Active Period Research Articles

Food addiction and emotional eating are associated with intradaily rest-activity rhythm variability.

The aim of the present investigation was to study the associations among parameters characterizing eating behavior and actimetry-derived indices of circadian rhythm of motor activity. The study involved 81 healthy participants (average age: 21.5 ± 9.6 y, women: 77.8%). Each study participant provided personal data, filled out the Yale Food Addiction Scale and the Dutch Eating Behavior Questionnaire, and wore a wrist actimeter for 7consecutive days to record motor activity. Using time series treatments, we obtained: (a) three cosinor-derived parametric indices [Medline Estimating Statistics of Rhythm (MESOR), amplitude, and acrophase], and (b) four non-parametric indices [interdaily stability, intradaily variability (I.V.), most active 10-h period (M10), and least active 5-h period] characterizing the 24-h rhythm of motor activity. A multiple regression analysis adjusted for age, sex, and BMI was performed to assess the associations among the studied indicators. It was shown that I.V. is a predictor of symptoms of food addiction (β = 0.242, P = 0.037) and emotional eating (β = 0.390, P = 0.004), MESOR is a predictor of symptoms of food addiction (β = 0.342, P = 0.003), and M10 predicts restraint (β = 0.257, P = 0.015) and emotional eating (β = 0.464, P = 0.001). It was shown for the first time that an increase in symptom counts of food addiction is associated with an increase in the average level and fragmentation of 24-h rhythm of motor activity. Level V, cross-sectional descriptive study.

Male reproductive cycle in a population of the endemic butterfly lizard, Leiolepis ocellata Peters, 1971 (Squamata: Agamidae) from northern Thailand

BackgroundFundamental knowledge on the seasonal reproductive microanatomy and endocrinology of reptiles has been collected from several studies of various species. The present study was to determine annual changes in hormonal profiles, and detailed histomorphometric and histochemical characteristics of the entire male reproductive system of the tropical agamid lizard, Leiolepis ocellata.ResultsMale L. ocellata individuals (n = 75) collected from the territory of two provinces (Lampang and Tak) in northern Thailand exhibited annual variation in sex hormonal, histomorphometric, and histochemical characteristics of the male reproductive system. The reproductive cycle was subdivided into eight reproductive periods (early first active, first active, resting, second recrudescent, second active, regressive, quiescent, and first recrudescent), thus displaying a bimodal pattern with two actively reproductive periods. Circulating sex hormones (testosterone, estradiol, and progesterone) peaked in the first active (February) and the second active (June–July) periods. Likewise, gonadosomatic index (GSI) and histomorphometric variables of the testes and of the genital ducts (rete testis, ductuli efferentes, ductus epididymis, and ductus deferens) revealed their highest values in the first active period. Marked increase in protein and carbohydrate production was detectable in the ductuli efferentes during the active periods.ConclusionsThe male reproductive cycle of L. ocellata showed a biannual pattern of the hormonal profile, and detailed histomorphometric and histochemical characteristics of the entire reproductive system. Hence, the present study provides improved basic knowledge on the reptilian reproductive biology with comparative viewpoints to other reptiles.

Impact of maxillofacial growth on implants placed in adults: A narrative review.

To determine the effect of lifetime maxillofacial changes on dental implants placed in adults, analyze the clinical implications of these changes, identify prognostic factors, and offer possible solutions. The relationship between implant placement and maxillofacial changes, occurring during not only the active growth period but also the entire span of adulthood, has not been extensively examined. Vertical differences between implants and adjacent teeth due to the ankylotic behavior of the former might be observed at any age and endanger restoration biologically, functionally, and esthetically. Regarding interproximal contacts, firm contact loss may occur within a few months after restoration, resulting in food impaction. Many prognostic factors have been reported, but most do not exhibit a statistically significant association with implant infraocclusion and interproximal contact loss. Incorporation of alternative solutions, accurate treatment planning, strict recall protocols, and retrievability of implant-supported restorations can facilitate efficient management of complications. Maxillomandibular changes throughout adulthood may lead to complications such as implant infraocclusion and interproximal contact loss. Rehabilitation of edentulism should be characterized by well-designed and flexible treatment plans to resolve long-term complications efficiently. Further long-term clinical studies are needed to identify other risk factors. Treatment plans for implant therapy should be reconsidered for adults. Careful patient monitoring and early intervention are essential for securing treatment outcomes.

