The aim of this work was to investigate the effects of acetyl acetone on Zinc (Zn) uptake and growth of Drumstick (Moringa oleifera) plants. Thirty seedlings were raised in hydroponic solution containing varied concentrations of Zn and acetyl acetone. The results showed a significant (p>0.05) change in weights of the plants when concentrations of Zn and acetyl acetone were added. Plants grown in treated hydroponics died before control plants. Zn uptake and accumulation were dose dependent with respect to addition of both Zn and acetyl acetone. The translocation factor decreased highly insignificantly (P>0.05) at lower concentration of Zn and significant at higher concentration in treated plants compared to control. The chlorophyll, carotenoid and proline content were severely decreased after addition of Zn and acetyl acetone, inducing toxicity symptoms. Thus, acetyl acetone did not play any significant role in alleviating Zn-induced toxicity.