Consequence Of Adaptation Research Articles

Thermophilic waste air treatment of n‐alkanes in a two‐phase bubble column reactor: the effect of silicone oil addition

AbstractBACKGROUNDThermophilic waste air biofiltration was developed to overcome the often observed drop in pollutant removal efficiency caused by classical reactor overheating above the mesophilic temperature range. To date, only a few studies have been reported on thermophilic biofiltration of airborne hydrophobic pollutants. In this work, a bubble column reactor (BCR) operated at 50 °C was used to treat waste air contaminated by a mixture of gasoline/kerosene range n‐alkanes with a microbial consortium acquired from burning coal dumps.RESULTSSeveral strategies were used to increase the low pollutant removal efficiency initially observed. Of these, only the addition of NAP (silicone oil) to the reactor led to increased removal efficiency, due to formation of water‐in‐oil emulsion. Analysis of the microbial consortium revealed bacteria from the Paenibacilaceae family (FN667384) and unidentified thermophilic fungi (HQ693517.1) to be the dominant organisms within the analyzed category, with 48% and 99% abundance, respectively. In the presence of NAP, longer‐chain n‐alkanes (C10–C12) were degraded efficiently, unlike their shorter‐chain homologs. After 7–10 days, the degradation of shorter‐chain C7–C8 n‐alkanes was observed at the expense of their longer‐chain homologs.CONCLUSIONA two‐phase thermophilic BCR proved successful in treating an airborne n‐alkane mixture. With the NAP addition, the apparent mass transfer limitations were overcome, creating a suitable environment for thermophilic hydrocarbon biodegradation. As a result, efficient degradation of longer‐chain n‐alkanes was enabled upon emulsification, whereas the removal of shorter‐chain C7–C8 hydrocarbons occurred later, most likely as a consequence of the biomass adaptation. © 2021 Society of Chemical Industry

Vulnerability assessment of crop production to climate change across Northwest China during 1995–2014

Crop production vulnerability to climate change in Northwest China depends upon multiple socio-ecological factors. Knowledge regarding the specific indicators and methods suitable for assessing crop production vulnerability is limited that address spatiotemporal variations across large and diverse zones. We propose an integrated assessment framework to quantify the vulnerability of crop production derived from crop yield sensitivity, exposure, and adaptive consequences across 338 counties in Northwest China during 1995–2014. Maps on these indices were generated using climatic and socioeconomic data with spatial mapping method. Different clusters of crop production vulnerability were then identified by a k-means cluster method to assess the heterogeneity of vulnerability at a regional scale. Results show that the vulnerability of crop production in 338 counties varies significantly in both geographical and socioeconomic aspects, specifically, vulnerability indicators are generally higher in Minhe, Menyuan, Hualong, and Ledu, and Xayar had the lowest value of vulnerability. This indicates that adaptation strategies for regional crop production need to focus on several levels, from the improvement of adaptive ability to crop yield fluctuation by promoting irrigation agriculture and optimizing limited water resources in typical arid areas, to agriculture-related financial policies incentivizing the capital investment and technology upgrade of crop production on traditional farming regions. This study provides convincing evidence that the factors related to socioeconomic policies are particularly alarming when a crop’s risk is compared to precipitation fluctuations. We recommend these findings be used to facilitate regional agriculture planning to reduce crop production vulnerability and ensure sustainable food security in specific regions.

Consistent community genetic effects in the context of strong environmental and temporal variation in Eucalyptus.

Provenance translocations of tree species are promoted in forestry, conservation, and restoration in response to global climate change. While this option is driven by adaptive considerations, less is known of the effects translocations can have on dependent communities. We investigated the relative importance and consistency of extended genetic effects in Eucalyptus using two species-E. globulus and E. pauciflora. In E. globulus, the dependent arthropod and pathogen canopy communities were quantified based on the abundance of 49 symptoms from 722 progeny from 13 geographic sub-races across 2 common gardens. For E. pauciflora, 6 symptoms were quantified over 2 years from 238 progeny from 16 provenances across 2 common gardens. Genetic effects significantly influenced communities in both species. However, site and year effects outweighed genetic effects with site explaining approximately 3 times the variation in community traits in E. globulus and site and year explaining approximately 6 times the variation in E. pauciflora. While the genetic effect interaction terms were significant in some community traits, broad trends in community traits associated with variation in home-site latitude for E. globulus and home-site altitude for E. pauciflora were evident. These broad-scale trends were consistent with patterns of adaptive differentiation within each species, suggesting there may be extended consequences of local adaptation. While small in comparison to site and year, the consistency of genetic effects highlights the importance of provenance choice in tree species, such as Eucalyptus, as adaptive divergence among provenances may have significant long-term effects on biotic communities.

