Active Longevity Research Articles

Social exclusion of older people in rural areas during the COVID-19 pandemic in the Republic of Karelia

The article discusses the issue of social exclusion of elderly people in rural areas during the COVID-19 pandemic. The author relies on the concept that defines social exclusion as a mechanism for separating a certain group of people from an integral community. Using the example of several respondents, the article examines the effects that social exclusion of elderly people creates in rural areas, as well as possible ways of their adaptation that can minimise it. The empirical basis of the work is collected by the author 20 semi-structured interviews with elderly people living in rural areas in the Republic of Karelia and 20 diaries of their observations. When analysing interviews and diaries, a thematic method was used. The main result of the study is the identification of various fears and characteristics of the perception of social exclusion as a condition associated with changes in the habitual everyday life, as well as the lifestyle of respondents due to isolation. The main conclusion highlights the various fears presented in the perceptions of social exclusion by elderly people associated with changes in the usual everyday life due to isolation. The study also identifies the most effective ways for adaptation of elderly people to minimise their social exclusion: expanding communication with neighbours, translating communication into digital format. The data obtained by the author also allow us to draw a conclusion about changes in the sociological consideration of ageing. It becomes not a state of inclusiveness and activity, integration of elderly people into society, as modern concepts and approaches denote it (for example, the concept of active longevity), but a state that is primarily determined by physical weakness. The need for isolation, as well as limitation of activity, is becoming a forced measure that negatively affects older people and the characteristics of their perception of their age and the situation of a pandemic. This work contributes to the latest research into the understanding of ageing in the context of forced social exclusion in connection with the COVID-19 pandemic.

Prospects for the study of active longevity among researchers

Prospects for the study of active longevity among researchers

Social effect of implementing active longevity strategies

The article analyses the domestic and foreign practices of making decisions on financing projects related to demography, health, and social protection of the population. The paper considers declarations, concepts, and strategies directing to solve the problem of population aging, which is relevant for countries of the Europe, North America, the Russian Federation. The authors investigate the issues of an assessment of the social effect of implementing strategies and programs for active longevity, in domestic science and practice and conclude, that at present, universal methodology is not developed, and the existing standard approaches are adapted from the management of corporate structures. The purpose of the article is to test the system of measuring the social effect of implementing the concept of active longevity in the region. The methodological basis of the study are the factor approach, methods of analysis of time series, the factor approach, as well as recommendations of the World Health Organization (WHO), the United Nations Organization (UN) and the European Union (EU). The scientific novelty of the presented results lies in the author`s methodological developments: the interpretation of the social effect of the active longevity strategy and the system of statistical indicators for assessing the social effect in the implementation of active longevity strategies in the region. The practical significance of the results is that the regions of the Russian Federation can use the author’s system of social effect meters to monitor strategies and programs for the implementation of active longevity. The use of the system of indicators will provide a solution to the problem of its quantitative assessment, it will allow us to find out the shortcomings of regional target indicators at the planning stage and will help to increase the level of consistency of the goals of regional strategies with national goals and requirements of international organizations.

Can Blood-Circulating Factors Unveil and Delay Your Biological Aging?

According to the World Health Organization, the population of over 60 will double in the next 30 years in the developed countries, which will enforce a further raise of the retirement age and increase the burden on the healthcare system. Therefore, there is an acute issue of maintaining health and prolonging active working longevity, as well as implementation of early monitoring and prevention of premature aging and age-related disorders to avoid early disability. Traditional indicators of biological age are not always informative and often require extensive and expensive analysis. The study of blood factors is a simple and easily accessible way to assess individual health and supplement the traditional indicators of a person’s biological age with new objective criteria. With age, the processes of growth and development, tissue regeneration and repair decline; they are gradually replaced by enhanced catabolism, inflammatory cell activity, and insulin resistance. The number of senescent cells supporting the inflammatory loop rises; cellular clearance by autophagy and mitophagy slows down, resulting in mitochondrial and cellular damage and dysfunction. Monitoring of circulated blood factors not only reflects these processes, but also allows suggesting medical intervention to prevent or decelerate the development of age-related diseases. We review the age-related blood factors discussed in recent publications, as well as approaches to slowing aging for healthy and active longevity.

