Activity Of Structures Research Articles

Modelos cognitivos de emoções musicais: abordagens discreta e dimensional

Emotions are biological, chemical, and neural reactions to stimuli, influenced by crucial brain mechanisms for human survival and well-being. Music is linked to the induction of emotions with neurobiological foundations associated with the activation of structures in the limbic and paralimbic systems. The induction of emotions is also related to specific features of mu-sical stimuli. This article aims to discuss the discrete and dimensional approaches to emotions and cognitive models of musical emotions through a literature review. The discrete approach argues that certain emotional categories are universal and innate, reflecting internally trig-gered states driven by genetically programmed bodily changes. The dimensional approach involves models that represent emotions in a few dimensions rather than specific emotional states. Both guide models of musical emotions and enable testing hypotheses and creating emotional assessment tools with music.

The right to peace in the paradigm of collective and individual subjects: dualism of approaches

The article analyzes the evolution of the right to peace from its individual status (individual rights) to collective (community rights). It is argued that it is the mass violation of human rights in the conditions of military operations against a large number of people that causes the appearance of their collective right to peace as a derivative of the individual right to life. It is noted that with the development of civilization, the individual right to life was transformed into a collective right to peace. Only at a certain stage of human development did the individual right to life undergo its transformation into the right to peace. It is about recent history, when the abstract ideas of the right to peace acquired their realizationin the respective ones international agreements and underwent their institutionalization in the activities of structures that had an international character. Attention is drawn to the fact that the right to peace as a scientific problem was problematized in the context of collective law in the 70s of the 20th century. Specifically, this period is associated with numerous scientific discussions regarding third-generation human rights, which include collective rights, in particular, the right to peace. There are six types of collective rights. This is the right to political, economic, social and cultural selfdetermination; the right to participate in and receive profits from the «common heritage of mankind»; the right to peace; the right to a healthy and balanced environment and the right to humanitarian assistance in the event of various disasters. In the context of the above, existing approaches in the scientific literature regarding the subject structure of this right are analyzed. According to the author, the right to peace belongs to both collective and individual rights. It is emphasized that the right to peace in the 21st century is a general means of ensuring the realization of all other human rights. Key words: the right to peace, individual rights, collective rights.

Elimination of structural and tree infestations of the Asian subterranean termite, Coptotermes gestroi (Wasmann) (Blattodea: Rhinotermitidae) with noviflumuron baits in above-ground stations.

The traditional stake survey and in-ground (IG) monitoring stations have been ineffective in aggregating the Asian subterranean termite, Coptotermes gestroi (Wasmann) in southeastern Florida. In this study, we used both IG and above-ground (AG) Sentricon stations to monitor and bait C. gestroi, and as expected, none of the 83 IG stations was intercepted. Despite this, AG bait stations with 0.5% noviflumuron were successfully used to eliminate C. gestroi colonies. From 2 field experiments, the mean colony elimination time (±SD) using AG baits were 6.4 ± 3.8 wk (n = 4) and 8.0 ± 2.1 wk (n = 12), respectively. Such results were compatible with baiting studies against field colonies of C. gestroi elsewhere, that is, 4-9 wk. The successful rates in monitoring and baiting of C. gestroi with IG stations in other regions also varied, which may be due to the variabilities in tunnel geometry of this species in different environments. In areas with established C. gestroi populations, routine inspection for signs of activity in structures and surrounding trees can be a critical component for pest control providers for early detection of infestation and colony elimination with AG bait stations.

