Classical Groups Research Articles

Arithmetic branching law and generic 𝐿-packets

Let G G be a classical group defined over a local field F F of characteristic zero. For any irreducible admissible representation π \pi of G ( F ) G(F) , which is of Casselman-Wallach type if F F is archimedean, we extend the study of spectral decomposition of local descents by Jiang and Zhang [Algebra Number Theory 12 (2018), 1489–1535] for special orthogonal groups over non-archimedean local fields to more general classical groups over any local field F F . In particular, if π \pi has a generic local L L -parameter, we introduce the spectral first occurrence index f s ( π ) {\mathfrak {f}}_{\mathfrak {s}}(\pi ) and the arithmetic first occurrence index f a ( π ) {\mathfrak {f}}_{{\mathfrak {a}}}(\pi ) of π \pi and prove in this paper that f s ( π ) = f a ( π ) {\mathfrak {f}}_{\mathfrak {s}}(\pi )={\mathfrak {f}}_{{\mathfrak {a}}}(\pi ) . Based on the theory of consecutive descents of enhanced L L -parameters developed by Jiang, Liu, and Zhang [Arithmetic wavefront sets and generic L L -packets, arXiv:2207.04700], we are able to show in this paper that the first descent spectrum consists of all discrete series representations, which determines explicitly the branching decomposition problem by means of the relevant arithmetic data and extends the main result (Jiang and Zhang [Algebra Number Theory 12 (2018), 1489–1535], Theorem 1.7) to broader generality.

Formononetin derivatives containing benzyl piperidine: A brand new, highly efficient inhibitor targeting Xanthomonas spp

IntroductionPlant bacterial diseases take an incalculable toll on global food security. The indiscriminate use of chemical synthetic pesticide not only facilitates pathogen resistance of pathogenic bacteria, but also poses a major threat to human health and environmental protection. Therefore, it is of great economic value and scientific significance to develop a new antibacterial drug with environmental friendliness and unique mechanism of action. ObjectivesTo design and synthesize formononetin derivatives based on natural products, evaluate their in vitro and in vivo antibacterial activities and elucidate the mechanisms involved. MethodsThe synthesis was carried out by classical active group splicing method. The antibacterial activities were evaluated using turbidimetry and pot experiments. The antibacterial mechanism was further investigated using scanning electron microscopy (SEM), virulence factors, defense enzymes activities, proteomics and metabolomics. Results40 formononetin derivatives containing benzyl piperidine were designed and synthesized. The antibacterial results demonstrated that H32 exhibited the most potent inhibitory effect against Xanthomonas oryzae pv. Oryzae (Xoo) with the EC50 of 0.07 μg/mL, while H6 displayed the highest inhibitory activity against Xanthomonas axonopodis pv. Citri (Xac) with the EC50 of 0.24 μg/mL. Furthermore, the control efficacy of H32 against rice bacterial leaf blight (BLB) and H6 against citrus canker (CC) was validated through pot experiments. SEM, virulence factors and host enzyme activities assay indicated that H32 could not only reduce the virulence of Xoo, but also activate the activities of defense enzymes and improve the disease resistance of host plants. The proteomics and metabolomics analysis demonstrated that H32 could inhibit the synthesis of branched-chain amino acids, make Xoo cells in a starvation state, inhibit its proliferation, weaken its virulence and reduce its colonization and infection of host cells. ConclusionFormononetin derivatives containing benzyl piperidine could be used as potentially effective inhibitors against Xanthomonas spp.

