High-performance polymers are used in different fixed prosthesis treatments due to their many advantages such as biocompatibility, shock absorption ability, high fracture resistance. The effects of marginal design on the forces on high-performance polymers are unknown. This study aimed was to investigate the stress distribution of different marginal designs on Polyetheretherketone (PEEK) and Polyetherketoneketone (PEKK) substructure materials, cortical bone and cancellous bone by finite element analysis. A first maxillary molar tooth was modeled in 3D using the "3D Complex Render" method. Considering the ideal preparation conditions (Taper angle was 6°, step depth was 1 mm, occlusal reduction was 2mm), four different configurations were modeled by changing the marginal design (chamfer, deep chamfer, shoulder 90°, shoulder 135°). PEEK, PEKK substructure, and composite superstructure were designed on created models. A total of 150N oblique force from two points and a total of 300N vertical force from three points were applied from occlusall. and the maximum principal stress, minimum principal stress, von Mises stress findings in the cortical bone, spongiose bone, and substructure were examined. The study was carried out by static linear analysis with a three-dimensional finite element stress analysis method. The highest maximum principal stress value in the cortical bone was observed when the PEEK+Shoulder 135° step at vertical force. The highest minimum principal stress value in the cortical bone was observed when the PEEK+Shoulder 90° step, and PEEK+deep chamfer step at oblique force. The highest maximum principal stress value in spongiose bone was observed when the PEEK+Shoulder 90° step. The highest minimum principal stress value in spongiose bone was observed when the PEEK+deep chamfer step at vertical force. The highest von Mises stress value in the substructure was observed when the PEKK+Deep chamfer step at oblique force. The lowest maximum principal stress value in the cortical bone was observed when the PEKK+Shoulder 135° step at oblique force. The lowest minimum principal stress value in the cortical bone was observed when the PEEK+Shoulder 135° step, and PEKK+shoulder 135° step at vertical force. The lowest maximum principal stress value in spongiose bone was observed when the PEEK+Shoulder 90° step. The lowest minimum principal stress value in spongiose bone was observed when the PEEK+Shoulder 135° step and PEKK+Shoulder 135° step at vertical force. The lowest von Mises stress value in the substructure was observed when the PEEK+Deep chamfer step at vertical force. When cortical and spongiose bone stress were evaluated, no destructive stress was observed. Considering the stresses occurring in the substructure the highest stress was observed in the chamfer step.
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