5th Minute Research Articles

Effectiveness of cellulose acetate composite membrane with the addition of zeolite additives to reduce TDS levels in peat water using a cross-flow reactor

The need for clean water continues to increase along with population and industrial growth, which causes a water crisis. Quantitatively, peat water has the potential to be managed as a source of clean water using membrane filtration. This study aims to compare the composition of the cellulose acetate-zeolite composite membrane in reducing TDS levels in peat water using a cross-flow reactor. Cellulose acetate-zeolite composite membranes were prepared by phase inversion technique using 15 wt.% cellulose acetate (CA), with variations in zeolite concentration (5%; 10%; 15%; 20% and 25%), contact time (20, 40 and 60 minutes), the reactor pressure was 1.5 bar, and the TDS concentration in the feed water was 1,201 mg/L. Membrane characterization was done through morphological analysis using a Scanning Electron Microscope (SEM) and tensile test analysis. Membrane performance is determined through permselectivity and permeability testing. The results showed that the highest flux value was obtained on a 5% cellulose acetate-zeolite membrane at the 20th minute, namely 78.8 L/m2.hour. The best composition was obtained on a 25% cellulose acetate-zeolite membrane with a tensile strength value of 54.089 MPa and a rejection value of 92%. Morphological characterization showed that the pore size of the cellulose acetate-zeolite composite membrane decreased after use because TDS particles covered it.

Predictive significance of intraprostatic volumetric parameters derived from early and standard time 68Ga-PSMA PET/CT images in newly diagnosed prostate cancer patients.

To investigate the relationship between intraprostatic 68Ga-prostate-specific membrane antigen (PSMA) uptake values and volumetric parameters derived from early pelvic and standard-time whole-body 68Ga-PSMA PET/computed tomography (CT) images in untreated prostate cancer (PCa) patients, and to assess the predictive significance of these data in relation to disease prognosis, comparing them with the Gleason score, clinical risk classification and the presence of metastatic disease detected in 68Ga-PSMA PET/CT imaging. Eighty-one newly diagnosed PCa patients underwent early phase pelvic imaging at the 5th minute and standard time whole-body imaging at the 60th minute. Various threshold values were used in intraprostatic delineations to compute maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), intraprostatic PSMA tumor volume and intraprostatic total lesion PSMA uptake. Correlations between early and standard time measurements, as well as changes in SUV parameters over time, were examined. The association of these values with Gleason score, clinical risk status (National Comprehensive Cancer Network), and metastatic disease was explored. SUVmax measurements from both early and standard time images distinguished all three groups (clinical risk scores, Gleason score and metastatic group), with standard imaging demonstrating statistical superiority in receiver operating characteristic analyses. Strong correlations were observed between early and standard-time PET parameters. Changes in intraprostatic SUVmax and SUVmean values over time did not exhibit predictive value. Although intraprostatic PSMA PET parameters generally aligned at both early and standard times, parameters obtained from standard time images showed more robust correlations with clinical risk scores, Gleason score and metastasis status in newly diagnosed, untreated PCa patients.

Simple Measurement of Conductivity of Colored Acrylic Sheets

In many applications, colored acrylic sheets require information on thermal conductivity values. However, thermal conductivity data has not been found in the literature and research publications, especially colored acrylic sheets. The purpose of this study was to investigate the heat conductivity value of colored acrylic sheets including transparent, cloudy, white, black, green and blue colors found in the market. This research was done with the experimental method of measuring the thermal conductivity of colored acrylic in a closed room four rectangles 80 cm x 40 cm x 40cm of 9 mm plywood coated with black paper and divided into two compartments and test material 40 cm x 40 cm x 0.3cm as patisi room. The heat source used is a 75watt incandescent lamp placed on one side of the room. Acrylic thermal conductivity is calculated based on temperature data at each measurement point reaching a steady state which is obtained at the 30th minute and taking into account the convection heat and air radiation in the test chamber. The results showed that pigment additives greatly affect the thermal conductivity value of acrylic and its value is lower than the conductivity value of acrylic colorless sheet transfaran.

Association between Fish Consumption during Pregnancy and Maternal and Neonatal Outcomes: A Statistical Study in Southern Italy.