Consequences of adaptation of TAL effectors on host susceptibility to Xanthomonas.

Transcription activator-like effectors (TALEs) are virulence factors of Xanthomonas that induce the expression of host susceptibility (S) genes by specifically binding to effector binding elements (EBEs) in their promoter regions. The DNA binding specificity of TALEs is dictated by their tandem repeat regions, which are highly variable between different TALEs. Mutation of the EBEs of S genes is being utilized as a key strategy to generate resistant crops against TALE-dependent pathogens. However, TALE adaptations through rearrangement of their repeat regions is a potential obstacle for successful implementation of this strategy. We investigated the consequences of TALE adaptations in the citrus pathogen Xanthomonas citri subsp. citri (Xcc), in which PthA4 is the TALE required for pathogenicity, whereas CsLOB1 is the corresponding susceptibility gene, on host resistance. Seven TALEs, containing two-to-nine mismatching-repeats to the EBEPthA4 that were unable to induce CsLOB1 expression, were introduced into Xcc pthA4:Tn5 and adaptation was simulated by repeated inoculations into and isolations from sweet orange for a duration of 30 cycles. While initially all strains failed to promote disease, symptoms started to appear between 9-28 passages in four TALEs, which originally harbored two-to-five mismatches. Sequence analysis of adapted TALEs identified deletions and mutations within the TALE repeat regions which enhanced putative affinity to the CsLOB1 promoter. Sequence analyses suggest that TALEs adaptations result from recombinations between repeats of the TALEs. Reintroduction of these adapted TALEs into Xcc pthA4:Tn5 restored the ability to induce the expression of CsLOB1, promote disease symptoms and colonize host plants. TALEs harboring seven-to-nine mismatches were unable to adapt to overcome the incompatible interaction. Our study experimentally documented TALE adaptations to incompatible EBE and provided strategic guidance for generation of disease resistant crops against TALE-dependent pathogens.

Antimicrobial Resistance in the Context of the Sustainable Development Goals: A Brief Review.

The reduction in infectious disease morbidity and mortality may be attributed to a variety of factors; however, improved sanitation and public health, and the introduction of vaccines and antibiotics are among the most significant. The development of antimicrobial resistance (AMR) in bacterial pathogens is an expected consequence of evolutionary adaptation to these noxious agents and the widespread use of these drugs has significantly sped up this process. Infections caused by multidrug resistant pathogens are directly associated with worse clinical outcomes, longer hospital stays, excess mortality in the affected patients and an increasing burden and costs on the healthcare infrastructure. The Sustainable Development Goals (SDGs) were published in 2015 by the United Nations to serve as a global blueprint for a better, more equitable, more sustainable life on our planet. The SDGs contextualize AMR as a global public health and societal issue; in addition, the continuing emergence of AMR may limit the attainment on many SDGs. The aim of this mini-review is to provide insight on the interface between attainment of SDGs and the clinical problem of drug resistance in bacteria.

Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations.

Laboratory experimental evolution provides a window into the details of the evolutionary process. To investigate the consequences of long-term adaptation, we evolved 205 Saccharomyces cerevisiae populations (124 haploid and 81 diploid) for ~10,000,000 generations in three environments. We measured the dynamics of fitness changes over time, finding repeatable patterns of declining adaptability. Sequencing revealed that this phenotypic adaptation is coupled with a steady accumulation of mutations, widespread genetic parallelism, and historical contingency. In contrast to long-term evolution in E. coli, we do not observe long-term coexistence or populations with highly elevated mutation rates. We find that evolution in diploid populations involves both fixation of heterozygous mutations and frequent loss-of-heterozygosity events. Together, these results help distinguish aspects of evolutionary dynamics that are likely to be general features of adaptation across many systems from those that are specific to individual organisms and environmental conditions.