Photosynthesis phenology, as defined by solar-induced chlorophyll fluorescence, is overestimated by vegetation indices in the extratropical Northern Hemisphere

Vegetation phenology is highly sensitive to climate change, although the data and methods used to estimate key phenological states can influence this sensitivity. Because of its direct relation to leaf photosynthetic carbon uptake, remotely sensed solar-induced chlorophyll fluorescence (SIF) can provide new insight assessing changes in vegetation phenology. Here, we investigated the potential of using a SIF time series product named contiguous SIF (CSIF) to estimate spring, summer, and autumn phenology in the extratropical Northern Hemisphere (>30°N) and compared the results with those based on Moderate Resolution Imaging Spectroradiometer (MODIS) Normalized Difference Vegetation Index (NDVI) for the period 2001–2018. Overall, we found similar spatial patterns in phenological states. However, specific dates of key phenological events differed when using CSIF vs. MODIS NDVI data. NDVI data indicated that the growing season started earlier (by 10.1 days on average) and ended later (11.5 days on average) relative to CSIF data. This implies that actual periods for photosynthetic activity are shorter (by 21.6 days on average) than those estimated from vegetation indices more directly related to changes in canopy structure. These large differences between results from NDVI and that from CSIF suggest that vegetation indices such as NDVI seem to overestimate the period for active photosynthesis over the extratropical Northern Hemisphere. Furthermore, while phenology of the early growing season is dominated by temperature for both NDVI and CSIF data, phenology of the late growing season is mainly controlled by temperature for NDVI but by precipitation for CSIF. Our findings were further confirmed by other SIF (GOME-2 SIF) and vegetation index (MODIS EVI) datasets. Phenology modes in Earth system modelling are often parameterized using leaf unfolding and senescence from either station or satellite observations. Our results imply that canopy structure-based parameterization schemes may have overestimated photosynthesis active period, and thus productivity responses. We conclude that SIF data offers a novel and unique approach for assessing phenological change - one that is more directly tied to the carbon cycle and how it is being influenced by climate change.

Bipartite Flocking for Cucker-Smale Model on Cooperation-Competition Networks Subject to Denial-of-Service Attacks

This work emphasises the bipartite flocking of leader-follower Cucker-Smale model on cooperation-competition networks under Denial-of-Service (DoS) attacks. The DoS with limited energy is the periodic signal that consists of active periods and asleep periods. It interruptes the information interactions among agents during the activation stages, while it concentrates on storing own energy for the next attack moment during the asleep stages. Meanwhile, the control strategy to defend against DoS attacks is established. The products convergence of infinite sub-stochastic matrices method is employed to implement the bipartite flocking behavior. Based on this method, a algebraic condition which is related to initial states, the topological structure and the weight function is constructed. Moreover, the obtained theoretical results are demonstrated by numerical simulations.

Back-arc basin closure at the East Asian margin during Permo-Triassic boundary: Evidence from geochemistry and U-Pb zircon data of sedimentary breccia from Maizuru Terrane, Southwest Japan

