In view of the defects of the current mainstream structural safety analysis method of Truss bridge, the safety analysis method at the component level should be further developed. Therefore, it is necessary to carry out the overall safety analysis and structural optimization at the structural level. Based on the concrete data of the actual steel truss beam bridge, this paper uses ABAQUS and MIDAS finite element software to model the truss structure. First of all, the static analysis is carried out, and then the structural analysis and optimization of the steel truss beam bridge is carried out with the elastic modulus reduction method. Based on the linear elastic finite element method, the bearing state of each component is solved, and the ultimate bearing capacity of the whole structure is calculated iteratively. Thus, the limitation of incremental nonlinear finite element method is overcome, and higher calculation accuracy and efficiency are realized.