A Morphofunctional Hypothesis for Selection on EDAR V370A and Associated Elements of Sinodonty

The phenomenon of sinodonty refers to a suite of dental characters shared between East Asian and Native American populations, and most prominently to the presence of shoveled incisors. Although this syndrome is a conspicuous aspect of dental differentiation among extant human populations, elements of which have been recent subject of detailed genetic analysis, adaptive consequences of shoveled incisors and related features remains unclear. Here, I hypothesize that many of the associated differences in dentition (along with reduction in mandibular length and increases in salivary gland branching) arose in parallel with the opportunistic consumption of wild rice and millet in central and northern China, respectively, and with their subsequent domestication in the Upper Paleolithic. More efficient mastication and digestion of plant grains (and of other starchy foods obtained via broad-spectrum foraging) would potentially have been enabled by these traits, yielding greater rates of nutritional intake as wild crops were progressively domesticated. This functional hypothesis, although not mutually exclusive relative to other proposed selective factors, matches the estimated timeline in China for both origin and time to fixation of the associated allele (EDAR V370A), and is consistent with chronic energetic gain and fitness benefits independent of any assumptions for concurrent climatic conditions.

“It’s as if I’m the one suffering”: Narratives of Parents of Children with Disability in the Philippines

Background. Children comprise a significant proportion of persons with disabilities (PWDs) in the Philippines, and represent a major public health challenge. One under-explored topic is the “lived experiences” of their parents and guardians as well as the roles they play in caring for their children. This qualitative study responds to this research gap by eliciting and foregrounding their experiences and narratives. Methods. Six focus group discussions (FGDs) were conducted among parents of children with disabilities (CWDs) in Davao City and Tagum City. These were complemented by 12 key informant interviews among healthcare providers in both cities. Results. For many parents, coming to terms with a disability is a difficult and lengthy process, but one that ends with a measure of relief and eventual adaptation. Living with disability, meanwhile, is fraught with medical, financial, educational, and social challenges. A positive religious outlook allows them to make sense of disability, helping them to overcome these challenges. Support groups and the health care system are likewise crucial factors towards family resilience. Conclusion. Our findings show that the experience of disability is shared among family members, particularly, the parents of CWDs; thus, underscoring the need for a family-centered approach in policies, clinical care, and communications efforts involving children with disability in the Philippines.

Intervenir en tiempos de pandemia. Adaptaciones metodológicas y condiciones laborales en el “Programa Familias”

The programa Familias is the most important public policy to combat poverty in the Chilean State. The psychosocial and socio-labor accompaniment by the Apoyos Familiares Integrales is a crucial part of their intervention methodology, based on visits to the homes of the user families. Due to the crisis unleashed by the COVID19 pandemic, the face to face accompaniment had to be modified by a telephone accompaniment, in a methodological adaptation effort that seeks to give continuity to the intervention of the programa Familias. Likewise, the health emergency evidenced the challenging working conditions in which the professionals in charge of this intervention work and the fragility of government strategies to overcome poverty. Based on the analysis of 31 interviews carried out whit professionals who work in this public policy at the municipal level, during the first months of the pandemic, we explore the consequences of the methodological adaptation, its limitations, and the effects of teleworking on the Apoyos Familiares Integrales and on the intervention itself.

Materiality, inequality, and future‐making as focal points of future engagement of economic anthropology with climate change

Materiality, inequality, and future‐making as focal points of future engagement of economic anthropology with climate change

Intervenir en tiempos de pandemia. Adaptaciones metodológicas y condiciones laborales en el “Programa Familias”

The programa Familias is the most important public policy to combat poverty in the Chilean State. The psychosocial and socio-labor accompaniment by the Apoyos Familiares Integrales is a crucial part of their intervention methodology, based on visits to the homes of the user families. Due to the crisis unleashed by the COVID19 pandemic, the face to face accompaniment had to be modified by a telephone accompaniment, in a methodological adaptation effort that seeks to give continuity to the intervention of the programa Familias. Likewise, the health emergency evidenced the challenging working conditions in which the professionals in charge of this intervention work and the fragility of government strategies to overcome poverty. Based on the analysis of 31 interviews carried out whit professionals who work in this public policy at the municipal level, during the first months of the pandemic, we explore the consequences of the methodological adaptation, its limitations, and the effects of teleworking on the Apoyos Familiares Integrales and on the intervention itself.

Neuroinflammation as a pathophysiological factor in the development and maintenance of functional seizures: A hypothesis.