Background: This research aimed to evaluate the association between the monthly consumption of fish (differentiated by type) and both gestational and neonatal outcomes. Methods: Women who were admitted for delivery in the last 6 months of 2023 were prospectively included and divided according to type of fish consumed (based on DHA and mercury content) and frequency of consumption. Neonatal outcomes included weight, length, head circumference, and 1st and 5th minute Apgar scores. Maternal outcomes were threats of abortion, preterm birth, gestational diabetes and hypertension, cesarean section, and differential body mass index (BMI). Results: Small-size oily fish with high DHA and low mercury content (type B fish) consumption was positively associated with neonatal weight and head circumference, and less weight gain in pregnancy. It was also significantly associated with lower incidences of gestational diabetes and hypertension, and cesarean section. Correlation between differential BMI and monthly consumption of fish resulted in statistical significance, especially in type B fish consumers. Conclusions: The consumption of type B fish was significantly associated with increased neonatal weight and head circumference and better maternal outcomes.

Evaluation of the Anesthetic Properties of Dexmedetomidine and Dexmedetomidine-Ketamine Combination and the Properties of Atipamezole as a Reversal Agent in Domestic Pigeons

The aim of this study was to determine the anesthetic efficacy of dexmedetomidine and ketamine alone and dexmedetomidine-ketamine combination and the effects of α2 adrenergic reversal atipamezole in domestic pigeons (Columba livia). In DX group, dexmedetomidine (80 μg/kg), in K group, ketamine (100 mg/kg) alone, in DXK group, dexmedetomidine (40 μg/kg) and ketamine (50 mg/kg) consecutively were administered intramuscularly (IM). Anesthetic depth and cardiopulmonary symptoms were monitored starting from the pre-injection moment (T0) till the 60th minute (T60). At T60, atipamezole at a dosage 4 times that of dexmedetomidine was injected intramuscularly to the DX group (320 μg/kg) and the DXK group (160 μg/kg). In the DX group, only minimal sedation, bradycardia, and a sudden drop in respiratory rate were seen (P<0.05). The cardiopulmonary parameter values in the DXK group were affected to a less-er extent compared to the DK group. In the DXK group, 22.47±0.64 minutes after atipamezole injection, all pigeons were on their feet. As a result, it was concluded that dexmedetomidine (80 μg/kg) alone should not be used in pigeons, and if it is needed to be used, cardiopulmonary parameters should be carefully monitored peri-anesthetically. Dexmedetomidine (40 μg/kg) and ketamine (50 mg/kg) can be used in clinical practices that require a moderate level of anesthesia. Atipamezole can safely be used at 4 times the dosage of dexmedetomidine in pigeons.

Effect of breed and sex on the body weight, slaughter traits, meat quality and meat texture parameters of rabbits

The purpose of the study was to determine the influence of breed on the growth, slaughter traits, quality traits and parameters of texture of meat obtained from Blanc de Termonde and Flemish Giant rabbits. Young animals were weaned on the 35th day of their life. The weight of animals was recorded from birth to the 84th day of life at 7-day intervals. The rabbits were slaughtered between 85th and 90th day of live. Hot carcass weight, chilled carcass weight and giblets weight (liver, lung and heart, kidneys) were recorded. The pH and the colour of the longissimus lumborum and biceps femoris muscles was measured in 45th minute and at 24 hours after slaughter. Shear force and texture parameters were measured. Flemish Giant achieve higher final body weight but lower dressing out percentage than Blanc de Termonde rabbits. Carcasses of Blanc de Termonde characterized with higher loin weight and fat content in carcass. The effect of breed fount to be significant for some components of meat colour like yellowness (b*) in 45th minute and lightness after 24 hours post mortem. The effect of sex found to be significant for acidity of meat and b* component in 45th minute after slaughter and on redness (a*) after 24 hours post mortem. Statistically significant differences between Flemish Giant and Blanc de Termonde rabbits in shear force and texture profile analysis (TPA) were stated. The sex of animals effected only on chewiness parameter for TPA of rabbit meat.

