Additional Questionnaire Research Articles

Cohort profile: The Swedish Tattoo and Body Modifications Cohort (TABOO)

PurposeThe Swedish Tattoo and Body Modifications Cohort (TABOO) cohort was established to provide an infrastructure for epidemiological studies researching the role of tattoos and other body modifications as risk factors...

Features of Cognitive Ability and Central Auditory Processing of Preschool Children With Minimal and Mild Hearing Loss.

This study aimed to investigate the current status of cognitive development and central auditory processing development of preschool children with minimal and mild hearing loss (MMHL) in Nanjing, China. We recruited 34 children with MMHL and 45 children with normal hearing (NH). They completed a series of tests, including cognitive tests (i.e., Wechsler Preschool and Primary Scale of Intelligence and Continuous Performance Test), behavioral auditory tests (speech-in-noise [SIN] test and frequency pattern test), and objective electrophysiological audiometry (speech-evoked auditory brainstem response and cortical auditory evoked potential). In addition, teacher evaluations and demographic information and questionnaires completed by parents were collected. Regarding cognitive ability, statistical differences in the verbal comprehensive index, full-scale intelligence quotient, and abnormal rate of attention test score were found between the MMHL group and the NH group. The children with MMHL performed poorer on the SIN test than the children with NH. As for the auditory electrophysiology of the two groups, the latency and amplitude of some waves of the speech-evoked auditory brainstem response and cortical auditory evoked potential were statistically different between the two groups. We attempted to explore the relationship between some key indicators of auditory processing and some key indicators of cognitive development. Children with MMHL are already at increased developmental risk as early as preschool. They are more likely to have problems with attention and verbal comprehension than children with NH. This condition is not compensated with increasing age during the preschool years. The results suggest a possible relationship between the risk of cognitive deficit and divergence of auditory processing. https://doi.org/10.23641/asha.22670473.

Prevalence, factors associated and knowledge of probable dementia among adults 50 years and over attending a faith-based geriatric center in Uganda

Dementia is on the rise due to increasing proportion of old people in sub-Saharan Africa (SSA). Although dementia is misattributed to normal ageing or supernatural causes in SSA, it is a brain disease with well-established etiologies. Limited knowledge and understanding of dementia means that many older people are suffering without seeking help and are undiagnosed and untreated. The aim of this study was to determine the prevalence and factors associated with probable dementia and to describe the knowledge of the disease among adults 50 years and over attending a faith-based geriatric center in Uganda. This was a cross-sectional study using quantitative methods. A total of 267 adults 50 years and over attending a faith-based geriatric center in Mukono, Uganda were interviewed between 1 April and 15 May 2022. Interviews were administered using the Early Dementia Questionnaire (EDQ) and Dementia Knowledge Assessment Scale (DKAS). Data on participants’ socio-demographics, economic income, living arrangement, history of smoking, alcohol consumption, exercise and past medical history was collected using an additional questionnaire. Adults 50 years and over were included in the study. Logistic regression analyses were done. Probable dementia was 46.2% in the sample. The most common symptoms of probable dementia in the order of their severity were memory symptoms, (β co-efficient β 0.08, p < .001), physical symptoms (β 0.08, p < .001), sleep disturbances (β 0.81, p < .001) and emotions (β 0.04, p < .027). The final degree of association as determined by adjusted PR in the multivariable model revealed that only older age (aPR = 1.88, p < .001) and occasional/non-believer (aPR = 1.61, p = .001) remained significantly related to probable dementia. The study also found that 8.0% of the participants had optimal knowledge of dementia. There is high burden of probable dementia among adults 50 years and over attending a faith-based geriatric center in Mukono, Uganda. Factors associated with probable dementia are older age and being an occasional/non-believer. Knowledge of dementia among older adults is low. There is need to promote integrated early dementia screening, care and educational program in primary care to reduce the disease burden. Spiritual support would be a rewarding investment in the lives of the ageing population.

Evaluation of a Structured Screening Assessment to Detect Isolated Rapid Eye Movement Sleep Behavior Disorder.

Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) cohorts have provided insights into the earliest neurodegenerative processes in α-synucleinopathies. Even though polysomnography (PSG) remains the gold standard for diagnosis, an accurate questionnaire-based algorithm to identify eligible subjects could facilitate efficient recruitment in research. This study aimed to optimize the identification of subjects with iRBD from the general population. Between June 2020 and July 2021, we placed newspaper advertisements, including the single-question screen for RBD (RBD1Q). Participants' evaluations included a structured telephone screening consisting of the RBD screening questionnaire (RBDSQ) and additional sleep-related questionnaires. We examined anamnestic information predicting PSG-proven iRBD using logistic regressions and receiver operating characteristic curves. Five hundred forty-three participants answered the advertisements, and 185 subjects fulfilling inclusion and exclusion criteria were screened. Of these, 124 received PSG after expert selection, and 78 (62.9%) were diagnosed with iRBD. Selected items of the RBDSQ, the Pittsburgh Sleep Quality Index, the STOP-Bang questionnaire, and age predicted iRBD with high accuracy in a multiple logistic regression model (area under the curve >80%). When comparing the algorithm to the sleep expert decision, 77 instead of 124 polysomnographies (62.1%) would have been carried out, and 63 (80.8%) iRBD patients would have been identified; 32 of 46 (69.6%) unnecessary PSG examinations could have been avoided. Our proposed algorithm displayed high diagnostic accuracy for PSG-proven iRBD cost-effectively and may be a convenient tool for research and clinical settings. External validation sets are warranted to prove reliability. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Forecasting levels of serum 25-hydroxyvitamin D based on dietary intake, lifestyle and personal determinants in a sample of Southern Europeans.

Vitamin D is an essential nutrient to be consumed in the habitual dietary intake, whose deficiency is associated with various disturbances. This study represents a validation of vitamin D status estimation using a semi-quantitative FFQ, together with data from additional physical activity and lifestyle questionnaires. This information was combined to forecast the serum vitamin D status. Different statistical methods were applied to estimate the vitamin D status using predictors based on diet and lifestyle. Serum vitamin D was predicted using linear regression (with leave-one-out cross-validation) and random forest models. Intraclass correlation coefficients, Lin's agreement coefficients, Bland-Altman plots and other methods were used to assess the accuracy of the predicted v. observed serum values. Data were collected in Spain. A total of 220 healthy volunteers aged between 18 and 78 years were included in this study. They completed validated questionnaires and agreed to provide blood samples to measure serum 25-hydroxyvitamin D (25(OH)D) levels. The common final predictors in both models were age, sex, sunlight exposure, vitamin D dietary intake (as assessed by the FFQ), BMI, time spent walking, physical activity and skin reaction after sun exposure. The intraclass correlation coefficient for the prediction was 0·60 (95 % CI: 0·52, 0·67; P < 0·001) using the random forest model. The magnitude of the correlation was moderate, which means that our estimation could be useful in future epidemiological studies to establish a link between the predicted 25(OH)D values and the occurrence of several clinical outcomes in larger cohorts.

Prise en charge de la gangrène des organes génitaux externes et du périnée : résultats, qualité de vie et évaluation fonctionnelle

External genitalia gangrene is a well-known uncommon disease; however, mortality remains important. Recent literature focuses on early management. The object of this study was to assess quality of life and disease-specific function, in the medium- and long-term. We evaluated retrospectively adult inpatients with external genitalia gangrene who had a surgical debridement between 2010 and 2020 at CHU de Poitiers. Preoperatory FGSI Score was calculated for patients included. In a second phase, surviving patients at 2020 who had agreed to take part in the follow-up were assessed by clinical examination, and asked to complete Short-Form 36 test and two additional disease-specific questionnaire (USP, IIEF5). The patients consisted of 33 men. Mean age was 61.18. Eleven patients (33%) died primarily from external genitalia gangrene. Median FGSI score was 6 (1-13). We were able to reach 11 patients (33%) for secondary clinical revaluation. Time before revaluation was 3months to 8years. All parts of SF-36 were significantly low. Mean USP score was 1.27±2.68/4.54±4.43/0.72±1.84. Nine patients (81%) suffered erectile dysfunction without any sexual intercourse possible. Patients with external genitalia gangrene experience severe deterioration of their quality of life. Multidisciplinary healthcare process should systematically be carried out, as so as early screening of vulnerability risks factors, to improve functional outcomes and quality of life.

