Prosthetic treatment of the maxillectomy cases are difficult due to the problems to perform sufficient retention, stability and aesthetic. Separation of the oral and nasal passages, impairment of mastication, esthetic and phonetic problems are the main goals of treatment. In this study, the prosthetic treatment of the subtotal maxillectomy patient, who is diagnosed with adenoid cystic carcinoma was described. A patient-specific obturator was fabricated for problems regarding to reduced crest support stabilization and retention. The retention was obtained by certain parts of the obturator, one which is actively engaged to the defect undercuts and one which was designed for the limited opening of the patient's mouth. A latex tube was used for retention which was ligatured, using a 0.1 mm orthodontic wire, around a neighboring bulb portion which suits the defective undercut region. Due to the limitation of mouth opening, the obturator is designed to have a short bulb extension which is attached to the acrylic prosthesis base.