Показники ротаційної тромбоеластометрії при передчасних пологах

Disrupted maternal, placental, and/or fetal hemostasis leads to gestational disorders, including preterm birth (PR). A quick and convenient assessment of the coagulation profile is important for a premature newborn. Aim - to compare the indicators of hemostasis in mothers and newborns with different gestational ages using rotational thromboelastometry. Materials and methods. The study analyzed the indicators of the hemostatic profile in women in labor and their newborns using the fib-tem test on the ROTEM® delta device. Three groups of mothers and their newborns were studied: the Group I - at a gestation period of 37-41 weeks, the Group II - 28-34 weeks, the Group III - 22-27 weeks. Results. In the Group III prematures, blood clotting time (257.1±87.29ʺ) is longer than that of the Group I - 43.3±21.48ʺ and the Group II - 52.5±25.03ʺ. Angle α is larger in the Group I and the Group II - 47.6±12.49; 79.9±4.62; 76.7±4.84 (degrees). Amplitudes of contraction (5, 10 min, maximum) of the Group II are lower than the Group I by 10-22%. In the Group III, the amplitudes correlate with the concentration of fibrinogen up to 2 g/l - 4.6±1.39; 8.0±3.00; 7.9±5.56 (mm). The smallest lysis in the Group III (1.8±2.38%) versus the Group I and the Group II (17.1±2.34%, 8.1±2.50%. Maternal indicators of the amplitude of the coagulation are higher at a shorter gestational age. Conclusions. Maternal indicators of the amplitude of coagulation exceed the indicators of newborns by 1.5-2 times - 18.8±7.89 versus 17.4±7.04; 22.0±3.34 vs. 15.2±11.37 and 20.8±9.22 vs. 7.9±5.56 (mm). Blood clotting time of extremely premature newborns (257.1±87.29ʺ s) is longer than that of full-term and moderately premature infants (43.3±21.48ʺ; 52.5±25.03ʺ). Amplitudes of contractions of newborns of the Group III at the 5th minute are three times smaller, and at the 10th minute they are twice as small as in the Group I and the Group II - 4.6±1.39; 13.2±3.34; 16.2±5.38 (mm) and 8.0±3.01; 15.5±4.34; 16.0±7.39 (mm). In the Group III, coagulation lysis is minimal (1.8±2.38% vs. 17.1±2.34%; 8.1±2.50%). The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. The authors declare no conflict of interest.

Does Articular Pressure Change Vital Signs During Temporomandibular Joint Arthrocentesis?

Objective: The aim of this study was to compare the vital signs as mean arterial pressure and heart rate of patients undergoing two different temporomandibular joint (TMJ) arthrocentesis techniques.
 Methods: Thirty patients received TMJ arthrocentesis with either double puncture arthrocentesis (DPA) or single puncture arthrocentesis (SPA). Blood pressure and heart rate were assessed preoperatively, during the application of local anesthesia, and at needle insertion into the joint cavity, the 5th and 10th minute of the procedure, and the end of the procedure. 
 Results: The heart rate and mean arterial pressure were highest during anesthesia and needle insertion (P

Carbon based cobalt titanate perovskite nanocomposite: Synthesis, characterization, and excellent visible light driven photocatalytic performance

