Daily Users Research Articles

The Use of Daily and On-Demand Oral Pre-Exposure Prophylaxis Dosing Strategies Among Young Adult Gay, Bisexual and Other Men who have Sex with Men Enrolled in an mHealth Adherence Intervention.

Pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention option for gay, bisexual and other men who have sex with men (GBMSM). However, with newer PrEP options, a greater understanding of whether and why GBMSM switch dosing strategies is needed to inform clinical practice and research. We assessed the dosing strategies (daily or on-demand) of GBMSM enrolled in an mHealth PrEP adherence pilot intervention at four timepoints over approximately 10 months. Among GBMSM with complete data (n = 66), a consistent daily dosing strategy was used by most (73%) participants across all time points, while on-demand PrEP was used at least once during the study period by 27% of participants. A higher percentage of on-demand PrEP users self-reported as Asian/Pacific Islander and had less positive attitudes toward PrEP, adjusting for key sociodemographic variables and intervention arm. Daily PrEP users reported high numbers of sexual partners, and the primary reason that they would switch to on-demand PrEP is reduced sexual activity. At the final assessment, 75% of participants were taking daily PrEP, of whom 27% reported that they would like to switch to another option, including on-demand and long-acting injectable PrEP. While findings were largely descriptive, they showed that switches in PrEP dosing strategies are relatively common and PrEP strategy choice may vary across racial and ethnic groups.

Cannabidiol Reduces Nicotine Withdrawal Severity and State Anxiety During an Acute E-cigarette Abstinence Period: A Novel, Open-Label Study.

Introduction: Despite efforts to curb nicotine use, 8.1 million adults in the United States use e-cigarettes. Notably, the majority of nicotine-containing e-cigarette users report wanting to quit in the near future, yet there is a dearth of research surrounding intervention efforts. Cannabidiol (CBD) has potential to facilitate e-cigarette quit attempts by decreasing withdrawal symptom intensity and anxiety during nicotine e-cigarette abstinence. Methods: This study employed an open-label, crossover design (n=20) to test the hypothesis that among daily nicotine-containing e-cigarette users, oral administration of 320 mg CBD would reduce self-reported nicotine withdrawal severity and state anxiety following a 4-h e-cigarette abstinence period compared to withdrawal and anxiety reported after abstinence in the absence of CBD. Results: After controlling for participants' positive CBD expectancies, results were consistent with hypotheses, suggesting CBD reduced both nicotine withdrawal symptom severity and state anxiety during e-cigarette abstinence. Conclusion: These preliminary findings suggest testing the impact of CBD on e-cigarette cessation attempts is warranted.

Blood cannabinoid molar metabolite ratios are superior to blood THC as an indicator of recent cannabis smoking

Introduction Cannabis use is a growing concern in transportation and workplace incidents. Because Δ9-tetrahydrocannabinol is detectable after acute psychoactive effects have resolved, it has limitations as an indicator of recent usage or potential impairment. Methods In an observational study of driving and psychomotor performance, we measured whole blood Δ9-tetrahydrocannabinol plus its metabolites 11-hydroxy-Δ9-tetrahydrocannabinol and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol by liquid chromatography with tandem mass spectrometry at baseline and 30 min after starting a 15-minute interval of smoking cannabis in 24 occasional and 32 daily cannabis smokers. We calculated two blood cannabinoid molar metabolite ratios: 1) [Δ9-tetrahydrocannabinol] to [11-nor-9-carboxy-Δ9-tetrahydrocannabinol] and 2) ([Δ9-tetrahydrocannabinol] + [11-hydroxy-Δ9-tetrahydrocannabinol]) to [11-nor-9-carboxy-Δ9-tetrahydrocannabinol]. We compared these to blood [Δ9-tetrahydrocannabinol] alone as indicators of recent cannabis smoking. Results Median Δ9-tetrahydrocannabinol concentrations increased from 0 (<limit of detection 0.2 µg/L) at baseline to 5.6 µg/L post-smoking in occasional users. Among daily users, these were 2.7 µg/L at baseline and 21.3 µg/L post-smoking. Median molar metabolite ratio 1 increased from 0 at baseline to 0.62 post-smoking in occasional users and from 0.08 at baseline to 0.44 post-smoking in daily users. The median molar metabolite ratio 2 increased from 0 to 0.76 in occasional users and from 0.12 to 0.54 among daily users. A molar metabolite ratio 1 cut-point of 0.18 yielded 98% specificity, 93% sensitivity, and 96% accuracy for identifying recent cannabis smoking. A molar metabolite ratio 2 cut-point of 0.27 yielded 98% specificity, 91% sensitivity, and 95% accuracy. The receiver operating characteristic curves for molar metabolite ratio 1 and molar metabolite ratio 2 were not statistically different (P > 0.38). By comparison, a cut-point for Δ9-tetrahydrocannabinol of 5.3 µg/L yielded 88% specificity, 73% sensitivity, and 80% accuracy. Conclusions In occasional and daily users, the blood cannabinoid molar metabolite ratios were superior to whole blood Δ9-tetrahydrocannabinol as indicators of recent cannabis smoking. We recommend measurement and reporting of Δ9-tetrahydrocannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol, and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol, and their molar metabolite ratios in forensic and safety investigations.