Medium-to Long-term Outcomes of Rex Shunt in 105 Children With Extrahepatic Portal Vein Obstruction in China

PurposeThe aim of our study was to analyze the medium-to long-term outcomes of Rex shunts in a large series of children with extrahepatic portal vein obstruction (EHPVO). MethodsThe clinical data of 105 children aged between 6 months and 16 years with EHPVO who underwent Rex shunt between October 2014 and June 2021 at our center were retrospectively reviewed after more than 2 years of follow-up. ResultsThe overall patency rate of the Rex shunt was 91.43% (96/105) during a median follow-up of 41 months (range, 24–98 months). Eighty-seven (82.86%) of the 105 patients underwent classical Rex shunt with internal jugular vein (IJV) bypass, and the remaining 18 patients (17.14%) underwent modified Rex shunt with intra-abdominal vein bypass. Patients with a patent shunt experienced portal hypertension resolution, which was characterized by a reduction in portal pressure, disappearance of variceal bleeding, relief of gastroesophageal varices, and relief of splenomegaly or hypersplenism. The rate of Rex shunt thrombosis in our center was 8.57% (9/105), and a repeat Rex shunt was effective for the treatment of graft thrombosis. Anastomotic stenosis occurred in 14.26% (15/105) of the children, 38.46% (5/13) of whom received successful endovascular intervention therapy and experienced remission of portal hypertension symptoms. The patency rate of the classical Rex shunt was higher than that of the modified Rex shunt (97.70% vs. 61.11%), whereas the rate of vascular complications, including anastomotic stenosis and graft thrombosis, of the classical Rex shunt was lower than that of the modified Rex shunt (11.49% vs. 77.78%). Further comparison revealed that the risk of vascular complications was substantially greater in the modified Rex shunt group than in the classical Rex shunt group in the nonadjusted model, minimally adjusted model, and fully adjusted model (RR ranged from 6.77 to 7.07, all p < 0.001). ConclusionsThe Rex shunt provides medium-to long-term benefits for children with EHPVO. The classical Rex shunt with IJV bypass provides the best patency rate and the fewest vascular complications. Levels of EvidenceⅢ Type of StudyRetrospective comparative study.

Delayed Gastric Emptying and Other Adverse Outcomes in Patients Undergoing Classic Whipple Versus Pylorus-Sparing Pancreatoduodenectomy.

Background and objective Pancreatoduodenectomy (PD), or the Whipple procedure, has many variants. There is a lack of data in the literature in terms of comparing various types of this procedure. This study aimed to comparethe classic Whipple procedure with the pylorus-sparing Transverso-Longmire technique, focusing on postoperative complications and delayed gastric emptying (DGE). Methodology We conducted a retrospective observational study including 97 adult patients who underwent either the classic Whipple procedure or the pylorus-sparing technique at Hospital Médica Sur from 2016 to 2021. Data on patient demographics, comorbidities, type of surgery, clinical presentation, and postoperative complications were collected. DGE was defined according to the International Study Group of Pancreatic Surgery(ISGPS) criteria. Results Among the 97 patients, 50.5% were men, and the median age of the cohort was 65 years. Almost all patients underwent surgery for malignancy (96.9%). The classic Whipple group had fewer cases of DGE (9.8% vs. 30.6%, p=0.01), shorter hospital stays (7 vs. 11 days, p=0.001), and lower readmission rates (13.1% vs. 33.3%, p=0.017). The pylorus-sparing PD was associated with a lower incidence of bile leak [odds ratio (OR)=0.62, 95% confidence interval (CI): 0.53-0.73]. However, this technique was associated with a higher incidence of DGE (OR=4, 95% CI: 1.34-12.1), overall hospital admission rates (OR=3.3, 95% CI: 1.2-9.2), and admissions that resulted in a surgical event (OR=1.9, 95% CI: 1.21-2.96). DGE was associated with the need for a second surgery (OR=10.5, 95% CI: 2.8-39.5) and hospital readmission (OR=10, 95% CI: 3.1-32.3). Conclusions While the pylorus-sparing technique is associated with reduced bile leaks, it results in a higher incidence of DGE, prolonged hospital stays, and increased readmissions. Clinicians opting for the pylorus-sparing technique should ensure careful patient selection and rigorous postoperative monitoring.