Statistical Estimates of the Number of Progenitors in Russian Regions

The paper explores the phenomenon of grandparen-tal labor as the activity of grandparents in relation to their grandchildren, the content of which is care, assistance to grandchildren, and their development. Methodological principles for estimating the number of actors of grandparental labor are formulated. On the basis of statistical data, the age of entry into the grandparenting is estimated, and the proportion of grandparents actively engaged in grandparental labor in the regions of Russia is calculated. The re-sults show that the involvement of women in grandparental labor is higher than that of men, and there is a positive correlation between these indica-tors; in Russia, there is a high regional differentia-tion of the involvement of grandparents in grandpa-rental labor. Creating conditions for the activation of grandparental labor in the Russian regions would increase the values of the active longevity index and get all the positive effects that arise in society when the involvement of grandparents in the life of their grandchildren increases.

Determination of technological parameters for the production of enriched flour mixtures in a drum mixer

The lack of micronutrients in the diet of the population affects the growth of alimentary-dependent diseases, affects the preservation of health and active longevity. One of the most effective methods of preventing micronutrient insufficiency is the enrichment of mass-consumption food products with vitamin and mineral premixes. Additionally, it is recommended to enrich the missing micronutrients to the level corresponding to the physiological needs of the body with mass-use products, which can include flour confectionery products, in particular cookies. The main factors shaping the quality of finished enriched products are raw materials and production technology. A special role in the application of premixes for flour products is assigned to the mixing process, because when mixing the premix with flour, its uniform distribution must occur throughout the entire volume of the mixture to obtain high-quality finished products with a guaranteed content of vitamins and minerals declared in the premix. Development of recipes and selection of technological parameters of mixing are relevant for the practical implementation of results in industrial production. For this purpose, studies have been conducted to obtain a homogeneous flour mixture consisting of wheat flour and vitamin-mineral premix on a drum mixer. The obtained data allowed us to determine the rational parameters of mixing the initial ingredients, which produce an enriched flour mixture with the specified quality indicators. The numerical values of quality indicators were processed using multiple regression methods, on the basis of which a regression model was obtained describing the quality of a flour-enriched mixture (with a high degree of accuracy) depending on the technological parameters of mixing a drum mixer.

A new understanding of health and a healthy lifestyle: a holistic and existential-humanistic approach

Confronting current challenges, especially the COVID-19 pandemic, and striving to create a hopeful future – an era of life and active longevity – determine an urgent global need to implement the principles of humanity and create a new understanding of health and a healthy lifestyle, correlated with a fundamental respect for the dignity of life. Based on the idea of the relationship between health and a healthy lifestyle through the inherent value of the individual, embodying the intrinsic value of life, basic contradictions were identified: the contradiction between the understanding of health as a state of physical, mental, and social well-being and a healthy lifestyle, which focuses on the physical aspect of health, omitting the spiritual component; the contradiction between the numerous proposed strategies for a healthy lifestyle and the lack of a fundamental goal that expresses its value-semantic result. In the aspect of philosophical-methodological ideas about health and a healthy lifestyle, their essential binding element was defined – the good that embodies the result of the ultimate aspiration of a person. The resolution of the basic contradictions revealed in the analysis of philosophical-methodological ideas about health and a healthy lifestyle made it possible to present new, clearer definitions of health and a healthy lifestyle: health is a good that allows a person to embody the value of life in a specific reality; a healthy lifestyle is an individual way of life, which is based on a person’s respect for the dignity of life and creates a benefit to him/herself and others, gaining the joy of existence. A new concept of a healthy lifestyle was developed, which defined the joy of existence as its fundamental goal, implemented by a person through the creation of good for oneself and others in a system of socio-cultural and natural interaction based on respect for the dignity of life.

A CLINICAL STUDY TO EVALUATE THE RASAYANA EFFECT OF ASTHISHRINKHALAGHRITA IN JARA

Modern medicine has made a great deal of progress in understanding the aging process and in controlling age-associated health issues. The problems of Aged were neglected by Ayurvedic science and recently there started new advancements in this branch of Ayurveda which is insufficient for the current needs. This had led to lack of active longevity with more disability and dependency. Thus, this study was taken up to evaluate the Rasayana (Anti- ageing) effect of Asthishrinkhalaghrita in Jara janya vyadhi (Diseases due to senility). Methods: In present study, 30 subjects were diagnosed with the Jara janya vyadhi, selected randomly and were given with 15 ml of Asthishrinkhalaghrita in the morning for 30 days. The data obtained were recorded, tabulated and statistically analyzed using appropriate statistical methods. Results: Study showed mild improvement in overall treatment. Though no statistically significant results were obtained, there was a good improvement for the patient in Climbing stairs, Sleep disturbance, Shwasa vridhi (Dyspnoea), Malabadhata (Constipation), Agni mandya (loss of appetite)and weight gain with p value<0.05 and Slatha sandhi (laxity of joints)and walking with p value > 0.05. Conclusion: Thus Rasayana chikitsa can improve the longevity, positive health; provide the resistance to fight against the diseases, keeping the excellence in the tissues including mental faculties.