Cyber Literacy Skills of Estonians: Activities and Policies For Encouraging Knowledge-Based Cyber Security Attitudes

With the advent of COVID-19, people spent more time at home. Countries, societies, companies and individuals suddenly became dependent on cyberspace overnight. Work, shopping and leisure meant we became more than ever weak to the risks of cyberspace. The human factor makes people the “key” to otherwise technically hardly penetrable systems – criminals play on people’s greed, emotions, happiness, etc.&#x0D; It is no surprise that Estonians are more active daily internet users compared to the rest of the Europeans. But what is being done in Estonia at the national level, as well as in cyber protection organisational level, to raise the awareness of residents about cyber security? What else should be done to reduce victims among ordinary citizens and how to protect various important public and private organisations from the consequences of the cyber-risky behaviour of their employees? What is the role of libraries in promoting cyber security awareness? A human error is a central target of cyber attacks, phishing scams, and data breaches. Cyber criminals are becoming more and more inventive. It is important to understand that cyber security risks can be managed and mitigated, but not completely eliminated. Increasing security awareness is the only factor that can help limit breaches caused by human frailty.

Question of the Day: A Learning Success (S10.001)

<h3>Objective:</h3> To demonstrate the successful implementation of the American Academy of Neurology (AAN) Question of the Day (QOD) mobile application and its value to AAN members. <h3>Background:</h3> QOD, launched in 2020, provides daily board exam–style multiple-choice questions in two tracks: one for practicing neurologists and one for medical students. Questions for neurologists follow a yearly curriculum based on the American Board of Psychiatry and Neurology (ABPN) Maintenance of Certification (MOC) content outline. Topics include a wide variety of neurology subspecialties. Each question is accompanied by a detailed rationale and current references, many of which are hyperlinked to peer-reviewed resources. Users can earn up to 29 self-assessment continuing medical education (SA-CME) per year, which is 2 SA-CME per 25 QOD questions. The ABPN has approved QOD as part of a comprehensive lifelong learning program. <h3>Design/Methods:</h3> Data collected from QOD since April 2021 include activity by AAN member type, total active daily users, number of CME earned, and program evaluation data. <h3>Results:</h3> Total users per year were 5.6K, 9.5K, and 11K for 2020, 2021, and 2022, respectively, with practicing neurologists (25%) and junior (59%) AAN members the most engaged, and with participation from 123 countries. Average daily users increased from 1.4K in 2021 to 1.5K in 2022, with weekly (2.7K) and monthly (4.3K) usage comparable in 2021 and 2022. In total, 8.7K hours of SA-CME have been claimed in 2022 compared with 5.8K in 2021. Satisfaction has remained high since launch and is currently 99%. Users report that the questions are useful, fair, balanced, and of high quality. <h3>Conclusions:</h3> Since its introduction in 2020, QOD has become a very popular, effective continuing education program for AAN members. There has been substantial growth of new users each year while maintaining a strong contingency of daily users. <b>Disclosure:</b> Dr. Seachrist has received personal compensation for serving as an employee of American Academy of Neurology. The institution of Dr. Seachrist has received research support from Bristol Myers Squibb. Dr. Seachrist has a non-compensated relationship as a Topic Group Member with American Academy of Neurology that is relevant to AAN interests or activities. Ms. Shindoll has nothing to disclose. The institution of Dr. Pawar has received research support from ACGME "Back to Bedside" Grant support. Dr. London has nothing to disclose. Dr. Khan has nothing to disclose. The institution of Dr. Kraakevik has received research support from Parkinson Foundation. Dr. Graber has a non-compensated relationship as a Editorial Board member with Neuro-Oncology: Practice, published by Oxford that is relevant to AAN interests or activities. Dr. Graber has a non-compensated relationship as a Editorial Board Member with Journal of Pain and Symptom Management that is relevant to AAN interests or activities. Dr. Graber has a non-compensated relationship as a Board of Directors with American Society of Neuroimaging that is relevant to AAN interests or activities. Dr. Graber has a non-compensated relationship as a Certification Exam Committee Member with United Council of Neurogical Subspecialties that is relevant to AAN interests or activities. Dr. Graber has a non-compensated relationship as a Question of the Day ’app’ committee with American Academy of Neurology that is relevant to AAN interests or activities. Dr. Graber has a non-compensated relationship as a Editorial Board Member with Practical Neurology (BMC) that is relevant to AAN interests or activities. Dr. Gliksman has nothing to disclose.