The neurobiological underpinnings of functional seizure (FS) development and maintenance represent an active research area. Recent work has focused on hardware (brain structure) and software (brain function and connectivity). However, understanding whether FS are an adaptive consequence of changes in brain structure, function, and/or connectivity is important for identifying a causative mechanism and for FS treatment and prevention. Further, investigation must alsouncover what causes these structural and functional phenomena. Pioneering work in the field of psychoneuroimmunology has established a strong, consistent link between psychopathology, immune dysfunction, and brain structure/function. Based on this and recent FS biomarker findings, we propose a new etiologic model of FS pathophysiology. We hypothesize that early-life stressors cause neuroinflammatory and neuroendocrine changes that prime the brain for later FS development following secondary trauma (e.g., traumatic brain injury or psychological trauma). This framework coalesces existing knowledge regarding brain aberrations underlying FS and established neurobiological theories on the pathophysiology of underlying psychiatric disorders. We also propose brain temperature mapping as a way of indirectly visualizing neuroinflammation in patients with FS, particularly in emotion regulation, fear processing, and sensory-motor integration circuits. We offer a foundation on which future research can be built, with clear recommendations for future studies.

Endothelial dysfunction and its role in the prevention, treatment and complications of critical conditions in obstetrics

Background. Preeclampsia (PE) remains the leading cause of maternal and perinatal morbidity and mortality. As of today, there is no treatment for PE, and the childbirth is the only way to completely eliminate this condition. However, early childbirth is associated with a high risk of fetal morbidity and mortality.
 Objective. To describe the role of endothelial dysfunction (ED) in the development of PE and the possibility of its correction; to evaluate the effectiveness of Tivortin (“Yuria-Pharm”) in the correction of uterine-fetal-placental dysfunction.
 Materials and methods. Analysis of literature sources on this topic; own PLACENTA study. The study involved 535 women with mild PE at 26-29 weeks of gestation. Group I received standard therapy, group II – standard therapy in combination with Tivortin (4.2 g per day for 7-10 days).
 Results and discussion. Until the fetus reaches viability, PE treatment is aimed at correcting hypertension, however, antihypertensive therapy does not have a beneficial effect on the condition of the kidneys and placental blood flow. Decreased blood flow in placenta leads to the syndrome of limited fetal development (SLFD) and multisystem ED. The development of PE is inextricably linked with the systemic damage to maternal endothelial cells and a further decrease in endothelium-dependent vasodilators, which promotes vasospasm and activates the coagulation cascade. PE is accompanied by the imbalance in the systems of prostacyclin and nitric oxide (NO), as well as thromboxane and endothelin. Superficial placentation with insufficient remodeling of the spiral arteries and impaired response to changes in blood flow is one of the main causes of PE. ED is the most studied pathogenetic mechanism of PE. NO has a potent vasodilating effect and is involved in inhibiting thromboxane formation, platelet aggregation and stimulating prostacyclin formation. NO-synthase of endothelial cells, the substrate of which is L-arginine, is the main enzyme of NO production. Disorders of vasodilation in pregnant women with PE can be eliminated by prescribing L-arginine. Literature data show that L-arginine is successfully used in the need to continue pregnancy, as well as to eliminate hypertension and correct SLFD. Canadian guidelines for the treatment of hypertensive complications of pregnancy state that L-arginine is able to improve uteroplacental blood flow. According to a study by J. Chen (2016), the inclusion of L-arginine contributes to both maternal and perinatal outcomes of pregnancy. The effect of L-arginine on fetal growth is mediated by promoting the production of creatine, skeletal muscle protein and growth hormone. L-arginine also promotes the synthesis of polyamines, which can stimulate the growth and development of placenta. Own studies have shown that the use of L-arginine (Tivortin, “Yuria-Pharm”) in the combined PE therapy had improved the growth rate of the fetus and its functional condition, which allowed to prolong pregnancy to the optimal term of childbirth, as well as improve the consequences of childbirth and adaptation of newborns in the early neonatal period. PE is not the only field of application of Tivortin: its intravenous administration in community-acquired pneumonia and pyelonephritis of pregnant women helps to quickly eliminate the pathological process. The results of the PLACENTA study found that Tivortin helped to improve uterine-fetal-placental blood flow and reduce the centralization of blood circulation. In the Tivortin group there was a smaller number of cesarean sections, a tendency to lower blood loss (by 19.5 %), a higher average score of newborns on the Apgar scale. Comparison of clinical and morphological changes showed that the administration of Tivortin in the late second and early third trimester of pregnancy reduces the likelihood of premature placental maturation by 2.1 %, halves the likelihood of placental necrosis, 10 times reduces the signs of hypoxia.
 Conclusions. 1. ED, caused by a decrease in NO, is the main link in the PE pathogenesis. 2. In the human body NO is produced from L-arginine. 3. The use of L-arginine (Tivortin) improves uterine-fetal-placental blood flow, growth rate and functional status of the fetus, reduces fetal distress and allows to prolong pregnancy to the optimal term of childbirth.

