Offshore platforms located in seismically active areas may be subjected to different seismic effects during service. The seismic performance of offshore platforms under different earthquakes was studied using shaking table tests and finite element analysis (FEA). The dynamic properties, acceleration, displacement and strain responses of the scale model under near-field, far-field and offshore earthquakes were studied. On this basis, more consideration was given to soil-pile-structure interactions (SPSIs), and this finite element (FE) model was analyzed for seismic fragility using incremental dynamic analysis (IDA). By combining the results of the tests and FEA, it was found that the dynamic response of the platform was significantly larger under offshore earthquakes than under onshore earthquakes. The collapse resistance of offshore platform under offshore earthquakes was inferior to that under onshore earthquakes. Therefore, seismic performance assessment of long-period offshore platforms based on onshore earthquakes may overestimate its seismic capacity and pose potential risks to platforms in service.