Cannabis Use Disorder Symptoms in Weekly Cannabis Users: A Network Comparison Between Daily Cigarette Users and Nondaily Cigarette Users.

Background: Concurrent use (co-use) of cannabis and tobacco is common and associated with worse clinical outcomes compared with cannabis use only. The mechanisms and interactions of cannabis use disorder (CUD) symptoms underlying co-use remain poorly understood. Methods: We examined differences in the symptom presence and symptom network configurations between weekly cannabis users who use tobacco daily (co-users, n=789) or non- or nondaily (nondaily co-users, n=428). Results: First, we identified a range of symptoms (craving, failed reduce or quit attempts, neglected responsibilities, and negative social effects) that are most central to the highly interconnected CUD symptom network. Risky cannabis use was mostly associated with negative social and health effects, and independent of other CUD symptoms. Craving symptoms act as a bridge between different CUD and withdrawal symptoms. Among co-users, (1) craving is more strongly associated with negative psychosocial effects, (2) feelings of depression and negative health effects are more central to the network, and (3) the negative health effects are more strongly associated with failed attempts to reduce or quit attempts compared with nondaily co-users. Discussion: Our results go beyond existing findings focused on the mere increase in CUD symptom presence, and speak to the potential synergistic effects of co-use on dependence and withdrawal symptoms. We outline clinical implications with respect to targeting specific CUD symptoms in co-users, and point to future research to disentangle tobacco and cannabis craving symptoms.

COVID-19 Vaccination and Gaps in India.

The important variables that influence how many people are vaccinated against coronavirus disease (COVID-19) in India include vaccine skepticism, socioeconomic status, and multi-dimensional deprivation. Our preliminary research suggests that uncertainty about the safety of the COVID-19 vaccine has a large and detrimental effect on immunization rates. The Crucial Subsets Survey (CSS) is performed daily on Facebook to recruit participants for cross-section surveys by academic institutions, the Delphi Research Center, and the University of Maryland's Joint Program in Survey Methodology. Facebook will notify a portion of its daily users to take a vote. CSS adds behavior, attitude toward policy and preventive measures, economic consequences, and critical indicators to official reporting data. It has been estimated that a 30% drop in vaccination coverage may be attributed to a 1% rise in vaccine skepticism. Similarly, higher rates of multidimensional poverty are associated with lower rates of COVID-19 vaccine coverage. When the multidimensional poverty index (MPI), or the percentage of persons living in extreme poverty, rises by one unit, immunization rates fall by around half. It suggests that higher rates of socioeconomic hardship have unfavorable effects on health outcomes like vaccination rates. We also showed that gender is a major factor in influencing how internet availability affects vaccination rates and hesitation. We discovered that male vaccination rates went up in tandem with male internet use. This might be because of the digital divide and India's reliance on digital technologies like the COVID Vaccine Intelligence Network (COWIN), AAROGYA SETU, and Imphal, India, to assign and register for COVID-19 vaccinations, while males have greater digital excess than females. While male internet access is significantly and positively correlated with coverage, female internet access is significantly and negatively correlated with coverage. Women are less likely to seek medical care and have more vaccination reluctance than men, both of which contribute to this trend. The government's strategy for disseminating information about the COVID-19 vaccination should prioritize reaching out to women. In order to recruit more women to vaccination clinics, it is important to raise public awareness about the need for immunization among women via the media and community outreach.