The Effects of Classical Music on Pain and Spinal Mobility During Stretching Exercises in Healthy Individuals

Aim: The aim of this study was to examine the immediate effects of listening to classical music as a cognitive relaxation technique during stretching exercises on trunk flexibility and exercise-induced pain. Method: This study was a randomized controlled trial in which 34 healthy male and female individuals aged between 18-22 years were divided into two groups: classical music listening group (n=17) and control group (n=17). Both groups performed static stretching exercises on the lumbal region and hamstring muscle groups for a total of 15 minutes. During the exercise, participants in the Classical Music Group listened to music with headphones. Control group did not listen to any music. Both groups underwent evaluation of their forward (Sit Reach Test) and lateral trunk flexibility (Trunk Lateral Flexion Test) before and after the exercise. Pain intensity during exercise was measured with Visual Analog Scale. Statistical analysis was performed using the R-Studio 1.4.1103 program, with a significance level of p&amp;lt;0.05. Results: In both groups, there was an increase in all flexibility values compared to before the stretching exercise (p&amp;lt;0.001). Classical Music Group demonstrated greater improvements in flexibility values compared to the Control Group, except for the forward flexibility of the trunk (p&amp;lt;0.05). The two groups had no significant difference in pain levels experienced during static stretching exercises (p&amp;gt;0.05). Conclusion: Performing stretching exercises while listening to classical music has been shown to increase the pain threshold. This decreased sensation of pain resulting from exercise can also lead to increased flexibility.

Feasibility and value of modular splenic hilar lymphadenectomy technique in laparoscopic total gastrectomy: a retrospective-controlled research.

This study aims to investigate the feasibility and value of modular splenic hilar lymphadenectomy (MSHL) in LTG for advanced PGC located at the greater curvature. A retrospective-controlled research included 54 patients diagnosed with advanced PGC located at the greater curvature who underwent LTG combined with spleen-preserving hilar lymphadenectomy between January 2020 and December 2022 at the same treatment center. A total of 20 patients underwent classic splenic hilar lymphadenectomy (CSHL) using a medial approach (classic group), while 34 patients underwent MSHL (modular group). We summarized the technical points, caveats, and critical steps of the MSHL technique and observed and compared clinical indexes between the two groups. All operations were successful without conversion to laparotomy. The mean operation time, mean splenic hilar lymph node dissection (LND) time, median intraoperative blood loss, and blood loss from splenic hilar LND were all significantly lower in the modular group than in the classic group (p < 0.05). The amount of NO.10 lymph nodes (LNs) was significantly higher in the modular group than in the classic group (p < 0.05). In the classic group, one patient experienced intraoperative splenic vein injury, and one experienced spleen laceration, whereas no intraoperative complications occurred in the modular group. The median postoperative feeding time, exhaust time, defecation time, and postoperative stay were all significantly lower in the modular group compared to the classic group (p < 0.05). In the modular group, one patient experienced Clavien-Dindo I complication and one Clavien-Dindo II complication, while in the classic group, one patient experienced Clavien-Dindo II complication and one Clavien-Dindo IIIa complication. There were no patient was re-hospitalized within 30days after surgery. The modular splenic hilar LND technique can simplify complicated surgical procedures in SPSHL and reduce the risk of intraoperative bleeding and collateral damage.

APTT and D-dimer as biomarkers for heatstroke in patients with severe heat-related illnesses.