Titanium-based perovskite oxides are the promising photocatalysts for an efficient degradation of organic pollutants. However, charge carriers recombination and wide band gap energy are still the main challenges in their visible-light-driven photocatalytic applications of Titanate perovskites, ATiO3. The immobilization of Titanium-based perovskites on a carbonaceous substrate such as nitrogen-rich carbon nitride, can be considered as an excellent option for enhancing photocatalytic performance. Here, the CoTiO3/C3N5 nanocomposite was synthesized by simple reflux method and used for photocatalytic degradation of three organic pollutants including methylene blue (MB), tetracycline hydrochloride (TC), and bisphenol A (BPA). The results indicated that the photocatalytic activity of the CoTiO3 perovskite was considerably improved by introducing C3N5 nanosheets and fabricating CoTP/C3N5 nanocomposite. The crystalline structure of CoTiO3/C3N5 (CoTP/C3N5) nanocomposites was confirmed successfully by XRD analysis. The specific surface area of the synthesized CoTP/C3N5 nanocomposite was 8.15 m2/g calculated by N2 adsorption–desorption technology. In the 60th minute of the photocatalytic process, the degradation efficiency of MB, TC, and BPA by CoTP/C3N5 were obtained as 98.70, 60.33, and 92.90 %, respectively, which were higher than pristine CoTiO3 nanorods and C3N5 nanosheets. Electrochemical impedance analysis shows that the CoTP/C3N5 nanocomposite has good electrochemical performance. The improvement photocatalytic activity CoTP/C3N5 can be attributed to the suppressing the recombination of photogenerated electrons and holes and good electrochemical performance with high electron transfer capability. The results achieved from UV–Visible Diffused Reflectance Spectroscopy (DRS), mott-schottky measurements and the photocatalytic degradation experiments in the presence of scavengers confirmed the significantly accelerating the Z-scheme charge transfer mechanism where photoexcited carriers can migrate between CoTiO3 perovskite and C3N5 nanosheets.

Rancang Bangun Alat Pengasap Tipe Paralel

This research aims to design, manufacture and test a parallel type smoker which has an output that can be controlled and has uniform temperature in each smoker cabinet. In this research, design, assembly, testing and temperature regulation were carried out. This parallel type smoker has 3 main parts, namely the combustion stove, inlet pipe, and smoking cupboard. In the inlet pipe there is a faucet which functions as a control for the smoke output and temperature from the combustion stove to the smoking cupboard. In terms of testing, this tool was tested in several stages, namely trial 1, trial 2, and performance test. After the test is complete, the final stage is carried out, namely equalizing the temperature in each cupboard. The trial phase 1 was carried out with treatment on the operation of the smoke cupboard. Where the stages of operation of all cupboards are carried out simultaneously, then operation of 2 cupboards is carried out and one path is closed alternately. The results showed that the tool experienced problems in the form of unstable temperatures and leaks in the smoker cupboard, so it required patching with silicon. After design improvements have been made, trial 2 and performance testing are continued. Trial 2 was carried out to find out whether the tool still had problems or not before carrying out a performance test. The treatment for trial 2 was the same as that given during trial 1. As a result, the device had no leaks and the temperature was stable and the device was ready to operate at the 15th minute. After that, a performance test was carried out which had the same stages as trials 1 and 2. This is intended to see whether the tool is in accordance with the results during testing or not. After the performance test is carried out, the final stage is to equalize the temperature in each cupboard to produce the same and stable temperature. This equalization is done by adjusting the opening of the faucet valve on the inlet pipe. The results obtained were a parallel type smoker which had 3 smoking cabinets with the same temperature around 37oC. This temperature can used for low smoking temperature.Keywords: Design of Smoker, Parallel, Temperature.

Does Basal Morning Luteinizing Hormone (bLH) Predict Central Precocious Puberty (CPP) in Girls?

Background and Objectives: bLH is considered an excellent biochemical predictor of CPP. However, its utilization in clinical practice shows some uncertainties. This study aims to evaluate the diagnostic power of bLH and propose a diagnostic algorithm for CPP. Materials and Methods: We conducted a monocentric cohort retrospective study evaluating all females referred for suspicion of CPP between 1 January 2017 and 31 December 2020 who underwent a GnRH test. Auxological, hormonal, and instrumental data were collected, including pelvic ultrasonography and bone age (BA) assessment. Simple linear regression, t-test, and ROC tests were utilized to study the diagnostic value of basal hormone levels. Two hundred thirteen girls were included in the study. They were subdivided into two groups according to the results of the GnRH test: Group 1, with LH peak > 5 IU/L (pubertal) and 79 patients (37%), and Group 2, with an LH peak ≤ 5 IU/L (prepubertal) and 134 patients (63%). Results: The ROC curve showed that bLH level > 1.5 Ul/L best predicts a pubertal response to the GnRH test (AUC 0.8821, accuracy 82%), with low sensitivity (34%). The multivariate analysis found that bLH > 0.5 IU/L, basal FSH (bFSH) > 3.5 IU/L, bLH/bFSH ratio > 0.16, BA advancement > 1.7 years, uterine volume > 3.6 mL, longitudinal uterine diameter > 41 mm, and the presence of endometrial rhyme were significantly associated with a pubertal response at the GnRH test. An algorithm based on these features was created, and its application would reduce the number of GnRH tests by 34%. Overall, 96.2% of Group 1 patients reached the LH peak at the 30th minute of the GnRH test, supporting the hypothesis that the GnRH test duration could be reduced to 30 min. Conclusions: Morning bLH > 1.5 IU/L could be carefully used as a diagnostic predictor of CPP. The GnRH test, even reduced to 30 min, could be reserved for girls who show low intermediate morning bLH and specific clinical signs of pubertal development.