Reconciling competing mechanisms posited to underlie auditory verbal hallucinations.

Perception is not the passive registration of incoming sensory data. Rather, it involves some analysis by synthesis, based on past experiences and context. One adaptive consequence of this arrangement is imagination-the ability to richly simulate sensory experiences, interrogate and manipulate those simulations, in service of action and decision making. In this paper, we will discuss one possible cost of this adaptation, namely hallucinations-perceptions without sensory stimulation, which characterize serious mental illnesses like schizophrenia, but which also occur in neurological illnesses, and-crucially for the present piece-are common also in the non-treatment-seeking population. We will draw upon a framework for imagination that distinguishes voluntary from non-voluntary experiences and explore the extent to which the varieties and features of hallucinations map onto this distinction, with a focus on auditory-verbal hallucinations (AVHs)-colloquially, hearing voices. We will propose that sense of agency for the act of imagining is key to meaningfully dissecting different forms and features of AVHs, and we will outline the neural, cognitive and phenomenological sequelae of this sense. We will conclude that a compelling unifying framework for action, perception and belief-predictive processing-can incorporate observations regarding sense of agency, imagination and hallucination. This article is part of the theme issue 'Offline perception: voluntary and spontaneous perceptual experiences without matching external stimulation'.

Transitions in loneliness in later life: the role of social comparisons and coping strategies

AbstractThis study explored the coping strategies and social comparisons used by older adults on different loneliness trajectories (decreased loneliness, stable loneliness and degenerating loneliness). The adaptive consequences of social comparison in later life are recognised as an important strategy for preserving life satisfaction regardless of age-related losses. Coping strategies are also important in managing loneliness. Narrative interviews were conducted with lonely older adults (N = 11) who had participated in Wave One of the Maintaining Function and Well-being in Later Life Study Wales (CFAS Wales). The study found key differences in the coping strategies employed by older adults on different loneliness trajectories. Differences in coping styles between those who reported decreased loneliness and those who were chronically lonely stemmed from perceptions as to whether loneliness was modifiable or not. Different types of social comparison were also found to modulate the loneliness experience. The findings indicate that higher-order strategies (problem, emotional and meaning focused) are not distinct entities but are part of a dynamic process. The management of loneliness in later life may be dependent on several factors, including older adults’ interpretations of the cause of loneliness. These interpretations will have implications for interventions aimed at alleviating chronic loneliness, where the focus may have to be on changing older adult's perceptions of unmodifiable loneliness.

Plant Regeneration Above the Species Elevational Leading Edge: Trade-Off Between Seedling Recruitment and Plant Production

Mountains and their biota are highly threatened by climate change. An important strategy alpine plants use to escape this change consists in seed dispersal and the ability of seeds to germinate and establish in new sites at higher elevation. Little is known about the environmental factors that can affect the regeneration of plants above the elevational limit of growth. We present the first field evidence of recruitment success and plant performance in consequence of upward shift from the alpine to the nival life zone. Seeds of four alpine grassland species were sown at the current elevational limit of growth (site A) and 200 m upward, in a nival environment (site N) located in the Italian Alps. At site N part of the seeds were subjected to experimental manipulation of temperature (using an Open Top Chamber, OTC) or soil (using soil from site A). Recruitment success, soil surface temperature and water potential were monitored for five consecutive years. At the end of the experiment, vegetative growth and foliar traits were measured on individuals from all treatments. Mean annual soil surface temperature and length of the growing season at site A were ca. 2 °C higher and ca. 44 d longer than at site N. Seedling emergence and seedling establishment generally were higher at N (with or without OTC) on local soil than at site A or at site N with soil originating from site A. Conversely, production was higher at site A and at site N with soil originating from site A. Recruitment success above the elevational leading edge was enhanced by coarser and nutrient-poor soil, which promoted seedling emergence and establishment but constrained plant growth. This trade-off between seedling recruitment and plant production underlines adaptive consequence and environmental filtering, both critical to forecast community assembly and responses of alpine species to climate warming.