The objective of this study was to analyze the changes of activated partial thromboplastin time (APTT) and D-dimer in severe heatstroke (HS) patients and their value in identifying HS patients and to analyze clinical features and early laboratory test results of heat-related illnesses. Forty-five patients with heat-related illnesses who were admitted to the Department of Emergency and Intensive Care Medicine of Suining Central Hospital from June 2022 to April 2023 were retrospectively analyzed. Patients were divided into 3 groups based on their clinical diagnosis: classic HS group, exertional HS group, and control group. General date and laboratory test results were collected, especially APTT and D-dimer. The receiver operating characteristic curve was used to analyze D-dimer and APTT. : There were differences in gender distribution among the 3 groups. Exertional HS was dominated by male patients, and classic HS was dominated by elderly patients. Binary logistic regression analysis of coagulation index showed a significant correlation between D-dimer and APTT and HS. The receiver operating characteristic curve results showed that APTT and D-dimer had high sensitivity and specificity in the identification of HS with an area under the curve (AUC) of 0.846, sensitivity of 97%, and specificity of 58.3% for APTT and an AUC of 0.861, sensitivity of 72%, and specificity of 91.7% for D-dimer (D-dimer + APTT [AUC, 0.929; sensitivity, 81.8%-91.7%; P < .001]). : The mortality rate of HS is high, and early diagnosis is particularly important. APTT and D-dimer may be used as markers assisting in identifying HS.

Small airway inflammation in atypical asthma

BackgroundLess attention has been paid to the pathophysiological changes in atypical asthma such as cough variant asthma (CVA) and chest tightness variant asthma (CTVA). The obstruction of large and small airways is the important component in the development of asthma. We investigated whether small airway inflammation (SAI) induced small airway dysfunction (SAD) in these atypical asthmatics. MethodsSix hundred and eighty-six patients were enrolled and analyzed in the study. The partitioned airway inflammation was assessed by fractional exhaled nitric oxide (FeNO), such as FnNO, FeNO50, FeNO200, and calculated alveolar fraction of exhaled NO (CaNOdual). Correlations between exhaled NOs and SAD-related variables were assessed, whereas cell classification was evaluated by Spearman's rank tests. Classic asthma, CVA, and CTVA about potential risk were conducted using binary logistic regression models. ResultsThe whole airway inflammation increased in classic and atypical asthma than controls, whereas the central and peripheral airway inflammation in the CVA and CTVA groups increased compared with the classic asthma group. Smoking exposure was found to increase the central and peripheral airway inflammation in patients with asthma. The exhaled NO of FeNO50 and FeNO200 was associated with SAD in classic asthma, but not in CVA and CTVA. FeNO200 was the main risk (adjusted odds ratio [OR], 1.591; 95 % CI, 1.121–2.259; P = .009) in classic asthma and (adjusted OR, 1.456; 95 % CI, 1.247–1.700; P = .000) in CVA. The blood eosinophil levels were correlated with FeNO50 and FeNO200 in classic asthma and atypical asthma. ConclusionMore severe inflammatory process was present in central and peripheral airways in CVA and CTVA, which might reflect a pre-asthmatic state. SAI was the predominant risk factor in the development of asthma before SAD.

Comparison of classical and patient-preferred music on anxiety and recovery after ınguinal hernia repair: a prospective randomized controlled study

BackgroundWe aimed to evaluate the effects of preoperative listening to patient-preferred music and classical music on postoperative anxiety and recovery.MethodsA prospective, randomized controlled, single-blind study included 255 patients who were scheduled for elective inguinal hernia operation under general anesthesia. Spielberger state State-Trait Anxiety Inventory form 1,2 (STAI-I, STAI-II), Quality of Recovery Score-40 (QoR-40) were applied in the preoperatively. In the preoperative period, the preferential music group (group P) patients listened to their favorite music, while patients in the classical music group (group C) listened to classical music, music was not played in the control group (group N). STAI-I, QoR-40 questionnaire, pain status, and patient satisfaction in the postoperative period were recorded by a blinded investigator.ResultsA total of 217 patients participated in the study analysis. Postoperative STAI-1 score was lower in group P than in group N (p = 0.025) and was similar among other groups. The postoperative QoR-40 score was significantly higher in group P than in group N (p = 0.003), and it was similar between the other groups. While SBP, DBP and HR premusic and post-music changes were significant, there was no difference in other groups. There was no difference between the groups in the NRS score. The patient satisfaction score was significantly higher in group P.ConclusionsPreoperative patient-preferred music application reduces postoperative anxiety and improves recovery quality compared to classical music. In addition, regulation of hemodynamic data and patient satisfaction increase in a preferential music application, but pain scores do not change.Trial registrationNCT04277559|https://www.clinicaltrials.gov/