Can Nanobubble Ozone Liposomes Be A New Agent In The Fight Against Foodborne Infections?

In this study, a nanobubble ozone liposome solution containing 2% ZnCl2 was used. The aging tests were conducted according to the ASTM F 1980 [1] standards. The minimum inhibitory concentration (MIC) level of the nanobubble ozone liposome solution with 2% ZnCl2 was determined as 1.562 ppm for strains of Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 25922) by the CLSI M07 A9 [2] standard test method. To assess the time-dependent antibacterial effect of the nanobubble liposome solution with 2% ZnCl2, the solution's efficiency at a concentration of 2000 ppm and for different time intervals was tested on strains of Salmonella enterica subsp. enterica (ATCC® 14028™) and Listeria monocytogenes (ATCC® 7644™). The results showed that the antibacterial activity of the strains of S. enterica subsp. enterica started at the end of the 10th minute and the solution was effective after 30 minutes. For strains of L. monocytogenes, it was observed that the activity started at the end of the 2nd minute and the product was effective after the 10th minute. According to the ASTM F 1980 standards, it was found that the nanobubble ozone liposome solution retained its effectiveness in one-year stability tests. As a result, the nanoparticle liposome solution, a new product, does not lose its stability and effectiveness for a long time, contrary to what is known. Although the half-life of gaseous ozone is as short as 20 minutes, the stability in the nanoparticle liposome solution has been determined as at least one year. Since nanoparticle liposome solution is a natural and slow-release product, nanobubble ozone liposome solution with 2% ZnCl2 may be used as a newly developed agent against contaminations in food processing facilities caused by biofilm-forming microorganisms through the use in disinfections of surfaces that are in direct contact with food products.

Evaluation of Analgesic Nociceptive Index in intraoperative and postoperative pain management in general anesthesia applied with two different methods

Aim: Effectiveness of analgesic nociceptive index (ANI) monitoring in predicting both intraoperative and postoperative early pain in neurosurgery patients undergoing lumbar spinal surgery. The patients were administered general anesthesia using different anesthesia management techniques.Method: The study included a total of 60 patients with American Society of Anesthesiologist (ASA) I-III. The patients were randomly divided into two groups of 30 each using the closed envelope method. Group T received total intravenous anesthesia (TIVA) with remifentanil-propofol, while Group D with desflurane-remifentanil. Non-invasive ANI monitoring was applied to patients undergoing lumbar spinal surgery, and ANI, heart rate, systolic/diastolic arterial pressure values were recorded before and after induction, skin incision, major muscle incision, laminectomy, right-left fasciectomy, screw fixation, after extubation and during the postoperative period. Post-operative heart rate, ANI value, mean arterial pressure values, and visual analog scale (VAS) values were measured.Results: No statistically significant difference was found in terms of the demographic data of the patients. According to the groups, no statistically significant difference was found between the ANI and VAS measurements of the cases at the postoperative 5th minute (P=0.261), postop 10th minute (P=0.379), postop 15th minute (P=0.673), postop 30th minute (P=0.784) and postop 60 minute (p =0.750).Conclusions: In our study on lumbar spine surgery, we could not detect any significant relationship between ANI monitoring and VAS values in the early postoperative period. There was no difference in ANI and VAS with either anaesthetic technique. In light of the results of our study, we believe that more studies are needed on the use of ANI monitoring in the early postoperative period.