УПРАВЛЕНИЕ ИННОВАЦИЯМИ В ПРЕДПРИНИМАТЕЛЬСКОЙ ДЕЯТЕЛЬНОСТИ

The innovative activity of entrepreneurial structures in Russia does not meet the requirements of the modern level of scientific and technological progress. One of the reasons for this appearance is an unfavorable economic climate, characterized by the underdevelopment of the institutional and infrastructure environment, market conditions and business conditions, the need for knowledge and technology from the business community, and the creativity of the pre-resiners. At the same time, for modern domestic entrepreneurship, the characters are weak with the main contingent of its stakeholders, which is why the consideration of the requirements and capabilities of the main part of potential partners is difficult. The proposed al-city development of the strategy and tactics of innovation in entrepreneurship will eliminate identified flaws. The subject is the socio-economic processes and relations that arise in the process of managing innovation in entrepreneurial activity. The direction of the study is the definition and methodological justification of the approach to the development of an innovation management policy in entrepreneurial activity in the context of an unfavorable innovative climate based on a stakeholder approach. The purpose of the study is to justify the influence of the innovative climate and accounting for the interests of the main stakeholders on innovative activity and innovative policy of entrepreneurial structures. Development of an algorithm for the formation of an innovative strategy and tactics of the company. In the process of research, general scientific (analysis and synthesis, induction and deduction, analogy, generalization) and special (monographic, statistical-economic, abstract-logical) methods of scientific knowledge were used. Based on the analysis of the innovative climate formed in the conditions of the formation of Industry 4.0, the need to take into account its key parameters in the development of strategy and tactics for managing innovation in entrepreneurial activity is substantiated. The influence of relationships with internal and external stakeholders on the activity and success of innovative processes in business structures has been clarified. The algorithm for developing a strategy and tactics for managing innovations in entrepreneurship has been developed and substantiated. Promising mechanisms for the activation of innovative activity in internal development are substantiated. The results of the study can be used by the legislative and executive state authorities, the academic community in the development of areas of improving the innovative climate, as well as business entities for the development and development of internal policy of innovation management.

ОЦІНЮВАННЯ ТА АНАЛІЗУВАННЯ ЧИННИКІВ, ЯКІ ВПЛИВАЮТЬ НА ФОРМУВАННЯ СИСТЕМИ МОНІТОРИНГУ ДІЯЛЬНОСТІ БІЗНЕС-СТРУКТУР

The article assesses and analyzes the factors influencing the formation of a system for monitoring the activities of business structure. We used an expert study, which allowed us to determine the factors that form the systems for monitoring the activities of business structures, and later assessed their relative importance. To take into account the factors influencing the formation of a system for monitoring the activities of business structures, cluster analysis was applied, and the isomorphic and isotonic similarity of a set of highlighted factors was used. The average scores assigned by experts for each factor are determined. Direct and indirect connections between the factors and between the clusters themselves have been identified. Specifications are used for this of KLAST_IZOMORF_TREK and KLAST_IZOTON_TREK for Microsoft Office Excel. An integrated model of relationships between the factors influencing the formation of a system for monitoring the activities of business structures, which are linearly and indirectly related to each other, has been built. The classification of factors influencing the formation of a system for monitoring the activities of business structures has been carried out. The proposed classification can be practically applied by the heads of business structures when analyzing the quality of monitoring and making corrective decisions on the selection of types of information and sources of their receipt, monitoring methods, as well as the selection of personnel responsible for monitoring. A mechanism is proposed for a set of measures aimed at using reserves to improve the quality of monitoring the activities of a business structure. It is proved that the introduction of a set of measures aimed at using reserves to improve the quality of monitoring the activities of business structures would allow the monitoring system to focus the analytical potential of managers on problematic aspects of the development of a business structure, the causes of which lie in their external environment. It is necessary to achieve such quality of monitoring, in which the nature of the action of the selected factors on the object under study is positive by default.