Atypical and non-classical CD45RBlo memory B cells are the majority of circulating SARS-CoV-2 specific B cells following mRNA vaccination or COVID-19

Resting memory B cells can be divided into classical or atypical groups, but the heterogenous marker expression on activated memory B cells makes similar classification difficult. Here, by longitudinal analysis of mass cytometry and CITE-seq data from cohorts with COVID-19, bacterial sepsis, or BNT162b2 mRNA vaccine, we observe that resting B cell memory consist of classical CD45RB+ memory and CD45RBlo memory, of which the latter contains of two distinct groups of CD11c+ atypical and CD23+ non-classical memory cells. CD45RB levels remain stable in these cells after activation, thereby enabling the tracking of activated B cells and plasmablasts derived from either CD45RB+ or CD45RBlo memory B cells. Moreover, in both COVID-19 patients and mRNA vaccination, CD45RBlo B cells formed the majority of SARS-CoV2 specific memory B cells and correlated with serum antibodies, while CD45RB+ memory are activated by bacterial sepsis. Our results thus identify that stably expressed CD45RB levels can be exploited to trace resting memory B cells and their activated progeny, and suggest that atypical and non-classical CD45RBlo memory B cells contribute to SARS-CoV-2 infection and vaccination.

Perbedaan Pengaruh Jahe, Aromaterapi Oil Lavender dan Musik Klasik terhadap Pengurangan Emesis Gravidarum pada Ibu Hamil Trimester I

Emesis gravidarum is the most common disorder found in 70% of pregnant women. Nonpharmacological treatments that can be used are ginger, oil lavender aromatherapy, and classical music. The purpose of this study was to determine the differences in the effect of ginger, oil lavender aromatherapy, and classical music on reducing emesis gravidarum in the first trimester of pregnant women. The research method used a quasy-experiment with a three-group comparison pretest-posttest design in a time series. The sampling technique used purposive sampling, the sample size was 28 pregnant women in the working area of the Jogonalan II Health Center, 22 pregnant women in the Kebonarum Health Center, and 25 pregnant women in the Prambanan Health Center. Then divided into 3 groups, namely the ginger group, the oil lavender aromatherapy group, and the classical music group. Ginger reduced the emesis gravidarum score by 3,23. Oil lavender aromatherapy reduced the emesis gravidarum score by 4,42. Classical music lowers the emesis gravidarum score by 2,03. This study shows that there is an effect of reducing emesis gravidarum in first trimester pregnant women, but the difference in the effects is not significant because they have the same p value = 0,000 &lt;0,05.ginger, oil lavender aromatherapy, classical music, emesis gravidarum

Representations of group actions and their applications in cryptography

Cryptographic group actions provide a flexible framework that allows the instantiation of several primitives, ranging from key exchange protocols to PRFs and digital signatures. The security of such constructions is based on the intractability of some computational problems. For example, given the group action (G,X,⋆), the weak unpredictability assumption (Alamati et al. (2020) [1]) requires that, given random xi's in X, no probabilistic polynomial time algorithm can compute, on input {(xi,g⋆xi)}i=1,…,Q and y, the set element g⋆y.In this work, we study such assumptions, aided by the definition of group action representations and a new metric, the q-linear dimension, that estimates the “linearity” of a group action, or in other words, how much it is far from being linear. We show that under some hypotheses on the group action representation, and if the q-linear dimension is polynomial in the security parameter, then the weak unpredictability and other related assumptions cannot hold. This technique is applied to some actions from cryptography, like the ones arising from the equivalence of linear codes, as a result, we obtain the impossibility of using such actions for the instantiation of certain primitives.As an additional result, some bounds on the q-linear dimension are given for classical groups, such as Sn, GL(Fn) and the cyclic group Zn acting on itself.