Comparison of antimicrobial efficacy of different disinfectants on the biofilm formation in dental unit water systems using dip slide and conventional methods: A pilot study.

Biofilm formation in dental waterlines brings opportunistic infections, especially for immunosuppressive patients. This study aimed to determine biofilm-forming microorganisms by various methods and investigate disinfectants' effects on biofilm. In the study, samples were obtained from the waterlines of 10-15 aged six dental units, before (0 min.) and after chlorine dioxide (ClO2) and hypochlorous acid (HOCl) treatment (1, 5, 10, 20, and 30 min.), and total colony counts were performed using conventional surface smear method (SSM) and dip slide method (DSM). The Congo red agar and Christensen methods were used to examine the biofilm-forming properties of the isolates. Monitoring of biofilm presence was also visualized by SEM scanning. When DSM and SSM are compared in all units where ClO2 and HOCl are applied, DSM can detect bacterial growth even during periods of greater exposure to disinfectant application. Although DSM can achieve a value approaching 3% even at the 10th minute in units treated with HOCl; SSM does not show reproduction at the same disinfectant exposure and duration; It was observed that in the units where ClO2 was applied, the growth was no longer observed at the 10th minute with DSM, and SSM, 50% growth in the first minute of the units treated with ClO2 could not be detected in the 5th minute. It is concluded that it can be advisable to routinely disinfect the dental unit water systems with non-toxic doses of ClO2 application before patient treatments in clinics and also to perform contamination controls at regular intervals with DSM, which is a sensitive and very practical method. It has been observed that the dip slide method can count bacteria more sensitively than conventional methods in dental water systems without the need for experienced personnel and equipment. The difference between biofilm formation in water systems before and after disinfectant exposure in SEM examinations is remarkable. The effects of ClO2 and HOCl on biofilm were investigated and bacterial growth was inhibited in dental units between 5 and 10 minutes with both disinfectants.

Effect of early vitamin D supplementation on the incidence of preeclampsia in primigravid women: a randomised clinical trial in Eastern Democratic Republic of the Congo

BackgroundPrevious studies have reported the association between maternal vitamin D deficiency and preeclampsia. However, the efficacy of vitamin D supplementation in reducing the occurrence of preeclampsia remains unclear. The objective of this study was to evaluate the effect of cholecalciferol supplementation on the incidence of preeclampsia in primigravid women and its related maternal and foetal outcomes.MethodsA single-blinded clinical trial was conducted in fourteen antenatal care health facilities in the North (Goma, Mwesso, Nyiragongo) and South Kivu (Bukavu-Panzi) provinces of the Democratic Republic of Congo from March 1, 2020, to June 30, 2021. A total of 1300 primigravid women not exceeding 16 weeks of gestation were randomised with a 1:1 ratio to either the supplemented (A) or control (B) group. Each pregnant woman (A) presenting for antenatal care received a single monthly dose of cholecalciferol (60,000 IU) orally for 6 months. The control group received no vitamin D supplementation or placebo. Serum 25(OH)D was measured at recruitment and at 34 weeks of gestation. Outcomes were assessed monthly until delivery.ResultsThe median maternal age was 21 years (14–40), while the median gestational age was 15 weeks (5.4–29.0). A significant reduction in the risk of preeclampsia [RR = 0.36 (0.19–0.69); p = 0.001] and preterm delivery [RR = 0.5 (0.32–0.78); p = 0.002] was observed in the intervention group. An RR of 0.43 [(0.27–0.67); p < 0.001] was found for low birth weight. The RR for caesarean section was 0.63 [(0.52–0.75); p < 0.001]. The APGAR score at the 5th minute (p = 0.021) and the size of the newborn were significantly higher in the supplemented group (p = 0.005).ConclusionA single monthly dose (60,000 IU) of vitamin D supplementation, started in earlypregnancy, significantly reduced the incidence of preeclampsia and its maternal and foetal complications.Trial registrationISRCTN Register with ISRCTN46539495 on 17 November 2020.

Dexketoprofen versus Tenoxicam in Acute Severe Pain Due to Primary Dysmenorrhea.