Изучение функциональной коннективности головного мозга для разработки лечебно-профилактических стратегий у пациентов с асимптомным каротидным атеросклеротическим стенозом

The aim of the study was to investigate the condition of the connectome in patients with asymptomatic carotid atherosclerotic stenosis of more than 60% when using hirudotherapy. Materials and research methods. The examination results of 15 patients aged 60 to 82 years with asymptomatic carotid atherosclerotic stenosis in the range of 60-75% were analyzed. The patients underwent a course of hirudotherapy of 10 sessions. All patients underwent structural and functional magnetic resonance imaging with statistical data analysis at rest, complaints and neurological status were evaluated before and after hirudotherapy course. Results of the study and their analysis. Within the course of hirudotherapy in patients with asymptomatic carotid atherosclerotic stenosis when analyzing the neurological status and complaints, a significant improvement of well-being was noted. Functional magnetic resonance imaging identified differences in functional connectivity between medial prefrontal cortex and other brain regions. There was activation in the main structures of the network of controlling and revealing significance. The connectivity between the leading areas of the brain increased, which is a sign of the improvement of the brain activity. Conclusion. The study of connectivity can serve for exploring the work of brain networks and for determining the effectiveness of therapy. A course of hirudotherapy significantly changed the functional connectivity of brain areas, the changes correlated with a decrease in the number of complaints. Such work is a pilot and will be continued in order to further develop treatment and prevention strategies with the inclusion of hirudotherapy in patients with high risk of vascular accidents in sanatorium-resort treatment.

Сетевые платформы впечатлений в экологических вопросах и организации региональной рыбохозяйственной деятельности

The article generalizes the parameters of the dynamics and the relationship of expenditures under financing from the federal budget for the conservation of aquatic biological resources and the production of commercial aquaculture products. The expenses on conservation of the aquatic bioresources and development of aquaculture under Protection and Control subprogram for the past years and appointments until 2024 are considered. Feedback on services and impressions of the products of the enterprises of the Fisheries Complex are studied on the Internet resources. The complex of various organizational and methodological works of improving the environmental safety and developing the environmental standards of fisheries management is considered. There are shown the results of responses in the Yandex search system to the requests on protection of fish stocks and ecological reproduction of aquatic biological resources. The experience of the research and analytical network products in the field of fisheries management is considered. It is emphasized that by summarizing the information of online representative offices, websites and forums it is possible to attract potential customers and consumers of seafood. The Yandex search system has analyzed the requests on organizing the trade of fish products with responses and results of functioning the relevant sites per month. A case of generalizing the staff reviews in social networks about working conditions at fishery enterprises is demonstrated. The conclusion about the growing expenses of business structures on ecological reproduction is substantiated. It is stated that in the conditions of digital economy the opinions and feedback as important factors of economic development are acquiring a new meaning in the activities of the fisheries complex. The importance of taking into account the feedback and opinions on network platforms to improve the activities of business structures in the fish industry is emphasized.

ВЛИЯНИЕ ФАКТОРА ВЗАИМОДЕЙСТВИЯ ЦИВИЛИЗАЦИЙ НА СОТРУДНИЧЕСТВО ГОСУДАРСТВ В СФЕРЕ МЕЖДУНАРОДНОГО ПРАВА

The article reveals the essence of the civilizational approach to the application of the most important institutions of international law. It analyzes the problems of interaction between European and East Asian civilizations and international law. The peculiarity of the civilizational approach to the assessment of the main institutions of international law is shown. The author evaluates the practice of applying the most important institutions of international law in the states of European and East Asian civilizations. Conclusions are drawn about the differences in the use of certain institutions and in the activities of some institutional structures. The positive qualities of these procedures for the perception of other states, in particular, Russia, are highlighted.