Building a Timeline for LGBTQ+ Global Cinemas (1910–2019): Movie Production Trends from a Collaborative Internet Cinema Database

Building a Timeline for LGBTQ+ Global Cinemas (1910–2019): Movie Production Trends from a Collaborative Internet Cinema Database

The Dark Web: Privacy and Anonymity

Abstract: The Internet as a whole is a network of multiple computer networks and their vast infrastructure. The network consists of websites accessible through search engines such as Google, Firefox, etc. It's called the Surface Web. The Internet is further subdivided into the Deep Web – content that is unindexed and inaccessible to traditional search engines. The Dark Web is considered part of the Deep Web. It is accessible via TOR. Participants on the dark web are anonymous and hidden. Anonymity, confidentiality and the possibility of not being detected are three factors offered by special browsers like TOR and I2P. In this article, we discuss the impact of the Darknet in different social areas and provide results. It gives the number of daily anonymous darknet users (with TOR) in Kosovo and worldwide at the time showed the impact of hidden service sites and got search engine results from Ahimia and Onion City Dark Web. Anonymity on the dark web is not sufficiently verified. TOR strives to provide anonymous activity and aims to provide anonymous activity. Here are the results for showing the number of users and their location. calculations are based on IP addresses by country code, and accesses the sources of those addresses and reports the numbers in aggregate form. In this way,dark web users are indirectly represented. Another key factor is the number of anonymous network users on the dark web. In such a network, users are counted based on requests from directory clients (via TOR metrics) and the relay list is updated. Indirectly, the number of users calculated for the anonymous networks.

Effect of tenofovir-based HIV pre-exposure prophylaxis against HBV infection in men who have sex with men.

Men who have sex with men (MSM) are vulnerable to contracting HBV as a sexually transmitted infection. We evaluated the incidence of HBV infection (HBI) and the prophylactic effect of tenofovir-based pre-exposure prophylaxis (PrEP) on HBI in an MSM cohort. MSM who were older than 16 years were enrolled from January 2018 and followed up until June 2021 and tested for HIV, bacterial sexually transmitted infections, and HBsAg/ HBsAb and HBcAb every 3 months based on inclusion criteria, including HBsAg, HBcAb, HBsAb, and HIV negativity at enrollment. HBI was defined as seroconversion of HBsAg or HBcAb status. The log-rank test was used to evaluate the prophylactic effect of PrEP against HBI. As a substudy, individuals excluded from the main study due to HBs Ab positivity were evaluated for HBI incidence. Among 1577 MSM, 786 participants (546 PrEP nonusers, 131 daily PrEP users, and 109 event-driven PrEP users) met the criteria and were included. The annual incidence of HBV among PrEP nonusers (3.8%, 21 infections, with 559.5 person-years) was significantly higher ( p = 0.018, log-rank test) than that among daily PrEP users [0.77%, 1 infection (admitted nonadherence), with 129.3 person-years] and event-driven PrEP users (no infection with 93.8 person-years). Although the incidence of HBI and HIV infection decreased with PrEP use, the incidence of other sexually transmitted infections was higher in both daily and event-driven PrEP users. The annual incidence of HBV among HBsAb-positive and HBcAb-negative PrEP nonusers was 1.8% (3 infections, with 167.5 person-years). Tenofovir-based PrEP prevented HBI among MSM in a real-world setting.