To evaluate the analgaesic efficacy of tenoxicam and dexketoprofen in patients admitted to the Emergency Medicine (EM) Clinic with severe acute pain due to primary dysmenorrhea (PD). Randomised-controlled trial. Place and Duration of the Study: Emergency Medicine Clinic, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye, from January to December 2022. Patients presenting with PD, were divided into two groups of 60 each, administered 50 mg dexketoprofen and 20 mg tenoxicam intravenously. Visual analogue scale (VAS) scores were recorded at the 15th, 30th, 60th, and 120th minutes. VAS scores and ΔVAS scores were compared with the effectiveness of drugs, the need for rescue drugs and its side-effects. Intravenous (IV) dexketoprofen was administered to 60 of the patients and IV tenoxicam was administered to another 60. At the time of admission, mean VAS scores of the patients were 8.8 ± 0.9 for the dexketoprofen group and 8.6 ± 0.8 for the tenoxicam group. The VAS scores of the dexketoprofen group were found to be statistically significantly lower after 30 minutes with lower need for rescue analgaesics. ΔVAS scores of the dexketoprofen group were statistically significantly higher from the 30th minute. According to the VAS scoring, IV dexketoprofen was a more effective drug than IV tenoxicam in patients who were admitted to the EM clinic with severe pain due to PD. Dexketoprofen, Primary dysmenorrhea, VAS score.

Assessment of the Efficiency for Anesthesia of Two Agents in Teeth Removal: A Split-Mouth Research

ABSTRACT Aim: This study was intended to assess and relate the clinical anesthetic effectiveness of tramadol hydrochloride and lidocaine. Methodology: A clinical randomized split-mouth study was piloted among 40 patients who were otherwise healthy but needed to have their maxillary first premolars extracted bilaterally for orthodontic reasons were considered in the research. In each subject on one side (quadrant) of the arch 1.8 milliliters of lidocaine was given and on other side of the arch 1.8 milliliters of tramadol was given. On the basis of a list that was prepared by a computer, the randomization was done and the sides (quadrant) of the arches were decided for all the subjects, and the injections were given as local infiltration. Results: Lidocaine was found to be statistically more effective for overall anesthesia duration, despite the fact that there was no significant variance between the two drugs at the time when anesthetic effect began to take effect. Tramadol was found to be statistically more efficient than lidocaine when compared to the anesthetic activity at the 5th minute before extraction. Tramadol was found to be statistically more successful than lidocaine for both the patient’s degree of satisfaction and the rate at which wounds healed. Conclusion: Based on the findings of this research, it appears that tramadol and epinephrine could be used as a substitute to conventional local anesthetics during extractions of maxillary first premolar teeth during oral-maxillofacial surgery.

COMBINATION OF PHOTOCATALIST TiO2 (Titanium Dioxide) AND H2O2 (Hydrogen Peroxide) IN LAUNDRY WASTEWATER TREATMENT

Any laundry operation will discharge the waste water directly to the water surface, which can lead to pollution in the water. One method that can be used to treat laundry wastewater is a photocatalytic method with TiO2 (Titanium Dioxide) as an UV-assisted catalyst that is combined with a strong H2O2 oxidizer to produce OH (hydroxyl radical) to oxidize pollutants. The study aims to determine the differences in pH, TSS, BOD, COD, and Phosphate separation values with combination of TiO2 and H2O2 doses with variations in UV exposure time for 30, 60, and 90 minutes. A good quality TSS level obtained in the 60th minute with a dose of 1 g TiO2 and in combination with 10 ml H2O2 can reduce TSS levels by 20 mg/l from the initial TSS with a residual weight of 180 mg/L. A decrease in the quality COD level at a 90 minute clearance time with a dosage of 1 gr TiO2, in a combination of 10 ml H2O2, can reduce the COD levels by 32.5 mg/ l from the original COD value of 89.1 mg/l. A reduction in the phosphate level achieved at the cleaning time of 30 minutes at a combined dose of 4 gr TiO2 in a 40 ml combination, can lower the phosphatic level by 0.05 mg /l from the starting value of 5.61 mg/l and already meet the quality standard of laundry waste water.

Do Maternal Heart Diseases Affect Fetal Cardiac Functions?