НЕРВНЫЕ И ГУМОРАЛЬНЫЕ ПУТИ ВЛИЯНИЯ ЭНДОТОКСИНОВ КИШКИ НА ИНТЕРОЦЕПТИВНЫЕ РЕФЛЕКТОРНЫЕ РЕАКЦИИ

In acute experiments on rats, an increase and decrease in afferent activity in the mesenteric nerves of the intestine as well as vagus under the diaphragm, depending on the site of lipopolysaccharide (LPS, 10 μg) injection into the intestinal lumen, has been established. In addition, the effect of endotoxin on the gastrointestinal tract (GIT) is manifested in a reflex change in the efferent nerve impulses. The reactions of the cervical sympathetic, splenic, cranial and caudal mesenteric nerves as well as vagus under the diaphragm are represented by an increase or decrease in the spontaneous activity of efferent fibers and depend on the zone of LPS infusion in the GIT. In general, inhibitory responses to endotoxin predominate, especially in the mesenteric nerves. According to experiments, the reflex responses of sympathetic efferent fibers caused by balloon distension of the colon are regularly weakened or completely suppressed after the infusion of LPS into the lumen of this organ. Under conditions of complete external decentralization of the GIT by transection of the vagus, all mesenteric nerves and the colon at the border with the rectum, the effects of modulation of the activity of both peripheral and central nervous structures under the influence of LPS are preserved due to the humoral pathway included in the complex neurotransmitter mechanism for controlling autonomic functions.

ВИЗНАЧЕННЯ ЦІЛЕЙ СИСТЕМИ МОНІТОРИНГУ ДІЯЛЬНОСТІ БІЗНЕС-СТРУКТУРИ

The article reveals and substantiates the theoretical aspects of determining the objectives of the system of monitoring the activities of business structures. It is established that the formation of the system of monitoring the activities of business structures begins with setting goals for monitoring. It is proved that the problematic aspect of building a universal classification of goals of business structures is: differences in business structures by their purpose and subordinate relations within the structure, as well as industry specifics. Consider the business structures that are created in Ukraine, most of them are unique in terms of structural components, industry affiliation and even strategic importance at the level of the national economy. The algorithm of realization of the purposes of system of monitoring of activity of business structure is constructed. It is proposed to take as initial data for the construction of the monitoring system not the content of the set goals (expansion of markets, growth of market value of assets, increase of profit, ensuring financial stability, etc.), but their hierarchy and causality. This approach will make it possible to develop universal recommendations for the formation of a system for monitoring the activities of business structures. The classification of the purposes of business structures is offered and proved. In the proposed classification, the types of goals are interrelated on various grounds, and together constitute a holistic system. Two goal cubes are constructed to facilitate the logic of the connections. The given goals of the business structure in terms of scale and level of coverage are a set of sets that form a boulevard. Within a specific business structure, a process model is presented, which can be detailed and developed in the direction of reflecting the specifics of the objectives of structural components, as well as industry characteristics.

Participation of NKVD and Prosecutor’s Office in Ensuring Construction of Kuibyshev Defensive Line (November 1941 — January 1942)

The article discusses the activities of the NKVD and the prosecutor’s office to ensure the mobilization and suppression of desertions from the construction of the Kuibyshev defensive line. The relevance of the study is due to the fact that the experience of the activities of the NKVD structures and the prosecutor’s office, aimed at ensuring defensive construction in the extreme realities of military operations, is an indispensable source for military engineers of the Russian Federation. Based on the introduction into scientific circulation of previously secret archival documents from the funds of RGASPI, SOGASPI and GANI UO, they paid attention to the process of building a defensive line, the situation of the mobilized and analyzed the problems of the activities of the NKVD and the prosecutor’s office. It was revealed that the employees of the internal affairs bodies and the prosecutor’s office, in order to prevent desertions, first of all sought to normalize the supply of workers with food, clothing and equipment, the establishment of exact production standards, based on the gender and age characteristics of the builders. In the course of the work, it was proved that by mid-December 1941 the repressive policy had been curtailed, and local authorities took measures to improve the food supply for workers.

