism is designed to move on various surfaces indoor spaces.

Control of defects in the multilayer dielectric materials and coatings in the microwave range

The development of modern engineering is inextricably linked with the development of the new types of multilayer dielectric materials. Existing radio wave methods for monitoring interlayer defects in such materials exhibit low accuracy in reconstructing the geometric parameters of defects. The results of studying extended interlayer defects in the three-layer coating consisting of polymethyl methacrylate, F-4D PTFE, and semi-hard rubber by the method of surface electromagnetic waves are presented. The method is based on the solution of inverse problems in the reconstruction of the geometric parameters of extended interlayer defects of special multilayer materials and coatings from the frequency dependence of the attenuation coefficient of the field of a slow surface electromagnetic wave. Unlike the methods that make use from the complex reflection coefficient we proposed to increase the accuracy of the reconstruction of the geometric parameters of extended interlayer defects taking into account the linear frequency dependence of the attenuation coefficient as well as reducing the number of fixed measurement frequencies. Moreover, the determination procedure is rather simple, since only the field strength of the surface electromagnetic wave is measured, and there is no need for phase measurements. Experimental data obtained on a multifrequency measuring complex in the range of 10 – 11 GHz were used for reconstruction of the interlayer defects in the coating under study. The developed method provided a relative error of thickness estimation below 10%. The proposed method approach can be used in studying multilayer dielectric coatings on the metal for detection of delamination in the lack of glue or poor adhesion between the layers. The developed method is also suitable for control of the defects in semiconductors, ferrite and composite materials.

The Analysis of Bending Stiffness and Strength of Glue Laminated Nigerian Timber

An analysis into the flexural strength of solid and laminated timber specimens under working conditions was conducted. Five hardwoods and five softwoods were investigated, namely: Mansonia, Mahogany, Orji, Ukpi, Ufi mmanu, White Afara, Owen, Melina, Akpu and Ubia. The dimensions of the wood specimens are 100mm×50mm×20mm. The wood samples were tested for flexural strength using a Universal Testing Tensile Machine. The results obtained shows that Owen has the highest ultimate wood strength of 46.806N/mm² for the softwood glulam. Ukpi has the highest wood strength of 73.375N/mm² for the hardwood glulam, and highest MOE at 2412.93N/mm². Akpu recorded the weakest sample with bending strength values for glulam at 11.929 N/mm². Comparisons of strength were made to their respective solid timbers. Failure modes were analyzed. The study therefore demonstrates that the timber species used can be engineered to load bearing glulam structural elements using polyurethane adhesive glue without severe loss of strength.

Analysis of Bending Stiffness and Strength of Glue Laminated Nigerian Timber

An analysis into the flexural strength of solid and laminated timber specimens under working conditions was conducted. Five hardwoods and five softwoods were investigated, namely: Mansonia, Mahogany, Orji, Ukpi, Ufi mmanu, White Afara, Owen, Melina, Akpu and Ubia. The dimensions of the wood specimens are 100mm×50mm×20mm. The wood samples were tested for flexural strength using a Universal Testing Tensile Machine. The results obtained shows that Owen has the highest ultimate wood strength of 46.806N/mm² for the softwood glulam. Ukpi has the highest wood strength of 73.375N/mm² for the hardwood glulam, and highest MOE at 2412.93N/mm². Akpu recorded the weakest sample with bending strength values for glulam at 11.929 N/mm². Comparisons of strength were made to their respective solid timbers. Failure modes were analyzed. The study therefore demonstrates that the timber species used can be engineered to load bearing glulam structural elements using polyurethane adhesive glue without severe loss of strength.

Mortise and tenon–type elastic adhesive bandage for noninvasive closure of oozing wounds at areas of tension

Various wound closure techniques such as suturing, staples, tissue glue, or adhesive tapes are available. Adhesive surgical tape strips (Steri-Strips, 3M, St. Paul, MN) and tissue glue are not feasible for wounds with tension or oozing (Fig 1, A).1 Suturing and staples are invasive methods that demand additional cost and sometimes may leave cross-hatching marks.1

A Novel Double‐Crosslinking‐Double‐Network Design for Injectable Hydrogels with Enhanced Tissue Adhesion and Antibacterial Capability for Wound Treatment

