For further improvement in the technology under laboratory conditions, we studied a possible continuous process of desorption--clarification using the EDE-10PG anionite. For this purpose, during the desorption process from the~s KB-2, ammoniacal e!uates of neomycin were continuously passed through a column charged with the EDE-10PG anionite. Thus, the first slightly active fractions were used for removing water from the anionite, and the slightly active fractions at the end of the desorption, for displacing the active solutions. The continuous desorption-clarification method made it possible to increase the yield of the antibiotic at the stage of clarification, because the vacuum evaporation stage of the ammoniacal eluates before passage through the clarifying anionite is eliminated, and the slightly active eluate fractions are more rationally used. As a result, also the quality of the eluates as regards color was increased, and it was thus possible to simplify the scheme for further purification by eliminating several stages (secondary concentration of the eluates in vacuo, and their secondary 'treatment with charcoal).