Prognostic factors for the development of lower respiratory tract infection after influenza virus infection in allogeneic hematopoietic stem cell transplantation recipients: A Kanto Study Group for Cell Therapy multicenter analysis

ObjectivesInfluenza virus infection (IVI) occasionally causes lower respiratory tract infection (LRTI) in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. Although the progression to LRTI entails a high mortality, the role of early antiviral therapy for its prevention has not been fully elucidated. MethodsThis was a multicenter retrospective study using an additional questionnaire. Allo-HSCT recipients who developed IVI between 2012 and 2020 were included. ResultsA total of 278 cases of IVI after allo-HSCT were identified from 15 institutions. The median patient age was 49 years, and the median time from allo-HSCT to IVI was 918 days. Neuraminidase inhibitors were administered within 48 hours of symptom onset (early neuraminidase inhibitor [NAI]) in 199 (76.9%) patients. Subsequently, 36 (12.3%) patients developed LRTI. On the multivariate analysis, age ≥50 years (hazard ratio [HR], 2.16; 95% confidence interval [CI], 1.02-4.58) and moderate to severe chronic graft-versus-host disease (HR, 2.28; 95% CI, 1.14-4.58) were significantly associated with progression to LRTI, whereas early NAI suppressed the progression (HR, 0.17; 95% CI, 0.06-0.46). The IVI-related mortality rate was 2.2%. ConclusionTo reduce the risk of LRTI development after IVI, early NAI therapy should be considered in allo-HSCT recipients, especially with older patients and those with chronic graft-versus-host disease.

Late outcome of coronary artery bypass grafting with or without mitral repair for moderate or moderate-severe ischemic mitral regurgitation.

Operative indication of the additional mitral repair for moderate ischemic mitral regurgitation (MR) in the setting of coronary artery bypass grafting (CABG) is still unclear. This study was designed as the nation-wide multi-center retrospective analysis with additional survival data. CABGs without past heart surgery registered in 2014 and 2015 were included. Concomitant surgery other than tricuspid or arrhythmia surgery, mitral replacement, and off-pump cases, was excluded. Grade 1 or 4 MR, and ejection fraction < 20 or > 50 were excluded. Additional questionnaire was sent to each hospital, regarding the pathology of MR and clinical outcomes. Additional data were registered between May 28, 2021 and Dec 31, 2021, and the primary outcomes were all-death and cardiac death. The secondary outcomes were heart failure and cerebrovascular event requiring admission, mitral re-intervention. Patients underwent on-pump CABG (CABG only group 221 cases) and CABG with mitral repair (CABG + Mitral repair group 276 cases) were enrolled. After Propensity score matching, 362 cases (CABG only 181cases vs CABG + mitral repair 181 cases) were matched. Cox regression model showed no statistical difference in the long-term survival between CABG alone group and combined procedure group (p = 0.52). Cardiac death (p = 1.00), heart failure (p = 0.68), and cerebrovascular event (p -0.80) requiring admission were not different between groups as well. The incidence of mitral re-intervention was very few (2 cases in CABG only group, 4 cases in CABG + mitral repair group). In patients with moderate ischemic MR, additional mitral repair to CABG did not improve long-term survival, freedom from heart failure, or cerebrovascular event.