The paleo Maizuru back-arc basin, which was located at the East Asian continental margin opened in Early Permian times and closed during the Permo-Triassic (P-T) boundary. The back-arc basin sediments are exposed in the present-day Maizuru Terrane located in Southwest Japan and hold the key to understand the tectonic evolution of both this back-arc basin and that of the East Asian continental margin. The opening of the Maizuru back-arc basin was accompanied by the deposition of a massive black mudstone-dominated formation, presently recognized as the Maizuru Group. The closure of the back-arc basin which was accompanied by the deposition of coarse-grained materials such as the Tonoshiki breccia made up of differently-sized extremely angular clasts implies that the P-T boundary was a tectonically active period in the Maizuru Terrane. Petrographical and geochemical studies revealed that Tonoshiki breccia can be divided into two main types, a first type mainly made up of mafic to intermediate rock clast fragments (Type I) and a second type mostly consisting of felsic rock clast materials (Type II). Both types commonly contain massive black mudstone clasts that were derived from the underlying Maizuru Group. The U-Pb detrital zircon geochronology of those two types of breccia suggests that they were deposited during two phases of the tectonic activity-induced debris flow that occurred at ca. 259 Ma and ca. 251 Ma for the first and second type, respectively. Type I was sourced from the Southern zone, whereas Type II was sourced mostly from the Northern zone of the Maizuru Terrane. This switch of provenance testifies to the intense tectonic activity that reigned during the P-T boundary. The closure of the Maizuru back-arc basin was induced by the subduction of the basement crust of the basin under the East-Asian continent during the P-T boundary.

SOSIALISASI DAN EDUKASI KEPADA ORANG TUA TENTANG ANAK AKTIF DAN HIPERAKTIF USIA DIBAWAH 12 TAHUN DI DESA SUKA NEGRI

Children under the age of 12 are the active period of a child and the time for these children to be free to move and be active. Time to be free to play and free to enjoy playing with their peers. Active children are children who are free to move, always move without obstacles from all things, especially in terms of their motor system. Children who are active even though they do a lot of movement, they are still able to focus on what they are doing. Hyperactive children are children who have activity beyond the active limits of normal children in general. Please note that hyperactive children are very difficult to focus attention, even controlling their body movements is very difficult. Children who are classified as hyperactive tend to be called children who have disorders and even require special treatment or therapy to deal with them. And also to distinguish active and hyperactive children, it is necessary to have several procedures, cannot directly diagnose a child into the hyperactive child group. The method in this scientific process is the process of socialization and education. Here the author provides some material about active and hyperactive children as well as education on how to handle them. Parents who have children in Suka Negri village are able to understand what an active child is and what its characteristics are, as well as how to handle and distinguish between an active child and a hyperactive child

The impact of mothers working shift patterns with emotional behavior of preschool age children at RSUD dr Saiful Anwar Malang

Introduction: Children’s social-emotional development includes the development of emotions, personality, and interpersonal relationships. Preschoolers are in an active period in personality formation and social development. Children's social-emotional development is influenced by several factors: interaction in the family, especially with the mother. Mother is a central figure who plays an essential role in meeting the welfare and needs of family members. The child's interaction with the mother will be disturbed when the mother is working. Objectives: This study aims to determine the relationship between working mothers and shift patterns in the emotional behavior of preschoolers. Methods: The research design used is correlation analytic with a cross-sectional approach. Irna IV Hospital dr. Saiful Anwar Malang, who has preschool-age children, is the population in this study. The sampling method is purposive sampling. The instrument used is the impact of the mother's work shift pattern and emotional behavior problems. Spearman's Rank test determines the relationship between the two variables. Results: Of the 54 employees recruited in this study. The analysis results showed a significant relationship p = 0.000 <0.05 between the two variables, with a strong correlation value (r = 0.67). Conclusions: there is a significant relationship between working mothers and shift patterns in the quality of interaction with children. Disturbance of mother-child interaction affects children's emotional behavior, especially in preschoolers.

Spatio-temporal characteristics of hazardous weather affecting Chinese airports based on the ERA5/ERA5-land reanalysis dataset