Long-term factors and trends in the development of the fuel and energy complex of Ukraine

The objective of the paper is to define long-term trends and factors in the development of the world energy industry and their refraction to Ukrainian realities. The article consists of an introduction, three sections, namely: the main trends in the development of the global fuel and energy complex, analysis of the current state, long-term trends and factors in the development of the national fuel and energy complex of Ukraine. Conclusions end the paper. As for the world energy sector it is shown that its modern changes – Grand Transit – are due to the ideology of sustainable development and have the character of an extraordinary change in the technocenosis, the transition from the use of fossil fuels to energy from renewable sources, mainly – wind and photovoltaic nature. Along with the major tendencies of the Great Transition, there is also the trilemization and politicization of energy sector. Trilemization components are: Energy Security, Energy Equity and Environmental Sustainability. There are three scenarios for the development of the global energy – Unfinished Symphony, Modern Jazz and Hardrock, distinguished by the degree of greening and the availability of energy resources. Political motives are becoming more and more significant at all levels – from global to local. Major players are lobbying their interests, there is an activity of structures from the field of nuclear energy, powerful fuel companies, owners of gas transportation and gas distribution infrastructure. In Ukraine, transformation processes are taking place against the backdrop of low environmental acceptability and high depreciation of fuel and energy sector facilities and infrastructure, political and economic instability. The requirements of decarbonization create challenges to the very existence of coal energy, which is the main component of the energy generating fund of the country and the regions, where mines are located. Options for the development of hydrogen/ammonia energy in the form of vertically integrated energy-chemical systems with the nuclear power plants and reformed coal-fired thermal power plants are considered as promising; energy diversification of mining regions; the creation of virtual power plants based on hydrodynamic water heating installations.

Methodology for assessing the logistics potential of a commercial enterprise

The article is devoted to the issues and problems of the significance of the logistics potential in the activities of commercial structures. The paper considers the views of various scientists on the logistics potential from the point of view on the theory and practice of logistics. The methodological tools of the study are based on the analysis of information sources that consider this problem, as well as approaches to assessing the logistics potential. This allowed the authors to propose a methodical approach to assessing the logistics potential based on the inclusion on which the indicator value depends.

КОРПОРАТИВНІ МЕДІА ЯК ІНСТРУМЕНТ РЕАЛІЗАЦІЇ ІНФОРМАЦІЙНОЇ ДІЯЛЬНОСТІ В БІЗНЕСІ

<p><strong><em>The purpose</em></strong><em> of the study is to understand the role and capacity of corporate media in the implementation of information activities of business structures with different groups of the public.</em><em></em></p><p><strong><em>Research methodology. </em></strong><em>During the study of theoretical and methodological base on the peculiarities of corporate media functioning in the modern information space, methods of analysis and synthesis were used; in the process of determining the main directions of information activities in the field of business descriptive method and method of generalization were applied; to reveal the aspects of implementation of business companies information support on practical samples the method of reception was used.</em><em></em></p><p><strong><em>Results.</em></strong><em> The author characterizes corporate media as one of the basic information and communication tools for providing information support to business structures in the process of interaction with people to meet their information needs. The paper reveals modern tendencies in the organization of this type of communications and describes the forms of their realization actualized by modern technological possibilities. Various ways of information support of business companies through the use of corporate media are presented. The study of basic principles of business information support made it possible to identify the powerful potential of corporate media in contact with various groups (external and internal), in forming and maintaining the image of the organization, its reputational (intangible) capital, in implementation of corporate social responsibility (humanization of business), and also in representation of this type of media as an important component of modern integrated marketing communications.</em><em></em></p><p><strong><em>Novelty.</em></strong><em> The novelty of the problem is to understand the specifics of the implementation of information activities through the prism of real practices of corporate media business companies. The study also presents corporate media as an information and communication complex tool for multifunctional information needs of stakeholders.</em><em></em></p><p><strong><em>Practical significance.</em></strong><em> The analysis provides an opportunity to summarize and systematize the main areas of information support through corporate media.</em><em></em></p><p><strong><em>Key words:</em></strong><em> corporate media (press, media, publications), branded periodicals, image, reputation, information support, information activities (business), data support, integrated marketing communications.</em><em></em></p>

Spontaneous State Detection Using Time-Frequency and Time-Domain Features Extracted From Stereo-Electroencephalography Traces.