Comparison of leadless pacemaker and conventional pacemaker for quality of life improvement in patients with bradyarrhythmias

Objective: To compare the improvement in quality of life (QoL) after implantation of leadless pacemakers (L-PM) with that of conventional pacemakers (C-PM) in patients with slow-onset arrhythmias. Methods: A total of 112 patients who received pacemaker implantation for the first time at Beijing Anzhen Hospital from January 2020 to July 2021 were selected, including 50 leadless pacemakers (L-PM) and 62 conventional pacemakers (C-PM). Clinical baseline data were collected, pacemaker-related complications and SF-36 scores were recorded and followed up at 1, 3, and 12 months post-operatively; SF-36 questionnaires and additional questionnaires were completed to compare the quality of life of the 2 groups; and factors associated with the change in QoL from baseline to 1, 3 and 12 months post-operatively were analyzed using multiple linear regression models. Results: The age of the 112 patients was (70.3±10.5) years, and 69 patients (61.6%) were male. The age of patients with L-PM and C-PM was (75.8±8.5) years and (67.5±10.4) years, respectively (P=0.004). In the L-PM group, 50 patients completed 1-, 3-, and 12-month follow-up. In the C-PM group, 62 patients completed the 1-month and 3-month follow-up, and 60 completed the 12-month follow-up. The C-PM group had a higher incidence of discomfort in the surgical area, impact of daily activities for the discomfort in the surgical area, and concern about heart or overall condition than the L-PM group on the additional questionnaire (all P values<0.05). After adjusting for age and SF-36 scores at baseline, at 12th month of follow-up, patients implanted with C-PM had lower values for quality of life PF, RP, SF, RE, and MH scores compared to patients implanted with L-PM, with beta values (95%CI) of -24.500 (-30.010--18.981), -27.118 (-32.997--21.239), -8.085 (-12.536--3.633), -4.839 (-9.437--0.241), -12.430 (-18.558--6.301), respectively (all P values<0.05). Conclusions: L-PM is associated with better QoL in slow arrhythmias patients, and patients who received L-PM reported less activity limitations due to surgical discomfort and less emotional distress.

A Multifactorial Examination Of Stock Market Attitudes Of Investors

This study investigates the pivotal role of economic conditions in influencing investment decision-making across various avenues, such as stocks, bonds, and real estate. The primary objective is to identify significant predictors affecting investment decisions, particularly concerning awareness about the stock market. The research employs a survey methodology, targeting a sample of 380 active investors from the Visakhapatnam district. Data collection involves a self-developed questionnaire featuring 30 items comprehensively covering General, Company, Political and Economic, Financial, Marketing, and psychological factors. An additional questionnaire focusing on awareness incorporates 20 items rated on a Likert scale with three points.&#x0D; The collected data undergoes rigorous regression analysis to identify and analyze significant predictors influencing investment decisions. The results reveal that General Factors, Company Factors, Political and Economic Factors, Financial Factors, and Marketing Factors significantly predict stock market awareness. Notably, psychological factors play a comparatively less prominent role in this context. These findings provide valuable insights for enhancing understanding and education regarding stock market dynamics. The study contributes to the ongoing discourse on financial literacy and investor awareness, offering practical implications for stakeholders, policymakers, and educators in investment decision- making.

Prevalence of focal odontogenic infection in patients with class II malocclusion studying at Russian Ministry of Defense institutions of comprehensive education

Relevance. Caries and premature loss of teeth is among the causes of the development of malocclusion. Caries develops with greater frequency on proximal and occlusal surfaces of mandibular first molars, which increases the risk of periapical complications due to late diagnosis of tooth decay. Students of the Russian Ministry of Defense schools for comprehensive education belong to reserve units of law enforcement authorities, agencies and services. Therefore, prevention and sustaining their good health, including dental health, is a top priority.The paperobjectiveis to evaluate the frequency of carious lesions of various surfaces of mandibular molars and their complications in students of educational institutions of the Ministry of Defense of Russia.Methods. We examined 30 first year students with class II malocclusion (K07.20 according to ICD-10) aged 11-12 years, using basic (clinical examination and probing) and additional (questionnaires, photo protocol, radiography) research methods. All patients underwent cone beam computed tomography (CBCT) in natural occlusion with a resolution of 17Ч15.Results and discussion. 45 % of the examined students revealed latent carious lesions of the enamel below the level of the equator, predominantly localized on the tooth medial surface. At the same time, carious lesions communicating with the tooth cavity in 60.9 % of cases were localized on the contact surfaces (Class II according to Black), in 39.1% - on the chewing surface (Class I according to Black). Periapical foci of destruction were found in 38.3 % of cases.Conclusion. When diagnosing and planning orthodontic treatment of malocclusion in students of the Russian Ministry of Defense institutions, it is important to refer the patient to CBCT in order to timely detect hidden carious lesions of the enamel below the equator and prevent the transition of uncomplicated caries into complicated cases.