The growing demand for air transportation has led to increased air traffic and airline operations at airports worldwide, while hazardous weather conditions have a considerable impact on the efficiency and safety of air traffic. The long-term and high-resolution state-of-art fifth-generation reanalysis of the European Center for Medium-Range Weather Forecasts (ECMWF) (ERA5) and ERA5-land provide us a perspective on the climatological characteristics of hazardous weather conditions affecting Chinese airports. These hazardous weather conditions include low-level wind shear (LLWS), limited visibility (LIMV), thunderstorms (TSTMs), and snowfall (SNOW). The LLWS is frequent in winter but rare in summer. At the airports in the north of eastern China, managers should take more precautions about LLWS from February to March and October to November. LIMV is major hazardous weather in the south of eastern China that should be carefully monitored in winter, especially from December to January. In northwestern China, LIMV is rare, especially at Yinchuan and Lanzhou airports. TSTMs frequently occur in South China and Southwest China, especially in Yunnan, Guangxi, Guangdong, and eastern Tibet. The corresponding active period is summer. SNOW frequently occurs over the Tibet Plateau and parts of Xinjiang province. SNOW is generally active in early winter (December–January) at Urumchi airport but at Lhasa airport in late winter (February–March). There is no SNOW throughout the year in the south of eastern China. The observations also verify such characteristics of the annual cycles of the four hazardous weather conditions. The trend analysis does not express many warnings on hazardous weather conditions except the SNOW. The SNOW at Lhasa airport shows an increasing trend. Considering the frequent SNOW in Lhasa, more attention should be put to monitoring this weather here.

Evaluation of Multi-layer Perceptron Neural Networks in Predicting Ankle Dorsiflexion in Healthy Adults using Movement-related Cortical Potentials for BCI-Neurofeedback Applications.

Brain computer interface (BCI) systems were initially developed to replace lost function; however, they are being increasingly utilized in rehabilitation to restore motor functioning after brain injury. In such BCI-mediated neurofeedback training (BCI-NFT), the brain-state associated with movement attempt or intention is used to activate an external device which assists the movement while providing sensory feedback to enhance neuroplasticity. A critical element in the success of BCI-NFT is accurate timing of the feedback within the active period of the brain state. The overarching goal of this work was to develop a reliable deep learning model that can predict motion before its onset, and thereby deliver the sensory stimuli in a timely manner for BCI-NFT applications. To this end, the main objective of the current study was to design and evaluate a Multi-layer Perceptron Neural Network (MLP-NN). Movement-related cortical potentials (MRCP) during planning and execution of ankle dorsiflexion was used to train the model to classify dorsiflexion planning vs. rest. The accuracy and reliability of the model was evaluated offline using data from eight healthy individuals (age: 26.3 ± 7.6 years). First, we evaluated three different epoching strategies for defining our 2 classes, to identify the one which best discriminated rest from dorsiflexion. The best model accuracy for predicting ankle dorsiflexion from EEG before movement execution was 84.7%. Second, the effect of various spatial filters on the model accuracy was evaluated, demonstrating that the spatial filtering had minimal effect on model accuracy and reliability.

High urinary CXCL10/Cr with onset of Burkitt lymphoma in a pediatric kidney transplant recipient

Urinary CXCL10/Cr is a promising diagnostic tool for early detection of TCMR in pediatric transplant recipients, and most studies focus on its utility in the context of localized allograft inflammation thus far. Other sources of inflammation that may be detected by CXCL10 are less clear. We present a case review of a patient with BL, who was enrolled in a prospective trial of urinary CXCL10 monitoring. To evaluate the potential confounding, we tested for association of CXCL10/Cr and EBV viral load in a prospective cohort of pediatric transplant recipients with serial testing for urinary CXCL10/Cr. This report describes a 15-year-old boy, 3.5 years post-transplant with chronic EBV viremia, stable kidney function and no history of rejection. Urinary CXCL10/Cr level increased acutely to 79.43 ng/mmol, 0.8 months prior to onset of BL, identified by a surge in EBV viral load. In a national cohort of 97 pediatric kidney transplant recipients, there was no association between urinary CXCL10/Cr with EBV viral loads when comparing periods of pre-viremia (5.8± 9.2ng/mmol) to active viremia (4.0± 5.3ng/mmol) and periods of active viremia (7.1± 8.9ng/mmol) to post-viremia (4.4± 9.8ng/mmol). Acute rise in urinary CXCL10/Cr was associated with onset of graft-associated BL. We were not able to confirm a general association of EBV viral load and urinary CXCL10. As non-invasive monitoring is implemented using biomarkers like CXCL10 in the clinic, attention will be needed to identify other uncommon, potential sources of CXCL10 elevation.