Tracing the past from the analysis of Cu, Zn, Mn, Sr, and Rb in Archaeological Dark Earth soils from the tropics and temperate zone

The analysis of minor/microelements in anthropogenic soils resulting from past settlement activities in different environmental conditions and geographical regions is not well-known. The study aimed to determine whether minor/microelements are suitable proxy indicators of past human activities of Archaeological Dark Earth (ADE) soils from two past hilltop settlements- Ziavi-Galenkuito in Ghana and Dřevíč hillfort, Czech Republic. Total and plant-available (Mehlich 3) contents of minor/microelements were determined using portable X-Ray Fluorescence spectrometry and Inductively coupled plasma mass spectrometry, respectively. The black color of the soils from Ziavi-Galenkuito and Dřevíč hillfort contrasted the brownish Ferric Acrisol and greyish Luvic Cambisol control, respectively. The contents of total and plant-available Cu, Zn, Mn, Sr, and total Rb was substantially higher in both sites compared to their control of the same geological substrates. The highest total and plant-available Mn content in Ziavi-Galenkuito may indicate specific intensive settlement activities in a comparatively shorter duration. The highest total Cu, Zn, Sr, and Rb content in the soil from Dřevíč hillfort compared to Ziavi-Galenkuito related to longevity and intensity of the past human activities. Total Cu, Zn, Mn, and Sr can well reflect past human activities from different geographical regions according to their significant correlations from both studied sites. Except for Mn and Sr, total and plant-available content of Cu and Zn were not well correlated. Except for Mn and Sr, total and plant-available content of Cu and Zn were not well correlated. In the calculation of enrichment factors in ADE soils for geoarchaeological purposes, total Mn, Cu, Zn, and Sr are more suitable. Enrichment by minor/microelements can be reliable enough in predicting past human activities in ADE soils of different geology and climatic conditions, even after hundreds of years.

Normativity and the Aging Self: “Active Longevity” Media Discourse in Contemporary Russia

This article explores the normative understandings of older adults, old age, and aging as they are articulated in the mainstream media’s discourse on “successful aging” and “active longevity” in contemporary Russia. I draw on critical gerontological approach and critical discourse analysis to examine the articles published in 2016–2018 in one of the most popular Russian weekly newspapers, Argumenty i Fakty (Arguments and Facts), which actively engages in discussions of “activity,” “longevity,” and “success” in later life. This article traces the consumerist logic behind the “successful aging” discourse, which takes the notion of “success” as a matter of lifestyle that can be maintained through individual’s voluntary reflexive participation in consumerist practices and, thus, ignores the social-structural factors affecting this process. The aging subject is invited to engage with the “successful aging” ideal and express their “reflexive” self through the practices of “managing” health and longevity, appearance and embodiment, and manifestations of sexuality. However, this “successful” management suggests a correlation with the conventional perceptions of femininity, masculinity, and sexuality, subjectivity buttressed with neoliberal values, and familial life in which the aging subject must remain a resource for younger generations. This analysis indicates that such standards exclude those life trajectories that do not comply with the norms of the discourses on aging in an “active” and “successful” way. Article in English DOI: 10.25285/2078-1938-2020-12-2-45-67

