One of the main methods of treatment of patients with complete absence of teeth is the use of complete removable plate prosthesis (CRPP) made of acrylic plastics. Violation of the polymerization regime and increased amount of residual monomer in acrylic prostheses lead to a number of complications in the tissues of the prosthetic impression area. According to our previous experimental researches, the use of ozone therapy is a promising area for the prevention and treatment of inflammatory processes and microbial lesions of the oral mucosa. Therefore, the aim of our research was to evaluate the effect of monitoring the level of residual monomer in the bases of prostheses and the influence of ozone therapy on atrophic changes in the tissues of prosthetic impression area in the treatment of patients with CRPP.
 118 patients with CRPP were examined and underwent of orthopedic treatment. Patients were divided into the following groups:
 Group 1 consisted of 33 patients who underwent of orthopedic treatment with complete removable plate prostheses made of plastic "Ftorax" by conventional methods.
 Group 2 included 39 patients with complete removable plate prostheses made of plastic "Ftorax" with controlled level of residual monomer by the proposed method of spectrophotometry.
 Group 3 consisted of 46 patients with complete removable plate prostheses made of plastic "Ftorax" with controlled level of residual monomer by the proposed method of spectrophotometry using the course of ozone therapy.
 Each group was further divided into subgroups; the patients underwent of orthopedic treatment on the upper "a" and lower "b" jaw.
 The intensity of atrophic changes in alveolar processes of the jaws was assessed in the dynamics of orthopedic treatment in certain regions (A, B, C, D, E) of the prosthetic impression area and determining of the total atrophy of the alveolar process of the jaws after 1 week, 1, 3, 6, 12 months of a removable prosthesis using. Ozone generation was performed using the Ozone DTA (APOZA Enterprise Co., Ltd., Taiwan), which is recommended for clinical use in dental practice.
 There is a direct dependence of CRPP fixation on the intensity of atrophic changes in alveolar processes of the upper and lower jaws, which were less pronounced in patients with residual monomer control in prosthetic bases and in combination with ozone therapy of mucosa in the prosthetic impression area. Atrophic changes in mandibular alveolar processes have a more significant effect on the fixation of complete removable plate prostheses in comparison with atrophic changes of the upper jaw. A probable regularity was revealed during the period of 1-12 months of orthopedic treatment of patients with CRPP, which indicates more uniform atrophies in different areas A, B, C, D, E on the upper jaw but the atrophic changes are not uniform on the lower jaw. A course of ozone therapy of mucosa in the prosthetic impression area during orthopedic treatment of patients with CRPP in combination with control of the level of residual monomer in the bases of removable prostheses significantly slows down the process of atrophic changes.
 The obtained clinical results substantiate the possibility and expediency of using CRPP from acrylic plastic made with control of the level of residual monomer by the proposed method of spectrophotometry and the use of ozone therapy to prevent atrophic changes of alveolar processes of the jaws and prosthetic stomatitis.