Changes in the Differentiation Program of Birch Cambial Derivatives following Trunk Girdling

The mechanisms regulating the tree trunk radial growth can be studied in original experiments. One technique for studying cambium activity (the meristem involved in radial growth) under conditions of an increased photoassimilate level is trunk girdling. We girdled the trunks of 17- to 22-year-old silver birch plants (Betula pendula Roth var. pendula) during the active growth period and collected xylem and phloem samples at two height levels (1 cm and 35 cm) above girdle, 10, 20, and 30 days after girdling. We investigated the changes that occurred at the anatomical level, as well as the activities of sucrose-metabolizing enzymes and antioxidant-system enzymes and the expression of genes that encode proteins involved in sucrose and auxin transport and metabolism. A moderate increase in photoassimilates (35 cm above the girdle) resulted in a change in the ratio of phloem to xylem increments and an increase in the proportion of parenchyma in the conducting tissues. The increase of photoassimilates above the level at which they can be used in the processes of normal tissue growth and development (1 cm above the girdle) led to xylogenesis suppression and the stimulation of phloem formation, a significant increase in the parenchyma proportion in the conducting tissues, and formation of large sclereid complexes. The differentiation of parenchyma and sclereid cells coincided with biochemical and molecular markers of abnormal conducting tissue formation in Karelian birch, which are also characterized by high proportions of parenchyma and sclereid near the cambium. The results obtained are important in understanding the cambium responses to the photoassimilate distribution changes and estimating tree productivity and survival under changing environmental conditions.

Sympathoexcitatory responses to renal chemosensitive stimuli are exaggerated at nighttime in rats.

The circadian cycle impacts sympathetic nerve activity (SNA), cardiovascular hemodynamics, and renal function. Activation of renal sensory nerves by chemosensory and mechanosensory stimuli reflexively changes efferent SNA and arterial blood pressure (ABP) to maintain homeostasis. However, it is unclear to what extent circadian cycle influences reflex SNA and ABP responses to renal sensory stimuli. Renal, splanchnic, and lumbar SNA and ABP responses to intrarenal arterial infusion of bradykinin or capsaicin and elevated renal pelvic pressure were measured in male and female Sprague-Dawley rats during nighttime (wakeful/active phase) and daytime (inactive phase). Intrarenal arterial bradykinin infusion significantly increased efferent renal SNA, splanchnic SNA, and ABP but not lumbar SNA. Responses were greater during nighttime versus daytime. Similarly, intrarenal arterial capsaicin infusion significantly increased renal SNA and splanchnic SNA, and responses were again greater during nighttime. Elevated renal pelvic pressure increased renal SNA and splanchnic SNA; however, responses did not differ between daytime and nighttime. Finally, afferent renal nerve activity responses to bradykinin were not different between daytime and nighttime. Thus, renal chemokines elicit greater sympathoexcitatory responses at nighttime that cannot be attributed to differences in afferent renal nerve activity. Collectively, these data suggest that the circadian cycle alters the excitability of central autonomic networks to alter baseline SNA and ABP as well as the magnitude of visceral reflexes.NEW & NOTEWORTHY The current study discovers that the circadian cycle influences sympathetic and hemodynamic responses to activation of renal chemosensitive sensory fibers. Sympathetic responses to intrarenal bradykinin or capsaicin infusion were exaggerated during nighttime (active period), but mechanosensitive responses to elevated renal pelvic pressure were not. Importantly, renal afferent nerve responses were not different between nighttime and daytime. These data suggest that the circadian cycle modulates sympathetic responses to visceral afferent activation.

Experimental evidence for the impact of phages on mineralization of soil-derived dissolved organic matter under different temperature regimes

Microbial mineralization of dissolved organic matter (DOM) plays an important role in regulating C and nutrient cycling. Viruses are the most abundant biological agents on Earth, but their effect on the density and activity of soil microorganisms and, consequently, on mineralization of DOM under different temperatures remains poorly understood. To assess the impact of viruses on DOM mineralization, we added soil phage concentrate (active vs. inactive phage control) to four DOM extracts containing inoculated microbial communities and incubated them at 18 °C and 23 °C for 32 days. Infection with active phages generally decreased DOM mineralization at day one and showed accelerated DOM mineralization later (especially from day 5 to 15) compared to that with the inactivated phages. Overall, phage infection increased the microbially driven CO2 release. Notably, while higher temperature increased the total CO2 release, the cumulative CO2 release induced by phage infection (difference between active phages and inactivated control) was not affected. However, higher temperatures advanced the response time of the phages but shortening its active period. Our findings suggest that bacterial predation by phages can significantly affect soil DOM mineralization. Therefore, higher temperatures may accelerate host-phage interactions and thus, the duration of C recycling.