Opioid use following pelvic reconstructive surgery: a predictive calculator.

Our objective was to evaluate the amount of opioids used by patients undergoing surgery for pelvic floor disorders and identify risk factors for opioid consumption greater than the median. This was a prospective cohort study of 18- to 89-year-old women undergoing major urogynecological surgery between 1 November2020 and 15 October 2021. Subjects completed one preoperative questionnaire ("questionnaire 1") that surveyed factors expected to influence postoperative pain and opioid use. At approximately 1 and 2 weeks following surgery, patients completed two additional questionnaires ("questionnaire 2" and "questionnaire 3") about their pain scores and opioid use. Risk factors for opioid use greater than the median were assessed. Finally, a calculator was created to predict the amount of opioid used at 1 week following surgery. One hundred and ninety patients were included. The median amount of milligram morphine equivalents prescribed was 100 (IQR 100-120), whereas the median amount used by questionnaire 2 was 15 (IQR 0-50) and by questionnaire 3 was 20 (IQR 0-75). On multivariate logistic regression, longer operative time (aOR 1.64 per hour of operative time, 95% CI 1.07-2.58) was associated with using greater than the median opioid consumption at the time of questionnaire 2; whereas for questionnaire 3, a diagnosis of fibromyalgia (aOR=16.9, 95% CI 2.24-362.9) was associated. A preliminary calculator was created using the information collected through questionnaires and chart review. Patients undergoing surgery for pelvic floor disorders use far fewer opioids than they are prescribed.

ANALISIS DAMPAK BEBAN KERJA DAN GAJI TERHADAP KINERJA KARYAWAN TENAGA SUKARELA RUMAH SAKIT : PERSPEKTIF POTENSI KECURANGAN YANG TERJADI

As an effort to realize the vision and mission of the Hospital, employee performance must increase. In the process of improving employee performance, it must pay attention to factors that can improve performance. However, this work should not be done haphazardly and must still be in accordance with the Hospital SOP. This study aims to determine the effect of workload and salary on the performance of volunteer employees, as well as to see the potential for fraud that may occur during the process of completing work.The population in this study were all temporary staff including nurses and nutritionists who worked at one of the hospitals in Semarang, with a total sample of 76 respondents. The data source used is primary data using a questionnaire. The data analysis technique used is multiple linear regression.The results showed that the workload variable has a negative effect on employee performance. Furthermore, salary has a positive effect on employee performance. Additional questionnaires show that high workloads and salaries that are not in line with expectations but performance demands remain high, will have the potential to cause activities that are not in accordance with the provisions and SOPs of the Hospital

Critical care echocardiography: barriers, competencies and solutions. A survey of over 600 participants.

Critical care echocardiography (CCE) is at the core of point-of-care ultrasound (POCUS), and although a list of the necessary competencies has been created, most European countries do not have established training programmes to allow intensivists to gain such competencies. To address barriers to the implementation of CCE, we conducted an online European survey, and analysed the current barriers to this with the aim of providing novel, modern solutions to them including environmental considerations. A 23-item survey was distributed via email with support from the European Society of Intensive Care Medicine, national societies, and social media. Questions focused on bedside CCE prevalence, competencies, and barriers to its implementation. An additional questionnaire was sent to recognised experts in the field of CCE. A total of 644 responses were recorded. Most respondents were anaesthesia and intensive care physicians [79% ( n = 468)], and younger, with 56% in their first five years after specialization ( n = 358). Most respondents [92% ( n = 594)] had access to an ultrasound machine with a cardiac probe, and 97% ( n = 623) reported being able to acquire basic CCE windows. The most common barriers identified by respondents to the implementation of CCE in practice were a lack of sufficient experience/skill [64% ( n = 343)], absence of formal qualifications [46% ( n = 246)] and lack of a mentor [45% ( n = 243)]. Twenty-eight experts responded and identified a lack of allocated time for teaching as a main barrier [60% ( n = 17)]. We found that bedside CCE is perceived as a crucial skill for intensive care medicine, especially by younger physicians; however, there remain several obstacles to training and implementation. The most important impediments reported by respondents were inadequate training, absence of formal qualifications and difficulties in finding a suitable mentor.

