Under the action of wind load, the foundation ring of the fan will generate stress concentration and alternating stress, leading to fatigue failure. Based on the average wind speed obtained from the supervisory control and data acquisition (SCADA) system, the orthogonal expansion method of random pulsating wind field and the number theory point selection method are used to calculate and simulate the corresponding pulsating wind speed time series, and then calculate the wind speed time series and wind load time series. Based on the ABAQUS finite element software, a model of a 5 MW wind turbine is established. The modal analysis is used to obtain the modal vibration pattern and the intrinsic frequency to verify the reasonableness of the structural modeling. Subsequently, the wind load time series is applied to the wind turbine model to obtain the stress time series using instantaneous modal dynamic analysis (Modal dynamics). The stress time series at the location of maximum stress concentration in the foundation ring is extracted, and the stress time series with the same stress amplitude is obtained through conversion, which has Wiener characteristics. After obtaining the stress amplitude using the rainflow counting method, the fatigue reliability is calculated based on the structural fatigue reliability analysis method considering the threshold crossing duration of the random process. This research holds reference significance for the calculation of fatigue reliability under approximate working conditions.