RUSYA TÜRKLERİNDE KADIN HAKLARI MESELESİ

Türk tarihi açısından kadının sahip olduğu konum yüzyıllar boyunca mutlak surette değişikliklere uğramıştır. İslam öncesi Türk toplumlarına bakıldığı zaman kadının erkekle beraber toplumsal hayat içerisinde aktif olarak yer aldığı, kılıç kuşanıp ata bindiği ve sürekli bir şekilde talim yaptığı görülmektedir. İslamiyet’in Türk toplumuna girmesinin ardından da kadınlar sahip olduğu çoğu hakkı ilk başta korumuş fakat İslam dininin yanlış bir şekilde yorumlanması ve etkileşim içerisinde bulunulan Arap kültürünün tesiri altında kalınması sonucunda kadının statüsünde bir düşme görülerek toplumsal hayat başta olmak üzere pek çok alanda ikinci plana atılmıştır. Kadın hakları meselesi mevzu bahis olduğu zaman da tüm dünyada olduğu gibi Rusya Türkleri arasında da bu husus üzerinde hassasiyetle durularak çalışmalar yürütülmüştür. İsmail Gaspıralı öncülüğünde ortaya çıkan Usul-i Cedit hareketi doğrultusunda kızların eğitimi için tamamen onlara tahsis edilen kız okulları yenileşme çabaları içerisinde önemli bir yere sahiptir. Basının toplum üzerindeki etkisinin farkında olan İsmail Gaspıralı uzun uğraşlar sonucunda çıkarttığı Tercüman Gazetesi’nde, kadın haklarına yönelik yazılara yer vermiş olsa da bunu dönem içerisinde yeterli görmemiştir. İsmail Gaspıralı’nın imtiyaz sahibi olduğu ve kızı Şefika Gaspıralı’nın editörlüğünü üstlendiği Âlem-i Nisvân Dergisi ise Rusya Türkleri arasında çıkarılan ilk kadın dergisi olma özelliği taşımaktadır. Âlem-i Nisvân’ın açtığı bu yolda, ondan sonra Işık, Süyüm Bike, Azat Hanım ve Şark Kızı gibi birçok dergi yayınlanmıştır.
 Siyasi açıdan kadın hareketlerinin oluşumu ise Rus İhtilali’nin 1905 yılında gerçekleşmesiyle birlikte Çar’ın Rus olmayan azınlıklara kendi örgütlerini kurabilme hakkı tanıyan 1906 tarihli geçici kararnamesi ile açılan kadın cemiyetleri sayesinde mümkün olmuştur. Düzenlenen Rusya Müslümanları Kongreleri de kadınların ait olduğu toplumsal statüye ulaşabilmeleri için önem arz etmektedir. Kadınlar açısından aktif bir mücadele döneminin başladığı 1917 yılında toplanan Rusya Müslüman-Türk Kadınları Kongresi de kadınların kendileri hakkında son derece dikkat çekici kararlar aldıkları bir oluşum olarak görülmektedir. Daha sonra Rusya genelinde yaşayan tüm Türk ve Müslümanların katılımıyla gerçekleştirilen Bütün Rusya Müslümanları Kongreleri, sunulan konular sebebiyle karşılaşılan muhalefetlere rağmen Müslüman-Türk kadınının haklarını savunan aydınların mücadeleleri sonucunda kadın-erkek eşitliğinin sağlanması ve siyasi alanda kadının hak ettiği noktaya gelebilmesi için Türk Kadın Hareketine büyük katkı sağlamıştır.
 Bu çalışmada tarihi süreç içerisinde Rusya Türkleri arasında kadın ve kadın hakları meselesi ele alınacaktır. Türk Kadın Hareketine dair ilk gelişmelerin Kazan Tatarları tarafından kadınların konumunu iyileştirmeye yönelik başlamasıyla birlikte bu konuya desteğini esirgemeyen Türk aydınları ve onların yapmış oldukları faaliyetler hakkında birçok bilgi çalışmanın kapsamına girmektedir. Meselenin gidişatı açısından son derece önemli olan gazete ve dergiler kadın hareketine sunduğu katkı sebebiyle üzerinde durulan hususlar arasında yer almaktadır. Kadın cemiyetlerinin oluşumu ve düzenlenen çeşitli kongreler de incelenen konuların temelini oluşturmaktadır.