ПИТАННЯ РЕАЛІЗАЦІЇ РЕСУРСНОГО ПОТЕНЦІАЛУ ЛЮДЕЙ ПОХИЛОГО ВІКУ В СФЕРІ ОСВІТИ

In the context of accelerating the demographic aging of Russia and raising the retirement age in the country, the issues of active longevity and the realization of the resource potential of older people in various fields are significantly updated. The purpose of the article is to assess the implementation of active longevity in the field of education. The object of the study is the population of the retirement age of the Komi Republic. Methods used in the study. The study used methods of systemic, statistical analysis, comparison, induction and financial and economic analysis. The main hypothesis of the study was the assumption that the use of the resource potential of older people will improve the quality of education with a view to the sustainable development of the state economy. Statement of the main material. The study was carried out on the basis of official statistics and the results of sociological surveys of the population over 55 years old, conducted in 2013 and 2018. The article discusses the dynamics of the level of professional education of the population over working age in Russia and the Komi Republic, assesses the attitude of older people to new knowledge and their real willingness to learn as the most important components of the resource potential of older generations. The originality and practical value of the study. It was established that almost half of Russian pensioners are highly qualified specialists with secondary and higher professional education, in Komi their educational level is somewhat shifted in favor of secondary professional education, which is due to the characteristics of the sectoral structure of the economy. The level of education of older people continues to grow and is gradually approaching the level characteristic of working age. At the same time, the older generation has significant cognitive potential, which is characterized by growth. More than 60% of older people surveyed in 2018 believe that older people are able to acquire new knowledge and skills, and 40% are ready to retrain themselves. Conclusions. In the context of the growing economic challenges of demographic aging, it is necessary to expand the possibilities of realizing the resource potential of the older population, not only in employment, but also in education

Elderly families of indigenous peoples of the Arctic in the sociological dimension

The increasing share of older people in the demographic structure of society, the increasing instability of family and marriage relations, the transformation of the traditional family model in the context of global social and natural changes – this is not a complete list of factors that affect the institution of the family. The phenomenon of old age, including the elderly family, is a complex ideological problem of the value of life.Demographic aging requires a special infrastructure focused on meeting the social needs of people over 65 years of age. Such modernizations primarily concern the sphere of health and social services. Together with various types of social services, conditions are created that ensure the active longevity of elderly citizens. Family development is based on the social and personal needs of a person. In modern Russia, there is instability and transformation of family relations, which, in our opinion, is an indicator of crisis phenomena in its development, as well as institutional changes. Statistics for 2018 in Russia show that 65 % of marriage relationships have broken up, whereas 70 years ago, divorce was rare. And the forecast is quite negative, under such circumstances, there will be more and more divorces every year. And all the more valuable is the role of families who have a long family history and life experience. Their accumulated family values, proven over time, can help strengthen the institution of the family, preserve its significance for society and the individual, especially in the harsh conditions of life in the Arctic, when mutual assistance and mutual support becomes even more meaningful for a person.

Состав и регламентируемые показатели качества карамели функциональной направленности

Introduction. Functional foods help to improve the diet, maintain health, and prolong active longevity. Therefore, food science constantly develops new formulations of functional products. Caramel can hardly be called healthy food as it possesses low nutritional and high energy value. Moreover, caramel contains easily digested sugars but no physiologically functional ingredients, e.g. vitamins, minerals, etc. In order to increase the nutritional value of caramel, we fortified the traditional formulation with ascorbic acid and Valetek-3 vitamin premix. 
 Study objets and methods. The research featured laboratory and pilot samples of caramel. The quality indicators of the finished product were determined according to the industry standards. 
 Results and discussion. The research provided advanced formulations and technology for the development of the new functional caramel fortified with ascorbic acid and a vitamin complex. A set of experiments resulted in a nomenclature of regulated quality indicators and functional properties. The changes in the quality of the caramel during storage made it possible to define the shelf-life of the product. 
 Conclusion. The research defined the optimal formulation for the new kind of functional caramel and determined its quality indicators. The present article introduces a list of quality standards for caramel fortified with vitamin C (ascorbic acid) and Vitalek-3 vitamin premix, as well as the indicators of its functional properties. The research provided the new functional food with the regulatory and technical documentation necessary for its mass production.

Availability of balanced nutrition at the level of scientific basis for norms of all layers of the population of Ukraine