Determinants of Russian Attitudes Toward a Green Economy During the Covid-19 Pandemic

Background. The development of environmental consciousness is a necessary part of the full development of society. The pandemic caused by COVID-19 has increased attention to the problems of man’s relationship with nature, and the green behavior of both the consumer and the producer. Attitudes toward a green economy are especially important to study in countries rich in natural resources, as they have more opportunities to overcome the contradictions between economic growth and green innovation. Objective. The purpose of this study was to identify the determinants of Russian attitudes toward a green economy during the COVID-19 pandemic. The main hypothesis was that demographic factors determine attitudes toward a green economy in different ways, including the willingness to take actions in support of it, and acknowledgement of the connection of the need for green transformations with the pandemic. Design. Subjects were given the questionnaire “Green Economy” which contains 19 statements with which they needed to express their degree of agreement on a 5-point Likert scale. Potential determinants of their attitudes toward a green economy were collected using an additional questionnaire, which included indicators of gender, age, family and professional status, religiosity, income level, education level, and place of residence (locality). The study involved 874 respondents from the Russian Federation (62.4% female; 37.6% male; the average age was 37.34 years). Results. The results of a regression analysis showed that women, people with increased religiosity (but not too religious), younger people, and students and employees of public organizations (as opposed to employees of state and commercial organizations), as well as people from small towns or rural areas, were more positive about the idea of transition to a green economy. Conclusion.The belief that the pandemic situation has reinforced the need for a transition to a green economy was influenced by gender, degree of religiosity, and place of residence. Women, to a greater extent than men, as well as people who were more religious and lived in small towns and rural areas, were more acutely aware of the impact of the pandemic on the actualization of environmental problems.

Epidemiological Aspects and Factors Associated with Early Neonatal Death From 2018 to 2020 in the Maternity of the Savè-Ouessè Health Zone, Benin, West Africa

Background: Most of the new-born deaths occur in developing countries where care access is poor. This study aimed to investigate the epidemiological aspects and factors associated with early neonatal death in maternity. Subjects and Method: A case-control study was conducted from 2018 to 2020 in the Savè-Ouessè (SaO) health zone in the Collines department in Benin. Two groups of new-borns aged 0-7 days were recruited, 176 cases and 176 controls. The dependent variable was early neonatal death. The main independent variables studied were related socio-demographic characteristics, medical and gynaeco-obstetric history, pregnancy-related illnesses, service use and quality of health care, and neonatal parameters. Data collection was carried out from October to December 2021 from delivery records at the maternity unit level. An additional questionnaire was addressed to corresponding mothers. Logistic regression model was used to identify factors that explain early neonatal death occurrence. Results: No Fertility desire (OR= 3.22; CI95%= 1.13 to 9.16; p =0.029); No Observance of ANC rhythms (OR= 5.14; CI95%= 1.63 to 16.15; p= 0.005); Supervised intake of SP (OR= 6.33; CI95%= 1.33 to 29.99; p&lt;0.001); No Existence of active fetal movements (OR= 7.01; CI95%= 2.67 to 18.41; p&lt;0.001); and Amniotic fluid colour/ Haematic (OR= 4.09; CI95%= 2.07 to 9.63; p&lt;0.001) increased early neonatal death in SaO health zone from 2018 to 2020 in SaO health zone, Benin Conclusion: Even if early neonatal mortality appears to be low in the SaO health zone, its reduction requires to strengthen family planning, to improve the observance of intermittent preventive treatment and to monitor obstetric labour. Keywords: perinatal death, early neonatal, death, associated factors, Benin. Correspondence: Damien Barikissou Georgia. Population Training and Research, University of Abomey-Calavi, Benin. Email: barikiss2000@yahoo.fr. Journal of Maternal and Child Health (2023), 08(01): 91-104 https://doi.org/10.26911/thejmch.2023.08.01.09

Anthropometry and physical appearance can be associated with quality of life in Brazilian women with Turner syndrome.