Innovative pancreas-guided technique for splenic flexure mobilization in laparoscopic left hemicolectomy.

Splenic flexure mobilization (SFM) is a major challenge in laparoscopic left hemicolectomy. This study aims to assess the safety and effectiveness of the pancreas-guided SFM technique during laparoscopic left hemicolectomy. From January 2018 to December 2023, 352 patients with left-sided colon cancer underwent laparoscopic left hemicolectomy. Based on the SFM method used, the patients were divided into the pancreas-guided group (167 cases) or the "Three Approaches Roundabout"/classic group (185 cases). Clinicopathologic characteristics and intraoperative and postoperative variables were compared between the two groups. The two groups had no significant differences in baseline indicators (P > 0.05). All surgeries were successful without needing to convert to laparotomy, and there were no combined organ resections involving the spleen or pancreas in either group. The mean duration of surgery was significantly lower in the pancreas-guided group than in the classic group (P < 0.01). The median volume of intraoperative blood loss in the pancreas-guided group was lower than that in the classic group (P < 0.01). Through video playback, it was found that the retro-pancreaticspace had been entered during operation in 8 cases (4.3%) in the classic group, while there were no such occurrences in the pancreas-guided group. This difference was statistically significant (P < 0.05). The difference in the number of lymph nodes cleared, postoperative hospital stays, and incidence of complications were not statistically significant (all P > 0.05) between the groups. The pancreas-guided SFM technique is a safe and feasible option for laparoscopic left hemicolectomy. Our study's findings suggest that this approach facilitates accurate access to the correct anatomic plane, potentially improving surgical efficiency.

A comparison of the outcomes of tonsillectomy and expansion sphincter pharyngoplasty operations in patients with obstructive sleep apnea

ABSTRACT Objective To compare the efficacy of tonsillectomy and expansion sphincter pharyngoplasty (ESP) in the surgical treatment of obstructive sleep apnea (OSA). Methods OSA patients with Friedman grade III-IV tonsil hypertrophy diagnosed with polysomnography were separated into two groups according to the surgery performed, as the classic tonsillectomy group (Group 1) and the ESP group (Group 2). The primary endpoint of the study was to determine the Apnea-Hypopnea Index (AHI) value. Results Group 1 comprised 24 patients with median preoperative AHI of 19.7 and postoperative AHI of median 11.8 (p = .0001). Group 2 comprised 29 patients with median preoperative AHI of 25.1 and postoperative AHI of median 16.3 (p = .0001). Nine (37.5%) of the 24 patients in Group 1 accepted as cure (79.1%). Eight (27.5%) of the 29 patients in Group 2 accepted as cure (72.4%). Conclusion There was no superiority of ESP over tonsillectomy in patients with lateral pharyngeal obstruction.

Establishment and evaluation of a stable and reliable rat model of peritoneal adhesions

BackgroundIn this study, we aimed to establish a stable and standardized animal model of peritoneal adhesions. MethodsForty-eight male Sprague–Dawley rats were randomly divided (n = 12 each) into blank control, classic cecum sidewall, ischemic button, and cecum–sidewall suture groups. The modified American Fertility Society adhesion score was used on postoperative day 7 to evaluate adhesions. Sixty male Sprague–Dawley rats were used to dynamically observe the adhesion characteristics of cecum–sidewall ischemic injury suture model at different time points (n = 60, randomly divided into groups a–e with 12 rats each). The modified American Fertility Society and Zühlke histologic scoring systems, hematoxylin-eosin staining, Masson staining, and computed tomography of the abdomen were used to evaluate adhesions on postoperative days 1, 3, 5, 7, and 14. ResultsNo peritoneal adhesions were observed in the blank control group on postoperative day 7. In the classic cecum sidewall group, 8 rats had inconsistent adhesions, which had a modified American Fertility Society adhesion score of 2.25 ± 1.96. All rats in the ischemic button and cecum–sidewall suture groups developed significant adhesions with modified American Fertility Society scores of 3.08 ± 1.31 and 4.67 ± 0.78, respectively. When the modified American Fertility Society score was used, statistically significant differences were observed between the classic cecum sidewall groups and cecum–sidewall suture groups and between the ischemic button groups and cecum–sidewall suture groups. All animals in groups a–e developed adhesions; adhesion scores increased gradually with time. ConclusionsThe cecum–sidewall ischemic injury suture model is a stable and standardized animal model of peritoneal adhesions.