The basis of all life processes of the human body is a constant metabolism between the body and the environment. From the environment, people consume oxygen, water and food. The role of food is to replenish energy and tissue elements necessary for growth, development and functioning of the body, ensuring metabolic processes, normal health and efficiency. Rational nutrition (ratio – reasonable) is a physiologically complete nutrition of healthy people taking into account their age, sex, nature of work and other factors. Nutritional nutrition contributes to maintaining good health, resistance to harmful environmental factors, high physical and mental capacity, as well as active longevity. The article is devoted to the issues of accessibility to a balanced diet at the level of scientifically substantiated norms of the population of Ukraine. The main problems of mankind are covered, such as: poverty, hunger, malnutrition and food security, etc. Based on statistics for the last few years, the article has calculated and reflected such indicators as: the level of poverty in Ukraine according to national accounts and the upper poverty level of $ 5.50. US per day according to the World Bank, %, the dynamics of indicators of meat consumption in Ukraine, the compliance of indicators of meat consumption in Ukraine with rational standards, etc. The importance of solving problematic issues of food security, which affects the level of socio-economic development of society and countries in general, the ratio of production, consumption and demand for sugar and oil in Ukraine, the prevalence of malnutrition in children and adults in Ukraine, the ratio of nutrition standards in secondary schools for one-time nutrition of students and the physiological needs of the population of Ukraine in basic nutrients and energy. The concept of rational nutrition is revealed. The state of food security determines, in particular, the level of food security, is the key to socio-economic development of society. For the world agricultural system there is a growing trend in declining inventories, rising prices, increasing differences in the level of agricultural development in countries with economic crises and globalization. The availability of a balanced diet at the level of scientifically sound standards for all segments of the population is also considered, which today is one of the main challenges of our time, which gives our study importance and significance.

Protective effect of quercetin in combination with caloric restriction against oxidative stress-induced cell death of Saccharomyces cerevisiae cells.

Impairment of antioxidant enzymes activities has been well reported in several human diseases. Effective anti-ageing strategies involving antioxidant supplementation and/or caloric restriction (CR) are receiving a great attention to mitigate free radical-mediated oxidative damage in several disease conditions to improve active longevity. Therefore, in this work, we have evaluated the protective effect of quercetin under non restriction (NR) and CR conditions on the sensitivity of Saccharomyces cerevisiae mutant strains (sod1∆, sod2∆, cta1∆, ctt1∆, tsa1∆ and glr1∆) deficient in antioxidant defence systems (superoxide dismutase, catalase, thioredoxin peroxidase and glutathione reductase) against H2 O2 -induced oxidative stress. Our results demonstrate that quercetin in combination with CR has strongly reduced the H2 O2 -mediated stress in the yeast mutant cells compared to NR conditions. Furthermore, we show that quercetin in combination with CR enhanced the percentage viability of yeast cells during chronological ageing. Our research findings suggest that antioxidant supplementation in combination with CR might have potent beneficial effects than individual therapies against free radical-mediated oxidative stress. SIGNIFICANCE AND IMPACT OF THE STUDY: Oxidative stress results from an imbalance between free radicals and antioxidant defense systems in our body. Supplementation with exogenous antioxidants is necessary to neutralize the free radical mediated damage. Polyphenols are a group of naturally occurring plant compounds with strong free radical-scavenging activity and exhibits potent anti-aging property by mitigating oxidative stress. On the other hand, caloric restriction (CR) has been reported to be a popular leading anti-aging approach to ameliorate age-associate macromolecular damages in various chronic human diseases. Evaluation of protective effects of antioxidant supplementation in combination with CR against free radical mediated oxidative stress is pivotal for the development of novel anti-aging strategies to improve active longevity.

J1110+4817 – a compact symmetric object candidate revisited

ABSTRACT Compact symmetric objects (CSOs) are radio-emitting active galactic nuclei (AGNs) typically with a double-lobed radio structure confined to within 1 kpc. CSOs represent the earliest evolutionary phase of jetted AGNs. Some of them may eventually evolve into large-scale extended double sources, while others stall within the host galaxy and die out, depending on the longevity of nuclear activity, the jet power, and parameters of the surrounding galactic environment. Studying CSOs is a useful tool for understanding the evolution of the galaxies and the interactions between the jets and the medium of the host galaxy. Based on milliarcsec-resolution imaging observations using very long baseline interferometry (VLBI), it is not always straightforward to distinguish between a compact double-lobed or a core–jet structure. The quasar J1110+4817 was considered a CSO candidate in the literature earlier, but because of the lack of clear evidence, it could not be securely classified as a CSO. Here we present a comprehensive analysis of archival multifrequency VLBI observations combined with accurate Gaia optical astrometric information. Lower frequency VLBI images reveal an extended radio feature nearly perpendicular to the main structural axis of the source, apparently emanating from the brighter northern feature, which is rare among the known CSOs. While the presence of a binary AGN system cannot be fully excluded, the most plausible explanation is that J1110+4817 is a CSO.