The minor cannabinoid cannabigerol (CBG) is a highly specific blood biomarker of recent cannabis smoking

Introduction The determination of recent cannabis use is of forensic interest in the investigation of automotive crashes, workplace incidents and other mishaps. Because Δ9-tetrahydrocannabinol may persist in blood after psychoactive effects of intoxication resolve, particularly in regular users, short-lived minor cannabinoids such as cannabigerol have merited examination as adjunct indicators of recent cannabis inhalation. Methods As part of an observational cohort study, whole blood cannabinoids including cannabigerol were measured in whole blood by liquid chromatography with tandem mass spectrometry at baseline, and 30 minutes after initiation of a 15-minute supervised interval of ad libitum cannabis smoking in occasional (1–2 days/week over the past 30 days) (n = 24) and daily cannabis smokers (n = 32). Per protocol, subjects self-reported abstention from inhaling cannabis (>8 h) or ingesting cannabis (>12 h) prior to baseline measurement. Results At baseline, none of the occasional users had detectable cannabigerol (limit of detection = 0.2 µg/L), whereas cannabigerol was detectable post-smoking in 7 of 24 (29%). Among daily cannabis users, 2 of 32 (6%) had detectable cannabigerol at baseline, increasing to 21 of 32 (66%) post-smoking. The odds ratio for recent cannabis smoking associated with a detectable cannabigerol was 27 (95% confidence interval: 6.6, 110.3). In this mixed cohort of occasional and daily cannabis users, receiver operator characteristic curve analysis indicated that whole blood cannabigerol concentration of ≥ 0.2 µg/L had 96% specificity, 50% sensitivity, and 73% accuracy for identifying a 15-minute interval of ad libitum cannabis smoking initiated 30 minutes earlier. Post smoking blood Δ9-tetrahydrocannabinol (median = 5.6 µg/L in occasional users, 21.3 µg/L in daily users) was significantly correlated with post-smoking cannabigerol (P < 0.0001). Conclusion Whole blood cannabigerol may have forensic utility as a highly specific albeit insensitive biomarker of recent cannabis smoking.

Chronic caffeine consumption curbs rTMS-induced plasticity.

Caffeine is a widely used psychostimulant. In the brain, caffeine acts as a competitive, non-selective adenosine receptor antagonist of A1 and A2A, both known to modulate long-term potentiation (LTP), the cellular basis of learning and memory. Repetitive transcranial magnetic stimulation (rTMS) is theorized to work through LTP induction and can modulate cortical excitability as measured by motor evoked potentials (MEPs). The acute effects of single caffeine doses diminish rTMS-induced corticomotor plasticity. However, plasticity in chronic daily caffeine users has not been examined. We conducted a post hoc secondary covariate analysis from two previously published plasticity-inducing pharmaco-rTMS studies combining 10 Hz rTMS and D-cycloserine (DCS) in twenty healthy subjects. In this hypothesis-generating pilot study, we observed enhanced MEP facilitation in non-caffeine users compared to caffeine users and placebo. These preliminary data highlight a need to directly test the effects of caffeine in prospective well-powered studies, because in theory, they suggest that chronic caffeine use could limit learning or plasticity, including rTMS effectiveness.

Study of the association between cannabis use and sleep disturbances in a large sample of University students

Sleep complaints and cannabis use are common among University students and are related to detrimental effects on health. The aim of this study was to explore their association. This cross-sectional study based on the i-Share e-cohort included French students between 18 and 30 years old (n = 14,787). Frequency of cannabis use was categorized into daily, weekly, monthly, and never/rarely use. Sleep complaints were defined using four items (i.e., insomnia, sleepiness, poor sleep quality, and sleep deprivation). In the whole sample (mean age: 20.4 years, 75.5% of females), 22.7% had insomnia, 18.3% had sleepiness, 22.4% had poor sleep quality, 52.5% had sleep deprivation, and 5.8% used cannabis weekly or daily. After adjustment, the likelihood of insomnia was significantly higher by 45% in cannabis users compared to non-users. The estimates steadily increased with frequency of use, reaching a 2.0-fold higher likelihood of insomnia in daily users compared to never/rarely users. Results were similar for the other sleep complaints. These findings provide support for an association between cannabis use and sleep complaints, particularly insomnia, among University students. Though direction and causality cannot be established in this setting, these results suggest warning students and health professionals about the association between cannabis use and sleep complaints.

Disease progression rates in ambulatory Duchenne muscular dystrophy by steroid type, patient age and functional status.