Bedtime music therapy for college students with insomnia: A randomized assessor-blinded controlled trial

BackgroundInsomnia, a prevalent sleep disorder in contemporary society, frequently coexists with other mental health conditions such as depression, schizophrenia, and obsessive-compulsive disorder. Sleep disorders can compromise daytime functioning and overall quality of life. While music has been explored as an adjunct therapy for insomnia, its efficacy in improving insomnia among students remains unclear. MethodsSeventy-five students, aged between 18 and 30 years with an average age of 20.97 years (SD: 1.92), presenting sleep issues were randomly allocated to one of three groups: the classical music group, the jazz music group, and the control group, each with 25 participants. Participants in the classical and jazz music group were instructed to listen to classical or jazz music for a minimum of 30 min preceding bedtime. This was paired with deep breathing and relaxation techniques, practiced two consecutive nights per week from 23:00 to 01:00 over a five-week intervention period. Conversely, participants in the control group were only directed to follow the deep breathing and relaxation techniques before sleep on two consecutive nights weekly.Insomnia severity with the Insomnia Severity Index (ISI), sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), depressive symptoms with the Beck Depression Inventory-II (BDI- II), and anxiety symptoms with the Self-rating Anxiety Scale (SAS). Measurements were taken at baseline, after the second week of intervention, at the intervention's conclusion (five weeks), and two months post-intervention (follow-up). Results1. The music groups showed a significant difference in insomnia severity compared with the control group after five weeks of intervention(p < .05). 2. music groups exhibited significant enhancements in sleep quality relative to the control group after a five-week intervention (p < .05). 3. Regarding mood enhancement, music groups showed significant improvements in depression and anxiety symptoms compared to the baseline after the five-week intervention. Notably, the control group also displayed improvements in these symptoms post-intervention. Conclusion1. Integrating music into a consistent bedtime routine ameliorates sleep quality and insomnia severity. However, no specific genre of music emerged as the superior choice for pre-sleep listening. 2. While music can considerably enhance mood indicators like depression and anxiety, techniques such as deep breathing and mindfulness also contribute positively. 3. Incorporating music before sleep tangibly elevates overall quality of life and daytime functioning. Trial registrationChiCTR2300073953.

CSI-Otter: isogeny-based (partially) blind signatures from the class group action with a twist

In this paper, we construct the first provably-secure isogeny-based (partially) blind signature scheme. While at a high level the scheme resembles the Schnorr blind signature, our work does not directly follow from that construction, since isogenies do not offer as rich an algebraic structure. Specifically, our protocol does not fit into the linear identification protocol abstraction introduced by Hauck, Kiltz, and Loss (EUROCYRPT’19), which was used to generically construct Schnorr-like blind signatures based on modules such as classical groups and lattices. Consequently, our scheme is provably secure in the random oracle model (ROM) against poly-logarithmically-many concurrent sessions assuming the subexponential hardness of the group action inverse problem. In more detail, our blind signature exploits the quadratic twist of an elliptic curve in an essential way to endow isogenies with a strictly richer structure than abstract group actions (but still more restrictive than modules). The basic scheme has public key size 128 B and signature size 8 KB under the CSIDH-512 parameter sets—these are the smallest among all provably secure post-quantum secure blind signatures. Relying on a new ring variant of the group action inverse problem (rGAIP\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ extsf{rGAIP}$$\\end{document}), we can halve the signature size to 4 KB while increasing the public key size to 512 B. We provide preliminary cryptanalysis of rGAIP\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$${\ extsf{rGAIP}} $$\\end{document} and show that for certain parameter settings, it is essentially as secure as the standard GAIP\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ extsf{GAIP}$$\\end{document}. Finally, we show a novel way to turn our blind signature into a partially blind signature, where we deviate from prior methods since they require hashing into the set of public keys while hiding the corresponding secret key—constructing such a hash function in the isogeny setting remains an open problem.