Quality of life and cardiovascular risk in women during menopausal transition and postmenopause

The task of active longevity is a priority for world and national health care. One of the resources to ensure the quality of life for aging women is the rationalization of nutrition using biologically active additives (BAA), which include substances that have proven effective in stopping the symptoms that accompany the menopausal transition and early postmenopause. Given the association of vasomotor symptoms with an increased risk of cardiovascular disease, it can be assumed that solving the problem of improving the quality of life will positively affect cardiovascular risk. Based on this hypothesis, we set the goal of the study to assess the effect of dietary supplements containing phytoestrogens on the quality of life and markers of cardiovascular risk in women during menopausal transition and postmenopause. An open, controlled study involved women aged 46–58 years who took Estrovel dietary supplement or a vitamin complex without herbal supplements, examined using questionnaires to determine the severity of menopausal complaints, assess mental status, vegetative support, as well as monitor blood pressure, and samples for vegetative providing, analysis of heart rate variability. The results of the study showed that women taking Estrovel dietary supplement to improve the quality of life, in addition to stopping the symptoms of pathological menopause, receive additional benefits in the form of improved psycho-vegetative status and markers of cardiovascular risk with high safety and good tolerance of the method.

Restoring adaptive potential and active longevity using ginseng phytomicrospheres

Medicines with adaptogenic activity, containing ginseng extractive substances as an active ingredient are widely used in pharmacology. Biologically active products obtained using innovative technology using Phytomicrospheres® are relevant in strategies for increasing adaptation, overcoming chronic stress, anti-age. The article presents an analysis of the effectiveness of the use of a plant complex based on the active ingredients of the ginseng plant, using phytomicrosphering technology, which ensures maximum assimilation of all components by the body. Having a high bioavailability, the complex has a beneficial effect on the cardiovascular system, improves blood circulation, stimulates the supply of oxygen to brain tissue, prevents premature aging, improves performance and intellectual activity, and improves memory and concentration.

Vitamin D as a factor for improving the quality of life in women after 50 years (literature review)

Relevance. Public health is one of the key factors in the development of the economy and at the same time an objective indicator of quality of life. Currently, the number of women over 50 years old is progressively increasing, and their growing social inclusion will determine the desire for active and healthy longevity. In this regard, the public health policy in the country should follow the path of increasingly large-scale financing of projects of a healthy lifestyle, not concentrating expenses only on medical care.
 Aim. Analysis of literature on the feasibility of using vitamin D as a factor that improves the quality of life of women in the perimenopausal period and in menopause.
 Materials and methods. To write this review, we searched for domestic and foreign publications in Russian and international search engines (PubMed, eLIBRARY, etc.) over the past 20 years. The review included articles from peer-reviewed literature.
 Results. The review outlines a wide range of biological properties of vitamin D involved in the regulation of many important physiological functions. The negative effect of vitamin D deficiency is presented not only on the development of cancer, cardiovascular diseases, but also on the increase in the severity of menopausal syndrome. It has been established that the use of colecalciferol (vitamin D3) in combination with menopausal hormone therapy contributes to the normalization of carbohydrate, lipid and calcium phosphorus metabolism, improves the neuropsychic state of patients, which makes it possible to actively use colecalciferol in routine clinical practice in menopausal syndrome.
 Conclusions. Numerous positive effects of colecalciferol (vitamin D3) allow the use of the drug as a means to increase social adaptation, and, consequently, improve the quality of life.

Features of the early diagnosis of respiratory diseases in interns of chemical industries

In the conditions of increasing retirement age and active longevity, it is especially important to maintain health of older workers employed in hazardous industries. Physiological changes occur in the body, including respiratory system, with aging, they are modified under conditions of exposure to chemicals and in the post-exposure period. Incidence rate of temporary disability in the Perm Krai amounted to 45.0 cases per 100 employees. The average regional indicator was exceeded more than twice in chemical enterprises; respiratory diseases predominated in the structure of causes of temporary disability both in the number of cases and the number of days of disability, with an average duration of one case of the disease of 8.3 days. The proportion of diseases caused by industrial aerosols and chemical factors amounted to 25% in 2017 (Russian Federation 2017 - 22.35%), in 2018 - 30%. Share of respiratory diseases in the structure of nosological forms of occupational diseases has increased over the past 10 years, in 2018 it occupied the second place with 25%.