This study aimed to analyze if anthropometric factors and physical appearance are associated to QoL in Turner syndrome (TS). Observational, analytical, and cross-sectional study. The SF-36 was applied along with an additional questionnaire regarding specific characteristics of TS. There were no differences in quality of life (QoL) in TS women regarding median height and appropriate height according to parental target height, however, participants satisfied and who did not desire to change their height had better scores in the mental health and role emotional domains than those not satisfied and desired to change it. When comparing participants who were or were not bothered by physical appearance, the results showed that those not bothered by physical appearance had a better score in the vitality and social function domains. Considering patients who did or did not desire to change physical appearance, those who did not want to change their physical appearance had higher scores in the mental component and in the social function and mental health domains of the SF-36. This study indicated that anthropometric factors and physical appearance may possibly be associated to QoL in TS, and also emphasizes the need to develop and validate an official questionnaire regarding specific TS characteristics in order to assess in more detail how specific characteristics of TS interfere with their QoL.

S1 Sarcopenia Is Associated With Social Determinants of Health in Patients With Inflammatory Bowel Disease

Background: Sarcopenia is defined as the loss of skeletal muscle mass and is a modifiable condition that affects between 27% to 61% of patients with inflammatory bowel disease (IBD). Social determinants of health (SDOH) are increasingly being identified as contributors to disparities and health outcomes in IBD. However, the impact of SDOH on sarcopenia in IBD remains understudied. We aimed to perform a comprehensive evaluation of the presence of SODH in sarcopenia within an IBD patient population. Methods: Patients (≥18 years) seen at the IBD Center with a confirmed diagnosis of IBD without short bowel syndrome were invited to complete a SARC-F questionnaire to assess for sarcopenia. Sarcopenia on SARC-F was defined as a score ≥4. Patients completed an additional 11-item dichotomous SDOH questionnaire. Retrospective chart review was performed for demographic and disease characteristics for all patients that completed the questionnaires. Each item on the SODH questionnaire was considered a risk factor and compared between the sarcopenia and non-sarcopenia groups using univariable analysis. The false discovery rate was used in multiple hypothesis testing to correct for multiple comparisons (shown as the q-value). Results: Among 233 patients that completed the SARC-F questionnaire, 44 patients met criteria for sarcopenia with a score ≥4 on SARC-F. Patients with sarcopenia had an average age of 48 and were predominantly Caucasian (95%). Tobacco use (25% vs 3.7%, P < 0.001), history of bowel surgery (59% vs 33%, P < 0.001) and body mass index (30 vs 26, P < 0.001) were all associated with sarcopenia on SARC-F. Almost all patients (99%) identified at least 1 SDOH factor, with an average of 3.9 factors. The most common SDOH factors in patients with sarcopenia were limited meetings or interactions with support groups (88%) and religious groups (79%). On univariable analysis, difficulty paying for basic needs such as food, housing, transportation, and medications (51% vs 15%, P < 0.001) was associated with sarcopenia. Patients that identified themselves as a lot or very stressed (60% vs 33%, P < 0.001) or had limited interactions with friends/relatives (47% vs 27%, P = 0.013) were also more likely to have sarcopenia. After applying the false discovery rate, these factors remained significant based on q-value. Conclusion(s): Our study identifies a high burden of social barriers amongst IBD patients with sarcopenia and SDOH screening should be considered at the time of diagnosis. Difficulty with basic needs, stress and limited interactions with loved ones are prevalent SDOH associated with sarcopenia in IBD. Multi-disciplinary interventions with social workers and mental health specialists may help address these needs.

