The analogue experiments that produce seismo-acoustic events are relevant for understanding the degassing processes of a volcanic system. The aim of this work is to design an unsupervised neural network for clustering experimental seismo-acoustic events in order to investigate the possible cause-effect relationships between the obtained signals and the processes. We focused on two tasks: 1) identify an appropriate strategy for parameterizing experimental seismo-acoustic events recorded during analogue experiments devoted to the study of degassing behavior at basaltic volcanoes; 2) define the set up of the selected neural network, the Self-Organizing Map (SOM), suitable for clustering the features extracted from the experimental events. The seismo-acoustic events were generated using an ad hoc experimental setup under different physical conditions of the analogue magma (variable viscosity), injected gas flux (variable flux velocity) and conduit surface (variable surface roughness). We tested the SOMs ability to group the experimental seismo-acoustic events generated under controlled conditions and conduit geometry of the analogue volcanic system. We used 616 seismo-acoustic events characterized by different analogue magma viscosity (10, 100, 1000 Pa s), gas flux (5, 10, 30, 60, 90, 120, 150, 180 × 10−3 l/s) and conduit roughness (i.e. different fractal dimension corresponding to 2, 2.18, 2.99). We parameterized the seismo-acoustic events in the frequency domain by applying the Linear Predictive Coding to both accelerometric and acoustic signals generated by the dynamics of various degassing regimes, and in the time domain, applying a waveform function. Then we applied the SOM algorithm to cluster the feature vectors extracted from the seismo-acoustic data through the parameterization phase, and identified four main clusters. The results were consistent with the experimental findings on the role of viscosity, flux velocity and conduit roughness on the degassing regime. The neural network is capable to separate events generated under different experimental conditions. This suggests that the SOM is appropriate for clustering natural events such as the seismo-acoustic transients accompanying Strombolian explosions and that the adopted parameterization strategy may be suitable to extract the significant features of the seismo-acoustic (and/or infrasound) signals linked to the physical conditions of the volcanic system.