An adapted constraint‐programming formulation of the resource‐constrained project scheduling problem applied to the identical parallel machines group shop and mixed shop scheduling problems

AbstractIn this paper, we study the group shop and the mixed shop scheduling problems with single and identical parallel machines at each workstation with the makespan criterion. We adapted a constraint programming formulation previously presented for the classical resource‐constrained project scheduling problem. The effectiveness of our approach is evident in the fact that it achieved optimality in 107 out of 130 classical group shop scheduling problem instances and in 320 classical mixed shop scheduling problem instances. In the last set, we obtained 13 new optimal solutions.

The effects of connective tissue massage and classical massage on pain, lumbar mobility, function, disability, and well-being in chronic low back pain: A three-arm randomized controlled trial

BackgroundChronic low back pain (CLBP) is a common musculoskeletal disorder. Effect of massage in the management of CLBP has been documented, but it is not clear which massage regimen is more effective. This study was carried out to compare the effect of connective tissue massage and classical massage on pain, lumbar mobility, function, disability, and well-being among patients with CLBP. MethodsThe study included 30 participants who were randomly assigned to one of three intervention groups: the connective tissue massage group (CTMG; n = 10), the classical massage group (CMG; n = 10), and a standard physiotherapy/control group (CG; n = 10). The interventions were administered three times a week for four consecutive weeks. Assessments were conducted at baseline and at the end of the fourth week. Pain severity (Visual Analog Scale), lumbar mobility (Modified Schober Test), function (Back Pain Functional Scale), disability (Roland Morris Disability Questionnaire), and well-being (Short Form-36/SF-36) was evaluated. ResultsAll groups exhibited improvements in pain, lumbar mobility, function, and disability after 4 weeks (p < 0.05). The CMG showed enhancements in physical function, bodily pain, role physical, and role emotional subgroups of SF-36. The CTMG demonstrated improvements in all subgroups of SF-36 except general health (p < 0.05), while the CG only improved in the physical function subgroup (p < 0.05). A 2-way repeated measures ANOVA revealed a significant group-time interaction for MST (p = 0.04), Bodily Pain (p = 0.025) and Role Physical (p = 0.015). ConclusionsThe findings obtained from this study showed that CTMG was superior to CMG and CG in increasing lumbar mobility, and both massage applications were superior to the CG in increasing the well-being.

On an infinite family of integral Cayley graphs of Pauli groups

The classical Pauli group can be obtained as the central product of the dihedral group of 8 elements with the cyclic group of order 4. Inspired by this characterization, we introduce the notion of central product of Cayley graphs, which allows to regard the Cayley graph of a central product of groups as a quotient of the Cartesian product of the Cayley graphs of the factor groups. We focus our attention on the Cayley graph Cay(Pn,SPn) of the generalized Pauli group Pn on n-qubits; in fact, Pn may be decomposed as the central product of finite 2-groups, and a suitable choice of the generating set SPn allows us to recognize the structure of central product of graphs in Cay(Pn,SPn).Using this approach, we are able to recursively construct the adjacency matrix of Cay(Pn,SPn) for each n≥1, and to explicitly describe its spectrum and the associated eigenvectors. It turns out that Cay(Pn,SPn) is a (3n+2)-regular bipartite graph on 4n+1 vertices, and it has integral spectrum. This is a highly nontrivial property if one considers that, by choosing as a generating set for P1 the three classical Pauli matrices, one gets the so-called Möbius-Kantor graph, belonging to the class of generalized Petersen graphs, whose spectrum is not integral.