The self-management and transition manual “ALL YOU NEED IS LOVE” for adolescents with chronic kidney disease

PurposeTo examine the effects of “ALL YOU NEED IS LOVE”, a novel six-week, self-directed patient education manual designed to improve chronic kidney disease knowledge/self-management, health care transition readiness, self-advocacy, and mindfulness skills among adolescents with chronic kidney disease. Design and methodsWe enrolled 49 adolescents aged 11–17 years (mean age 14.7 ± 1.9; 53.1% males) from a university hospital kidney center who had CKD stages 3 and greater, who were randomly assigned into the “ALL YOU NEED IS LOVE” patient education only group (n = 31) or the “ALL YOU NEED IS LOVE” patient education plus mindfulness training group (n = 18). Participants completed Qualtrics surveys at baseline, post-intervention, and three-month follow-up. The survey included measures of outcome variables (i.e., self-management/transition readiness, patient self-advocacy, and mindfulness), and an additional demographic questionnaire was included in the baseline survey. Multilevel model analyses were used to examine the effects of group and time on the outcome variables. ResultsMultilevel model analyses showed an overall significant time effect across all outcome variables in both groups. However, the group effects were not statistically significant across the outcome variables. ConclusionsBoth interventions significantly increased participants' self-management/HCT readiness, self-advocacy, and mindfulness over time. Mindfulness training may not bring additional benefits to the “ALL YOU NEED IS LOVE” education manual. Practice implicationsPediatric nurses and clinicians may utilize the self-directed “ALL YOU NEED IS LOVE” manual to increase self-management/transition readiness, self-advocacy, and mindfulness among adolescents with chronic kidney disease.

Stressors and Destressors in Working From Home Based on Context and Physiology From Self-Reports and Smartwatch Measurements: International Observational Study Trial.

The COVID-19 pandemic has greatly boosted working from home as a way of working, which is likely to continue for most companies in the future, either in fully remote or in hybrid form. To manage stress levels in employees working from home, insights into the stressors and destressors in a home office first need to be studied. We present an international remote study with employees working from home by making use of state-of-the-art technology (ie, smartwatches and questionnaires through smartphones) first to determine stressors and destressors in people working from home and second to identify smartwatch measurements that could represent these stressors and destressors. Employees working from home from 3 regions of the world (the United States, the United Kingdom, and Hong Kong) were asked to wear a smartwatch continuously for 7 days and fill in 5 questionnaires each day and 2 additional questionnaires before and after the measurement week. The entire study was conducted remotely. Univariate statistical analyses comparing variable distributions between low and high stress levels were followed by multivariate analysis using logistic regression, considering multicollinearity by using variance inflation factor (VIF) filtering. A total of 202 people participated, with 198 (98%) participants finishing the experiment. Stressors found were other people and daily life getting in the way of work (P=.05), job intensity (P=.01), a history of burnout (P=.03), anxiety toward the pandemic (P=.04), and environmental noise (P=.01). Destressors found were access to sunlight (P=.02) and fresh air (P<.001) during the workday and going outdoors (P<.001), taking breaks (P<.001), exercising (P<.001), and having social interactions (P<.001). The smartwatch measurements positively related to stress were the number of active intensity periods (P<.001), the number of highly active intensity periods (P=.04), steps (P<.001), and the SD in the heart rate (HR; P<.001). In a multivariate setting, only a history of burnout (P<.001) and family and daily life getting in the way of work (P<.001) were positively associated with stress, while self-reports of social activities (P<.001) and going outdoors (P=.03) were negatively associated with stress. Stress prediction models based on questionnaire data had a similar performance (F1=0.51) compared to models based on automatic measurable data alone (F1=0.47). The results show that there are stressors and destressors when working from home that should be considered when managing stress in employees. Some of these stressors and destressors are (in)directly measurable with unobtrusive sensors, and prediction models based on these data show promising results for the future of automatic stress detection and management. Netherlands Trial Register NL9378; https://trialsearch.who.int/Trial2.aspx?TrialID=NL9378.