As a minimally invasive recording technique, stereo-electroencephalography (SEEG) measures intracranial signals directly by inserting depth electrodes shafts into the human brain, and thus can capture neural activities in both cortical layers and subcortical structures. Despite gradually increasing SEEG-based brain-computer interface (BCI) studies, the features utilized were usually confined to the amplitude of the event-related potential (ERP) or band power, and the decoding capabilities of other time-frequency and time-domain features have not been demonstrated for SEEG recordings yet. In this study, we aimed to verify the validity of time-domain and time-frequency features of SEEG, where classification performances served as evaluating indicators. To do this, using SEEG signals under intermittent auditory stimuli, we extracted features including the average amplitude, root mean square, slope of linear regression, and line-length from the ERP trace and three traces of band power activities (high-gamma, beta, and alpha). These features were used to detect the active state (including activations to two types of names) against the idle state. Results suggested that valid time-domain and time-frequency features distributed across multiple regions, including the temporal lobe, parietal lobe, and deeper structures such as the insula. Among all feature types, the average amplitude, root mean square, and line-length extracted from high-gamma (60–140 Hz) power and the line-length extracted from ERP were the most informative. Using a hidden Markov model (HMM), we could precisely detect the onset and the end of the active state with a sensitivity of 95.7 ± 1.3% and a precision of 91.7 ± 1.6%. The valid features derived from high-gamma power and ERP in this work provided new insights into the feature selection procedure for further SEEG-based BCI applications.

Imaging visuospatial memory in temporal lobe epilepsy-Results of an fMRI study.

PurposeImpairment of cognitive functions is commonly observed in temporal lobe epilepsy (TLE). The aim of this study was to assess visuospatial memory functions and memory-related networks using an adapted version of Roland’s Hometown Walking (RHWT) functional MRI (fMRI) task in patients with TLE.MethodsWe used fMRI to study activation patterns based on a visuospatial memory paradigm in 32 TLE patients (9 right; 23 left) and also within subgroups of lesional and non-lesional TLE. To test for performance, a correlational analysis of fMRI activation patterns and out-of-scanner neuropsychological visuospatial memory testing was performed. Additionally, we assessed memory-related networks using functional connectivity (FC).ResultsGreater contralateral than ipsilateral mesiotemporal (parahippocampal gyrus/hippocampus) activation was observed in left (n = 23)/right (n = 9) TLE. In lesional left TLE (n = 17), significant activations were seen in right more than left mesiotemporal areas (parahippocampal gyrus), while non-lesional left TLE patients (n = 6) showed significant bilateral (left>right) activations in mesiotemporal structures (parahippocampal gyrus). In left TLE, visuospatial cognitive testing correlated with fMRI activations in left (parahippocampal gyrus) and right mesiotemporal structures (hippocampus), characterized by greater fMRI activation being associated with better memory scores. In right TLE, higher scores in visuospatial memory testing were associated with greater fMRI activations in left and right insular regions. FC patterns of memory-related networks differ in right and left TLE.ConclusionWhile TLE in general leads to asymmetrical mesiotemporal activation, lesion-induced and non-lesional TLE patients reveal different memory fMRI activation patterns. In right TLE, insular regions try to compensate for impaired right mesiotemporal structures during the performance of visuospatial tasks. Underlying functional visuospatial memory networks differ in right and left TLE.

Социальная регуляция рисков пандемии в оценках молодежи

The article analyzes the attitude of young people to the actions of the Government of the Russian Federation to reduce the risks of a pandemic. The attitude contains multilevel ideas about what should be and what exists in the activities of government structures and is reflected in value judgments. They are considered in the mainstream of traditional analysis: in relation to age, educational level, types of activity; within the framework of the concept of self-regulation of youth life: in connection with archetypes, individual features of mentality, habitual attitudes. Despite the fact that the Government of the Russian Federation received unequivocal support from less than a third of the young people surveyed, the most critical were the groups of young people aged 18 to 29, who combine work and study and do not trust the executive power. The least critical are students and unemployed youth who trust the executive power authorities. The article substantiates the conclusion that the authorities have a stable support among young people, who share the archetypes of “guilt” and “good”, the value attitude “love for the motherland” and the high habitual attitude toward “reliability and constancy.” But the most significant factor that increases positive attitude to the institutional regulation of the risks of the pandemic is youth trust to the Government of the Russian Federation.