AbstractMost photocrosslinkable hydrogels have inadequacy in either mechanical performance or biodegradability. This issue is addressed by adopting a novel hydrogel design by introducing two different chitosan chains (catechol‐modified methacryloyl chitosan, CMC; methacryloyl chitosan, MC) via the simultaneous crosslinking of carbon–carbon double bonds and catechol‐Fe3+ chelation. This leads to an interpenetrating network of two chitosan chains with high crosslinking‐network density, which enhances mechanical performance including high compressive modulus and high ductility. The chitosan polymers not only endow the hydrogels with good biodegradability and biocompatibility, they also offer intrinsic antibacterial capability. The quinone groups formed by Fe3+ oxidation and protonated amino groups of chitosan polymer further enhance antibacterial property of the hydrogels. Serving as one of the two types of crosslinking mechanisms, the catechol‐Fe3+ chelation can covalently link with amino, thiol, and imidazole groups, which substantially enhance the hydrogel's adhesion to biological tissues. The hydrogel's adhesion to porcine skin shows a lap shear strength of 18.1 kPa, which is 6‐time that of the clinically established Fibrin Glue's adhesion. The hydrogel also has a good hemostatic performance due to the superior tissue adhesion as demonstrated with a hemorrhaging liver model. Furthermore, the hydrogel can remarkably promote healing of bacteria‐infected wound.

Tough and translucent hydrogel electrode for electrochemical cleaning of paper artworks

Due to the favorable retention power and viscosity, the hydrogel that is loaded with an aqueous detergent, represents a promising cleaning tool for removing the foreign matters such as polymer adhesive, starch paste, and animal glue from paper artworks. However, it is still challenging to eliminate other stains, including organic dyes, commercial drinks, foxing, and mildew. Herein, we present an alternative methodology, translucent hydrogel-containing electrolyte-based electrochemical cleaning (EC), which incorporates electrochemical reactions into the hydrogel-based cleaning process using the extremely tough and translucent alginate/polyacrylamide hydrogel as cathode and PbO2 as anode. The proposed approach is generally applicable to eliminate different stains such as organic dyes, commercial drinks, mildew, and foxing from paper under several mA/cm2 and a few minutes in a small controlled area. For the excellent mechanical strength, the hydrogel electrode can be reused for several times without losing its efficiency and easily peeled-off from paper as one body without any gel residues after cleaning. We further demonstrate the effect of EC on the treated paper, including the morphology, degree of polymerization, crystal structure, and mechanical properties. We conclude that the influence of EC on the paper is slight under the mild treatment.

Analysis of Different Stripe Connectors for a Gabion Wall based on Woven Waste Tire Stripes

In this research, woven waste tire stripes are proposed as an alternative material to wire mesh to make a gabion wall. The performance of the waste tire stripe-based gabion wall is highly dependent on the strength of its stripe, where the stripe connector plays an important role. This research aims to inspect the behavior of different stripe connectors for the gabion wall. To achieve this, a physical model was built and employed to test the strength of the gabion wall. Various stripe connectors are used; adhesive rubber glue, one inch nail, and two mm wire. The strength capacity of the models was determined from the maximum stress before failure. The strength capacities of the models are 83.197, 59.426 and 62.397 kPa for the wire, nail, and glue connector, respectively. Hence, it can be inferred that the wire connector is the strongest of the three connectors.

ARTISS (Fibrin Sealant Spray): Day-case Drain-less Mastectomy

Background: The use of drains in breast surgery is decreasing, and various methods of reducing the dead space after mastectomy in breast cancer have been described such as the quilting of skin flaps and the use of adhesive tissue glues. The British Association of Day Surgery (BADS) outlines a 30% day-case target for simple mastectomy procedures. We conducted a feasibility study using a fibrin sealant spray (ARTISS) instead of drains in mastectomy without reconstruction and prospectively audited the concomitant length of stay (LOS) & post-operative complications.

Study on Physico-Mechanical Properties of the Modified Alkaline Aluminosilicate Adhesive-Bonded Timber Elements

The purpose of the work was to study physico-mechanical properties of glued connections of wood rods, toothed lamellae after splicing and corner spike clamping of window frames which were obtained in the production conditions. The alkaline aluminosilicate binder-based adhesive (glue) of the composition 0.8Na2O·Al2O3·4.5SiO2·20H2O modified using organo-mineral additives was used in testing. After solidification of the adhesive, the samples were cut to determine the strength of frame corner joints in bending, glued timber connections for splitting along the grains, toothed glued connections in bending and water resistance of the glued connections of timber elements. The results of these tests showed high values of strength characteristics in case of the proposed modified alkaline aluminosilicate binder-based adhesive (glue), which were by 1.5 times higher than those in case of the WoodMax (D2) taken as a reference glue, and in water resistance complied with Class D2/D3 as per PN-EN 204.