To investigate whether fetal cardiac function is affected by underlying heart disease in pregnant women. A total of 100 pregnant women who were ≥34 gestational weeks were included in the study, 40 in the maternal heart disease (MHD) group diagnosed with heart disease and 60 in the control group. All cardiac diseases in pregnant women were diagnosed preconceptionally and categorized according to the New York Heart Association (NYHA) classification system. Fetal cardiac functions of study groups were evaluated by M-mode, color tissue Doppler imaging (c-TDI), and pulsed wave Doppler. Tricuspid annular plane systolic excursion and myocardial performance index (MPI) values were significantly higher and isovolumetric relaxation time was prolonged in the MHD group. The MPI value was found higher in MHD group with NYHA Class II compared to those with NYHA Class I. No significant change in any of the fetal tricuspid annular peak velocity values measured by c-TDI in the MHD group. There were no differences in fetal cardiac functions and perinatal outcomes between pregnant women with acquired and congenital heart diseases. Patients in NYHA Class II had lower birth weight, 1st and 5th minute APGAR scores, and higher neonatal intensive care unit admission rates. Underlying heart diseases in pregnant women can cause alterations in the systolic and diastolic function of the fetal heart. High fetal MPI values detected in cardiac patients may indicate that cardiac pathologies during pregnancy affect fetal cardiac globular myocardial function. Cardiac pathologies that progress with restricted physical activity may cause changes in fetal cardiac function and may be associated with adverse perinatal outcomes.

Lidocaine, Esmolol, and Beyond: A Comprehensive Analysis of Hemodynamic Stress during Laryngoscopy and Intubation

Aim: To evaluate the haemodynamic stress response in combination of lidocaine and esmolol versus lidocaine or esmolol alone during laryngoscopy and intubation Methods: This research comprised 60 patients who provided written permission and met the inclusion and exclusion criteria. Selected patients were randomly assigned to one of three groups based on a computer-generated random number: lignocaine 1.5 mg/kg (n=40), esmolol 2mg/kg (n=40), or lignocaine 1mg/kg and esmolol 1mg/kg (n=40). This research comprised patients aged 20 to 42 who had elective procedures under general anaesthetic and had ASA I and II. Patients with contraindications to beta blockers, such as bronchial asthma, COPD, a basal heart rate of 60 beats per minute, respiratory impairment, and documented reactions to local anaesthetics. Results: There were no significant variations in age, preoperative heart rate, or blood pressure between the groups. Males and females were approximately equally dispersed throughout all groupings. Following the delivery of the test medicines, all three groups saw a substantial drop in heart rate (Group E 61.23±3.64, Group L 73.25±5.36, Group LE 72.23±5.36) (p&lt;0.001). Four Group E patients developed bradycardia. (HR &lt;60). Although both Group LE and Group L showed near baseline values, Group L showed near baseline values until the third minute, whereas Group LE showed a continuous reduction in heart rate rates. After 30 minutes, all three groups' heart rates were statistically insignificant. Following induction and administration of the test medicines, systolic, diastolic, and hence mean arterial blood pressure lowers gradually in all three groups (p&lt;0.001). (This is for systolic blood pressure.). Group E 97.36±5.69, Group L 125.39±6.36, Group LE 116.78±4.78) Group E 60.034.69, Group L 82.935.36, Group LE 72.034.78) (Group E 72.10±3.69, Group L 96.90±3.85, Group LE 86.44±2.87) Before intubation, patients in Group E experienced substantial decreases in systolic, diastolic, and mean arterial blood pressure (less than 20% of baseline). Following intubation, blood pressure levels in Group LE were near baseline until the 30th minute (p&lt;0.001). Group E had a consistent fall in all three blood pressure readings following intubation until the fifth minute. Group E's blood pressures were likewise around baseline at the 15th and 30th minutes. Until the 15th minute, Group L had a considerable rise in all three blood pressures. Conclusion: As a result, esmolol and lidocaine together are a safe and effective strategy to minimise laryngoscopy responses to intubation and extubation, lowering myocardial oxygen consumption and the risk of myocardial ischemia under general anaesthesia.