Various harmful gas emissions are a major controversial issue globally, and open dumpsites have become a leading contributor to atmospheric pollution. The study aims to introduce a high-performance landfill gas purification substrate using laterite soil, an iron, and aluminum-rich, highly available soil type in tropical countries; the final suggested substrate contained uniformly mixed laterite soil and compost with a 4:1 fraction by volume. A self-design setup that can maintain moisture content and aerobic conditions was used with an active landfill gas collection system through the gas wells established on the Karadiyana landfill in Sri Lanka under a tropical climate. The elimination capacity of CH4, NH3, VOCs, and H2S were 202860 ± 51595, 91 ± 30, 75 ± 27, and 6 ± 3 mg m−3 h−1 with 91 ± 3, 96 ± 1, 93 ± 3 and 83 ± 4% of removal efficiencies respectively at a 9.4 min empty bed residence time (EBRT). Selected laterite soil acts as an adsorption material and provides a better bio-filtering substrate with compost due to its specific characteristics. The hybrid gas purification process, absorption, and biofiltration within the proposed material were the reasons for higher performance, and the setup may be successful under the industrial waste gas streams. Further investigation should be carried out to study the medium's effectiveness as the covering layer on the dump with the successful lowest thickness, regarding secondary pollutants, and industrial applicability under unique specific conditions.