Insights into the different mixing states and formation processes of amine-containing single particles in Guangzhou, China

The formation processes of particulate amines are closely related to their emission sources and secondary reactions, which can be revealed through the investigation of their real-time mixing states in individual particles. The mixing states of methylamine (MA)-, trimethylamine (TMA)-, and diethylamine (DEA)-containing particles were studied using a high-performance single particle aerosol mass spectrometer (HP-SPAMS) in Guangzhou, China, in January 2020. The sharp increase in TMA particles was found to be closely associated with the increase in the ambient relative humidity (RH), while the MA- and DEA-containing particles were not similarly influenced by the changes in the RH. The prominent enrichment of secondary oxygenated organics in DEA particles during the daytime was consistent with the active period of photochemistry, implying that the sharp decrease in DEA particles in the afternoon was likely due to photo-oxidation of the DEA. The number fraction (Nf) of DEA particles, the Nf of the nitrate in the DEA particles, and the abundance of nitrate increased as the NOx content all increased during the nighttime, suggesting that the formation of DEA·HNO3 salt was the dominant pathway of particulate DEA production. These results are consistent with our previous measurements in Nanjing, confirming the general and distinct mixing states of TMA and DEA particles. Positive matrix factorization analysis revealed that the total fraction of the more oxidized organics factor and the less oxidized organics factor were much higher in the DEA particles (26.9 %) than in the TMA particles (9 %), confirming the significant enrichment of oxygenated species in the DEA particles. The different mixing states of the amines revealed the unique response of each type of amine to the same atmospheric environment, and the prominent mixing states of the DEA with secondary oxygenated species suggest the potential role of DEA in tracing the evolution of organic aerosols.

Fire Weather Conditions in Boreal and Polar Regions in 2002–2021

Fire activity in 288 areas (2.5° N × 10° E) in the Arctic region (50°–70° N, 0°–360° E) was analyzed using about 4.4 million satellite hotspot (HS) data from 2002 to 2021. A total of 21 high fire density areas from eastern Europe to western Canada were selected, and their fire–weather conditions during each active fire period were analyzed using about 1820 various weather maps at the upper and the lower air level. Analysis results showed that the active fires in the Arctic region occurred under the fire–weather conditions associated with the northward movement of cut-off high (COH) and warm air masses detached from the south caused by large westerly meandering (LWM). LWM is a sign of the beginning of an active fire period. Very active fires on HS peak days occurred several days after the start of the northward movement of COHs and under mainly high-pressure conditions in the upper air and strong wind conditions in the lower air. The time lag of these several days suggests that we may be prepared for very active fires. The fire–weather analysis approach described in this paper has shown that future large-scale fire outbreaks are predictable.