Climate Change: Causes, Risks, Consequences, Problems of Adaptation and Management (CLIMATE-2019)

The conference “Climate Change: Causes, Risks, Consequences, Problems of Adaptation and Management” was held in Moscow in November 2019. The results of various areas of climate research were presented at the conference, including the diagnosis of modern climate change based on observational data, reanalysis and paleoreconstructions; modeling of current and future climate change; risk assessment of extreme climatic events; determination of the relative role of natural and anthropogenic factors in climate change; studies of the socio-economic consequences of climate change and adaptation to them. The conference was attended by 214 participants from 46 organizations of the Russian Academy of Sciences, Roshydromet, universities and others. 72 oral reports were presented, including 15 invited talks, and 86 poster presentations.List of titles 1. Diagnosis of modern climate changes based on observational data, reanalysis, and paleoreconstructions. 2. Modeling of modern and future climate change. 3. The risk of extreme climatic events. 4. The relative role of natural and anthropogenic factors in climate change. 5. Socio-economic consequences of climate change and adaptation to them are available in this pdf.

Teachers' Psychological Needs Satisfaction and Thwarting: Can They Explain Students' Behavioural Engagement in Physical Education? A Multi-Level Analysis.

Students’ engagement in Physical Education has been linked to several adaptive consequences. Even though the existing literature suggests that perceived autonomy support can predict engagement, research is scarce on how teachers’ antecedents might influence this behavioural outcome. This study sought to compare the influence of teachers’ basic psychological needs’ satisfaction and basic psychological needs’ thwarting on students’ behavioural engagement and on the relationship between perceived autonomy-support and the students’ behavioural engagement. The sample included 29 Physical Education teachers and 644 students who were taught by the participants teachers. Data were collected using both paper and online surveys and they were analysed using multilevel modelling techniques. The results revealed that, while teachers’ autonomy satisfaction might be significant in the explanation of students’ engagement (β = 0.33, p < 0.01), it seems that needs thwarting could be a better predictor of this outcome (β autonomy thwarting = −0.17, p < 0.01; β competence thwarting = −0.06, p < 0.05). These findings suggest the impact of certain external pressures on teachers’ practices which, in turn, might affect students’ behavioural outcomes.

Moving up or going under? Differential livelihood trajectories in coastal communities in Vietnam

• Dynamics of livelihoods in small-scale fishery communities in Vietnam significantly changed with the introduction of aquaculture. • Three distinct livelihood trajectories – Accumulating, fluctuating, and marginalizing - emerged among fisheries-dependent communities. • Adoption of aquaculture as a new livelihood strategy has benefited the adopters but caused detrimental consequences fishing households. • Recognising differential livelihood trajectories and struggles is essential for designing equitable adaptation policies. Transformations from artisanal fishing to aquaculture are now ubiquitous in many small-scale coastal fishing communities worldwide, often in response to the economics of fisheries and climate change. Understanding the long-term dynamics of community livelihoods is an important step in designing appropriate fishery management and adaptation policies to navigate the effects of such transformations. The literature has focused predominantly on addressing snapshots of livelihood conditions, with less attention being paid to how present conditions have emerged over time, and for whom. Using an integrated analytical approach, this study investigates the longitudinal livelihood trajectories in two small-scale fishery villages around the Tam Giang Lagoon in Vietnam, with particular attention paid to the changes since the introduction of aquaculture in the late 1980s. Three distinct livelihood trajectories — accumulating, fluctuating, and marginalising — represent the differential pathways available to fishing- and aquaculture-dependent households. In this constrained yet shared resource space, the transformational adaptation through aquaculture has benefitted the adopters and enhanced their livelihood resilience; yet, it has had detrimental consequences for the artisanal fishers who find themselves locked into a state of heightened vulnerability. The findings provide evidence of differential and unintended consequences of new adaptations to livelihood struggles in small-scale fishery communities, and they point to the need for well-targeted policies to reduce rather than exacerbate growing inequalities. Fishery management policies and interventions in this lagoon, and similar contexts, need to take into account the heterogeneity in livelihood trajectories and unequal social vulnerability to inform more just adaptation strategies and improve the wellbeing of fishery communities.

Ecological and Evolutionary Consequences of Anticancer Adaptations.

SummaryCellular cheating leading to cancers exists in all branches of multicellular life, favoring the evolution of adaptations to avoid or suppress malignant progression, and/or to alleviate its fitness consequences. Ecologists have until recently largely neglected the importance of cancer cells for animal ecology, presumably because they did not consider either the potential ecological or evolutionary consequences of anticancer adaptations. Here, we review the diverse ways in which the evolution of anticancer adaptations has significantly constrained several aspects of the evolutionary ecology of multicellular organisms at the cell, individual, population, species, and ecosystem levels and suggest some avenues for future research.