Soil lacquer peel do-it-yourself: simply capturing beauty

Abstract. Visualization can greatly benefit understanding of concepts and processes, which in soil science and geology can be done using real-life snapshots of soils and sediments in lacquer peels and glue peels. While it may seem complicated, anyone can make such a soil peel for use in classrooms, public places, homes, and offices for teaching, outreach, decoration, and awareness. Technological development has considerably simplified the making of soil peels, but this methodological innovation has not been described in the literature. Here, we report on a thoroughly tested and simple method for taking peels of sandy soils using readily available tools and materials. Our method follows the main previously published steps of preparing a soil face, impregnating the soil face with a fixation agent in the field, extracting the resulting peel, and mounting it on a wooden panel. Yet instead of using lacquers and thinning agents, we use strong though flexible contact adhesive (glue), which has the major advantage that it no longer requires use and mixing of toxic chemicals in the field or reinforcement of the peel to prevent breaking. Moreover, the preservation potential is much higher than with the old method. This new twist to old methods makes creation of soil peels safer, simpler, and more successful, and thereby a true DIY (do-it-yourself) activity. The resulting increased accessibility of making soil and sediment peels can benefit research, teaching, and science communication and can thereby bring the value and beauty of the ground below our feet to students, schools, policy makers, and the general public.

Semi-Field Evaluation of Modified 00ZZZero® Traps with Sticky Paper to Increase the Collection Efficacy of Gravid Aedes aegypti.

The 00ZZZero® trap (0Z) is a small black plastic container with permethrin and pyriproxyfen, designed and marketed to both attract and kill gravid Aedes mosquitoes (unmodified trap ([UMT] or modified trap [MT]). The 0Z trap without the insecticide was modified with addition of a sticky paper, coated with an adhesive glue (MT) and evaluated for collection efficacy of released gravid mosquito, Aedes aegypti (L.) in outdoor screened enclosures in St. Augustine, in northeastern Florida. The mean numbers (±SE) of mosquitoes caught by MTs were 130.67 ± 23.95 (40.22 ± 5.78 mosquito/trap), compared with 2.33 ± 0.88 (0.79 ± 0.29 mosquito/trap) mosquitoes caught by UMTs. The MTs collected significantly more mosquitoes, 44.16% (F = 4.495, P < 0.05) of the released mosquitoes, than those captured in UMTs (0.83%). The number of immature mosquitoes (larvae and pupae) hatched from eggs laid in the MTs and UMTs were 79.3 ± 23.1 and 19.3 ± 6.8, respectively. The mean numbers (±SE) of adults emerging in MTs and UMTs were 34.0 ± 22.3 and 14.0 ± 6.8, respectively. These results show the potential of the sticky paper modified 0Z traps to be used both to increase the efficacy of collection and as a sticky autocidal tool against gravid Ae. aegypti.

Reducing seroma formation and its sequelae after mastectomy by closure of the dead space: The interim analysis of a multi-center, double-blind randomized controlled trial (SAM trial)

ObjectiveThe main objective of this double-blind randomized controlled trial (RCT) was to assess seroma formation and its sequelae in patients undergoing mastectomy. Patients were randomized into one of three groups in which different wound closure techniques were applied: 1) conventional wound closure without flap fixation (CON) 2) flap fixation using sutures (FF–S) and 3) flap fixation using an adhesive tissue glue (FF-G). BackgroundSeroma formation is still a bothersome complication after mastectomy. Flap fixation seems promising in reducing seroma formation. Various flap fixation techniques remain to be analyzed, including long-term outcome measures. MethodsThis trial was conducted in three different hospitals between June 2014 and November 2016. Patients were allocated to one of three groups. The primary outcome was the number of seroma needle aspirations. Secondary outcomes were (surgical site) infections, number of outpatient clinic visits, shoulder function, postoperative pain, patient-reported cosmesis and skin dimpling. ResultsA total of 187 patients were randomly assigned to CON (n = 61), FF-S (n = 64) and FF-G (n = 62). The number of seroma aspirations was significantly higher in CON when compared to both flap fixation groups (p = 0.032), with no difference between FF-S and FF-G. Secondary outcomes showed no statistical differences between all groups. The higher number of outpatient clinic visits in CON was considered to be of clinical importance (CON = 27 (44.3%), FF-S = 19 (30.6%) and FF-G = 21 (34.4%)). ConclusionsMastectomy followed by flap fixation with either sutures or adhesive tissue glue reduces the number of seroma aspirations when compared to simple wound closure.