Voxel Based Morphometric Analysis of Regional Gray Matter Alterations Related with Duration of Illness, Number of Psychotic Episodes, Lifetime Antipsychotics Use in Patient with Schizophrenia

Objective: Schizophrenia is known to be quite a heterogeneous disorder in terms of etiological factors, clinical features and, treatment response. Changes in gray matter areas with structural imaging studies seem to be a reflection of this diversity. The relationship of duration of illness, active psychosis periods,
 and antipsychotic treatment with structural changes in the brain has not been clarified yet. The aim of our study is to investigate the effects of the disease and disease-related processes (duration of illness, antipsychotic treatment, number of the psychotic episodes) on the brain structures.
 Material and Methods: Thirty three schizophrenic patients and 35 age, gender and education matched healthy volunteers participated in our study. Life-time antipsychotic exposure determined for the patients and inverted dose/year unit over equivalent chlorpromazine doses. Magnetic resonance images were acquired with a 3 Tesla-powered imaging unit. By using Statistical Parametric Mapping 8, images were compared with voxel-based morphometry (VBM) analysis. Independent samples t-test for statistical evaluation based on the data characteristics were used. By using the general linear model (GLM) age, gender, and total brain volume were included as confounding factors in the analyze matrix in VBM. In GLM, t-test was used to compare two groups and to investigate disease process-related GM changes, multiple regression analysis were applied. In VBM, p values of less than 0.001 and areas with a minimum expected number of voxels per cluster of 50 are required.
 Results: Compared to controls, patients showed decrements in gray matter density in the right middle and inferior temporal gyrus, bilateral middle frontal gyrus, left cingulate gyrus, left precentral gyrus, left supramarginal gyrus. Nevertheless, patients showed increased GM density in the right uncus, left caudate, and left posterior cingulate cortex as compared to controls. In the patient group, duration of illness was negatively associated with GM density in the left precentral gyrus and left postcentral gyrus. The lifetime exposure to antipsychotics correlated negatively and positively with gray matter density in, respectively; left inferior frontal gyrus and right precuneus. The number of psychotic episodes was positively associated with GM density in the left medial frontal gyrus, right precentral gyrus and left paracentral lobule whereas negatively in the uvula (cerebellum).
 Conclusion: It can be said that GM deficits in schizophrenic patients are prominent in frontal and temporal areas. Besides illness duration, antipsychotic treatment, and number of psychotic episodes seem to be associated with changes in brain GM. Further studies are needed to clarify the increase in the limbic lobe GM density.

Improved mining subsidence prediction model for high water level area using machine learning and chaos theory

Ground surface monitoring (GSM) points collect information for mining surface subsidence monitoring and environmental governance. However, GSM points submerge in high groundwater mining areas, preventing the collection of monitoring data. The application of machine learning (ML) algorithms to subsidence prediction ignores the uncertainty and irregularity in subsidence changes. Thus, an innovative GSM point information prediction model, which improves the multikernel support vector machine (GA-MK-SVM) using chaos residual theory commonly used for capturing GSM point information, is proposed. The mean relative errors (MREs) between the predicted and observed results of GA-SVM and GA-MK-SVM were 8.2% and 6.1% during active periods, respectively. The GA-MK-SVM also performed better than the GA-SVM during stable periods. The residual error accumulates as the ML algorithms progress, resulting in imprecise predictions of the GSM points. Thus, the GA-MK-SVM model was improved using chaotic theory (Chaos-GA-MK-SVM), with MREs of 5.0% and 0.9% during the active and stable periods, respectively. The accuracy of the proposed model was improved by 1.1% and 3.2% compared with the unimproved GA-MK-SVM, respectively. The proposed approach provides practical GSM point information for mining subsidence studies and governance in high groundwater mines.

Controlled activation of cortical astrocytes modulates neuropathic pain-like behaviour

Chronic pain is a major public health problem that currently lacks effective treatment options. Here, a method that can modulate chronic pain-like behaviour induced by nerve injury in mice is described. By combining a transient nerve block to inhibit noxious afferent input from injured peripheral nerves, with concurrent activation of astrocytes in the somatosensory cortex (S1) by either low intensity transcranial direct current stimulation (tDCS) or via the chemogenetic DREADD system, we could reverse allodynia-like behaviour previously established by partial sciatic nerve ligation (PSL). Such activation of astrocytes initiated spine plasticity to reduce those synapses formed shortly after PSL. This reversal from allodynia-like behaviour persisted well beyond the active treatment period. Thus, our study demonstrates a robust and potentially translational approach for modulating pain, that capitalizes on the interplay between noxious afferents, sensitized central neuronal circuits, and astrocyte-activation induced synaptic plasticity.