Inter-machine plasma perturbation studies in EU-DEMO relevant scenarios: lessons learnt for EM forces prediction during VDEs

Abstract To support the deployment of DEMO wall protection strategy, the development of comprehensive analyses is essential to understand the implications of transient perturbations on the plasma shape control and on the vertical stability, some of the most critical aspects to be considered in elongated plasmas. Therefore, the design activities of the DEMO limiter structures need the deep understanding of the effects induced by transient plasma perturbations coupled with one of the most severe load conditions occurring in tokamaks, the Vertical Displacement Event (VDE). Since Electromagnetic (EM) loads during VDE phases are among the DEMO limiters design drivers, this study focuses on predictive simulations of the final plasma position and of EM loads following a VDE. For this purpose, a multi-tokamaks study supported by the construction of an inter-machine database containing experimental transient plasma perturbations and VDEs from JET and ASDEX Upgrade (AUG) has been carried out. It aims at the characterization of some transient plasma perturbations that may lead to high control efforts by the vertical stability system in terms of variations of the plasma internal parameters and vertical displacements. Consequently, such experimental transient plasma perturbations have been properly scaled to DEMO reference geometries with different magnetic configurations, to be simulated in terms of plasma dynamical behaviour by means of MAXFEA code. Finally, initial predictive EM loads on DEMO limiter structures will be discussed in the case of VDEs following plasma perturbations.

Validation and Optimization of Activity Estimates of the FiR 1 TRIGA Research Reactor Biological Shield Concrete

FiR 1 is a TRIGA Mark II-type research reactor in Finland. It was in operation between 1962 to 2015 and will be dismantled in 2022 to 2023. Preliminary calculations of the activities in the reactor main structures were performed in an earlier stage of the decommissioning project. Samples of the activated parts of the reactor biological shield concrete were drilled in December 2018 to validate these estimates. This paper describes the calculations and gamma activity measurements performed for the activated concrete samples to determine the boundary between radioactive parts and concrete that can plausibly be free-released from regulatory control. The activities have been estimated with a two-step calculation process using the MCNP and ORIGEN-S calculation codes and measurements using an ISOCS gamma spectrometer with a high-purity germanium detector.

ГАМКергические препараты в терапии начальных форм дисциркуляторной энцефалопатии

В настоящее время все большее значение приобретают функциональные расстройства при цереброваскулярных заболеваниях: тревога, ларвированная депрессия, когнитивные нарушения, инсомния и др. Это и нейрокардиальная проблема, и психосоматическая патология, требующая пересмотра существующих рутинных схем фармакотерапии, более многовекторного патогенетического подхода к лечению. В статье приведены результаты открытого пилотного когортного проспективного клинического исследования среди пациентов с дисциркуляторной энцефалопатией 1–2-й стадии. У пациентов с цереброваскулярной патологией применяли препарат Гамалате В6, нормализующий психоэмоциональные и мнестические функции — краткосрочную и долговременную память, снижающий уровень личностной и ситуативной тревожности. Под влиянием курсового приема Гамалате В6 улучшается мозговое крово­обращение: увеличивается скорость кровотока и снижается периферическое сопротивление в экстракраниальных сосудах каротидного бассейна. Гамалате В6 гармонизирует активность таламокортикальных структур (увеличивает мощность альфа-ритма на фоне снижения ЭЭГ-мощности подкорковых структур, генерирующих медленные ритмы) и симпатико-парасимпатический баланс вегетативной нервной системы по оценкам вариабельности ритма сердца.