Aim: To examinebenefits of corticosteroids for Duchenne muscular dystrophy (DMD) by age and disease progression. Methods: Data from daily steroid users (placebo-treated) were pooled from four phase 2b/3 trials in DMD. Outcomes assessed overall and among subgroups included changes from baseline to 48weeks in six-minute walk distance (6MWD), timed function testsand North Star Ambulatory Assessment total score. Results: Among 231 patients receiving deflazacort (n=127) or prednisone (n=104), observed differences in 6MWD favoring deflazacort over prednisone were significant for patients with relatively older age (≥8-years-old), greater disease progression (baseline timed stand from supine ≥5 s), or longer corticosteroid use (>3years). Conclusion: Daily deflazacort had greater benefits than daily prednisone particularly among older/more progressed patients.

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts Varies as a Function of Screening Criterion Used.

The authors recruited nineteen daily users of retail oral hemp-derived CBD products (≤0.3% Δ9-tetrahydrocannbinol; THC) and collected urine samples that were screened for 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THC-COOH), a metabolite of THC. Urine samples were aliquoted into two samples-one that was subjected to immunoassay (IA) testing and the other shipped to a third-party laboratory for confirmation testing. Findings showed that the daily use of oral hemp-derived CBD extracts consistently resulted in positive urine IA screening results for THC-COOH at the 20 ng/mL detection criterion; however, positive results at the 50 ng/mL criterion were rare. Confirmation testing of each sample using LC-MS/MS analysis showed a positivity rate of 42% (range 37-178 ng/mL) at the >15 ng/mL criterion, which was intermediate to the two IA screening tests, suggesting that the IA 20 ng/mL and 50 ng/mL tests used are subject to high rates of false positive and negative results, respectively. Therefore, efforts should be made to increase public awareness regarding the risk of positive drug test results following oral hemp-derived CBD product use.

Exploring the effects of COVID-19 on motorcycle riding patterns and its importance.

A motorcycle refers to a two-wheeled, personal mobility vehicle used for daily transportation and leisure activities. Leisure enables social interaction, and motorcycle riding could be an activity that facilitates social interactions and distancing. Therefore, grasping the importance of riding motorcycles during the pandemic-which involved social distancing and limited leisure activities-can be valuable. However, researchers have yet to examine its potential importance during the pandemic. Therefore, this study aimed to determine the importance of personal space and time spent with others in the context of motorcycle riding during the COVID-19 pandemic. We specifically explored the effects of COVID-19 on riding patterns and importance of riding motorcycle by examining whether these factors differed regarding changes in the frequency of motorcycle riding before and during the pandemic in daily and leisure-oriented transportation. Data were collected from 1,800 motorcycle users in Japan using a web-based survey conducted in November 2021. Respondents replied to questions concerning the importance of personal space and time spent with others attributed to motorcycle riding before and during the pandemic. Following the survey, we conducted a two-way repeated measures analysis of variance (two-factor ANOVA) and performed a simple main effect analysis using the SPSS syntax editor in case of interactions. The valid samples for motorcyclists with leisure motive (leisure-oriented users) and daily transportation motive (daily users) numbered n = 890 and n = 870, respectively (total n = 1,760, 95.5%). Each valid sample was divided into three groups based on the differences in motorcycle riding frequency before and during the pandemic: unchanged, increased frequency, and decreased frequency. The two-factor ANOVA results showed significant differences in the interaction effects for leisure-oriented and daily users regarding personal space and time spent with others. The mean value of the "increased frequency" group during the pandemic indicated significantly higher importance of personal space and time spent with others than the other groups. Motorcycle riding could enable daily transportation and leisure-oriented users to practice social distancing while simultaneously spending time with companions and alleviating loneliness and isolation during the pandemic.

Public Use of the "Your COVID Recovery" Website Designed to Help Individuals Manage Their COVID-19 Recovery: Observational Study.

At the start of the COVID-19 pandemic, unprecedented pressure was placed on health care services globally. An opportunity to alleviate this pressure was to introduce a digital health platform that provided COVID-19-related advice and helped individuals understand and manage their COVID-19 symptoms. Therefore, in July 2020, the Your COVID Recovery website was launched by the National Health Service of England with the aim of creating a practical tool that provides advice and support to individuals recovering from COVID-19. The website includes information on many of the key COVID-19 symptoms. To date, public use of the Your COVID Recovery website and user behavior remain unknown. However, this information is likely to afford insight into the impact of the website and most commonly experienced COVID-19 symptoms. This study aimed to evaluate public use of the Your COVID Recovery website, a digital health platform that provides support to individuals recovering from COVID-19, and determine user behavior during its first year of operation. Google Analytics software that was integrated into the Your COVID Recovery website was used to assess website use and user behavior between July 31, 2020, and July 31, 2021. Variables that were tracked included the number of users, user country of residence, traffic source, number of page views, number of session views, and mean session duration. User data were compared to COVID-19 case data downloaded from the UK government's website. During the study period, 2,062,394 users accessed the Your COVID Recovery website. The majority of users were located in the United Kingdom (1,265,061/2,062,394, 61.30%) and accessed the website via a search engine (1,443,057/2,062,394, 69.97%). The number of daily website users (n=15,298) peaked on January 18, 2021, during the second wave of COVID-19 in the United Kingdom. The most frequently visited pages after the home page were for the following COVID-19 symptoms: Cough (n=550,190, 12.17%), Fatigue (n=432,421, 9.56%), Musculoskeletal pain (n=406,859, 9.00%), Taste and smell (n=270,599, 5.98%), and Breathlessness (n=203,136, 4.49%). The average session duration was 1 minute 13 seconds. A large cohort of individuals actively sought help with their COVID-19 recovery from the website, championing the potential of this tool to target an unmet health care need. User behavior demonstrated that individuals were primarily seeking advice on how to relieve and manage COVID-19 symptoms, especially symptoms of cough, fatigue, and musculoskeletal pain. COVID-19 rehabilitation programs should use the results of this study to ensure that the program content meets the needs of the post-COVID-19 population.

A Hybrid Mechanism for Auto Text Categorization in Web Documents

Web personalization has become such a popular paradigm nowadays, that almost all e-commerce websites are including it in their websites. The main objective of web personalization is driven by grouping similar web pages. The text categorization principle becomes a challenge when daily users visit numerous pages. This paper develops a hybrid framework which categorizes the text extracted from a web document, by applying Neighbourhood Preserving Embedding algorithm and then Particle Swarm Optimization algorithm on the extracted text groups, resulting into a group of web documents which contain similar texts. The proposed mechanism relatively has a high performance which improves with time, and as the size of web documents increase, the particle swarm algorithm also evolves in its nature.

Trending Videos on YouTube

The following research paper explores the elements of trending YouTube videos. Marketers have a significant interest in YouTube trending videos as they can effectively structure products and service advertisements. As of 2022, data indicates that around 122 million daily users who watch roughly one billion hours of content visit YouTube. In the United States, an estimated 62 percent of YouTube users visit social media sites daily. Consequently, research on the features of trending YouTube videos can be highly informative for marketers looking to increase the effectiveness of their YouTube advertisement to facilitate efficient use of the marketing budget. An analysis of YouTube videos created between 2007 and 2016 can provide essential insight for marketers as they decide on advertisements.

Is Cycling Safe? Does It Look like It? Insights from Helsinki and Barcelona

Cycling constitutes a clean, healthy, and low-cost mode of transport. Therefore, the promotion of cycling is currently one of the main goals of administrations around the word. Former studies have shown that safety perception plays a fundamental role in the acceptance of bikes as a habitual mode of transport. In this context, this research aims to determine which variables and actions can give rise to this feeling of safety and, therefore, collaborate in the modal shift towards a more sustainable mobility. For this purpose, different strategies have been developed in two different contexts, Helsinki and Barcelona, using two different methodologies, namely expert interviews and analysis of survey data. Particularly, the methodology of analysis used includes descriptive statistics and path analysis. Results point out that safety perception highly depends on trip purpose, as significant differences are observed for daily users compared to those who cycle for sport reasons. Demographic characteristics (age, gender, etc.) and use patterns are also associated with different perceptions of safety and different behaviors. However, for any cyclist, the quality of the available infrastructure significantly influences his/her safety perception. Thus, the provision of good quality and well-structured cycling infrastructure is the most important initiative to promote cycling.